RU93058449A - Hcv геномные последовательности для диагностических и терапевтических целей - Google Patents
Hcv геномные последовательности для диагностических и терапевтических целейInfo
- Publication number
- RU93058449A RU93058449A RU93058449/14A RU93058449A RU93058449A RU 93058449 A RU93058449 A RU 93058449A RU 93058449/14 A RU93058449/14 A RU 93058449/14A RU 93058449 A RU93058449 A RU 93058449A RU 93058449 A RU93058449 A RU 93058449A
- Authority
- RU
- Russia
- Prior art keywords
- diagnostic
- therapeutic purposes
- genomic sequences
- hcv genomic
- hcv
- Prior art date
Links
- 230000001225 therapeutic Effects 0.000 title claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 241000711549 Hepacivirus C Species 0.000 claims 1
- 102000004965 antibodies Human genes 0.000 claims 1
- 108090001123 antibodies Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
Claims (1)
- В изобретении представлены композиции нуклеиновой кислоты, пептида и антитела, относящиеся к генотипам вируса гепатита С и к способам использования таких композиций для диагностических и терапевтических целей.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69732691A | 1991-05-08 | 1991-05-08 | |
US697,326 | 1991-05-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU93058449A true RU93058449A (ru) | 1996-11-10 |
RU2155228C2 RU2155228C2 (ru) | 2000-08-27 |
Family
ID=24800701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU93058449/13A RU2155228C2 (ru) | 1991-05-08 | 1992-05-08 | Hcv геномные последовательности для диагностических и терапевтических целей |
Country Status (20)
Country | Link |
---|---|
EP (2) | EP0585398B1 (ru) |
JP (7) | JPH06508026A (ru) |
KR (1) | KR100193801B1 (ru) |
AT (1) | ATE252154T1 (ru) |
BG (3) | BG62142B1 (ru) |
CA (1) | CA2108466C (ru) |
CZ (2) | CZ288720B6 (ru) |
DE (1) | DE69233234T2 (ru) |
DK (1) | DK0585398T3 (ru) |
ES (1) | ES2207633T3 (ru) |
FI (1) | FI115725B (ru) |
HU (1) | HU227548B1 (ru) |
IE (1) | IE921482A1 (ru) |
NO (1) | NO309532B1 (ru) |
PL (2) | PL169880B1 (ru) |
PT (1) | PT100472B (ru) |
RO (1) | RO117267B1 (ru) |
RU (1) | RU2155228C2 (ru) |
SK (1) | SK284205B6 (ru) |
WO (1) | WO1992019743A2 (ru) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5428145A (en) * | 1991-08-09 | 1995-06-27 | Immuno Japan, Inc. | Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
EP0532167A3 (en) * | 1991-08-09 | 1993-03-31 | Immuno Japan Inc. | Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
EP0532258A2 (en) * | 1991-09-09 | 1993-03-17 | Immuno Japan Inc. | Oligonucleotides and determination system of HCV genotypes |
US5763159A (en) | 1991-11-21 | 1998-06-09 | Common Services Agency | Hepatitis-C virus testing |
US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
EP1262560A2 (en) * | 1992-05-29 | 2002-12-04 | Abbott Laboratories | Method of forming cDNA from an RNA target sequence present in a sample |
NZ286209A (en) * | 1992-09-10 | 2000-09-29 | Isis Pharmaceuticals Inc | Use of HCV RNA anti-sense nucleotide sequences for treating Hepatitis C virus related disease |
US6423489B1 (en) * | 1992-09-10 | 2002-07-23 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of Hepatitis C virus-associated diseases |
US5846704A (en) | 1992-11-27 | 1998-12-08 | N.V. Innogenetics S.A. | Process for typing of HCV isolates |
JPH06153961A (ja) * | 1992-11-27 | 1994-06-03 | Imuno Japan:Kk | C型肝炎ウイルス部分遺伝子、ならびにc型肝炎ウイルス遺 伝子の高感度検出法 |
US7258977B1 (en) | 1992-11-27 | 2007-08-21 | Innogenetics N.V. | Process for typing of HCV isolates |
US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
US6762024B2 (en) | 1993-04-27 | 2004-07-13 | Innogenetics, S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
JPH0775585A (ja) * | 1993-06-14 | 1995-03-20 | Immuno Japan:Kk | C型肝炎ウイルス関連オリゴヌクレオチドならびにc型肝炎 ウイルス遺伝子型判定方法 |
US7070790B1 (en) | 1993-06-29 | 2006-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
US5882852A (en) * | 1993-06-29 | 1999-03-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates |
US5514539A (en) | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
WO1995011918A1 (fr) * | 1993-10-29 | 1995-05-04 | Srl, Inc. | Compose peptidique antigenique et methode de dosage immunologique |
EP0759979A4 (en) * | 1994-05-10 | 1999-10-20 | Gen Hospital Corp | ANTISENSE OLIGONUCLEOTIDES INHIBITION OF HEPATITIS C VIRUS |
ES2176342T5 (es) | 1994-10-21 | 2010-02-09 | Innogenetics N.V. | Secuencias del genotipo 7 del virus de la hepatitis c y su utilizacion como agentes profilacticos, terapeuticos y de diagnosticos. |
US5851759A (en) * | 1996-04-19 | 1998-12-22 | Chiron Corporation | Heteroduplex tracking assay (HTA) for genotyping HCV |
IT1284847B1 (it) * | 1996-06-07 | 1998-05-22 | Sorin Biomedica Diagnostics Sp | Procedimento per la rivelazione di acidi nucleici specifici di hcv |
CA2308368C (en) | 1997-11-04 | 2009-01-20 | Roche Diagnostics Gmbh | Specific and sensitive nucleic acid detection method |
US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
KR20070114209A (ko) | 2000-08-17 | 2007-11-29 | 트리펩 아베 | 리바비린 함유 백신 및 이것의 사용 방법 |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
US6586584B2 (en) | 2001-01-29 | 2003-07-01 | Becton, Dickinson And Company | Sequences and methods for detection of Hepatitis C virus |
US7196183B2 (en) | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
US8124747B2 (en) | 2003-08-29 | 2012-02-28 | Innogenetics | HCV clade and prototype sequences thereof |
WO2005067643A2 (en) | 2004-01-07 | 2005-07-28 | Third Wave Technologies, Inc. | Determination of hepatitis c virus genotype |
KR100733186B1 (ko) * | 2005-05-31 | 2007-06-27 | 재단법인 목암생명공학연구소 | Hcv 유전자에 특이적인 작은 간섭 rna 및 그를유효성분으로 포함하는 c형 간염 치료제 |
EP2185195A2 (en) | 2007-08-16 | 2010-05-19 | Tripep Ab | Immunogen platform |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR8807310A (pt) * | 1987-11-18 | 1990-03-13 | Chiron Corp | Polinucleotidio,polinucleotidio recombinante,vetor recombinante,celula hospedeira,sistema de expressao recombinante,celula transformada,polipeptidio,hcv,preparacao de polipeptidio,polipeptidio de hcv,polipeptidio purificado,polipeptidio recombinante,polipeptidio de fusao,anticorpo monoclonal,preparacao purificada de anticorpos policlonais,particula,sonda de polinucleotidio,kit anticorpo para epetopo de hcv,metodo para producao de polipeptidio,metodo para deteccao de acidos nucleicos de hcv,imunoensaio para detectar antigeno de hcv,imunoensaio para detectar anticorpos dirigidos contra antigeno de hcv,vacina para tratamento de infeccao de hcv,celula,celula infectada com hcv,metodo para producao de anticorpos para hcv e metodo para isolar cdna derivado do genoma de um agente infeccioso nao identificado |
UA50829C2 (ru) * | 1989-03-17 | 2002-11-15 | Чірон Корпорейшн | Полинуклеотид, вектор, клетки, система экспрессии, полипептиды, моноклональные антитела, препарат поликлональных антител, нуклеотидная проба, аналитические наборы, способ выявления нуклеиновых кислот, способы иммуноанализа, вакцина, способ получения антител |
GB2239245B (en) * | 1989-12-18 | 1993-11-10 | Wellcome Found | Post-transfusional non-A non-B hepatitis viral polypeptides |
WO1991014779A1 (en) * | 1990-03-28 | 1991-10-03 | Mitsui Toatsu Chemicals, Incorporated | Diagnostic for hepatitis virus |
JPH05506230A (ja) * | 1990-04-06 | 1993-09-16 | ジーンラブス テクノロジイズ インコーポレイテッド | C型肝炎ウイルスエピトープ |
EP0933426A1 (en) * | 1990-06-25 | 1999-08-04 | The Research Foundation for Microbial Diseases of Osaka University | Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides |
AU652941B2 (en) * | 1990-06-25 | 1994-09-15 | Research Foundation For Microbial Diseases Of Osaka University, The | Non-A, Non-B hepatitis virus particles |
EP0510952A1 (en) * | 1991-04-26 | 1992-10-28 | Immuno Japan Inc. | Oligonucleotide primers and their application for high-fidelity detection of non-a, non-b hepatitis virus |
-
1992
- 1992-05-08 DK DK92913881T patent/DK0585398T3/da active
- 1992-05-08 WO PCT/US1992/004036 patent/WO1992019743A2/en not_active Application Discontinuation
- 1992-05-08 PL PL92301282A patent/PL169880B1/pl unknown
- 1992-05-08 AT AT92913881T patent/ATE252154T1/de not_active IP Right Cessation
- 1992-05-08 SK SK1232-93A patent/SK284205B6/sk not_active IP Right Cessation
- 1992-05-08 KR KR1019930703367A patent/KR100193801B1/ko not_active IP Right Cessation
- 1992-05-08 HU HU9303166A patent/HU227548B1/hu unknown
- 1992-05-08 ES ES92913881T patent/ES2207633T3/es not_active Expired - Lifetime
- 1992-05-08 EP EP92913881A patent/EP0585398B1/en not_active Revoked
- 1992-05-08 JP JP4512055A patent/JPH06508026A/ja not_active Withdrawn
- 1992-05-08 EP EP03013389A patent/EP1394256A3/en not_active Withdrawn
- 1992-05-08 PL PL92312096A patent/PL170151B1/pl unknown
- 1992-05-08 RU RU93058449/13A patent/RU2155228C2/ru active
- 1992-05-08 CZ CZ19932377A patent/CZ288720B6/cs not_active IP Right Cessation
- 1992-05-08 CA CA002108466A patent/CA2108466C/en not_active Expired - Lifetime
- 1992-05-08 DE DE69233234T patent/DE69233234T2/de not_active Revoked
- 1992-05-08 PT PT100472A patent/PT100472B/pt not_active IP Right Cessation
- 1992-05-08 CZ CZ19961210A patent/CZ288722B6/cs not_active IP Right Cessation
- 1992-05-08 RO RO93-01493A patent/RO117267B1/ro unknown
- 1992-07-01 IE IE148292A patent/IE921482A1/en not_active IP Right Cessation
-
1993
- 1993-11-05 NO NO934019A patent/NO309532B1/no not_active IP Right Cessation
- 1993-11-05 BG BG98200A patent/BG62142B1/bg unknown
- 1993-11-05 BG BG101876A patent/BG64627B1/bg unknown
- 1993-11-08 FI FI934937A patent/FI115725B/fi not_active IP Right Cessation
-
1997
- 1997-09-04 BG BG101876A patent/BG101876A/xx unknown
-
2002
- 2002-05-10 JP JP2002134997A patent/JP2003009891A/ja not_active Withdrawn
- 2002-05-10 JP JP2002134999A patent/JP2003009892A/ja not_active Withdrawn
- 2002-05-10 JP JP2002134998A patent/JP2003024090A/ja not_active Withdrawn
- 2002-05-10 JP JP2002135000A patent/JP2003009893A/ja not_active Withdrawn
-
2004
- 2004-06-04 JP JP2004167859A patent/JP2004290204A/ja not_active Withdrawn
-
2008
- 2008-03-05 JP JP2008055639A patent/JP2008178416A/ja active Pending
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