PT99074A - Processo para a preparacao de 2-(4-piridinil)-1h-pirido{4,3-b}-onas e compostos afins e seus intermediarios e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de 2-(4-piridinil)-1h-pirido{4,3-b}-onas e compostos afins e seus intermediarios e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT99074A PT99074A PT99074A PT9907491A PT99074A PT 99074 A PT99074 A PT 99074A PT 99074 A PT99074 A PT 99074A PT 9907491 A PT9907491 A PT 9907491A PT 99074 A PT99074 A PT 99074A
- Authority
- PT
- Portugal
- Prior art keywords
- auds
- pyrid
- intermediaries
- pyridinyl
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- -1 4-PYRIDINYL Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 3
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- QDHSLJDFQLCDLT-UHFFFAOYSA-N 2-piperidin-4-yl-5h-pyrido[4,3-b]indol-1-one Chemical class C1=CC=2NC3=CC=CC=C3C=2C(=O)N1C1CCNCC1 QDHSLJDFQLCDLT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000561 anti-psychotic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07588870 US5102889B1 (en) | 1990-09-27 | 1990-09-27 | 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99074A true PT99074A (pt) | 1992-08-31 |
| PT99074B PT99074B (pt) | 1999-02-26 |
Family
ID=24355647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99074A PT99074B (pt) | 1990-09-27 | 1991-09-26 | Processo para a preparacao de 2-(4-piridinil)-1h-pirido{4,3-b}-onas e compostos afins e seus intermediarios e de composicoes farmaceuticas que os contem |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5102889B1 (pt) |
| EP (1) | EP0481254B1 (pt) |
| JP (1) | JP3241762B2 (pt) |
| KR (1) | KR100210338B1 (pt) |
| AT (1) | ATE132148T1 (pt) |
| AU (1) | AU8475091A (pt) |
| CA (1) | CA2052424C (pt) |
| CS (1) | CS295191A3 (pt) |
| DE (1) | DE69115833T2 (pt) |
| DK (1) | DK0481254T3 (pt) |
| ES (1) | ES2082078T3 (pt) |
| FI (1) | FI914503A (pt) |
| GR (1) | GR3018746T3 (pt) |
| HU (1) | HUT59405A (pt) |
| IE (1) | IE72156B1 (pt) |
| IL (3) | IL113439A (pt) |
| NO (1) | NO913777L (pt) |
| NZ (2) | NZ248705A (pt) |
| PT (1) | PT99074B (pt) |
| TW (1) | TW199159B (pt) |
| YU (1) | YU158691A (pt) |
| ZA (1) | ZA917691B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975445A (en) * | 1989-12-06 | 1990-12-04 | Warner-Lambert Company | Substituted cyclohexenes as central nervous system agents |
| JP2004502642A (ja) * | 2000-02-11 | 2004-01-29 | ブリストル−マイヤーズ スクイブ カンパニー | カンナビノイドレセプターモジュレーター、それらの製造方法、および呼吸系および非呼吸系疾患の処置のためのカンナビノイドレセプターモジュレーターの使用 |
| KR102570307B1 (ko) * | 2016-10-31 | 2023-08-25 | 주식회사 이엔에프테크놀로지 | 식각 조성물 |
| CN109400617A (zh) * | 2019-01-09 | 2019-03-01 | 湖北大学 | 一种新型吲哚并吡喃酮骨架化合物及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205452A1 (es) * | 1973-12-06 | 1976-05-07 | Endo Lab | Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles |
| DE2557341A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
| US4252811A (en) * | 1979-07-30 | 1981-02-24 | Pfizer Inc. | Hexahydro-trans-pyridoindole neuroleptic agents |
| US4432978A (en) * | 1979-07-30 | 1984-02-21 | Pfizer Inc. | Hexahydro-trans-pyridoindole |
| FR2619111B1 (fr) * | 1987-08-07 | 1991-01-11 | Synthelabo | Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique |
| PH25493A (en) * | 1987-09-03 | 1991-07-24 | Glaxo Group Ltd | 2,3,4,5-tetrahydro-2-£(imidazol-(or-5)-yl)methyl-ih-pyrido£4,3-b|indol-1-ones , derivatives having 5-ht antagonist activity 3 |
| ES2088389T3 (es) * | 1988-08-02 | 1996-08-16 | Glaxo Group Ltd | Derivados de lactamas. |
| GB8904551D0 (en) * | 1989-02-28 | 1989-04-12 | Glaxo Group Ltd | Chemical compounds |
-
1990
- 1990-09-27 US US07588870 patent/US5102889B1/en not_active Expired - Fee Related
-
1991
- 1991-09-25 TW TW080107539A patent/TW199159B/zh active
- 1991-09-25 ES ES91116337T patent/ES2082078T3/es not_active Expired - Lifetime
- 1991-09-25 NZ NZ248705A patent/NZ248705A/xx unknown
- 1991-09-25 AT AT91116337T patent/ATE132148T1/de not_active IP Right Cessation
- 1991-09-25 DK DK91116337.6T patent/DK0481254T3/da active
- 1991-09-25 EP EP91116337A patent/EP0481254B1/en not_active Expired - Lifetime
- 1991-09-25 FI FI914503A patent/FI914503A/fi not_active Application Discontinuation
- 1991-09-25 DE DE69115833T patent/DE69115833T2/de not_active Expired - Fee Related
- 1991-09-25 NZ NZ239934A patent/NZ239934A/en unknown
- 1991-09-26 IL IL113439A patent/IL113439A/xx not_active IP Right Cessation
- 1991-09-26 AU AU84750/91A patent/AU8475091A/en not_active Abandoned
- 1991-09-26 YU YU158691A patent/YU158691A/sh unknown
- 1991-09-26 PT PT99074A patent/PT99074B/pt not_active IP Right Cessation
- 1991-09-26 CA CA002052424A patent/CA2052424C/en not_active Expired - Fee Related
- 1991-09-26 IL IL9957991A patent/IL99579A/en not_active IP Right Cessation
- 1991-09-26 IE IE338891A patent/IE72156B1/en not_active IP Right Cessation
- 1991-09-26 CS CS912951A patent/CS295191A3/cs unknown
- 1991-09-26 NO NO91913777A patent/NO913777L/no unknown
- 1991-09-26 JP JP27344091A patent/JP3241762B2/ja not_active Expired - Fee Related
- 1991-09-26 ZA ZA917691A patent/ZA917691B/xx unknown
- 1991-09-26 HU HU913081A patent/HUT59405A/hu unknown
- 1991-09-27 KR KR1019910016849A patent/KR100210338B1/ko not_active IP Right Cessation
-
1995
- 1995-04-20 IL IL11343995A patent/IL113439A0/xx unknown
-
1996
- 1996-01-19 GR GR960400135T patent/GR3018746T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1252A (en) | (piperidinylalkyl)quinazoline derivatives and intermediates,process for their preparation and pharmaceutical compositions containing them | |
| BR8704582A (pt) | Processo para preparar derivados de piridinacarboxamida | |
| IL85988A (en) | 1-phenyl-3-naphthalenyloxy-propanamines,process for their preparation and pharmaceutical compositions containing them | |
| ES2058069T3 (es) | Derivados de 5h-1,3,4-tiadiazolo-(3,2-a)-pirimidin-5-ona y nuevo compuesto fungicida agricola-horticola que contiene dicho derivado. | |
| IL88303A (en) | Derivatives of 6-fluoro-7-û4-( (5-methyl-2-oxo-1,3- dioxolen-4-yl)methyl) piperazin-1-ylù-4 (1h)-oxo-1,3-thiazeto(3,2-a) quinoline-3-carboxylic acid | |
| PT81476B (pt) | Processo para a preparacao de derivados do acido quinolono-carboxilico | |
| DK43683D0 (da) | Aromatiske forbindelser med antihistamin-aktivitet, fremgangsmade til deres fremstilling samt deres anvendelse | |
| FI844333A0 (fi) | 11-substituerade 5h,11h-pyrrolo/2,1-c/ /1,4/benzoxazepiner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. | |
| DE3882438D1 (de) | Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung. | |
| AT389108B (de) | Neue pyridazinonderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen | |
| PT99074A (pt) | Processo para a preparacao de 2-(4-piridinil)-1h-pirido{4,3-b}-onas e compostos afins e seus intermediarios e de composicoes farmaceuticas que os contem | |
| DK0494604T3 (da) | 1-Piperazinyl-2-butener og -2-butyner, mellemprodukter derfor, en fremgangsmåde til fremstilling deraf og deres anvendelse | |
| ES509636A0 (es) | "procedimiento para preparar nuevos compuestos de aroilimidazol-2-onas". | |
| PT99331B (pt) | Processo para a preparacao de 3-difenilmetoxi-8-azabiciclo{3.2.1}octilalquil-tiazolidinomas e de composicoes farmaceuticas que as contem | |
| FR2626279B1 (fr) | Nouveaux derives de l'indolo(3,2,1-de)(1,4)-oxazino(2,3,4-ij)(1,5) naphthyridine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant | |
| PT99298A (pt) | Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem | |
| PT87954A (pt) | Processo para a preparacao de composicoes farmaceuticas contendo derivados de dioxopiperidina, com efeito antipsicotico | |
| ES2038672T3 (es) | Antagonistas h1 purinicos de la histamina, su preparacion y composiciones farmaceuticas que los contienen. | |
| FI933928A0 (fi) | Heteroarenylpiperaziner, foerfarande foer framstaellning av dessa och anvaendning som laekemedel | |
| EP0093050A3 (en) | Dithiino (1,4) (2,3-c) pyrrole derivatives, their preparation and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920408 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19981119 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20040531 |