YU47859B - Novi 5h-benzodiazepin derivat farmaceutski preparati koji sadrže isti i postupak za njihovo dobivanje - Google Patents

Novi 5h-benzodiazepin derivat farmaceutski preparati koji sadrže isti i postupak za njihovo dobivanje

Info

Publication number
YU47859B
YU47859B YU166991A YU166991A YU47859B YU 47859 B YU47859 B YU 47859B YU 166991 A YU166991 A YU 166991A YU 166991 A YU166991 A YU 166991A YU 47859 B YU47859 B YU 47859B
Authority
YU
Yugoslavia
Prior art keywords
new
benzodiazepine
derivat
procedure
production
Prior art date
Application number
YU166991A
Other languages
English (en)
Other versions
YU166991A (sh
Inventor
F. Andrasi
P. Botka
K. Goldschmidt
T. Hamori
G. Horvath
J. Korosi
I. Maravcsik
M. Rusz
E. Tomori
G. Zolyomi
Original Assignee
Egys Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egys Gyogyszergyar filed Critical Egys Gyogyszergyar
Publication of YU166991A publication Critical patent/YU166991A/sh
Publication of YU47859B publication Critical patent/YU47859B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NOVI 5H-BENZODIAZEPIN DERIVAT FARMACEUTSKI PREPARATI KOJI SADRŽE ISTI I POSTUPAK ZA NJIHOVO DOBIVANJE, novi 1-(3-hlorofenil)-4-hidroksimetil-7,8-dimetoksi-5H-2,3-benzodiazepin formule (I) i njihove farmaceutski prihvatljive adicione soli kiselina.- Prijava sadrži još 1 nezavisan i 4 zavisna zahteva.
YU166991A 1990-10-17 1991-10-17 Novi 5h-benzodiazepin derivat farmaceutski preparati koji sadrže isti i postupak za njihovo dobivanje YU47859B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU906469A HU207055B (en) 1990-10-17 1990-10-17 Process for producing new 5h-2,3-benzodiazepine derivative and pharmaceutical compositions comprising same

Publications (2)

Publication Number Publication Date
YU166991A YU166991A (sh) 1994-06-10
YU47859B true YU47859B (sh) 1996-02-19

Family

ID=10971685

Family Applications (1)

Application Number Title Priority Date Filing Date
YU166991A YU47859B (sh) 1990-10-17 1991-10-17 Novi 5h-benzodiazepin derivat farmaceutski preparati koji sadrže isti i postupak za njihovo dobivanje

Country Status (28)

Country Link
US (1) US5204343A (sh)
JP (1) JPH04282374A (sh)
KR (1) KR920008011A (sh)
CN (1) CN1033582C (sh)
AT (1) AT399506B (sh)
AU (1) AU648111B2 (sh)
BE (1) BE1004995A3 (sh)
BG (1) BG95336A (sh)
CA (1) CA2053622A1 (sh)
CH (1) CH682400A5 (sh)
CZ (1) CZ282249B6 (sh)
DE (1) DE4134402A1 (sh)
DK (1) DK174891A (sh)
ES (1) ES2036137B1 (sh)
FI (1) FI914918A (sh)
FR (1) FR2668148B1 (sh)
GB (1) GB2248838B (sh)
GR (1) GR1001068B (sh)
HU (1) HU207055B (sh)
IL (1) IL99637A (sh)
IT (1) IT1256279B (sh)
NL (1) NL9101741A (sh)
NO (1) NO914056L (sh)
PL (1) PL167108B1 (sh)
RU (1) RU2058982C1 (sh)
SE (1) SE506380C2 (sh)
YU (1) YU47859B (sh)
ZA (1) ZA918273B (sh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9701284A3 (en) * 1997-07-24 2005-11-28 Egyt Gyogyszervegyeszeti Gyar Use of 2,3-benzodiazepine derivatives for producing pharmaceutical compositions for treating and prophylacting illnesses and conditions connected with the endogene opioide system
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
CA2510275A1 (en) * 2002-12-03 2004-08-19 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
JP2006510634A (ja) * 2002-12-03 2006-03-30 ヴェラ ファーマスーティカルズ インコーポレイテッド １−（３，４−ジメトキシフェニル）−４−メチル−５−エチル−７−メトキシ−８−ヒドロキシ−５ｈ−２，３−ベンゾジアゼピンの製薬組成物及びその用途
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2257274A1 (en) * 1974-01-16 1975-08-08 Synthelabo Substd. 1,2-diazepin-7-one analgesic and psychotropic agents - prepd by cyclizing a delta keto acid and a substd hydrazine
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
DE4134402A1 (de) 1992-05-14
KR920008011A (ko) 1992-05-27
SE9103022D0 (sv) 1991-10-17
CH682400A5 (de) 1993-09-15
HU207055B (en) 1993-03-01
IL99637A0 (en) 1992-08-18
GB9122090D0 (en) 1991-11-27
PL167108B1 (pl) 1995-07-31
BE1004995A3 (fr) 1993-03-16
FR2668148B1 (fr) 1993-07-30
CA2053622A1 (en) 1992-04-18
IL99637A (en) 1996-06-18
HUT59381A (en) 1992-05-28
PL292091A1 (en) 1992-06-26
FI914918A (fi) 1992-04-18
ATA207191A (de) 1994-10-15
FR2668148A1 (fr) 1992-04-24
ES2036137A1 (es) 1993-05-01
SE9103022L (sv) 1992-04-18
ITMI912745A0 (it) 1991-10-17
IT1256279B (it) 1995-11-29
BG95336A (bg) 1993-12-24
GB2248838A (en) 1992-04-22
SE506380C2 (sv) 1997-12-08
CN1060838A (zh) 1992-05-06
ZA918273B (en) 1994-10-04
GB2248838B (en) 1994-04-06
DK174891D0 (da) 1991-10-16
ES2036137B1 (es) 1994-03-01
HU906469D0 (en) 1991-04-29
CN1033582C (zh) 1996-12-18
JPH04282374A (ja) 1992-10-07
GR1001068B (el) 1993-04-28
RU2058982C1 (ru) 1996-04-27
AT399506B (de) 1995-05-26
CS314191A3 (en) 1992-05-13
AU8592291A (en) 1992-04-30
ITMI912745A1 (it) 1993-04-17
AU648111B2 (en) 1994-04-14
NO914056L (no) 1992-04-21
YU166991A (sh) 1994-06-10
US5204343A (en) 1993-04-20
NL9101741A (nl) 1992-05-18
CZ282249B6 (cs) 1997-06-11
FI914918A0 (fi) 1991-10-17
NO914056D0 (no) 1991-10-16
GR910100426A (en) 1992-09-25
DK174891A (da) 1992-04-18

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