ES2038672T3 - Antagonistas h1 purinicos de la histamina, su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Antagonistas h1 purinicos de la histamina, su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
ES2038672T3
ES2038672T3 ES198787309263T ES87309263T ES2038672T3 ES 2038672 T3 ES2038672 T3 ES 2038672T3 ES 198787309263 T ES198787309263 T ES 198787309263T ES 87309263 T ES87309263 T ES 87309263T ES 2038672 T3 ES2038672 T3 ES 2038672T3
Authority
ES
Spain
Prior art keywords
histamine
antagonists
hta
purine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787309263T
Other languages
English (en)
Inventor
Magid Abdel Megid Abou-Gharbia
Susan Thomson Nielsen
Michael Byron Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/921,553 external-priority patent/US4716166A/en
Priority claimed from GB878710843A external-priority patent/GB8710843D0/en
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of ES2038672T3 publication Critical patent/ES2038672T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION CONCIERNE A ANTAGONISTAS DE RECEPTORES DE HISTAMINA H1, DE FORMULA (I), EN LA QUE R1 ES HIDROGENO O UN GRUPO ALQUILO; R2 Y R3 SON UNO ALQUILO Y EL OTRO ES EL GRUPO (II), EN EL QUE R4 ES PIRIDIN-2-ILO, PIRIDIN-4-ILO, O FENILO QUE PUEDEN ESTAR OPCIONALMENTE SUSTITUIDOS POR UN HALOGENO, ALQUILO DE 1 A 6 C, NITRO, TRIFLUORMETILO, HIDROXI, O ALCOXI DE 1 A 6 C, Y R5 ES PIRIDIN-2-ILO, PIRIDIN-4-ILO O FENILO QUE PUEDEN ESTAR SUSTITUIDOS POR UN GRUPO ALQUILO O ALCOXI DE 1 A 6 C, NITRO O TRIFLUORMETILO.
ES198787309263T 1986-10-21 1987-10-20 Antagonistas h1 purinicos de la histamina, su preparacion y composiciones farmaceuticas que los contienen. Expired - Lifetime ES2038672T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/921,553 US4716166A (en) 1986-10-21 1986-10-21 Histamine H1 antagonists
GB878710843A GB8710843D0 (en) 1987-05-07 1987-05-07 Histamine h1 antagonists

Publications (1)

Publication Number Publication Date
ES2038672T3 true ES2038672T3 (es) 1993-08-01

Family

ID=26292217

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787309263T Expired - Lifetime ES2038672T3 (es) 1986-10-21 1987-10-20 Antagonistas h1 purinicos de la histamina, su preparacion y composiciones farmaceuticas que los contienen.

Country Status (10)

Country Link
EP (1) EP0271192B1 (es)
AT (1) ATE71378T1 (es)
CA (1) CA1283910C (es)
DE (1) DE3775905D1 (es)
ES (1) ES2038672T3 (es)
GB (1) GB2196963B (es)
GR (1) GR3003723T3 (es)
HU (1) HU196799B (es)
IE (1) IE61954B1 (es)
PT (1) PT85875B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3116873A1 (de) * 1981-04-28 1982-11-11 Alfa-Laval AB, 14700 Tumba Monohydrozyklon
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.

Also Published As

Publication number Publication date
GB2196963A (en) 1988-05-11
GB2196963B (en) 1990-10-17
GR3003723T3 (es) 1993-03-16
EP0271192A3 (en) 1988-06-29
DE3775905D1 (de) 1992-02-20
EP0271192B1 (en) 1992-01-08
ATE71378T1 (de) 1992-01-15
PT85875B (pt) 1990-07-31
PT85875A (en) 1987-11-01
HU196799B (en) 1989-01-30
GB8724545D0 (en) 1987-11-25
CA1283910C (en) 1991-05-07
HUT45056A (en) 1988-05-30
EP0271192A2 (en) 1988-06-15
IE61954B1 (en) 1994-11-30
IE872822L (en) 1988-04-21

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