IL113439A0 - Indole-piperidinyl compounds - Google Patents
Indole-piperidinyl compoundsInfo
- Publication number
- IL113439A0 IL113439A0 IL11343995A IL11343995A IL113439A0 IL 113439 A0 IL113439 A0 IL 113439A0 IL 11343995 A IL11343995 A IL 11343995A IL 11343995 A IL11343995 A IL 11343995A IL 113439 A0 IL113439 A0 IL 113439A0
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- hydrogen
- phenylalkyl
- optionally substituted
- indole
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 3
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- QDHSLJDFQLCDLT-UHFFFAOYSA-N 2-piperidin-4-yl-5h-pyrido[4,3-b]indol-1-one Chemical class C1=CC=2NC3=CC=CC=C3C=2C(=O)N1C1CCNCC1 QDHSLJDFQLCDLT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000561 anti-psychotic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07588870 US5102889B1 (en) | 1990-09-27 | 1990-09-27 | 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds |
| IL9957995 | 1995-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL113439A0 true IL113439A0 (en) | 1995-07-31 |
Family
ID=24355647
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9957991A IL99579A (en) | 1990-09-27 | 1991-09-26 | 2 -) 4 - Piperidinyl (- H1 - Pyrido] B-4,3 [Indole - 1 - Frequency and compound composition, and process for their preparation |
| IL113439A IL113439A (en) | 1990-09-27 | 1991-09-26 | 2-(1-substituted-4-piperidinyl) aminoethyl-1h-indole-3- carboxylic acids, 2-(1-substituted- 4-piperidinyl) carbamoylmethyl-1h- indoles and their homologs |
| IL11343995A IL113439A0 (en) | 1990-09-27 | 1995-04-20 | Indole-piperidinyl compounds |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9957991A IL99579A (en) | 1990-09-27 | 1991-09-26 | 2 -) 4 - Piperidinyl (- H1 - Pyrido] B-4,3 [Indole - 1 - Frequency and compound composition, and process for their preparation |
| IL113439A IL113439A (en) | 1990-09-27 | 1991-09-26 | 2-(1-substituted-4-piperidinyl) aminoethyl-1h-indole-3- carboxylic acids, 2-(1-substituted- 4-piperidinyl) carbamoylmethyl-1h- indoles and their homologs |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5102889B1 (xx) |
| EP (1) | EP0481254B1 (xx) |
| JP (1) | JP3241762B2 (xx) |
| KR (1) | KR100210338B1 (xx) |
| AT (1) | ATE132148T1 (xx) |
| AU (1) | AU8475091A (xx) |
| CA (1) | CA2052424C (xx) |
| CS (1) | CS295191A3 (xx) |
| DE (1) | DE69115833T2 (xx) |
| DK (1) | DK0481254T3 (xx) |
| ES (1) | ES2082078T3 (xx) |
| FI (1) | FI914503A (xx) |
| GR (1) | GR3018746T3 (xx) |
| HU (1) | HUT59405A (xx) |
| IE (1) | IE72156B1 (xx) |
| IL (3) | IL99579A (xx) |
| NO (1) | NO913777L (xx) |
| NZ (2) | NZ248705A (xx) |
| PT (1) | PT99074B (xx) |
| TW (1) | TW199159B (xx) |
| YU (1) | YU158691A (xx) |
| ZA (1) | ZA917691B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975445A (en) * | 1989-12-06 | 1990-12-04 | Warner-Lambert Company | Substituted cyclohexenes as central nervous system agents |
| JP2004502642A (ja) * | 2000-02-11 | 2004-01-29 | ブリストル−マイヤーズ スクイブ カンパニー | カンナビノイドレセプターモジュレーター、それらの製造方法、および呼吸系および非呼吸系疾患の処置のためのカンナビノイドレセプターモジュレーターの使用 |
| KR102570307B1 (ko) * | 2016-10-31 | 2023-08-25 | 주식회사 이엔에프테크놀로지 | 식각 조성물 |
| CN109400617A (zh) * | 2019-01-09 | 2019-03-01 | 湖北大学 | 一种新型吲哚并吡喃酮骨架化合物及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205452A1 (es) * | 1973-12-06 | 1976-05-07 | Endo Lab | Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles |
| DE2557341A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
| US4252811A (en) * | 1979-07-30 | 1981-02-24 | Pfizer Inc. | Hexahydro-trans-pyridoindole neuroleptic agents |
| US4432978A (en) * | 1979-07-30 | 1984-02-21 | Pfizer Inc. | Hexahydro-trans-pyridoindole |
| FR2619111B1 (fr) * | 1987-08-07 | 1991-01-11 | Synthelabo | Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique |
| ATE111910T1 (de) * | 1987-09-03 | 1994-10-15 | Glaxo Group Ltd | Lactamderivate. |
| ATE138659T1 (de) * | 1988-08-02 | 1996-06-15 | Glaxo Group Ltd | Lactamderivate |
| GB8904551D0 (en) * | 1989-02-28 | 1989-04-12 | Glaxo Group Ltd | Chemical compounds |
-
1990
- 1990-09-27 US US07588870 patent/US5102889B1/en not_active Expired - Fee Related
-
1991
- 1991-09-25 DE DE69115833T patent/DE69115833T2/de not_active Expired - Fee Related
- 1991-09-25 DK DK91116337.6T patent/DK0481254T3/da active
- 1991-09-25 ES ES91116337T patent/ES2082078T3/es not_active Expired - Lifetime
- 1991-09-25 TW TW080107539A patent/TW199159B/zh active
- 1991-09-25 EP EP91116337A patent/EP0481254B1/en not_active Expired - Lifetime
- 1991-09-25 NZ NZ248705A patent/NZ248705A/xx unknown
- 1991-09-25 AT AT91116337T patent/ATE132148T1/de not_active IP Right Cessation
- 1991-09-25 FI FI914503A patent/FI914503A/fi not_active Application Discontinuation
- 1991-09-25 NZ NZ239934A patent/NZ239934A/en unknown
- 1991-09-26 CS CS912951A patent/CS295191A3/cs unknown
- 1991-09-26 IL IL9957991A patent/IL99579A/en not_active IP Right Cessation
- 1991-09-26 JP JP27344091A patent/JP3241762B2/ja not_active Expired - Fee Related
- 1991-09-26 IL IL113439A patent/IL113439A/xx not_active IP Right Cessation
- 1991-09-26 ZA ZA917691A patent/ZA917691B/xx unknown
- 1991-09-26 HU HU913081A patent/HUT59405A/hu unknown
- 1991-09-26 YU YU158691A patent/YU158691A/sh unknown
- 1991-09-26 IE IE338891A patent/IE72156B1/en not_active IP Right Cessation
- 1991-09-26 NO NO91913777A patent/NO913777L/no unknown
- 1991-09-26 AU AU84750/91A patent/AU8475091A/en not_active Abandoned
- 1991-09-26 CA CA002052424A patent/CA2052424C/en not_active Expired - Fee Related
- 1991-09-26 PT PT99074A patent/PT99074B/pt not_active IP Right Cessation
- 1991-09-27 KR KR1019910016849A patent/KR100210338B1/ko not_active IP Right Cessation
-
1995
- 1995-04-20 IL IL11343995A patent/IL113439A0/xx unknown
-
1996
- 1996-01-19 GR GR960400135T patent/GR3018746T3/el unknown
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