ITMI912745A1 - Derivati 5h-benzodiazepinici, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione. - Google Patents

Derivati 5h-benzodiazepinici, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione.

Info

Publication number
ITMI912745A1
ITMI912745A1 IT002745A ITMI912745A ITMI912745A1 IT MI912745 A1 ITMI912745 A1 IT MI912745A1 IT 002745 A IT002745 A IT 002745A IT MI912745 A ITMI912745 A IT MI912745A IT MI912745 A1 ITMI912745 A1 IT MI912745A1
Authority
IT
Italy
Prior art keywords
benzodiazepinic
derivatives
procedure
contain
preparation
Prior art date
Application number
IT002745A
Other languages
English (en)
Inventor
Ferenc Andrasi
Peter Botka
Tamas Hamori
Gyula Horvath
Goldschmidt Katalin Horvath
Jeno Korosi
Imre Moravcsik
Marta Rusz
Eva Tomori
Gabor Zolyomi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ITMI912745A0 publication Critical patent/ITMI912745A0/it
Publication of ITMI912745A1 publication Critical patent/ITMI912745A1/it
Application granted granted Critical
Publication of IT1256279B publication Critical patent/IT1256279B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ITMI912745A 1990-10-17 1991-10-17 Derivati 5h-benzodiazepinici, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione. IT1256279B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU906469A HU207055B (en) 1990-10-17 1990-10-17 Process for producing new 5h-2,3-benzodiazepine derivative and pharmaceutical compositions comprising same

Publications (3)

Publication Number Publication Date
ITMI912745A0 ITMI912745A0 (it) 1991-10-17
ITMI912745A1 true ITMI912745A1 (it) 1993-04-17
IT1256279B IT1256279B (it) 1995-11-29

Family

ID=10971685

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI912745A IT1256279B (it) 1990-10-17 1991-10-17 Derivati 5h-benzodiazepinici, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione.

Country Status (28)

Country Link
US (1) US5204343A (it)
JP (1) JPH04282374A (it)
KR (1) KR920008011A (it)
CN (1) CN1033582C (it)
AT (1) AT399506B (it)
AU (1) AU648111B2 (it)
BE (1) BE1004995A3 (it)
BG (1) BG95336A (it)
CA (1) CA2053622A1 (it)
CH (1) CH682400A5 (it)
CZ (1) CZ282249B6 (it)
DE (1) DE4134402A1 (it)
DK (1) DK174891A (it)
ES (1) ES2036137B1 (it)
FI (1) FI914918A (it)
FR (1) FR2668148B1 (it)
GB (1) GB2248838B (it)
GR (1) GR1001068B (it)
HU (1) HU207055B (it)
IL (1) IL99637A (it)
IT (1) IT1256279B (it)
NL (1) NL9101741A (it)
NO (1) NO914056L (it)
PL (1) PL167108B1 (it)
RU (1) RU2058982C1 (it)
SE (1) SE506380C2 (it)
YU (1) YU47859B (it)
ZA (1) ZA918273B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9701284A3 (en) * 1997-07-24 2005-11-28 Egyt Gyogyszervegyeszeti Gyar Use of 2,3-benzodiazepine derivatives for producing pharmaceutical compositions for treating and prophylacting illnesses and conditions connected with the endogene opioide system
US6649607B2 (en) 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
MXPA05005895A (es) * 2002-12-03 2006-02-08 Vela Pharmaceuticals Inc Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma.
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
WO2004069155A2 (en) * 2002-12-03 2004-08-19 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2257274A1 (en) * 1974-01-16 1975-08-08 Synthelabo Substd. 1,2-diazepin-7-one analgesic and psychotropic agents - prepd by cyclizing a delta keto acid and a substd hydrazine
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
GB2248838A (en) 1992-04-22
SE9103022D0 (sv) 1991-10-17
GB9122090D0 (en) 1991-11-27
CZ282249B6 (cs) 1997-06-11
HUT59381A (en) 1992-05-28
DE4134402A1 (de) 1992-05-14
GB2248838B (en) 1994-04-06
FR2668148A1 (fr) 1992-04-24
CN1060838A (zh) 1992-05-06
SE506380C2 (sv) 1997-12-08
RU2058982C1 (ru) 1996-04-27
PL292091A1 (en) 1992-06-26
US5204343A (en) 1993-04-20
NL9101741A (nl) 1992-05-18
AT399506B (de) 1995-05-26
SE9103022L (sv) 1992-04-18
NO914056L (no) 1992-04-21
IT1256279B (it) 1995-11-29
IL99637A0 (en) 1992-08-18
CS314191A3 (en) 1992-05-13
CH682400A5 (de) 1993-09-15
ATA207191A (de) 1994-10-15
GR1001068B (el) 1993-04-28
AU8592291A (en) 1992-04-30
IL99637A (en) 1996-06-18
YU166991A (sh) 1994-06-10
JPH04282374A (ja) 1992-10-07
DK174891A (da) 1992-04-18
CN1033582C (zh) 1996-12-18
NO914056D0 (no) 1991-10-16
ES2036137B1 (es) 1994-03-01
ZA918273B (en) 1994-10-04
PL167108B1 (pl) 1995-07-31
ES2036137A1 (es) 1993-05-01
HU207055B (en) 1993-03-01
BG95336A (bg) 1993-12-24
FI914918A (fi) 1992-04-18
AU648111B2 (en) 1994-04-14
ITMI912745A0 (it) 1991-10-17
FR2668148B1 (fr) 1993-07-30
YU47859B (sh) 1996-02-19
FI914918A0 (fi) 1991-10-17
BE1004995A3 (fr) 1993-03-16
CA2053622A1 (en) 1992-04-18
HU906469D0 (en) 1991-04-29
DK174891D0 (da) 1991-10-16
GR910100426A (en) 1992-09-25
KR920008011A (ko) 1992-05-27

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971030