PT99298A - Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem

Info

Publication number
PT99298A
PT99298A PT99298A PT9929891A PT99298A PT 99298 A PT99298 A PT 99298A PT 99298 A PT99298 A PT 99298A PT 9929891 A PT9929891 A PT 9929891A PT 99298 A PT99298 A PT 99298A
Authority
PT
Portugal
Prior art keywords
pyridinyl
trifluoromethyl
pyrazazyl
lactama
ethyl
Prior art date
Application number
PT99298A
Other languages
English (en)
Other versions
PT99298B (pt
Inventor
Michel Combourieu
Patrick Carlier
Claude Poisson
Andre Jean-Claude Monteil
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of PT99298A publication Critical patent/PT99298A/pt
Publication of PT99298B publication Critical patent/PT99298B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT99298A 1990-10-23 1991-10-22 Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem PT99298B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90402980 1990-10-23

Publications (2)

Publication Number Publication Date
PT99298A true PT99298A (pt) 1992-08-31
PT99298B PT99298B (pt) 1999-04-30

Family

ID=8205767

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99298A PT99298B (pt) 1990-10-23 1991-10-22 Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US5180726A (pt)
EP (1) EP0482696B1 (pt)
JP (1) JPH04282379A (pt)
KR (1) KR100226328B1 (pt)
AT (1) ATE132866T1 (pt)
AU (1) AU646611B2 (pt)
CA (1) CA2053980A1 (pt)
DE (1) DE69116302T2 (pt)
DK (1) DK0482696T3 (pt)
ES (1) ES2084763T3 (pt)
FI (1) FI100656B (pt)
GR (1) GR3019559T3 (pt)
IE (1) IE70331B1 (pt)
NZ (1) NZ240298A (pt)
PT (1) PT99298B (pt)
ZA (1) ZA918221B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701260B1 (fr) * 1993-02-05 1995-05-05 Esteve Labor Dr Dérivés de 2-[4-(4-azolylbutyl)-1-pipérazinyl]-5-hydroxypyrimidine, leur préparation et leur application en tant que médicaments.
AU6517196A (en) * 1995-07-13 1997-02-10 Knoll Aktiengesellschaft Piperazine derivatives as therapeutic agents
US6150367A (en) * 1997-10-20 2000-11-21 Council Of Scientific & Industrial Research 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes and their use in medical treatments

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
FI791926A (fi) * 1978-06-20 1979-12-21 Synthelabo Fenylpiperazinderivat
FR2429212A1 (fr) * 1978-06-20 1980-01-18 Synthelabo Derives de phenylpiperazine et leur application en therapeutique
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
CA1305148C (en) * 1987-08-19 1992-07-14 Hiromu Matsumura Carbamoylpyrrolidone derivatives and drugs for senile dementia

Also Published As

Publication number Publication date
ZA918221B (en) 1992-06-24
KR920008030A (ko) 1992-05-27
ES2084763T3 (es) 1996-05-16
PT99298B (pt) 1999-04-30
DK0482696T3 (da) 1996-05-20
US5180726A (en) 1993-01-19
AU646611B2 (en) 1994-02-24
FI100656B (fi) 1998-01-30
AU8608891A (en) 1992-04-30
IE913628A1 (en) 1992-05-22
CA2053980A1 (en) 1992-04-24
DE69116302D1 (de) 1996-02-22
ATE132866T1 (de) 1996-01-15
DE69116302T2 (de) 1996-05-30
JPH04282379A (ja) 1992-10-07
FI914971A (fi) 1992-04-24
EP0482696A1 (en) 1992-04-29
EP0482696B1 (en) 1996-01-10
FI914971A0 (fi) 1991-10-22
IE70331B1 (en) 1996-11-13
NZ240298A (en) 1993-02-25
GR3019559T3 (en) 1996-07-31
KR100226328B1 (ko) 1999-10-15

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920422

FG3A Patent granted, date of granting

Effective date: 19990112

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000731