ZA200109775B - Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions. - Google Patents

Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions. Download PDF

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Publication number
ZA200109775B
ZA200109775B ZA200109775A ZA200109775A ZA200109775B ZA 200109775 B ZA200109775 B ZA 200109775B ZA 200109775 A ZA200109775 A ZA 200109775A ZA 200109775 A ZA200109775 A ZA 200109775A ZA 200109775 B ZA200109775 B ZA 200109775B
Authority
ZA
South Africa
Prior art keywords
polymorphic form
crystalline
citrate monohydrate
hours
citrate
Prior art date
Application number
ZA200109775A
Other languages
English (en)
Inventor
Castaldi Michael James
Quallich George Joseph
Wint Lewin Theophilus
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200109775B publication Critical patent/ZA200109775B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200109775A 1999-06-01 2001-11-28 Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions. ZA200109775B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13699299P 1999-06-01 1999-06-01

Publications (1)

Publication Number Publication Date
ZA200109775B true ZA200109775B (en) 2002-11-28

Family

ID=22475338

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109775A ZA200109775B (en) 1999-06-01 2001-11-28 Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions.

Country Status (49)

Country Link
US (1) US6255320B1 (ja)
EP (1) EP1181290B1 (ja)
JP (1) JP3830816B2 (ja)
KR (1) KR100476606B1 (ja)
CN (1) CN1146565C (ja)
AP (1) AP2001002349A0 (ja)
AR (1) AR033331A1 (ja)
AT (1) ATE244239T1 (ja)
AU (1) AU767334B2 (ja)
BG (1) BG65240B1 (ja)
BR (1) BR0011094A (ja)
CA (1) CA2372238C (ja)
CO (1) CO5170463A1 (ja)
CY (1) CY2007011I2 (ja)
CZ (1) CZ295819B6 (ja)
DE (1) DE60003679T2 (ja)
DK (1) DK1181290T3 (ja)
DZ (1) DZ3050A1 (ja)
EA (1) EA003731B1 (ja)
EC (1) ECSP003508A (ja)
EE (1) EE200100656A (ja)
ES (1) ES2199825T3 (ja)
GT (1) GT200000087A (ja)
HK (1) HK1046284A1 (ja)
HN (1) HN2000000077A (ja)
HR (1) HRP20010904A2 (ja)
HU (1) HUP0201301A3 (ja)
IL (1) IL146406A0 (ja)
MA (1) MA26742A1 (ja)
MX (1) MXPA01012325A (ja)
MY (1) MY133508A (ja)
NO (1) NO20015848L (ja)
NZ (1) NZ515349A (ja)
OA (1) OA11956A (ja)
PA (1) PA8496101A1 (ja)
PE (1) PE20010209A1 (ja)
PL (1) PL196046B1 (ja)
PT (1) PT1181290E (ja)
SI (1) SI1181290T1 (ja)
SK (1) SK285820B6 (ja)
SV (1) SV2001000093A (ja)
TN (1) TNSN00120A1 (ja)
TR (1) TR200103473T2 (ja)
TW (1) TWI285204B (ja)
UA (1) UA66925C2 (ja)
UY (1) UY26176A1 (ja)
WO (1) WO2000073304A1 (ja)
YU (1) YU81101A (ja)
ZA (1) ZA200109775B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5021318B2 (ja) * 2004-01-30 2012-09-05 ファイザー・プロダクツ・インク β−シクロデキストリンを液体投薬形態に用いて多用量製剤を達成するための抗菌性防腐剤
JP2007519702A (ja) * 2004-01-30 2007-07-19 ファイザー・プロダクツ・インク ニューロキニン受容体拮抗薬及びシクロデキストリンからなる医薬組成物、ならびに注射部位の耐容性を改善するための方法
AU2005216706B2 (en) 2004-01-30 2007-11-29 Pfizer Products Inc. NK-1 receptor antagonists anesthesia recovery
CN1914202A (zh) * 2004-02-02 2007-02-14 辉瑞产品有限公司 1－(2s,3s)－2－二苯甲基－n－(5－叔丁基－2－甲氧基苄基)奎宁环－3－胺的制备方法
JP6454323B2 (ja) * 2013-03-15 2019-01-16 パール セラピューティクス，インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム
CN110577522B (zh) * 2018-06-07 2022-12-27 东莞市东阳光动物保健药品有限公司 马罗匹坦柠檬酸盐新晶型及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9290063U1 (de) * 1991-05-31 1994-02-24 Pfizer Inc., New York, N.Y. Chinuclidin-Derivate
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
US5576317A (en) * 1994-12-09 1996-11-19 Pfizer Inc. NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis

Also Published As

Publication number Publication date
SK17332001A3 (sk) 2002-07-02
GT200000087A (es) 2001-11-22
NO20015848L (no) 2001-12-18
US6255320B1 (en) 2001-07-03
PA8496101A1 (es) 2002-07-30
DE60003679T2 (de) 2004-05-27
MXPA01012325A (es) 2002-07-22
SK285820B6 (sk) 2007-09-06
JP3830816B2 (ja) 2006-10-11
CY2007011I1 (el) 2010-07-28
MA26742A1 (fr) 2004-12-20
HRP20010904A2 (en) 2003-02-28
KR100476606B1 (ko) 2005-03-18
DE60003679D1 (de) 2003-08-07
PE20010209A1 (es) 2001-03-01
CA2372238C (en) 2006-12-19
AR033331A1 (es) 2003-12-17
PL196046B1 (pl) 2007-11-30
PL352716A1 (en) 2003-09-08
OA11956A (en) 2006-04-13
ES2199825T3 (es) 2004-03-01
PT1181290E (pt) 2003-09-30
CN1146565C (zh) 2004-04-21
UA66925C2 (uk) 2004-06-15
DK1181290T3 (da) 2003-09-29
HUP0201301A3 (en) 2002-10-28
EA200101108A1 (ru) 2002-04-25
EP1181290B1 (en) 2003-07-02
DZ3050A1 (fr) 2004-03-27
BG106204A (en) 2002-07-31
MY133508A (en) 2007-11-30
ATE244239T1 (de) 2003-07-15
CO5170463A1 (es) 2002-06-27
CZ20014269A3 (cs) 2002-04-17
TNSN00120A1 (fr) 2005-11-10
HK1046284A1 (en) 2003-01-03
IL146406A0 (en) 2002-07-25
BG65240B1 (bg) 2007-09-28
CZ295819B6 (cs) 2005-11-16
EA003731B1 (ru) 2003-08-28
HUP0201301A2 (en) 2002-08-28
AP2001002349A0 (en) 2001-12-31
BR0011094A (pt) 2002-03-19
UY26176A1 (es) 2000-12-29
SI1181290T1 (en) 2003-12-31
TR200103473T2 (tr) 2002-04-22
TWI285204B (en) 2007-08-11
ECSP003508A (es) 2002-02-25
AU4424800A (en) 2000-12-18
CY2007011I2 (el) 2010-07-28
JP2003501354A (ja) 2003-01-14
EE200100656A (et) 2003-02-17
NZ515349A (en) 2004-03-26
AU767334B2 (en) 2003-11-06
EP1181290A1 (en) 2002-02-27
SV2001000093A (es) 2001-11-08
NO20015848D0 (no) 2001-11-30
HN2000000077A (es) 2001-02-02
KR20020010688A (ko) 2002-02-04
CA2372238A1 (en) 2000-12-07
YU81101A (sh) 2004-07-15
WO2000073304A1 (en) 2000-12-07
CN1353711A (zh) 2002-06-12

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