ES2145905T3 - Procedimiento de produccion de acido 3-isoxazolcarboxilico. - Google Patents

Procedimiento de produccion de acido 3-isoxazolcarboxilico.

Info

Publication number
ES2145905T3
ES2145905T3 ES95909094T ES95909094T ES2145905T3 ES 2145905 T3 ES2145905 T3 ES 2145905T3 ES 95909094 T ES95909094 T ES 95909094T ES 95909094 T ES95909094 T ES 95909094T ES 2145905 T3 ES2145905 T3 ES 2145905T3
Authority
ES
Spain
Prior art keywords
acid
isoxazolcarboxilico
compound
production procedure
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95909094T
Other languages
English (en)
Inventor
Susumu Takada
Nobuo Chomei
Masaaki Uenaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2145905T3 publication Critical patent/ES2145905T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

SE PRESENTA UN PROCESO PARA LA PREPARACION DE ACIDO 3ISOXAZOLACARBOXILICO QUE ES UN PRODUCTO INTERMEDIO PARA LA PREPARACION DE COMPUESTOS UTILES. EL PROCESO SE CARACTERIZA EN QUE UN COMPUESTO DE LA FORMULA (I) SE HACE REACCIONAR CON UN HIDROXILAMINO PARA OBTENER UN COMPUESTO DE LA FORMULA (II), Y EL COMPUESTO ASI OBTENIDO SE TRATA CON UN ALCALI: EN DONDE R1 ES ALQUILO INFERIOR, R2 ES UN GRUPO PROTECTOR DE CARBOXIDO, X ES UN ATOMO DE HALOGENO, E Y ES UN ATOMO DE HIDROGENO, O X E Y TOMADAS JUNTAS PUEDEN FORMAR UN ANILLO SIMPLE.
ES95909094T 1994-02-16 1995-02-15 Procedimiento de produccion de acido 3-isoxazolcarboxilico. Expired - Lifetime ES2145905T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1938094 1994-02-16

Publications (1)

Publication Number Publication Date
ES2145905T3 true ES2145905T3 (es) 2000-07-16

Family

ID=11997714

Family Applications (2)

Application Number Title Priority Date Filing Date
ES95909094T Expired - Lifetime ES2145905T3 (es) 1994-02-16 1995-02-15 Procedimiento de produccion de acido 3-isoxazolcarboxilico.
ES99200655T Expired - Lifetime ES2183476T3 (es) 1994-02-16 1995-02-15 Procedimiento de preparacion del acido 3-isoxazol-carboxilico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES99200655T Expired - Lifetime ES2183476T3 (es) 1994-02-16 1995-02-15 Procedimiento de preparacion del acido 3-isoxazol-carboxilico.

Country Status (10)

Country Link
US (2) US5696271A (es)
EP (2) EP0739885B1 (es)
JP (1) JP3647455B2 (es)
KR (1) KR100330609B1 (es)
AU (1) AU1717495A (es)
CA (1) CA2183426A1 (es)
DE (2) DE69516396T2 (es)
ES (2) ES2145905T3 (es)
HU (1) HU214086B (es)
WO (1) WO1995022533A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
US20040014956A1 (en) 2002-02-01 2004-01-22 Sequitur, Inc. Double-stranded oligonucleotides
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
CN111491926B (zh) * 2017-12-15 2022-07-15 组合化学工业株式会社 5,5-二取代-4,5-二氢异噁唑的新型制造方法
CN115806531B (zh) * 2021-09-14 2024-05-28 新发药业有限公司 一种4,5-二氢-5,5-二苯基异噁唑-3-甲酸及其衍生物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019604A1 (fr) * 1991-05-01 1992-11-12 Taiho Pharmaceutical Co., Ltd. Nouveau derive d'isoxazole et sel de ce derive
DE4201047A1 (de) * 1992-01-17 1993-07-22 Bayer Ag Substituierte isoxazolcarbonsaeureamide
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
US5514505A (en) * 1995-05-15 1996-05-07 Xerox Corporation Method for obtaining improved image contrast in migration imaging members

Also Published As

Publication number Publication date
HU214086B (en) 1997-12-29
DE69516396T2 (de) 2000-08-31
HU9602278D0 (en) 1996-10-28
US5696271A (en) 1997-12-09
DE69527997D1 (de) 2002-10-02
EP0739885A1 (en) 1996-10-30
EP0739885B1 (en) 2000-04-19
DE69527997T2 (de) 2003-05-28
EP0957097A1 (en) 1999-11-17
KR970701180A (ko) 1997-03-17
JP3647455B2 (ja) 2005-05-11
EP0957097B1 (en) 2002-08-28
EP0739885A4 (en) 1997-04-16
HUT75051A (en) 1997-03-28
US5760244A (en) 1998-06-02
AU1717495A (en) 1995-09-04
WO1995022533A1 (fr) 1995-08-24
KR100330609B1 (ko) 2002-11-22
ES2183476T3 (es) 2003-03-16
CA2183426A1 (en) 1995-08-24
DE69516396D1 (de) 2000-05-25

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