UY30533A1 - Acetamidas n-{1-[4(1-ciano-1-metil)fenil]etil}sustituidas derivadas del acido 2-(1h-bencimidazol-1il) acético - Google Patents

Acetamidas n-{1-[4(1-ciano-1-metil)fenil]etil}sustituidas derivadas del acido 2-(1h-bencimidazol-1il) acético

Info

Publication number
UY30533A1
UY30533A1 UY30533A UY30533A UY30533A1 UY 30533 A1 UY30533 A1 UY 30533A1 UY 30533 A UY30533 A UY 30533A UY 30533 A UY30533 A UY 30533A UY 30533 A1 UY30533 A1 UY 30533A1
Authority
UY
Uruguay
Prior art keywords
acetamids
bencimidazol
etil
ciano
acetic
Prior art date
Application number
UY30533A
Other languages
English (en)
Inventor
Denis Labrecque
Shawn Johnstone
William L Brown
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39033277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30533(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY30533A1 publication Critical patent/UY30533A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se proporcionan compuestos de acuerdo con la Formula I: que son utiles en el tratamiento del dolor.
UY30533A 2006-08-11 2007-08-10 Acetamidas n-{1-[4(1-ciano-1-metil)fenil]etil}sustituidas derivadas del acido 2-(1h-bencimidazol-1il) acético UY30533A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83724906P 2006-08-11 2006-08-11

Publications (1)

Publication Number Publication Date
UY30533A1 true UY30533A1 (es) 2008-03-31

Family

ID=39033277

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30533A UY30533A1 (es) 2006-08-11 2007-08-10 Acetamidas n-{1-[4(1-ciano-1-metil)fenil]etil}sustituidas derivadas del acido 2-(1h-bencimidazol-1il) acético

Country Status (25)

Country Link
US (2) US7906654B2 (es)
EP (1) EP2051967B1 (es)
JP (1) JP5140077B2 (es)
KR (1) KR101412881B1 (es)
CN (2) CN101792436A (es)
AR (1) AR062299A1 (es)
AU (1) AU2007282186B2 (es)
BR (1) BRPI0715746B8 (es)
CA (1) CA2660529C (es)
CL (1) CL2007002343A1 (es)
CO (1) CO6150176A2 (es)
ES (1) ES2533971T3 (es)
IL (1) IL196672A0 (es)
MX (1) MX2009001496A (es)
MY (1) MY147649A (es)
NO (1) NO20091054L (es)
NZ (1) NZ575416A (es)
PE (1) PE20081315A1 (es)
RU (1) RU2458055C2 (es)
SG (1) SG173360A1 (es)
TW (1) TWI433839B (es)
UA (1) UA96764C2 (es)
UY (1) UY30533A1 (es)
WO (1) WO2008018827A1 (es)
ZA (1) ZA200900961B (es)

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TWI433839B (zh) * 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
NZ587771A (en) 2008-04-18 2011-05-27 Dae Woong Pharma Novel benzoxazine benzimidazole derivatives, pharmaceutical composition comprising same, and a use thereof
KR101293384B1 (ko) 2010-10-13 2013-08-05 주식회사 대웅제약 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
MX2015000794A (es) 2012-07-18 2015-10-12 Univ Saint Louis Derivados de aminoácido beta como antagonistas de integrina.
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
JO3719B1 (ar) 2014-11-20 2021-01-31 Takeda Pharmaceuticals Co 4- أوكسو-4،3- داي هيدرو-3،2،1- بنزوترايازينات كمواد ضابطة لأجل gpr139
JP6853778B2 (ja) 2014-12-08 2021-03-31 ローム アンド ハース カンパニーRohm And Haas Company ポリオレフィン添加剤、耐垂下性ポリオレフィン、及びその調製方法
JP2018052817A (ja) * 2015-01-21 2018-04-05 大日本住友製薬株式会社 新規ベンズイミダゾール誘導体およびその医薬用途
CN108779077A (zh) 2015-12-30 2018-11-09 圣路易斯大学 作为pan整合素拮抗剂的间位氮杂环氨基苯甲酸衍生物
JP2022516362A (ja) * 2019-01-08 2022-02-25 ネオメド インスティテュート-インスティテュート ネオメド (s)-2-(7-シアノ-1h-ベンズイミダゾール-1イル)-n-{1-[4-(1-シアノ-1-メチルエチル)フェニル]エチル}アセトアミドの結晶形態
RU2755206C1 (ru) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Средство пролонгированного анальгетического действия и лекарственный препарат на его основе

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UY30048A1 (es) * 2005-12-23 2007-07-31 Astrazeneca Ab Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones
TWI433839B (zh) 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290

Also Published As

Publication number Publication date
PE20081315A1 (es) 2008-11-08
EP2051967A4 (en) 2011-06-29
US20080221188A1 (en) 2008-09-11
US7906654B2 (en) 2011-03-15
US8093402B2 (en) 2012-01-10
JP5140077B2 (ja) 2013-02-06
ZA200900961B (en) 2010-07-28
EP2051967B1 (en) 2014-12-31
MX2009001496A (es) 2009-02-18
AU2007282186A1 (en) 2008-02-14
CA2660529A1 (en) 2008-02-14
KR20090035701A (ko) 2009-04-10
CL2007002343A1 (es) 2008-04-04
WO2008018827A1 (en) 2008-02-14
US20110137045A1 (en) 2011-06-09
CO6150176A2 (es) 2010-04-20
CA2660529C (en) 2014-10-21
ES2533971T3 (es) 2015-04-16
JP2010500345A (ja) 2010-01-07
BRPI0715746A2 (pt) 2013-07-16
TW200817338A (en) 2008-04-16
WO2008018827A8 (en) 2009-02-19
EP2051967A1 (en) 2009-04-29
TWI433839B (zh) 2014-04-11
BRPI0715746B1 (pt) 2020-09-24
AU2007282186B2 (en) 2011-07-07
AR062299A1 (es) 2008-10-29
SG173360A1 (en) 2011-08-29
RU2458055C2 (ru) 2012-08-10
CN101792436A (zh) 2010-08-04
NZ575416A (en) 2011-10-28
CN101522637A (zh) 2009-09-02
IL196672A0 (en) 2009-11-18
BRPI0715746B8 (pt) 2021-05-25
RU2009103675A (ru) 2010-09-20
NO20091054L (no) 2009-03-09
KR101412881B1 (ko) 2014-06-26
UA96764C2 (ru) 2011-12-12
MY147649A (en) 2012-12-31

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