ZA200005445B - Improved immunodiagnostic assays using reducing agents. - Google Patents
Improved immunodiagnostic assays using reducing agents. Download PDFInfo
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- ZA200005445B ZA200005445B ZA200005445A ZA200005445A ZA200005445B ZA 200005445 B ZA200005445 B ZA 200005445B ZA 200005445 A ZA200005445 A ZA 200005445A ZA 200005445 A ZA200005445 A ZA 200005445A ZA 200005445 B ZA200005445 B ZA 200005445B
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- Prior art keywords
- hcv
- reducing agent
- solid phase
- protein
- polypeptide
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Classifications
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/54306—Solid-phase reaction mechanisms
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
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- G—PHYSICS
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- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| EP98870087 | 1998-04-17 |
Publications (1)
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| ZA200005445B true ZA200005445B (en) | 2003-01-06 |
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| ZA200005445A ZA200005445B (en) | 1998-04-17 | 2000-10-05 | Improved immunodiagnostic assays using reducing agents. |
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| EP (2) | EP1071955B2 (es) |
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| AU (1) | AU751362B2 (es) |
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| CA (2) | CA2324970C (es) |
| CY (1) | CY1108424T1 (es) |
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| HU (1) | HUP0101719A3 (es) |
| IL (1) | IL138791A0 (es) |
| PL (1) | PL343469A1 (es) |
| PT (2) | PT1071955E (es) |
| TR (4) | TR200003024T2 (es) |
| WO (1) | WO1999054735A1 (es) |
| ZA (1) | ZA200005445B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2002518037A (ja) * | 1998-06-24 | 2002-06-25 | イノジェネティックス・ナムローゼ・フェンノートシャップ | Ｈｃｖエンベロープ蛋白の粒子：ワクチン接種への使用 |
| ATE375804T1 (de) * | 2000-08-17 | 2007-11-15 | Tripep Ab | Ribavirin-enthaltende vakzine |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| HUP0303924A2 (hu) * | 2001-04-24 | 2004-03-01 | Innogenetics N.V. | Core-glikozilált HCV-burokproteinek |
| JP2004108914A (ja) * | 2002-09-18 | 2004-04-08 | Kudo Norio | コラーゲンの測定方法 |
| CA2504711A1 (en) * | 2002-11-08 | 2004-05-21 | Innogenetics N.V. | Hcv vaccine compositions comprising e1 and ns3 peptides |
| US20050014136A1 (en) * | 2003-05-28 | 2005-01-20 | Innogenetics N.V. | Modified HCV NS5 |
| KR20070108284A (ko) * | 2003-10-28 | 2007-11-08 | 가부시끼가이샤 센단세메이가가꾸겐큐죠 | Ｃ형 간염 바이러스의 검출 방법 |
| CA2657223A1 (en) * | 2006-07-07 | 2008-01-10 | Pall Corporation | Use of denaturing agents during affinity capture |
| JP2010533491A (ja) * | 2007-07-16 | 2010-10-28 | ファイザー・インク | 乳生産動物および乳業産物のゲノムマーカー指数を改善する方法 |
| BRPI0816776A2 (pt) * | 2007-09-12 | 2019-09-24 | Pfizer | métodos para usar marcadores genéticos e interações epistáticas relacionadas |
| JP2011501659A (ja) * | 2007-10-03 | 2011-01-13 | ファイザー・インク | 有角および無角ウシの遺伝子マーカーおよび関連する方法 |
| JP2011505872A (ja) * | 2007-12-17 | 2011-03-03 | ファイザー・インク | 乳用動物および乳用生産物の遺伝的プロフィールを改良する方法 |
| EP2318838B1 (en) * | 2008-07-16 | 2013-09-04 | Radiometer Medical ApS | High capacity solid phase |
| CN102081018A (zh) * | 2009-11-30 | 2011-06-01 | 希森美康株式会社 | 样品的预处理方法及hcv的免疫测定方法 |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
| CN107110868B (zh) | 2014-10-29 | 2020-08-21 | 雅培制药有限公司 | 采用ns3捕获肽的受试者抗hcv抗体检测测定 |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN109678954B (zh) * | 2018-12-29 | 2022-01-07 | 山东莱博生物科技有限公司 | 一对能够特异性识别hcv ns3蛋白的单克隆抗体及其应用 |
| CN110988362B (zh) * | 2019-12-20 | 2023-11-14 | 迈克生物股份有限公司 | 抗组蛋白抗体测定试剂、试剂盒及其使用方法 |
| CN112225783B (zh) * | 2020-09-16 | 2021-08-31 | 东莞市朋志生物科技有限公司 | Hcv重组抗原及其突变体 |
| CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
| CN113219169B (zh) * | 2021-05-22 | 2021-12-17 | 北京金诺百泰生物技术有限公司 | 生物检测用封闭剂及其制备方法、包被板及应用该包被板的试剂盒 |
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| EP0139526A2 (en) * | 1983-10-20 | 1985-05-02 | Warner-Lambert Company | An insolubilized stable specific binding protein |
| US4616078A (en) * | 1985-04-08 | 1986-10-07 | Eli Lilly And Company | Process for purifying proinsulin-like materials |
| CA1340877C (en) * | 1987-12-28 | 2000-01-18 | Takashi Sugiyama | Elastase inhibitory polypeptide and process for production thereof by recombinant gene technology |
| ATE92633T1 (de) * | 1988-05-11 | 1993-08-15 | Abbott Lab | Verfahren zur erhoehung der spezifizitaet in kompetitiven immuntests. |
| US4923967A (en) * | 1988-09-26 | 1990-05-08 | Eli Lilly And Company | Purification and refolding of recombinant proteins |
| CA2079105C (en) | 1990-04-04 | 2000-06-13 | Michael Houghton | Hepatitis c virus protease |
| US6194140B1 (en) * | 1990-04-04 | 2001-02-27 | Chiron Corporation | HCV NS3 protein fragments having helicase activity and improved solubility |
| US5606031A (en) * | 1990-04-06 | 1997-02-25 | Lile; Jack | Production and purification of biologically active recombinant neurotrophic protein in bacteria |
| RO117329B1 (ro) * | 1991-06-24 | 2002-01-30 | Chiron Corp Emeryville | Polipeptide care contin o secventa a virusului hepatitei c |
| JP3225468B2 (ja) | 1992-08-28 | 2001-11-05 | ダイナボット株式会社 | 抗体測定用試薬 |
| ATE552340T1 (de) | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln |
| ATE290592T1 (de) | 1993-11-04 | 2005-03-15 | Innogenetics Nv | Von menschlichen t-zellen immunodominante epitopen des virus der c-hepatitis |
| ATE208481T1 (de) | 1994-06-23 | 2001-11-15 | Energy Answers Corp | Anlage zur erzeugung von asche enthaltenden produkten und energie aus abfällen |
| EP1211315A1 (en) * | 1994-07-29 | 2002-06-05 | Innogenetics N.V. | Recombinant vectors for producing HCV envelope proteins |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| JPH0862219A (ja) | 1994-08-19 | 1996-03-08 | Dainabotsuto Kk | 還元型抗原に対する抗体アッセイ試薬及びそれを使用した測定方法 |
| BR9509421A (pt) | 1994-10-21 | 1997-09-30 | Innogenetics Nv | Novas sequências de genotipos de vírus de hepatite C e uso como agentes profiláticos terapêuticos e diagnósticos |
| US5705330A (en) * | 1995-04-14 | 1998-01-06 | Abbott Laboratories | Chemiluminescent immunoassay for antibody detection |
| US5616460A (en) * | 1995-06-07 | 1997-04-01 | Abbott Laboratories | Buffer composition for reagents for immunoassay |
| CA2250723C (en) | 1996-05-24 | 2012-07-17 | Chiron Corporation | Multiple epitope fusion protein |
| JP4163756B2 (ja) * | 1997-01-13 | 2008-10-08 | ローム アンド ハース エレクトロニック マテリアルズ シーエムピー ホウルディングス インコーポレイテッド | ホトリソグラフィーによって形成された表面パターンを有するポリマー研磨パッド及びこれに関する方法 |
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1999
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- 1999-04-15 PT PT04103238T patent/PT1471074E/pt unknown
- 1999-04-15 DE DE69939132T patent/DE69939132D1/de not_active Expired - Lifetime
- 1999-04-15 DE DE69920895T patent/DE69920895T3/de not_active Expired - Lifetime
- 1999-04-15 EP EP99920678A patent/EP1071955B2/en not_active Expired - Lifetime
- 1999-04-15 AT AT99920678T patent/ATE278960T1/de active
- 1999-04-15 DK DK04103238T patent/DK1471074T3/da active
- 1999-04-15 AU AU38171/99A patent/AU751362B2/en not_active Expired
- 1999-04-15 EP EP04103238A patent/EP1471074B1/en not_active Expired - Lifetime
- 1999-04-15 ES ES04103238T patent/ES2310701T3/es not_active Expired - Lifetime
- 1999-04-15 HU HU0101719A patent/HUP0101719A3/hu unknown
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2000
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2001
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2005
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2006
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2008
- 2008-10-16 CY CY20081101157T patent/CY1108424T1/el unknown
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