PT99298A - Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem - Google Patents
Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT99298A PT99298A PT99298A PT9929891A PT99298A PT 99298 A PT99298 A PT 99298A PT 99298 A PT99298 A PT 99298A PT 9929891 A PT9929891 A PT 9929891A PT 99298 A PT99298 A PT 99298A
- Authority
- PT
- Portugal
- Prior art keywords
- pyridinyl
- trifluoromethyl
- pyrazazyl
- lactama
- ethyl
- Prior art date
Links
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical class F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 title 1
- 125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003951 lactams Chemical class 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP90402980 | 1990-10-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99298A true PT99298A (pt) | 1992-08-31 |
| PT99298B PT99298B (pt) | 1999-04-30 |
Family
ID=8205767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99298A PT99298B (pt) | 1990-10-23 | 1991-10-22 | Processo de preparacao de derivados lactama substituidos com 4-{4- ou 6-(trifluorometil)-2-piridinil}-1-piperazinilalquilo e de composicoes farmaceuticas que os contem |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5180726A (pt) |
| EP (1) | EP0482696B1 (pt) |
| JP (1) | JPH04282379A (pt) |
| KR (1) | KR100226328B1 (pt) |
| AT (1) | ATE132866T1 (pt) |
| AU (1) | AU646611B2 (pt) |
| CA (1) | CA2053980A1 (pt) |
| DE (1) | DE69116302T2 (pt) |
| DK (1) | DK0482696T3 (pt) |
| ES (1) | ES2084763T3 (pt) |
| FI (1) | FI100656B (pt) |
| GR (1) | GR3019559T3 (pt) |
| IE (1) | IE70331B1 (pt) |
| NZ (1) | NZ240298A (pt) |
| PT (1) | PT99298B (pt) |
| ZA (1) | ZA918221B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2701260B1 (fr) * | 1993-02-05 | 1995-05-05 | Esteve Labor Dr | Dérivés de 2-[4-(4-azolylbutyl)-1-pipérazinyl]-5-hydroxypyrimidine, leur préparation et leur application en tant que médicaments. |
| DE69615376T2 (de) * | 1995-07-13 | 2002-09-05 | Knoll Gmbh | Piperazin-derivate als heilmittel |
| US6150367A (en) * | 1997-10-20 | 2000-11-21 | Council Of Scientific & Industrial Research | 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes and their use in medical treatments |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
| AU521110B2 (en) * | 1978-06-20 | 1982-03-18 | Synthelabo | Phenylpiperazine derivatives |
| FR2429212A1 (fr) * | 1978-06-20 | 1980-01-18 | Synthelabo | Derives de phenylpiperazine et leur application en therapeutique |
| US4507303A (en) * | 1981-12-22 | 1985-03-26 | Sumitomo Chemical Company, Limited | Succinimide derivatives, compositions and method of use |
| US4361565A (en) * | 1981-12-28 | 1982-11-30 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines |
| US4619930A (en) * | 1985-01-16 | 1986-10-28 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use |
| US4675403A (en) * | 1985-10-16 | 1987-06-23 | American Home Products Corporation | 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity |
| US4732984A (en) * | 1985-10-17 | 1988-03-22 | American Home Products Corporation | Piperazinoisothiazolones with psychotropic activity |
| CA1305148C (en) * | 1987-08-19 | 1992-07-14 | Hiromu Matsumura | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
-
1991
- 1991-10-15 DK DK91202665.5T patent/DK0482696T3/da active
- 1991-10-15 ES ES91202665T patent/ES2084763T3/es not_active Expired - Lifetime
- 1991-10-15 DE DE69116302T patent/DE69116302T2/de not_active Expired - Fee Related
- 1991-10-15 ZA ZA918221A patent/ZA918221B/xx unknown
- 1991-10-15 AT AT91202665T patent/ATE132866T1/de not_active IP Right Cessation
- 1991-10-15 EP EP91202665A patent/EP0482696B1/en not_active Expired - Lifetime
- 1991-10-16 IE IE362891A patent/IE70331B1/en not_active IP Right Cessation
- 1991-10-17 US US07/777,963 patent/US5180726A/en not_active Expired - Fee Related
- 1991-10-21 NZ NZ240298A patent/NZ240298A/xx unknown
- 1991-10-22 PT PT99298A patent/PT99298B/pt not_active IP Right Cessation
- 1991-10-22 CA CA002053980A patent/CA2053980A1/en not_active Abandoned
- 1991-10-22 AU AU86088/91A patent/AU646611B2/en not_active Ceased
- 1991-10-22 KR KR1019910018561A patent/KR100226328B1/ko not_active Expired - Fee Related
- 1991-10-22 FI FI914971A patent/FI100656B/fi active
- 1991-10-23 JP JP3275798A patent/JPH04282379A/ja active Pending
-
1996
- 1996-04-04 GR GR960400938T patent/GR3019559T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI100656B (fi) | 1998-01-30 |
| ATE132866T1 (de) | 1996-01-15 |
| PT99298B (pt) | 1999-04-30 |
| FI914971L (fi) | 1992-04-24 |
| ES2084763T3 (es) | 1996-05-16 |
| AU8608891A (en) | 1992-04-30 |
| DE69116302D1 (de) | 1996-02-22 |
| KR100226328B1 (ko) | 1999-10-15 |
| EP0482696B1 (en) | 1996-01-10 |
| AU646611B2 (en) | 1994-02-24 |
| EP0482696A1 (en) | 1992-04-29 |
| CA2053980A1 (en) | 1992-04-24 |
| IE913628A1 (en) | 1992-05-22 |
| DK0482696T3 (da) | 1996-05-20 |
| FI914971A0 (fi) | 1991-10-22 |
| NZ240298A (en) | 1993-02-25 |
| IE70331B1 (en) | 1996-11-13 |
| ZA918221B (en) | 1992-06-24 |
| US5180726A (en) | 1993-01-19 |
| DE69116302T2 (de) | 1996-05-30 |
| KR920008030A (ko) | 1992-05-27 |
| GR3019559T3 (en) | 1996-07-31 |
| JPH04282379A (ja) | 1992-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920422 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990112 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000731 |