BG95336A - 5н-2,3-бензодиазепинови производни,съдържащи ги фармацевтични състави и метод за тяхното получаване - Google Patents

5н-2,3-бензодиазепинови производни,съдържащи ги фармацевтични състави и метод за тяхното получаване

Info

Publication number
BG95336A
BG95336A BG095336A BG9533691A BG95336A BG 95336 A BG95336 A BG 95336A BG 095336 A BG095336 A BG 095336A BG 9533691 A BG9533691 A BG 9533691A BG 95336 A BG95336 A BG 95336A
Authority
BG
Bulgaria
Prior art keywords
obtainment
pharmaceutical compositions
compositions containing
benzodiazepine derivatives
benzodiazepine
Prior art date
Application number
BG095336A
Other languages
English (en)
Inventor
Ferenc Andrasi
Peter Botka
Katalin Goldschmidt
Tamas Hamori
Gyula Horvath
Jeno Koroesi
Imre Moravcsik
Marta Rusz
Eva Tomori
Gabor Zolyomi
Original Assignee
Egis Gyogyszergyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Rt. filed Critical Egis Gyogyszergyar Rt.
Publication of BG95336A publication Critical patent/BG95336A/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BG095336A 1990-10-17 1991-10-17 5н-2,3-бензодиазепинови производни,съдържащи ги фармацевтични състави и метод за тяхното получаване BG95336A (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU906469A HU207055B (en) 1990-10-17 1990-10-17 Process for producing new 5h-2,3-benzodiazepine derivative and pharmaceutical compositions comprising same

Publications (1)

Publication Number Publication Date
BG95336A true BG95336A (bg) 1993-12-24

Family

ID=10971685

Family Applications (1)

Application Number Title Priority Date Filing Date
BG095336A BG95336A (bg) 1990-10-17 1991-10-17 5н-2,3-бензодиазепинови производни,съдържащи ги фармацевтични състави и метод за тяхното получаване

Country Status (28)

Country Link
US (1) US5204343A (bg)
JP (1) JPH04282374A (bg)
KR (1) KR920008011A (bg)
CN (1) CN1033582C (bg)
AT (1) AT399506B (bg)
AU (1) AU648111B2 (bg)
BE (1) BE1004995A3 (bg)
BG (1) BG95336A (bg)
CA (1) CA2053622A1 (bg)
CH (1) CH682400A5 (bg)
CZ (1) CZ282249B6 (bg)
DE (1) DE4134402A1 (bg)
DK (1) DK174891A (bg)
ES (1) ES2036137B1 (bg)
FI (1) FI914918A (bg)
FR (1) FR2668148B1 (bg)
GB (1) GB2248838B (bg)
GR (1) GR1001068B (bg)
HU (1) HU207055B (bg)
IL (1) IL99637A (bg)
IT (1) IT1256279B (bg)
NL (1) NL9101741A (bg)
NO (1) NO914056L (bg)
PL (1) PL167108B1 (bg)
RU (1) RU2058982C1 (bg)
SE (1) SE506380C2 (bg)
YU (1) YU47859B (bg)
ZA (1) ZA918273B (bg)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9701284A3 (en) * 1997-07-24 2005-11-28 Egyt Gyogyszervegyeszeti Gyar Use of 2,3-benzodiazepine derivatives for producing pharmaceutical compositions for treating and prophylacting illnesses and conditions connected with the endogene opioide system
US6649607B2 (en) 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
MXPA05005895A (es) * 2002-12-03 2006-02-08 Vela Pharmaceuticals Inc Composicion farmaceutica de 1-(3, 4-dimetoxifenil)-4 -metil-5-etil -7-metoxi-8 -hidroxi- 5h-2, 3-benzodiacepina y usos de la misma.
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
WO2004069155A2 (en) * 2002-12-03 2004-08-19 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2257274A1 (en) * 1974-01-16 1975-08-08 Synthelabo Substd. 1,2-diazepin-7-one analgesic and psychotropic agents - prepd by cyclizing a delta keto acid and a substd hydrazine
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines

Also Published As

Publication number Publication date
GB2248838A (en) 1992-04-22
SE9103022D0 (sv) 1991-10-17
GB9122090D0 (en) 1991-11-27
ITMI912745A1 (it) 1993-04-17
CZ282249B6 (cs) 1997-06-11
HUT59381A (en) 1992-05-28
DE4134402A1 (de) 1992-05-14
GB2248838B (en) 1994-04-06
FR2668148A1 (fr) 1992-04-24
CN1060838A (zh) 1992-05-06
SE506380C2 (sv) 1997-12-08
RU2058982C1 (ru) 1996-04-27
PL292091A1 (en) 1992-06-26
US5204343A (en) 1993-04-20
NL9101741A (nl) 1992-05-18
AT399506B (de) 1995-05-26
SE9103022L (sv) 1992-04-18
NO914056L (no) 1992-04-21
IT1256279B (it) 1995-11-29
IL99637A0 (en) 1992-08-18
CS314191A3 (en) 1992-05-13
CH682400A5 (de) 1993-09-15
ATA207191A (de) 1994-10-15
GR1001068B (el) 1993-04-28
AU8592291A (en) 1992-04-30
IL99637A (en) 1996-06-18
YU166991A (sh) 1994-06-10
JPH04282374A (ja) 1992-10-07
DK174891A (da) 1992-04-18
CN1033582C (zh) 1996-12-18
NO914056D0 (no) 1991-10-16
ES2036137B1 (es) 1994-03-01
ZA918273B (en) 1994-10-04
PL167108B1 (pl) 1995-07-31
ES2036137A1 (es) 1993-05-01
HU207055B (en) 1993-03-01
FI914918A (fi) 1992-04-18
AU648111B2 (en) 1994-04-14
ITMI912745A0 (it) 1991-10-17
FR2668148B1 (fr) 1993-07-30
YU47859B (sh) 1996-02-19
FI914918A0 (fi) 1991-10-17
BE1004995A3 (fr) 1993-03-16
CA2053622A1 (en) 1992-04-18
HU906469D0 (en) 1991-04-29
DK174891D0 (da) 1991-10-16
GR910100426A (en) 1992-09-25
KR920008011A (ko) 1992-05-27

Similar Documents

Publication Publication Date Title
NO973479L (no) Substituerte heterosykliske forbindelser, fremgangsmåte for fremstilling og farmasöytiske blandinger inneholdende samme
FI963566A0 (fi) Uusia piperatsiinijohdoksia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä koostumuksia
BG97198A (bg) Диалкокси-пиридинил-бензимидазолови производни, метод за получаването им и тяхното фармацевтично приложение
MA26453A1 (fr) Derives de 6-phenylpyridyl-2 amine et compositions pharmaceutiques les contenant
IT8521725A0 (it) Derivati di 5h-2,3-benzodiazepine, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
HUP0003690A3 (en) Polymeric derivatives of camptothecins, process for their preparation and pharmaceutical compositions containing them
HUP9700358A3 (en) New oxazolidinon derivatives, process for their preparation and pharmaceutical compositions containing them
FI942913A0 (fi) Isatiinijohdannaiset, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
MA26433A1 (fr) Derives de pyridylpyrrole, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2735777B1 (fr) Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
MA26425A1 (fr) Derives de lactames, procede pour leur preparation et compositions pharmaceutiques les contenant
HUP9601033A3 (en) Benzofurane derivatives, process for their preparation, use of them as intermediate and pharmaceutical compositions containing the compounds
HUP9702400A3 (en) Substituted camptothecin derivatives, process for their preparation and pharmaceutical compositions containing them
FI950625A (fi) Polysubstituoituja 3-asyyliamino-5-fenyyli-1,4-bentsodiatsepiini-2-onijohdannaisia, menetelmä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia
MA26501A1 (fr) Derives de quinoleine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
KR950700310A (ko) 헤테로트리사이클릭 유도체, 그의 제조방법 및 그를 함유하는 약제학적 조성물(heterotricyclic derivatives, process for their preparation and pharmaceutical compositions containing them)
BG95336A (bg) 5н-2,3-бензодиазепинови производни,съдържащи ги фармацевтични състави и метод за тяхното получаване
GB9617893D0 (en) New pharmaceutical derivatives, process for obtaining them and pharmaceutical compositions containing them
EE03395B1 (et) Bensotiasolooni derivaadid, protsessid ja kasutatud vaheühendid nende saamiseks ning neid sisaldavad ravimkoostised
IL82613A0 (en) 1-(hydroxystyryl)-5h-2,3-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
MA26441A1 (fr) Derives de pyrrolidinyl- et pyrrolinyl- ethylamine, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2772761B1 (fr) Nouveaux derives de n-phenylamide et n-pyridylamide, leur procede de preparation et compositions pharmaceutiques les contenant
HUP0001773A3 (en) Substituted tetrahydropyridin derivatives, method of preparation and pharmaceutical compositions containing them
FR2566774B1 (fr) Derives de 5h-2,3-benzodiazepine, leur procede de preparation et compositions pharmaceutiques les contenant
BG92749A (bg) Производни на аминопропанола,метод за тяхното получаване и фармацетични състави,съдържащи тези производни