MA26990A1 - Procedes d'identification de composes pour reguler la masse ou la fonction musculaire utilisant des recepteurs de facteur de liberation de la corticotropine. - Google Patents
Procedes d'identification de composes pour reguler la masse ou la fonction musculaire utilisant des recepteurs de facteur de liberation de la corticotropine.Info
- Publication number
- MA26990A1 MA26990A1 MA27267A MA27267A MA26990A1 MA 26990 A1 MA26990 A1 MA 26990A1 MA 27267 A MA27267 A MA 27267A MA 27267 A MA27267 A MA 27267A MA 26990 A1 MA26990 A1 MA 26990A1
- Authority
- MA
- Morocco
- Prior art keywords
- crf2r
- methods
- mass
- function
- corticotropin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
Abstract
PROCEDES POUR IDENTIFIER DES COMPOSES POUR REGULER LA MASSE OU LA FONCTION MUSCULAIRE EN UTILISANT DES RECEPTEURS DE FACTEURS LIBERATEURS DE CORTICOTROPINE THE PROCTER & GAMBLE COMPANY Invention de : ISFORT Robert SHELDON Russell Priorité : demande de brevet déposée aux Etats-Unis le 6 mars 2001 sous le no. 09/799,978 Procédés de criblage pour identifier des composés qui se lient à des récepteurs de facteurs 2 libérant de la corticotropine (CRF2R) ou activent ceux-ci et régulent ou régulent potentiellement la masse ou la fonction des muscles squelettiques in vivo. On décrit également des procédés de criblage pour identifier des composés qui prolongent ou augmentent l'activation des CRF2R ou de trajets de transduction de signaux des CRF2R, augmentent les CRF2R ou augmentent l'expression des CRF. On décrit également des compositions pharmaceutiques comprenant des agonistes de CRF2R, des anticorps aux CRF2R et des procédés permettant d'augmenter la masse ou la fonction des muscles squelettiques ou pour le traitement de l'atrophie des muscles squelettiques en utilisant des CRF2R comme cible pour l'intervention et des procédés de traitement de dystrophies usculaires.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/799,978 US6670140B2 (en) | 2001-03-06 | 2001-03-06 | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
MA26990A1 true MA26990A1 (fr) | 2004-12-20 |
Family
ID=25177205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA27267A MA26990A1 (fr) | 2001-03-06 | 2003-08-07 | Procedes d'identification de composes pour reguler la masse ou la fonction musculaire utilisant des recepteurs de facteur de liberation de la corticotropine. |
Country Status (28)
Country | Link |
---|---|
US (3) | US6670140B2 (fr) |
EP (1) | EP1379873B1 (fr) |
JP (2) | JP4331942B2 (fr) |
KR (2) | KR100598441B1 (fr) |
CN (1) | CN100520408C (fr) |
AR (1) | AR032957A1 (fr) |
AT (1) | ATE429242T1 (fr) |
AU (1) | AU2002303121B2 (fr) |
BR (1) | BR0207881A (fr) |
CA (1) | CA2439170C (fr) |
CZ (1) | CZ20032395A3 (fr) |
DE (1) | DE60232063D1 (fr) |
ES (1) | ES2325485T3 (fr) |
HU (1) | HUP0402173A2 (fr) |
IL (1) | IL157330A0 (fr) |
MA (1) | MA26990A1 (fr) |
MX (1) | MXPA03008114A (fr) |
MY (1) | MY134755A (fr) |
NO (1) | NO20033936L (fr) |
NZ (1) | NZ527124A (fr) |
PE (1) | PE20020993A1 (fr) |
PL (1) | PL367187A1 (fr) |
RU (1) | RU2260805C2 (fr) |
SA (1) | SA02230159B1 (fr) |
SK (1) | SK12132003A3 (fr) |
TW (1) | TWI227780B (fr) |
WO (1) | WO2002069908A2 (fr) |
ZA (1) | ZA200305642B (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2418144C (fr) * | 2000-08-04 | 2013-06-18 | Research Development Foundation | Proteines urocortines et utilisations |
US20040049009A1 (en) * | 2000-09-22 | 2004-03-11 | Klaus Eckart | Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr) |
US6670140B2 (en) * | 2001-03-06 | 2003-12-30 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
US6936585B2 (en) * | 2002-01-16 | 2005-08-30 | The Procter & Gamble Company | Corticotropin releasing factor 2 receptor agonists |
US7815905B2 (en) * | 2006-01-27 | 2010-10-19 | Research Development Foundation | Methods of increasing insulin sensitivity or decreasing insulin secretion by administering corticotropin releasing factor receptor-2 inhibitors |
US7982018B2 (en) * | 2006-10-16 | 2011-07-19 | Conjuchem, Llc | Modified corticotropin releasing factor peptides and uses thereof |
GB0624282D0 (en) * | 2006-12-05 | 2007-01-10 | Cavalla David | Treatment of cachexia |
KR20100017666A (ko) * | 2007-05-23 | 2010-02-16 | 파마콤 엘엘씨 | 리간드 친화성이 개질된 g단백질 공액형 수용체 및 그 용도 |
WO2010036918A2 (fr) * | 2008-09-26 | 2010-04-01 | University Of Massachusetts | Récepteur intracellulaire d'adn |
EP3369420A1 (fr) * | 2010-12-23 | 2018-09-05 | Amazentis SA | Compositions et procédés pour améliorer la fonction mitochondriale ettraiter des maladies neurodégénératives et des troubles cognitifs |
MX350355B (es) * | 2011-11-14 | 2017-09-04 | Regeneron Pharma | Composiciones y metodos para aumentar la masa muscular y la fuerza muscular antagonizando especificamente gdf8 y/o activina a. |
RU2517259C1 (ru) * | 2013-03-06 | 2014-05-27 | Федеральное государственное бюджетное учреждение науки Государственный научный центр Российской Федерации - Институт медико-биологических проблем Российской академии наук (ГНЦ РФ-ИМБП РАН) | Способ профилактики и снижения деструкции белков скелетных мышц при их атрофии, вызванной гипокинезией и/или гравитационной разгрузкой |
JP2015071549A (ja) * | 2013-10-02 | 2015-04-16 | 株式会社ファンケル | アトロジン−1抑制剤 |
RU2568903C2 (ru) * | 2014-04-07 | 2015-11-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ оценки анаболического действия лекарственных препаратов |
WO2016168613A1 (fr) | 2015-04-15 | 2016-10-20 | Regeneron Pharmaceuticals, Inc. | Méthode pour augmenter la résistance et la fonctionnalité avec des inhibiteurs de gdf-8 |
CA3040889A1 (fr) | 2016-10-20 | 2018-04-26 | Cortene Inc. | Methodes de traitement de maladies dues a une reponse au stress inadaptee |
JP2021515003A (ja) | 2018-03-01 | 2021-06-17 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 体組成を変更するための方法 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4415558A (en) * | 1981-06-08 | 1983-11-15 | The Salk Institute For Biological Studies | CRF And analogs |
WO1984001378A1 (fr) * | 1982-09-29 | 1984-04-12 | Karl P Lederis | Peptides d'urotensine |
US4489163A (en) * | 1983-04-14 | 1984-12-18 | The Salk Institute For Biological Studies | rCRF and analogs |
US4605642A (en) * | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
US4594329A (en) * | 1984-05-14 | 1986-06-10 | The Salk Institute For Biological Studies | CRF analogs |
US4801612A (en) * | 1986-07-03 | 1989-01-31 | Regents Of The University Of California | Method of inhibiting inflammatory response |
DE3703340A1 (de) * | 1987-02-04 | 1988-08-18 | Dirck Dr Med Oppermann | Pharmazeutische zubereitung zur behandlung der herzinsuffizienz |
US4908352A (en) * | 1987-09-28 | 1990-03-13 | The Salk Institute For Biological Studies | Urotensin peptides |
US5109111A (en) * | 1988-09-23 | 1992-04-28 | The Salk Institute For Biological Studies | CRF antagonists |
US5278146A (en) * | 1988-09-30 | 1994-01-11 | The Salk Institute For Biological Studies | CRF analogs |
CA1340964C (fr) * | 1988-09-30 | 2000-04-18 | Jean E. F. Rivier | Analogues du crf |
US5235036A (en) * | 1991-05-31 | 1993-08-10 | The Salk Institute For Biological Studies | Crf analogs |
US5493006A (en) * | 1993-06-16 | 1996-02-20 | The Salk Institute For Biological Studies | Cyclic CRF analogs |
US5728545A (en) * | 1993-06-18 | 1998-03-17 | The Salk Institute Of Biological Studies | Cloning and recombinant production of CRF receptor (S) |
US6495343B1 (en) * | 1993-06-18 | 2002-12-17 | The Salk Institute For Biological Studies | Cloning and recombinant production of CRF receptor(s) |
EP0860501A3 (fr) | 1994-06-14 | 1999-05-19 | Neurocrine Biosciences, Inc. | Récepteurs du facteur 2 libérant la corticotropine |
ES2123269T5 (es) * | 1994-06-14 | 2002-11-01 | Neurocrine Biosciences Inc | Receptores del factor 2 de liberacion de corticotropina. |
US5786203A (en) * | 1994-06-14 | 1998-07-28 | Neurocrine Biosciences, Inc. | Isolated nucleic acid encoding corticotropin-releasing factor2 receptors |
US5663292A (en) | 1994-12-12 | 1997-09-02 | The Salk Institute For Biological Studies | Cyclic CRF analogs |
US5824771A (en) | 1994-12-12 | 1998-10-20 | The Salk Institute For Biological Studies | Cyclic CRF agonists |
US5660824A (en) | 1995-05-24 | 1997-08-26 | Grabstein; Kenneth H. | Muscle trophic factor |
AU6277796A (en) | 1995-06-13 | 1997-01-15 | Salk Institute For Biological Studies, The | Urocortin peptides |
US5869450A (en) | 1996-03-06 | 1999-02-09 | The Regents Of The University Of California | Anti-inflammatory compositions and method with corticotropin-releasing factor analogs |
US5888811A (en) * | 1996-05-23 | 1999-03-30 | Dupont Pharmaceuticals Company | Corticotropin-releasing hormone receptor |
EP1100819B1 (fr) * | 1998-07-24 | 2007-02-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Antagonistes specifiques du recepteur de la corticoliberine de type 2 (crfr2) |
CA2418144C (fr) * | 2000-08-04 | 2013-06-18 | Research Development Foundation | Proteines urocortines et utilisations |
US6670140B2 (en) * | 2001-03-06 | 2003-12-30 | The Procter & Gamble Company | Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors |
-
2001
- 2001-03-06 US US09/799,978 patent/US6670140B2/en not_active Expired - Lifetime
-
2002
- 2002-03-05 PE PE2002000176A patent/PE20020993A1/es not_active Application Discontinuation
- 2002-03-05 TW TW091104025A patent/TWI227780B/zh not_active IP Right Cessation
- 2002-03-06 RU RU2003129500/15A patent/RU2260805C2/ru not_active IP Right Cessation
- 2002-03-06 NZ NZ527124A patent/NZ527124A/en unknown
- 2002-03-06 MX MXPA03008114A patent/MXPA03008114A/es active IP Right Grant
- 2002-03-06 KR KR1020067005678A patent/KR100598441B1/ko not_active IP Right Cessation
- 2002-03-06 ES ES02731122T patent/ES2325485T3/es not_active Expired - Lifetime
- 2002-03-06 AT AT02731122T patent/ATE429242T1/de not_active IP Right Cessation
- 2002-03-06 MY MYPI20020802A patent/MY134755A/en unknown
- 2002-03-06 HU HU0402173A patent/HUP0402173A2/hu unknown
- 2002-03-06 AR ARP020100806A patent/AR032957A1/es not_active Application Discontinuation
- 2002-03-06 WO PCT/US2002/007476 patent/WO2002069908A2/fr active IP Right Grant
- 2002-03-06 KR KR1020037011659A patent/KR100596991B1/ko not_active IP Right Cessation
- 2002-03-06 EP EP02731122A patent/EP1379873B1/fr not_active Expired - Lifetime
- 2002-03-06 CA CA2439170A patent/CA2439170C/fr not_active Expired - Fee Related
- 2002-03-06 CZ CZ20032395A patent/CZ20032395A3/cs unknown
- 2002-03-06 DE DE60232063T patent/DE60232063D1/de not_active Expired - Lifetime
- 2002-03-06 AU AU2002303121A patent/AU2002303121B2/en not_active Ceased
- 2002-03-06 BR BR0207881-3A patent/BR0207881A/pt not_active IP Right Cessation
- 2002-03-06 IL IL15733002A patent/IL157330A0/xx unknown
- 2002-03-06 JP JP2002569086A patent/JP4331942B2/ja not_active Expired - Fee Related
- 2002-03-06 CN CNB028059271A patent/CN100520408C/zh not_active Expired - Fee Related
- 2002-03-06 SK SK1213-2003A patent/SK12132003A3/sk unknown
- 2002-03-06 PL PL02367187A patent/PL367187A1/xx not_active Application Discontinuation
- 2002-06-19 SA SA02230159A patent/SA02230159B1/ar unknown
-
2003
- 2003-07-22 ZA ZA200305642A patent/ZA200305642B/en unknown
- 2003-08-07 MA MA27267A patent/MA26990A1/fr unknown
- 2003-08-27 US US10/649,852 patent/US7063954B2/en not_active Expired - Lifetime
- 2003-09-05 NO NO20033936A patent/NO20033936L/no not_active Application Discontinuation
-
2006
- 2006-04-26 US US11/412,025 patent/US7572768B2/en not_active Expired - Fee Related
-
2008
- 2008-09-01 JP JP2008224143A patent/JP2009029816A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA26990A1 (fr) | Procedes d'identification de composes pour reguler la masse ou la fonction musculaire utilisant des recepteurs de facteur de liberation de la corticotropine. | |
Boie et al. | Cloning and expression of a cDNA for the human prostanoid IP receptor. | |
EP0911321A3 (fr) | Composés pour le traitement de l'ostéoporose | |
NO20022655L (no) | <Beta>-2-adrenerge reseptoragonister | |
EP1308461A3 (fr) | Anticorps contre des bèta-amyloides ou leurs dérivés, et leurs utilisations | |
BRPI0410746A (pt) | compostos e composições imunossupressoras | |
TR200100267T2 (tr) | İkameli anilid bileşimleri ve yöntemler. | |
BG109311A (en) | PHARMACEUTICAL COMPOSITION, INCLUDING HUMAN ANTIBODIES CONNECTING HUMAN TNFAL, AND HIS APPLICATION | |
MA30555B1 (fr) | Procedes d'utilisation du recepteur gpr119 pour identifier des composes utiles pour augmenter la masse osseuse chez un individu | |
WO2002085285A3 (fr) | Methodes et compositions permettant de reguler la formation osseuse et cartilagineuse | |
ATE275562T1 (de) | Neue form vom irbesartan, verfahren um diese form zu erhalten und sie enthaltende pharmazeutische zusammensetzungen | |
WO1998058911A3 (fr) | Agonistes de prostaglandines | |
BR0215801A (pt) | Derivados de 3,6-dissubstituìdos azabiciclo [3.1.0] hexano úteis como antagonistas de receptores muscarìnicos | |
ATE396969T1 (de) | 3,6-disubstituierte azabicyclo (3.1.0)hexanderivate, die sich als muscarinrezeptorantagonisten eignen | |
EP0801049A3 (fr) | Dérivés de cyclopentanebutanol comme matières odorantes | |
ATE460153T1 (de) | Riechstoffvorläufer | |
Mary et al. | Modulation of T cell activation by differential regulation of the phosphorylation of two cytosolic proteins: implication of both Ca2+ and cyclic AMP-dependent protein kinases | |
WO2000002582A3 (fr) | Traitement de la maladie coeliaque a l'aide d'antagonistes de l'interleukine-15 | |
WO2002026781A3 (fr) | Antagonistes du recepteur d'ige | |
ATE222901T1 (de) | Carboxylsubstituierte chromanderivate zur verwendung als beta 3 adrenorezeptor-agonisten | |
NO20004801D0 (no) | Glidemiddel pÕ basis av oktadekan | |
WO2004008153A3 (fr) | Diagnostique et therapie des maladies associees au recepteur presume de neurotransmetteurs chez l'humain (pnr) | |
EP0922760A3 (fr) | Animal transgénique n' exprimant pas de facteur inhibant l'ostéoclastogenèse (OCIF) endogène | |
WO2004003507A3 (fr) | Procedes d'identification de composes regulant la masse ou la fonction musculaire au moyen de recepteurs de l'amyline | |
WO2007084648A3 (fr) | Dimères mixtes 4-6 procyanidine et leur utilisation |