BG95460A - Изохинолинови производни - Google Patents

Изохинолинови производни

Info

Publication number
BG95460A
BG95460A BG095460A BG9546091A BG95460A BG 95460 A BG95460 A BG 95460A BG 095460 A BG095460 A BG 095460A BG 9546091 A BG9546091 A BG 9546091A BG 95460 A BG95460 A BG 95460A
Authority
BG
Bulgaria
Prior art keywords
isoquinoline derivatives
well
allergic
bronchodilators
acetylcholine
Prior art date
Application number
BG095460A
Other languages
English (en)
Other versions
BG60584B1 (bg
Inventor
Kalman Takacs
Ilona Kiss
Istvan Hermecs
Janos Ori
Maria Pap
Zsolt Bencze
Peter Szekely
Maria Szabo
Judit Szeredy
Csaba Vertesi
Lorand Debreczeni
Jozsef Gaal
Zoltan Kapui
Original Assignee
Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. filed Critical Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
Publication of BG95460A publication Critical patent/BG95460A/bg
Publication of BG60584B1 publication Critical patent/BG60584B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Изобретението се отнася до изохинолинови производни с обща формула до солите и хидратите им, както и до фармацевтични състави, които ги съдържат. Съединенията са антагонистични към хистамин, ацетилхолин или серотонин, имат антиалергична активност и проявяват противовъзпалително действие. Поради това те могат да намерят приложение като бронходилататори, както и като антиалергични и противовъзпалителни лекарствени средства и по-специално при лечение на бронхиална астма. 35 претенции
BG95460A 1990-11-14 1991-11-13 Изохинолинови производни BG60584B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU907125A HU209930B (en) 1990-11-14 1990-11-14 Process for producing of 2-mercapto-2-(1-isoquinolylidene)-acetonitrile derivatives and pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
BG95460A true BG95460A (bg) 1993-12-24
BG60584B1 BG60584B1 (bg) 1995-09-29

Family

ID=10972178

Family Applications (1)

Application Number Title Priority Date Filing Date
BG95460A BG60584B1 (bg) 1990-11-14 1991-11-13 Изохинолинови производни

Country Status (26)

Country Link
US (1) US5179089A (bg)
EP (1) EP0486211A1 (bg)
JP (1) JPH0772178B2 (bg)
KR (1) KR950011412B1 (bg)
CN (1) CN1061409A (bg)
AR (1) AR248272A1 (bg)
AU (1) AU637010B2 (bg)
BG (1) BG60584B1 (bg)
CA (1) CA2055225A1 (bg)
CZ (1) CZ280715B6 (bg)
EE (1) EE02961B1 (bg)
FI (1) FI96417C (bg)
HU (1) HU209930B (bg)
IE (1) IE913777A1 (bg)
IL (1) IL99900A (bg)
MY (1) MY107827A (bg)
NO (1) NO179041C (bg)
NZ (1) NZ240581A (bg)
PL (1) PL166695B1 (bg)
PT (1) PT99485B (bg)
RO (1) RO112614B1 (bg)
RU (1) RU2090559C1 (bg)
SK (1) SK278791B6 (bg)
TW (1) TW202435B (bg)
YU (1) YU48255B (bg)
ZA (1) ZA918644B (bg)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281248B1 (en) 2000-02-16 2001-08-28 Magda Abdel Fattah Ahmed Composition for treating asthma
HUP0000919A3 (en) * 2000-02-28 2002-03-28 Sanofi Synthelabo Pde4 inhibitor isoquinolinydene-derivatives, process for their preparation and medicaments containing them
HUP0000920A3 (en) * 2000-02-28 2002-03-28 Sanofi Synthelabo Pde4 inhibitor isoquinolinylidene derivatives, process for their preparation and medicaments containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178454B (en) * 1979-07-02 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new isoquinoline derivatives containing sulphur

Also Published As

Publication number Publication date
KR920009801A (ko) 1992-06-25
YU179991A (sh) 1994-06-10
FI915354A (fi) 1992-05-15
FI96417B (fi) 1996-03-15
FI915354A0 (fi) 1991-11-13
HU907125D0 (en) 1991-05-28
HU209930B (en) 1994-12-28
NO179041B (no) 1996-04-15
US5179089A (en) 1993-01-12
NO179041C (no) 1996-07-24
IE913777A1 (en) 1992-05-20
IL99900A (en) 1995-07-31
CA2055225A1 (en) 1992-05-15
AU637010B2 (en) 1993-05-13
BG60584B1 (bg) 1995-09-29
EP0486211A1 (en) 1992-05-20
NO914452D0 (no) 1991-11-13
PT99485A (pt) 1992-09-30
RO112614B1 (ro) 1997-11-28
RU2090559C1 (ru) 1997-09-20
FI96417C (fi) 1996-06-25
PL166695B1 (pl) 1995-06-30
KR950011412B1 (ko) 1995-10-04
YU48255B (sh) 1997-09-30
IL99900A0 (en) 1992-08-18
AR248272A1 (es) 1995-07-12
CS344191A3 (en) 1992-06-17
CN1061409A (zh) 1992-05-27
PT99485B (pt) 1999-04-30
CZ280715B6 (cs) 1996-04-17
JPH04283567A (ja) 1992-10-08
EE02961B1 (et) 1997-02-17
SK278791B6 (sk) 1998-03-04
NO914452L (no) 1992-05-15
JPH0772178B2 (ja) 1995-08-02
PL292371A1 (en) 1992-11-02
ZA918644B (en) 1992-10-28
MY107827A (en) 1996-06-29
TW202435B (bg) 1993-03-21
AU8777391A (en) 1992-05-21
NZ240581A (en) 1994-05-26
HUT62271A (en) 1993-04-28

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