ZA200406755B - Oxa-and thiadiazoles and their use as metalloproteinase inhibitors - Google Patents
Oxa-and thiadiazoles and their use as metalloproteinase inhibitors Download PDFInfo
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- ZA200406755B ZA200406755B ZA200406755A ZA200406755A ZA200406755B ZA 200406755 B ZA200406755 B ZA 200406755B ZA 200406755 A ZA200406755 A ZA 200406755A ZA 200406755 A ZA200406755 A ZA 200406755A ZA 200406755 B ZA200406755 B ZA 200406755B
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- alkyl
- phenyl
- compound
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- alkenyl
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- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0204159.8A GB0204159D0 (en) | 2002-02-22 | 2002-02-22 | Metalloproteinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200406755B true ZA200406755B (en) | 2006-07-26 |
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Family Applications (1)
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| ZA200406755A ZA200406755B (en) | 2002-02-22 | 2004-08-25 | Oxa-and thiadiazoles and their use as metalloproteinase inhibitors |
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| EP (1) | EP1476438B1 (es) |
| JP (1) | JP4615864B2 (es) |
| KR (1) | KR101098614B1 (es) |
| CN (1) | CN100351245C (es) |
| AT (1) | ATE360007T1 (es) |
| AU (1) | AU2003205910B2 (es) |
| BR (1) | BR0307899A (es) |
| CA (1) | CA2475867C (es) |
| CY (1) | CY1106730T1 (es) |
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| DK (1) | DK1476438T3 (es) |
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| ES (1) | ES2286404T3 (es) |
| GB (1) | GB0204159D0 (es) |
| HK (1) | HK1078583A1 (es) |
| HR (1) | HRP20040725A2 (es) |
| IL (1) | IL163413A (es) |
| MX (1) | MXPA04008132A (es) |
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| PL (1) | PL210773B1 (es) |
| PT (1) | PT1476438E (es) |
| RS (1) | RS51354B (es) |
| SI (1) | SI1476438T1 (es) |
| UA (1) | UA78275C2 (es) |
| WO (1) | WO2003070711A1 (es) |
| ZA (1) | ZA200406755B (es) |
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| AU2003227952A1 (en) * | 2003-05-17 | 2004-12-03 | British Biotech Pharmaceuticals Ltd | Metalloproteinase inhibitors |
| US7786121B2 (en) * | 2003-08-23 | 2010-08-31 | Vernalis (Oxford) Limited | Derivatives of hydroxamic acid as metalloproteinase inhibitors |
| US7838522B2 (en) | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
| CN101124213B (zh) | 2004-12-21 | 2012-02-01 | 默克雪兰诺有限公司 | 磺酰氨基环状衍生物及其应用 |
| KR20070105326A (ko) | 2005-01-31 | 2007-10-30 | 라보라뚜와르 세로노 에스. 에이. | Ｎ-하이드록시아미드 유도체 및 그것의 용도 |
| BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 ｊｎｋ 억제제 |
| AU2006286489B2 (en) | 2005-09-01 | 2012-08-09 | Ares Trading S.A. | Treatment of optic neuritis |
| US8153166B2 (en) * | 2006-06-08 | 2012-04-10 | Chih-Hsiung Lin | Composition for prophylaxis or treatment of urinary system infection and method thereof |
| HUE038169T2 (hu) | 2013-09-06 | 2018-09-28 | Aurigene Discovery Tech Ltd | 1,2,4-Oxadiazol származékok mint immunomodulátorok |
| MY196130A (en) | 2015-03-10 | 2023-03-16 | Aurigene Discovery Tech Ltd | 1,2,4-Oxadiazole and Thiadiazole Compounds as Immunomodulators |
| CA2979161A1 (en) * | 2015-03-10 | 2016-09-15 | Aurigene Discovery Technologies Limited | 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| CN105384736B (zh) * | 2015-10-28 | 2018-11-02 | 南昌大学 | 一种ⅳ型胶原酶抑制剂及合成方法 |
| WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
| CA3078872A1 (en) | 2017-10-11 | 2019-04-18 | Aurigene Discovery Technologies Limited | Crystalline forms of 3-substituted 1,2,4-oxadiazole |
| SG11202003625VA (en) | 2017-11-03 | 2020-05-28 | Aurigene Discovery Tech Ltd | Dual inhibitors of tim-3 and pd-1 pathways |
| JP7378395B2 (ja) | 2017-11-06 | 2023-11-13 | オーリジーン オンコロジー リミテッド | 免疫調節のためのコンジョイントセラピー |
| CN108530378B (zh) * | 2018-05-29 | 2021-09-14 | 济南大学 | 一类含有噁二唑结构的氮原子双取代异羟肟酸类化合物、用途及其制备方法 |
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| GB9404046D0 (en) | 1994-03-03 | 1994-04-20 | Smithkline Beecham Corp | Novel compounds |
| US5665753A (en) * | 1994-03-03 | 1997-09-09 | Smithkline Beecham Corporation | Cytokine inhibiting imidazole substituted hydroxamic acid derivatives |
| US5703092A (en) * | 1995-04-18 | 1997-12-30 | The Dupont Merck Pharmaceutical Company | Hydroxamic acid compounds as metalloprotease and TNF inhibitors |
| PT946166E (pt) * | 1996-12-17 | 2004-06-30 | Warner Lambert Co | Utilizacao de inibidores das metaloproteinases da matriz para tratar disturbios neurologicos e promover a cicatrizacao de feridas |
| JP2002506873A (ja) * | 1998-03-18 | 2002-03-05 | アリアド・ファーマシューティカルズ・インコーポレイテッド | 複素環式シグナル伝達阻害剤、それを含む組成物 |
| JP2001031637A (ja) * | 1999-05-17 | 2001-02-06 | Fuji Chemical Industries Ltd | 新規なヒドロキサム酸誘導体 |
| GB9930570D0 (en) * | 1999-12-23 | 2000-02-16 | Pfizer Ltd | Therapy |
| US6448278B2 (en) * | 1999-12-23 | 2002-09-10 | Pfizer Inc. | Procollagen C-proteinase inhibitors |
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- 2003-02-20 UA UA20040806941A patent/UA78275C2/uk unknown
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2004
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2006
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2010
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