ZA918221B - 4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams - Google Patents

4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams

Info

Publication number
ZA918221B
ZA918221B ZA918221A ZA918221A ZA918221B ZA 918221 B ZA918221 B ZA 918221B ZA 918221 A ZA918221 A ZA 918221A ZA 918221 A ZA918221 A ZA 918221A ZA 918221 B ZA918221 B ZA 918221B
Authority
ZA
South Africa
Prior art keywords
pyridinyl
trifluoromethyl
piperazinyl
alkyl substituted
substituted lactams
Prior art date
Application number
ZA918221A
Other languages
English (en)
Inventor
Patrick Carlier
Carlier Patrick
Michel Combourieu
Combourieu Michel
Claude Poisson
Poisson Claude
Andre Jean-Claude Monteil
Jean-Claude Monteil Andre
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA918221B publication Critical patent/ZA918221B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA918221A 1990-10-23 1991-10-15 4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams ZA918221B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90402980 1990-10-23

Publications (1)

Publication Number Publication Date
ZA918221B true ZA918221B (en) 1992-06-24

Family

ID=8205767

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918221A ZA918221B (en) 1990-10-23 1991-10-15 4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams

Country Status (16)

Country Link
US (1) US5180726A (xx)
EP (1) EP0482696B1 (xx)
JP (1) JPH04282379A (xx)
KR (1) KR100226328B1 (xx)
AT (1) ATE132866T1 (xx)
AU (1) AU646611B2 (xx)
CA (1) CA2053980A1 (xx)
DE (1) DE69116302T2 (xx)
DK (1) DK0482696T3 (xx)
ES (1) ES2084763T3 (xx)
FI (1) FI100656B (xx)
GR (1) GR3019559T3 (xx)
IE (1) IE70331B1 (xx)
NZ (1) NZ240298A (xx)
PT (1) PT99298B (xx)
ZA (1) ZA918221B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701260B1 (fr) * 1993-02-05 1995-05-05 Esteve Labor Dr Dérivés de 2-[4-(4-azolylbutyl)-1-pipérazinyl]-5-hydroxypyrimidine, leur préparation et leur application en tant que médicaments.
JP4108747B2 (ja) * 1995-07-13 2008-06-25 アボット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 治療薬としてのピペラジン誘導体
US6150367A (en) * 1997-10-20 2000-11-21 Council Of Scientific & Industrial Research 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes and their use in medical treatments

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
DK251079A (da) * 1978-06-20 1979-12-21 Synthelabo Fremgangsmaade til fremstilling af phenylpiperazinderivater
FR2429212A1 (fr) * 1978-06-20 1980-01-18 Synthelabo Derives de phenylpiperazine et leur application en therapeutique
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
CA1305148C (en) * 1987-08-19 1992-07-14 Hiromu Matsumura Carbamoylpyrrolidone derivatives and drugs for senile dementia

Also Published As

Publication number Publication date
FI914971A0 (fi) 1991-10-22
ATE132866T1 (de) 1996-01-15
US5180726A (en) 1993-01-19
JPH04282379A (ja) 1992-10-07
KR920008030A (ko) 1992-05-27
DK0482696T3 (da) 1996-05-20
IE913628A1 (en) 1992-05-22
DE69116302D1 (de) 1996-02-22
EP0482696B1 (en) 1996-01-10
AU8608891A (en) 1992-04-30
PT99298A (pt) 1992-08-31
ES2084763T3 (es) 1996-05-16
GR3019559T3 (en) 1996-07-31
FI914971A (fi) 1992-04-24
NZ240298A (en) 1993-02-25
PT99298B (pt) 1999-04-30
DE69116302T2 (de) 1996-05-30
CA2053980A1 (en) 1992-04-24
FI100656B (fi) 1998-01-30
KR100226328B1 (ko) 1999-10-15
IE70331B1 (en) 1996-11-13
AU646611B2 (en) 1994-02-24
EP0482696A1 (en) 1992-04-29

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