DE69435023D1 - Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika - Google Patents

Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika

Info

Publication number
DE69435023D1
DE69435023D1 DE69435023T DE69435023T DE69435023D1 DE 69435023 D1 DE69435023 D1 DE 69435023D1 DE 69435023 T DE69435023 T DE 69435023T DE 69435023 T DE69435023 T DE 69435023T DE 69435023 D1 DE69435023 D1 DE 69435023D1
Authority
DE
Germany
Prior art keywords
sequences
present
genotype
medicaments
diagnostics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69435023T
Other languages
English (en)
Other versions
DE69435023T2 (de
Inventor
Geert Maertens
Lieven Stuyver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Application granted granted Critical
Publication of DE69435023D1 publication Critical patent/DE69435023D1/de
Publication of DE69435023T2 publication Critical patent/DE69435023T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69435023T 1993-04-27 1994-04-27 Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimittel und diagnostika Expired - Lifetime DE69435023T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP93401099 1993-04-27
EP93401099 1993-04-27
EP93402019 1993-08-05
EP93402019 1993-08-05
PCT/EP1994/001323 WO1994025601A2 (en) 1993-04-27 1994-04-27 New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents

Publications (2)

Publication Number Publication Date
DE69435023D1 true DE69435023D1 (de) 2007-10-25
DE69435023T2 DE69435023T2 (de) 2008-09-11

Family

ID=26134679

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69435023T Expired - Lifetime DE69435023T2 (de) 1993-04-27 1994-04-27 Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimittel und diagnostika

Country Status (15)

Country Link
US (3) US6762024B2 (de)
EP (4) EP0984067B1 (de)
JP (5) JPH07508423A (de)
CN (1) CN1108030A (de)
AT (4) ATE553201T1 (de)
AU (1) AU688323B2 (de)
BR (1) BR9405334A (de)
CA (2) CA2139100C (de)
DE (1) DE69435023T2 (de)
ES (1) ES2294779T3 (de)
FI (1) FI946066A0 (de)
NO (1) NO944967D0 (de)
NZ (1) NZ266148A (de)
SG (1) SG50563A1 (de)
WO (1) WO1994025601A2 (de)

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US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
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US7255997B1 (en) * 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
JP3751315B2 (ja) 1993-05-05 2006-03-01 コモン サーヴィシス エージェンシー C型肝炎ウイルス4、5及び6型
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US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
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US7052830B1 (en) 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
EP1113777B1 (de) * 1998-06-09 2007-01-10 Andrea D. Branch Neues hepatitis c viruspeptid und seine verwendung
ATE348337T1 (de) * 2000-06-15 2007-01-15 Novartis Vaccines & Diagnostic Hcv-antigen/antikörper-kombinations-assay
US6858590B2 (en) * 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
ATE517184T1 (de) * 2000-08-17 2011-08-15 Tripep Ab Hcv ns3/4a kodierende nukleinsäure
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US7196183B2 (en) * 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
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AU2003218111B8 (en) * 2002-03-11 2008-11-20 Lab 21 Limited Methods and compositions for identifying and characterizing hepatitis C
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US8124747B2 (en) * 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
US7473773B2 (en) 2004-01-07 2009-01-06 Third Wave Technologies, Inc. Determination of hepatitis C virus genotype
US20060162667A1 (en) * 2005-01-26 2006-07-27 Papadoyianis Ernest D Aquatic habitat and ecological tank
EP1888751A2 (de) * 2005-05-25 2008-02-20 Tripep Ab Nichtstrukturelles ns3/4a-fusionsgen des hepatitis-c-virus
US7465561B2 (en) 2005-06-30 2008-12-16 Roche Molecular Systems, Inc. Probes and methods for hepatitis C virus typing using single probe analysis
MD3300G2 (ro) * 2006-09-28 2007-11-30 Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
US20090325145A1 (en) 2006-10-20 2009-12-31 Erwin Sablon Methodology for analysis of sequence variations within the hcv ns5b genomic region
EP2527474A1 (de) 2006-10-20 2012-11-28 Innogenetics N.V. Verfahren zur Analyse von Sequenzvariationen innerhalb des HCV-NS3/4A-Genombereichs
EP2121990A2 (de) * 2006-10-20 2009-11-25 Innogenetics N.V. Methodik zur analyse von sequenzvariationen innerhalb des hcv-ns5b-genombereichs
EP2236624B1 (de) * 2007-08-09 2012-11-07 Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Molekulyarnoi Biologi Im. V.A. Engelgardta Rossiiskoi Akademii Nauk Verfahren zur identifizierung des genotyps und subtyps von hepatitis-c-virus auf einem biologischen mikrochip
EP2185195A2 (de) * 2007-08-16 2010-05-19 Tripep Ab Immunogen-plattform
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WO2013150450A1 (en) * 2012-04-02 2013-10-10 Universidade Do Porto Hcv homolog fragments, cell-lines and applications thereof
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US5882852A (en) 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
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Also Published As

Publication number Publication date
CA2662090A1 (en) 1994-11-10
EP0984067A3 (de) 2000-09-27
EP0984068A2 (de) 2000-03-08
EP1004670B1 (de) 2012-04-11
CA2139100A1 (en) 1994-11-10
CA2139100C (en) 2009-06-23
WO1994025601A3 (en) 1995-03-02
US20030008274A1 (en) 2003-01-09
JP2004041207A (ja) 2004-02-12
ATE553201T1 (de) 2012-04-15
AU688323B2 (en) 1998-03-12
US6762024B2 (en) 2004-07-13
EP0984068A3 (de) 2000-09-20
NO944967L (no) 1994-12-21
BR9405334A (pt) 1999-05-25
FI946066A (fi) 1994-12-23
EP1004670A3 (de) 2000-09-20
ATE373093T1 (de) 2007-09-15
NO944967D0 (no) 1994-12-21
EP0984067A2 (de) 2000-03-08
EP0651807B1 (de) 2007-09-12
WO1994025601A2 (en) 1994-11-10
EP1004670A2 (de) 2000-05-31
EP0984068B1 (de) 2012-03-28
EP0984067B1 (de) 2012-04-04
US7157226B1 (en) 2007-01-02
ES2294779T3 (es) 2008-04-01
AU6722294A (en) 1994-11-21
JPH07508423A (ja) 1995-09-21
EP0651807A1 (de) 1995-05-10
DE69435023T2 (de) 2008-09-11
FI946066A0 (fi) 1994-12-23
SG50563A1 (en) 1998-07-20
JP2002233388A (ja) 2002-08-20
US20030032005A1 (en) 2003-02-13
NZ266148A (en) 1997-06-24
ATE552340T1 (de) 2012-04-15
JP2004041206A (ja) 2004-02-12
US7195765B2 (en) 2007-03-27
ATE551423T1 (de) 2012-04-15
JP2002233389A (ja) 2002-08-20
CN1108030A (zh) 1995-09-06

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