ATE552340T1 - Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln - Google Patents

Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln

Info

Publication number
ATE552340T1
ATE552340T1 AT99118785T AT99118785T ATE552340T1 AT E552340 T1 ATE552340 T1 AT E552340T1 AT 99118785 T AT99118785 T AT 99118785T AT 99118785 T AT99118785 T AT 99118785T AT E552340 T1 ATE552340 T1 AT E552340T1
Authority
AT
Austria
Prior art keywords
hepatitis
treatment
sequences
present
virus genotype
Prior art date
Application number
AT99118785T
Other languages
English (en)
Inventor
Geert Maertens
Lieven Stuyver
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Application granted granted Critical
Publication of ATE552340T1 publication Critical patent/ATE552340T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99118785T 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln ATE552340T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93401099 1993-04-27
EP93402019 1993-08-05

Publications (1)

Publication Number Publication Date
ATE552340T1 true ATE552340T1 (de) 2012-04-15

Family

ID=26134679

Family Applications (4)

Application Number Title Priority Date Filing Date
AT94915550T ATE373093T1 (de) 1993-04-27 1994-04-27 Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika
AT99118785T ATE552340T1 (de) 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln
AT99118784T ATE551423T1 (de) 1993-04-27 1994-04-27 Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika
AT99118783T ATE553201T1 (de) 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT94915550T ATE373093T1 (de) 1993-04-27 1994-04-27 Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT99118784T ATE551423T1 (de) 1993-04-27 1994-04-27 Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika
AT99118783T ATE553201T1 (de) 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel

Country Status (15)

Country Link
US (3) US6762024B2 (de)
EP (4) EP1004670B1 (de)
JP (5) JPH07508423A (de)
CN (1) CN1108030A (de)
AT (4) ATE373093T1 (de)
AU (1) AU688323B2 (de)
BR (1) BR9405334A (de)
CA (2) CA2139100C (de)
DE (1) DE69435023T2 (de)
ES (1) ES2294779T3 (de)
FI (1) FI946066A (de)
NO (1) NO944967L (de)
NZ (1) NZ266148A (de)
SG (1) SG50563A1 (de)
WO (1) WO1994025601A2 (de)

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US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
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US7255997B1 (en) * 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
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US6881821B2 (en) 1993-05-05 2005-04-19 Common Services Agency Hepatitis-C virus type 4, 5, and 6
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US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US7129337B1 (en) * 1994-10-21 2006-10-31 Innogenetics N.V. Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
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AU751362B2 (en) 1998-04-17 2002-08-15 Innogenetics N.V. Improved immunodiagnostic assays using reducing agents
WO1999055385A2 (de) * 1998-04-28 1999-11-04 Wolfgang Bergter Radioimmunpharmaka zur therapie der hepatitis c
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US7052830B1 (en) 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
BRPI0111731C1 (pt) 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
ATE375804T1 (de) * 2000-08-17 2007-11-15 Tripep Ab Ribavirin-enthaltende vakzine
US7196183B2 (en) * 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
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DK1490383T3 (da) * 2002-03-11 2009-06-08 Lab 21 Ltd Fremgangsmåde og sammensætning til identifikation og karakterisering af hepatitis C
EP1523557A2 (de) 2002-07-24 2005-04-20 Intercell AG Bei alternativen leserahmen kodiertete antigenen aus pathogenischen viren
EP2402026A3 (de) 2002-09-13 2012-04-18 Intercell AG Verfahren zum Isolieren von Hepatitis-C-Virus-Peptiden
WO2004084938A1 (en) 2003-03-24 2004-10-07 Intercell Ag Improved vaccines
PL1648502T3 (pl) 2003-07-11 2011-05-31 Intercell Ag Szczepionki przeciwko HCV
US8124747B2 (en) 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
CN1977050B (zh) * 2004-01-07 2012-09-05 第三次浪潮技术公司 丙型肝炎病毒基因型的确定
US20060162667A1 (en) * 2005-01-26 2006-07-27 Papadoyianis Ernest D Aquatic habitat and ecological tank
CA2618429A1 (en) * 2005-05-25 2007-03-22 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
US20070072211A1 (en) 2005-06-30 2007-03-29 Roche Molecular Systems, Inc. Asymmetric PCR coupled with post-PCR characterization for the identification of nucleic acids
MD3300G2 (ro) * 2006-09-28 2007-11-30 Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
WO2008046922A2 (en) * 2006-10-20 2008-04-24 Innogenetics N.V. Methodology for anaysis of sequence variations within the hcv ns5b genomic region
WO2008046923A2 (en) 2006-10-20 2008-04-24 Innogenetics N.V. Methodology for analysis of sequence variations within the hcv ns3/4a genomic region
EP2463389A1 (de) 2006-10-20 2012-06-13 Innogenetics N.V. Methodik zur Analyse von Sequenzvariationen innerhalb des HCV-NS5B-Genombereichs
US20100227314A1 (en) * 2007-08-09 2010-09-09 Dmitry Alexandrovich Gryadunov Method of identification of genotype and subtype of hepatitis c virus on a biological microchip
EP2185195A2 (de) * 2007-08-16 2010-05-19 Tripep Ab Immunogen-plattform
CN101842498A (zh) * 2007-10-30 2010-09-22 英特芒尼公司 Hcv基因型分型和表型分型
WO2009130588A2 (en) * 2008-04-22 2009-10-29 Tripep Ab Immunogen platform
WO2010112733A1 (fr) * 2009-03-30 2010-10-07 bioMérieux Support solide de détection du vhc
WO2013150450A1 (en) * 2012-04-02 2013-10-10 Universidade Do Porto Hcv homolog fragments, cell-lines and applications thereof
JP6859314B2 (ja) * 2015-03-27 2021-04-14 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． Ｈｃｖ ｎｓ４ａ／改変されたｎｓ３ポリペプチド及びその使用
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US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
JP2687852B2 (ja) * 1993-10-13 1997-12-08 日本電気株式会社 半導体メモリ装置

Also Published As

Publication number Publication date
CA2139100A1 (en) 1994-11-10
SG50563A1 (en) 1998-07-20
JP2002233388A (ja) 2002-08-20
US7195765B2 (en) 2007-03-27
CN1108030A (zh) 1995-09-06
AU688323B2 (en) 1998-03-12
EP0984067A2 (de) 2000-03-08
NZ266148A (en) 1997-06-24
US6762024B2 (en) 2004-07-13
FI946066A0 (fi) 1994-12-23
CA2662090A1 (en) 1994-11-10
JP2004041207A (ja) 2004-02-12
NO944967D0 (no) 1994-12-21
JPH07508423A (ja) 1995-09-21
ATE551423T1 (de) 2012-04-15
EP0651807A1 (de) 1995-05-10
US7157226B1 (en) 2007-01-02
EP1004670B1 (de) 2012-04-11
JP2004041206A (ja) 2004-02-12
CA2139100C (en) 2009-06-23
WO1994025601A3 (en) 1995-03-02
US20030008274A1 (en) 2003-01-09
EP0984067B1 (de) 2012-04-04
AU6722294A (en) 1994-11-21
DE69435023T2 (de) 2008-09-11
EP0651807B1 (de) 2007-09-12
DE69435023D1 (de) 2007-10-25
EP1004670A2 (de) 2000-05-31
EP0984068A2 (de) 2000-03-08
WO1994025601A2 (en) 1994-11-10
JP2002233389A (ja) 2002-08-20
US20030032005A1 (en) 2003-02-13
FI946066A (fi) 1994-12-23
EP0984068B1 (de) 2012-03-28
BR9405334A (pt) 1999-05-25
ATE373093T1 (de) 2007-09-15
ES2294779T3 (es) 2008-04-01
ATE553201T1 (de) 2012-04-15
NO944967L (no) 1994-12-21
EP1004670A3 (de) 2000-09-20
EP0984067A3 (de) 2000-09-27
EP0984068A3 (de) 2000-09-20

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