YU48255B - Racemski ili optički aktivni izohinolin derivati, postupak za njihovo dobivanje i postupak za dobivanje farmaceutskih preparata koji ih sadrže - Google Patents

Racemski ili optički aktivni izohinolin derivati, postupak za njihovo dobivanje i postupak za dobivanje farmaceutskih preparata koji ih sadrže

Info

Publication number
YU48255B
YU48255B YU179991A YU179991A YU48255B YU 48255 B YU48255 B YU 48255B YU 179991 A YU179991 A YU 179991A YU 179991 A YU179991 A YU 179991A YU 48255 B YU48255 B YU 48255B
Authority
YU
Yugoslavia
Prior art keywords
group
normal
branched chain
preparation
procedure
Prior art date
Application number
YU179991A
Other languages
English (en)
Other versions
YU179991A (sh
Inventor
K. Takacs
I. Kiss
I. Hermecz
J. Ori
M. Pap
Z. Bencze
Koroczy P. Szekely
M. Szabo
J. SZEREDY nee VARGA
C. Vertesi
L. Debreczeni
J. Gaal
Z. Kapui
Original Assignee
Chinoin Gyogyszer Es Vegieszeti Termekek Gyara Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegieszeti Termekek Gyara Rt. filed Critical Chinoin Gyogyszer Es Vegieszeti Termekek Gyara Rt.
Priority to SI9111799A priority Critical patent/SI9111799A/sl
Priority to HRP920569 priority patent/HRP920569A2/hr
Publication of YU179991A publication Critical patent/YU179991A/sh
Publication of YU48255B publication Critical patent/YU48255B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

RACEMSKI ILI OPTIČKI AKTIVNI IZOHINOLIN DERIVATI, POSTUPAK ZA NJIHOVO DOBIVANJE I POSTUPAK ZA DOBIVANJE FARMACEUTSKIH PREPARATA KOJI IH SADRŽE - Racemski ili optički aktivni izohinolin derivati opšte formule (I) gde R označava vodonik ili C1-6alkoksi grupu normalnog ili račvastog lanca; R1 označava vodonik ili C1-6alkil grupu normalnog ili račvastog lanca; R2 predstavlja vodonik ili C1-6alkil grupu normalnog ili račvastog lanca; R3 označava vodonik, C1-6alkil grupu normalnog ili račvastog lanca po izboru supstituisanu sa 1 ili 2 hidroksilne grupe i/ili 1 ili 2 C1-4alkoksi grupa normalnog ili račvastog lanca; ili C4-7cikloalkil grupu; R4 označava vodonik ili C1-6alkil grupu normalnog ili račvas-tog lanca po izboru supstituisanu sa 1 ili 2 hidroksilne i/ili 1 ili 2 C1-4alkoksi grupa normalnog ili račvastog lanca; ili C4-7cikloalkil grupu ili R3 i R4 zajedno sa atomom azota na koji su vezani grade 4-8 -članu cikličnu grupu formule po izboru supstituisanu sa 1 ili 2 C1-4alkoksi grupe normalnog ili račvastog lanca i/ili 1 ili 2 C1-4alkil grupa normalnog ili račvastog lanca, gde po izboru atom kiseonika ili sumpora ili N-R5 grupa može biti supstituisan za prstenski atom ugljenika, gde R5 označava vodonik ili C1-6alifatična alkil grupa normal-nog ili račvastog lanca, 4-8-člani cikl po izboru je kondenzovan sa benzenskim prsteom; R6 označava vodonik ili C1-10acil grupu, i njihove soli kao i hidrati slobodnih jedinjenja opšte formule (I) i njihovih soli. - Prijava sadrži još 2 nezavisna i 31 zavisan zahtev.
YU179991A 1990-11-14 1991-11-14 Racemski ili optički aktivni izohinolin derivati, postupak za njihovo dobivanje i postupak za dobivanje farmaceutskih preparata koji ih sadrže YU48255B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI9111799A SI9111799A (sl) 1990-11-14 1991-11-14 Novi izokinolinski derivati, farmacevtski pripravki, ki jih vsebujejo in postopek za njihovo pridobivanje
HRP920569 HRP920569A2 (en) 1991-11-14 1992-09-28 Novel compounds, pharmaceutical compositions containing them and the process for preparing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU907125A HU209930B (en) 1990-11-14 1990-11-14 Process for producing of 2-mercapto-2-(1-isoquinolylidene)-acetonitrile derivatives and pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
YU179991A YU179991A (sh) 1994-06-10
YU48255B true YU48255B (sh) 1997-09-30

Family

ID=10972178

Family Applications (1)

Application Number Title Priority Date Filing Date
YU179991A YU48255B (sh) 1990-11-14 1991-11-14 Racemski ili optički aktivni izohinolin derivati, postupak za njihovo dobivanje i postupak za dobivanje farmaceutskih preparata koji ih sadrže

Country Status (26)

Country Link
US (1) US5179089A (sh)
EP (1) EP0486211A1 (sh)
JP (1) JPH0772178B2 (sh)
KR (1) KR950011412B1 (sh)
CN (1) CN1061409A (sh)
AR (1) AR248272A1 (sh)
AU (1) AU637010B2 (sh)
BG (1) BG60584B1 (sh)
CA (1) CA2055225A1 (sh)
CZ (1) CZ280715B6 (sh)
EE (1) EE02961B1 (sh)
FI (1) FI96417C (sh)
HU (1) HU209930B (sh)
IE (1) IE913777A1 (sh)
IL (1) IL99900A (sh)
MY (1) MY107827A (sh)
NO (1) NO179041C (sh)
NZ (1) NZ240581A (sh)
PL (1) PL166695B1 (sh)
PT (1) PT99485B (sh)
RO (1) RO112614B1 (sh)
RU (1) RU2090559C1 (sh)
SK (1) SK278791B6 (sh)
TW (1) TW202435B (sh)
YU (1) YU48255B (sh)
ZA (1) ZA918644B (sh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281248B1 (en) 2000-02-16 2001-08-28 Magda Abdel Fattah Ahmed Composition for treating asthma
HUP0000920A3 (en) * 2000-02-28 2002-03-28 Sanofi Synthelabo Pde4 inhibitor isoquinolinylidene derivatives, process for their preparation and medicaments containing them
HUP0000919A3 (en) * 2000-02-28 2002-03-28 Sanofi Synthelabo Pde4 inhibitor isoquinolinydene-derivatives, process for their preparation and medicaments containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178454B (en) * 1979-07-02 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new isoquinoline derivatives containing sulphur

Also Published As

Publication number Publication date
AU8777391A (en) 1992-05-21
KR950011412B1 (ko) 1995-10-04
CN1061409A (zh) 1992-05-27
US5179089A (en) 1993-01-12
FI96417C (fi) 1996-06-25
RO112614B1 (ro) 1997-11-28
IL99900A (en) 1995-07-31
PL292371A1 (en) 1992-11-02
NO914452D0 (no) 1991-11-13
CA2055225A1 (en) 1992-05-15
MY107827A (en) 1996-06-29
HU209930B (en) 1994-12-28
FI915354A0 (fi) 1991-11-13
CZ280715B6 (cs) 1996-04-17
PL166695B1 (pl) 1995-06-30
KR920009801A (ko) 1992-06-25
IL99900A0 (en) 1992-08-18
BG95460A (bg) 1993-12-24
TW202435B (sh) 1993-03-21
RU2090559C1 (ru) 1997-09-20
EE02961B1 (et) 1997-02-17
PT99485B (pt) 1999-04-30
NO179041B (no) 1996-04-15
BG60584B1 (bg) 1995-09-29
NO179041C (no) 1996-07-24
IE913777A1 (en) 1992-05-20
YU179991A (sh) 1994-06-10
AU637010B2 (en) 1993-05-13
JPH0772178B2 (ja) 1995-08-02
SK278791B6 (sk) 1998-03-04
EP0486211A1 (en) 1992-05-20
HUT62271A (en) 1993-04-28
HU907125D0 (en) 1991-05-28
JPH04283567A (ja) 1992-10-08
FI96417B (fi) 1996-03-15
AR248272A1 (es) 1995-07-12
NO914452L (no) 1992-05-15
FI915354A (fi) 1992-05-15
NZ240581A (en) 1994-05-26
CS344191A3 (en) 1992-06-17
PT99485A (pt) 1992-09-30
ZA918644B (en) 1992-10-28

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