ZA200305642B - Method for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors. - Google Patents
Method for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors. Download PDFInfo
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- ZA200305642B ZA200305642B ZA200305642A ZA200305642A ZA200305642B ZA 200305642 B ZA200305642 B ZA 200305642B ZA 200305642 A ZA200305642 A ZA 200305642A ZA 200305642 A ZA200305642 A ZA 200305642A ZA 200305642 B ZA200305642 B ZA 200305642B
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- A61K49/00—Preparations for testing in vivo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- C—CHEMISTRY; METALLURGY
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
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- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
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Applications Claiming Priority (1)
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| US09/799,978 US6670140B2 (en) | 2001-03-06 | 2001-03-06 | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
Publications (1)
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|---|---|
| ZA200305642B true ZA200305642B (en) | 2004-06-22 |
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| ZA200305642A ZA200305642B (en) | 2001-03-06 | 2003-07-22 | Method for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors. |
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| RU (1) | RU2260805C2 (xx) |
| SA (1) | SA02230159B1 (xx) |
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| WO (1) | WO2002069908A2 (xx) |
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| AU2001284683B2 (en) * | 2000-08-04 | 2006-04-27 | Research Development Foundation | Urocortin proteins and uses thereof |
| CA2427490A1 (en) * | 2000-09-22 | 2002-03-28 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr) |
| US6670140B2 (en) * | 2001-03-06 | 2003-12-30 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
| US6936585B2 (en) * | 2002-01-16 | 2005-08-30 | The Procter & Gamble Company | Corticotropin releasing factor 2 receptor agonists |
| WO2007090087A2 (en) * | 2006-01-27 | 2007-08-09 | Research Development Foundation | Use of corticotropin releasing factor receptor-2 inhibitors for treating insulin-related diseases |
| EP2114437A2 (en) * | 2006-10-16 | 2009-11-11 | ConjuChem Biotechnologies Inc. | Modified corticotropin releasing factor peptides and uses thereof |
| GB0624282D0 (en) * | 2006-12-05 | 2007-01-10 | Cavalla David | Treatment of cachexia |
| AU2008255927B2 (en) * | 2007-05-23 | 2012-12-13 | Nippon Chemiphar Co., Ltd. | G-protein-conjugated receptor having altered ligand affinity, and use thereof |
| WO2010036918A2 (en) * | 2008-09-26 | 2010-04-01 | University Of Massachusetts | Intracellular dna receptor |
| EP3278800B1 (en) * | 2010-12-23 | 2019-04-10 | Amazentis SA | Compositions and methods for improving mitochondrial function and treating muscle-related pathological conditions |
| ES2663946T3 (es) * | 2011-11-14 | 2018-04-17 | Regeneron Pharmaceuticals, Inc. | Composiciones y métodos para aumentar la masa y la fuerza muscular antagonizando específicamente GDF8 y/o Activina A |
| RU2517259C1 (ru) * | 2013-03-06 | 2014-05-27 | Федеральное государственное бюджетное учреждение науки Государственный научный центр Российской Федерации - Институт медико-биологических проблем Российской академии наук (ГНЦ РФ-ИМБП РАН) | Способ профилактики и снижения деструкции белков скелетных мышц при их атрофии, вызванной гипокинезией и/или гравитационной разгрузкой |
| JP2015071549A (ja) * | 2013-10-02 | 2015-04-16 | 株式会社ファンケル | アトロジン−１抑制剤 |
| RU2568903C2 (ru) * | 2014-04-07 | 2015-11-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ оценки анаболического действия лекарственных препаратов |
| EP3283519A1 (en) | 2015-04-15 | 2018-02-21 | Regeneron Pharmaceuticals, Inc. | Methods of increasing strength and functionality with gdf8 inhibitors |
| MX2019004401A (es) * | 2016-10-20 | 2019-09-26 | Cortene Inc | Metodos de tratamiento y enfermedades resultantes de una respuesta de tension mal adaptada. |
| KR20200128125A (ko) | 2018-03-01 | 2020-11-11 | 리제너론 파아마슈티컬스, 인크. | 신체 조성을 변경하기 위한 방법 |
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| US4415558A (en) | 1981-06-08 | 1983-11-15 | The Salk Institute For Biological Studies | CRF And analogs |
| WO1984001378A1 (en) | 1982-09-29 | 1984-04-12 | Karl P Lederis | Urotensin peptides |
| US4489163A (en) | 1983-04-14 | 1984-12-18 | The Salk Institute For Biological Studies | rCRF and analogs |
| US4605642A (en) | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
| US4594329A (en) | 1984-05-14 | 1986-06-10 | The Salk Institute For Biological Studies | CRF analogs |
| US4801612A (en) * | 1986-07-03 | 1989-01-31 | Regents Of The University Of California | Method of inhibiting inflammatory response |
| DE3703340A1 (de) * | 1987-02-04 | 1988-08-18 | Dirck Dr Med Oppermann | Pharmazeutische zubereitung zur behandlung der herzinsuffizienz |
| US4908352A (en) | 1987-09-28 | 1990-03-13 | The Salk Institute For Biological Studies | Urotensin peptides |
| US5109111A (en) | 1988-09-23 | 1992-04-28 | The Salk Institute For Biological Studies | CRF antagonists |
| CA1340964C (en) * | 1988-09-30 | 2000-04-18 | Jean E. F. Rivier | Crf analogs |
| US5278146A (en) | 1988-09-30 | 1994-01-11 | The Salk Institute For Biological Studies | CRF analogs |
| US5235036A (en) | 1991-05-31 | 1993-08-10 | The Salk Institute For Biological Studies | Crf analogs |
| US5493006A (en) | 1993-06-16 | 1996-02-20 | The Salk Institute For Biological Studies | Cyclic CRF analogs |
| US5728545A (en) | 1993-06-18 | 1998-03-17 | The Salk Institute Of Biological Studies | Cloning and recombinant production of CRF receptor (S) |
| US6495343B1 (en) * | 1993-06-18 | 2002-12-17 | The Salk Institute For Biological Studies | Cloning and recombinant production of CRF receptor(s) |
| US5786203A (en) * | 1994-06-14 | 1998-07-28 | Neurocrine Biosciences, Inc. | Isolated nucleic acid encoding corticotropin-releasing factor2 receptors |
| DK0724637T4 (da) * | 1994-06-14 | 2002-09-16 | Neurocrine Biosciences Inc | Kortikotropinfrigørende faktor2-receptorer |
| EP0860501A3 (en) | 1994-06-14 | 1999-05-19 | Neurocrine Biosciences, Inc. | Corticotropin-releasing factor2 receptors |
| US5824771A (en) | 1994-12-12 | 1998-10-20 | The Salk Institute For Biological Studies | Cyclic CRF agonists |
| US5663292A (en) | 1994-12-12 | 1997-09-02 | The Salk Institute For Biological Studies | Cyclic CRF analogs |
| US5660824A (en) | 1995-05-24 | 1997-08-26 | Grabstein; Kenneth H. | Muscle trophic factor |
| CA2223792A1 (en) | 1995-06-13 | 1997-01-03 | The Salk Institute For Biological Studies | Urocortin peptides |
| US5869450A (en) | 1996-03-06 | 1999-02-09 | The Regents Of The University Of California | Anti-inflammatory compositions and method with corticotropin-releasing factor analogs |
| US5888811A (en) | 1996-05-23 | 1999-03-30 | Dupont Pharmaceuticals Company | Corticotropin-releasing hormone receptor |
| ATE354587T1 (de) * | 1998-07-24 | 2007-03-15 | Max Planck Gesellschaft | Für den corticotropin-releasing-factor-typ-2- rezeptor (crfr2) spezifische antagonisten |
| AU2001284683B2 (en) * | 2000-08-04 | 2006-04-27 | Research Development Foundation | Urocortin proteins and uses thereof |
| US6670140B2 (en) * | 2001-03-06 | 2003-12-30 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
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