ES2082078T3 - 2-(4-piperidinil)-1h-pirido(4,3-b)indol-1-onas y compuestos relacionados, compuestos intermedios y procedimiento para su preparacion. - Google Patents

2-(4-piperidinil)-1h-pirido(4,3-b)indol-1-onas y compuestos relacionados, compuestos intermedios y procedimiento para su preparacion.

Info

Publication number
ES2082078T3
ES2082078T3 ES91116337T ES91116337T ES2082078T3 ES 2082078 T3 ES2082078 T3 ES 2082078T3 ES 91116337 T ES91116337 T ES 91116337T ES 91116337 T ES91116337 T ES 91116337T ES 2082078 T3 ES2082078 T3 ES 2082078T3
Authority
ES
Spain
Prior art keywords
pirido
indol
piperidinyl
compounds
onas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91116337T
Other languages
English (en)
Inventor
Lawrence Leo Martin
Denise M Flanagan
Joseph Francis Payack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2082078T3 publication Critical patent/ES2082078T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

LA PRESENTE APLICACION SE REFIERE A NUEVOS 2-(4-PIPERIDINIL) -1H-PIRIDO[4, 3-B]INDOL DE LA FORMULA EN LA QUE R ELEVADO 1 ES HIDROGENO, OPCIONALMENTE FENIL O FENIALQUILO SUBSTITUIDO, R (AL CUADRADO) ES HIDROGENO, ALQUILO, TIENIALQUILO, PIDINIALQUILO, OPCIONALMENTE FENIALQUILO SUBSTITUIDO O UN GRUPO DE LA FORMULA EN LA QUE R ELEVADO 3 ES ALQUILO, HALOALQUILO U OPCIONALMENTE FENIL O FENIALQUILO SUBSTITUIDO; X ES HIDROGENO, ALQUILO, ALCOXI, HALOGENO, O TRIFLUOROMETIL; M ES 0, 1 O 2; N ES 1 O 2.
ES91116337T 1990-09-27 1991-09-25 2-(4-piperidinil)-1h-pirido(4,3-b)indol-1-onas y compuestos relacionados, compuestos intermedios y procedimiento para su preparacion. Expired - Lifetime ES2082078T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07588870 US5102889B1 (en) 1990-09-27 1990-09-27 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds

Publications (1)

Publication Number Publication Date
ES2082078T3 true ES2082078T3 (es) 1996-03-16

Family

ID=24355647

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91116337T Expired - Lifetime ES2082078T3 (es) 1990-09-27 1991-09-25 2-(4-piperidinil)-1h-pirido(4,3-b)indol-1-onas y compuestos relacionados, compuestos intermedios y procedimiento para su preparacion.

Country Status (22)

Country Link
US (1) US5102889B1 (es)
EP (1) EP0481254B1 (es)
JP (1) JP3241762B2 (es)
KR (1) KR100210338B1 (es)
AT (1) ATE132148T1 (es)
AU (1) AU8475091A (es)
CA (1) CA2052424C (es)
CS (1) CS295191A3 (es)
DE (1) DE69115833T2 (es)
DK (1) DK0481254T3 (es)
ES (1) ES2082078T3 (es)
FI (1) FI914503A (es)
GR (1) GR3018746T3 (es)
HU (1) HUT59405A (es)
IE (1) IE72156B1 (es)
IL (3) IL113439A (es)
NO (1) NO913777L (es)
NZ (2) NZ248705A (es)
PT (1) PT99074B (es)
TW (1) TW199159B (es)
YU (1) YU158691A (es)
ZA (1) ZA917691B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4975445A (en) * 1989-12-06 1990-12-04 Warner-Lambert Company Substituted cyclohexenes as central nervous system agents
WO2001058869A2 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
KR102570307B1 (ko) * 2016-10-31 2023-08-25 주식회사 이엔에프테크놀로지 식각 조성물
CN109400617A (zh) * 2019-01-09 2019-03-01 湖北大学 一种新型吲哚并吡喃酮骨架化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
DE2557341A1 (de) * 1975-12-19 1977-06-30 Hoechst Ag Basisch substituierte indolderivate und verfahren zu ihrer herstellung
US4432978A (en) * 1979-07-30 1984-02-21 Pfizer Inc. Hexahydro-trans-pyridoindole
US4252811A (en) * 1979-07-30 1981-02-24 Pfizer Inc. Hexahydro-trans-pyridoindole neuroleptic agents
FR2619111B1 (fr) * 1987-08-07 1991-01-11 Synthelabo Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique
DE3851597T2 (de) * 1987-09-03 1995-01-26 Glaxo Group Ltd Lactamderivate.
IL91167A (en) * 1988-08-02 1993-06-10 Glaxo Group Ltd Substituted 2-(imidazolymethyl)-pyrido- (and azepino-) indol-1-one derivatives, their preparation and pharmaceutical compositions containing them
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
EP0481254A3 (en) 1992-05-06
PT99074B (pt) 1999-02-26
GR3018746T3 (en) 1996-04-30
DE69115833T2 (de) 1996-06-05
IL99579A0 (en) 1992-08-18
YU158691A (sh) 1994-06-10
IL99579A (en) 1999-04-11
HUT59405A (en) 1992-05-28
IL113439A (en) 1997-03-18
ATE132148T1 (de) 1996-01-15
JP3241762B2 (ja) 2001-12-25
NO913777D0 (no) 1991-09-26
NZ248705A (en) 1994-09-27
FI914503A (fi) 1992-03-28
PT99074A (pt) 1992-08-31
TW199159B (es) 1993-02-01
KR920006355A (ko) 1992-04-27
JPH04282381A (ja) 1992-10-07
IL113439A0 (en) 1995-07-31
ZA917691B (en) 1992-05-27
CA2052424A1 (en) 1992-03-28
EP0481254A2 (en) 1992-04-22
DE69115833D1 (de) 1996-02-08
CA2052424C (en) 2001-12-25
IE913388A1 (en) 1992-04-08
NZ239934A (en) 1994-09-27
EP0481254B1 (en) 1995-12-27
DK0481254T3 (da) 1996-04-29
AU8475091A (en) 1992-04-02
FI914503A0 (fi) 1991-09-25
KR100210338B1 (ko) 1999-07-15
US5102889A (en) 1992-04-07
NO913777L (no) 1992-03-30
US5102889B1 (en) 1993-05-11
HU913081D0 (en) 1992-01-28
IE72156B1 (en) 1997-03-26
CS295191A3 (en) 1992-04-15

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