YU40307B - Process for obtaining unsaturated 7-acylamido-3-cephem-4-carboxylic acid derivatives - Google Patents
Process for obtaining unsaturated 7-acylamido-3-cephem-4-carboxylic acid derivativesInfo
- Publication number
- YU40307B YU40307B YU2109/77A YU210977A YU40307B YU 40307 B YU40307 B YU 40307B YU 2109/77 A YU2109/77 A YU 2109/77A YU 210977 A YU210977 A YU 210977A YU 40307 B YU40307 B YU 40307B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- acylamido
- cephem
- carboxylic acid
- acid derivatives
- obtaining unsaturated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20173/77A IT1075277B (it) | 1977-02-11 | 1977-02-11 | Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione |
Publications (2)
Publication Number | Publication Date |
---|---|
YU210977A YU210977A (en) | 1982-10-31 |
YU40307B true YU40307B (en) | 1985-12-31 |
Family
ID=11164407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2109/77A YU40307B (en) | 1977-02-11 | 1977-09-06 | Process for obtaining unsaturated 7-acylamido-3-cephem-4-carboxylic acid derivatives |
Country Status (29)
Country | Link |
---|---|
US (3) | US4154830A (el) |
JP (2) | JPS5398991A (el) |
AT (2) | AT355206B (el) |
AU (2) | AU512934B2 (el) |
BE (2) | BE858433A (el) |
CA (2) | CA1103237A (el) |
CH (3) | CH632513A5 (el) |
CS (3) | CS196381B2 (el) |
CY (1) | CY1234A (el) |
DE (2) | DE2736471A1 (el) |
DK (2) | DK155944C (el) |
FI (2) | FI65259C (el) |
FR (3) | FR2380285A1 (el) |
GB (4) | GB1582295A (el) |
GR (2) | GR71901B (el) |
HK (1) | HK55284A (el) |
HU (2) | HU177596B (el) |
IL (3) | IL52708A0 (el) |
IT (1) | IT1075277B (el) |
MY (1) | MY8500446A (el) |
NL (2) | NL7708943A (el) |
NO (4) | NO152654C (el) |
NZ (2) | NZ184889A (el) |
PH (1) | PH16946A (el) |
SE (4) | SE7709002L (el) |
SG (1) | SG9484G (el) |
SU (4) | SU845788A3 (el) |
YU (1) | YU40307B (el) |
ZA (2) | ZA774835B (el) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1075277B (it) * | 1977-02-11 | 1985-04-22 | Erba Carlo Spa | Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione |
JPS5593413A (en) * | 1979-01-11 | 1980-07-15 | Osaka Gas Co Ltd | Lining method for inner surface of pipe |
US4331666A (en) * | 1979-05-11 | 1982-05-25 | Farmitalia Carlo Erba S.P.A. | 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid |
US4420477A (en) * | 1979-11-30 | 1983-12-13 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4405617A (en) * | 1980-02-11 | 1983-09-20 | Fujisawa Pharmaceutical Co., Ltd. | 3-(Propynyltetrazol)thiomethyl-3-cephems |
GB2076803B (en) * | 1980-05-16 | 1984-02-08 | Erba Farmitalia | Substituted 7-(a-oxy-imino-acetamido)-cephalosporins and process for their preparation |
GB2186875A (en) * | 1983-10-31 | 1987-08-26 | Fujisawa Pharmaceutical Co | New cephem compounds and processes for preparation thereof |
DE3689762T2 (de) * | 1985-12-13 | 1994-08-18 | Takeda Chemical Industries Ltd | Antibakterielle Verbindungen, ihre Herstellung und Verwendung. |
JPH0544294Y2 (el) * | 1986-06-10 | 1993-11-10 | ||
US5198445A (en) * | 1990-01-12 | 1993-03-30 | The Dow Chemical Company | Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials |
JPH05504767A (ja) * | 1990-01-12 | 1993-07-22 | ザ・ダウ・ケミカル・カンパニー | 置換3―チオ―2―プロピンニトリルを含んだ組成物及びその工業用抗微生物物質としての使用 |
US5126349A (en) * | 1990-01-12 | 1992-06-30 | The Dow Chemical Company | Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial |
US5157051A (en) * | 1992-03-05 | 1992-10-20 | The Dow Chemical Company | Composition and use of 3-thiocyano-2-halo-2-propenenitriles as antimicrobial agents |
US5155119A (en) * | 1992-03-05 | 1992-10-13 | The Dow Chemical Company | 3-(2-pyridinylthio)-N-oxide, 2-halo-2-propenenitrile compounds useful as antimicrobials |
US5206227A (en) * | 1992-06-02 | 1993-04-27 | The Dow Chemical Company | Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials |
JP3115455B2 (ja) * | 1992-12-18 | 2000-12-04 | 明治製菓株式会社 | 新規セファロスポリン誘導体 |
SE9802974D0 (sv) * | 1998-09-03 | 1998-09-03 | Astra Ab | New crystalline forms |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1478055A (en) * | 1973-07-27 | 1977-06-29 | Erba Carlo Spa | Cephalosporin compounds |
IT1075277B (it) * | 1977-02-11 | 1985-04-22 | Erba Carlo Spa | Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione |
US3883520A (en) * | 1973-08-17 | 1975-05-13 | Smithkline Corp | Substituted mercaptoacetamidocephalosporins |
FI761035A (el) * | 1975-04-21 | 1976-10-22 | Erba Carlo Spa | |
ZA767084B (en) * | 1975-12-16 | 1977-10-26 | Erba Carlo Spa | Thiadiazolyl derivatives of 7-acylamido 3-cephem-4-carboxylic acid and process for their preparation |
US4057631A (en) * | 1976-09-02 | 1977-11-08 | Smithkline Corporation | 7-(α-Substituted phenylacetamido)-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-cephem-4-carboxylic acids |
US4079134A (en) * | 1976-09-24 | 1978-03-14 | Smithkline Corporation | 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids |
-
1977
- 1977-02-11 IT IT20173/77A patent/IT1075277B/it active
- 1977-08-08 US US05/822,638 patent/US4154830A/en not_active Expired - Lifetime
- 1977-08-08 DK DK353577A patent/DK155944C/da not_active IP Right Cessation
- 1977-08-08 NO NO772779A patent/NO152654C/no unknown
- 1977-08-09 CY CY1234A patent/CY1234A/xx unknown
- 1977-08-09 GB GB33418/77A patent/GB1582295A/en not_active Expired
- 1977-08-09 SE SE7709002A patent/SE7709002L/xx not_active Application Discontinuation
- 1977-08-09 GB GB43324/79A patent/GB1590610A/en not_active Expired
- 1977-08-10 CA CA284,460A patent/CA1103237A/en not_active Expired
- 1977-08-10 FI FI772411A patent/FI65259C/fi not_active IP Right Cessation
- 1977-08-10 HU HU77EA176A patent/HU177596B/hu not_active IP Right Cessation
- 1977-08-10 NZ NZ184889A patent/NZ184889A/xx unknown
- 1977-08-10 ZA ZA00774835A patent/ZA774835B/xx unknown
- 1977-08-11 AT AT585677A patent/AT355206B/de not_active IP Right Cessation
- 1977-08-11 CH CH984577A patent/CH632513A5/de not_active IP Right Cessation
- 1977-08-11 CS CS775327A patent/CS196381B2/cs unknown
- 1977-08-11 GR GR54135A patent/GR71901B/el unknown
- 1977-08-12 DE DE19772736471 patent/DE2736471A1/de active Granted
- 1977-08-12 NL NL7708943A patent/NL7708943A/xx not_active Application Discontinuation
- 1977-08-12 IL IL52708A patent/IL52708A0/xx not_active IP Right Cessation
- 1977-08-12 AU AU27865/77A patent/AU512934B2/en not_active Expired
- 1977-08-12 FR FR7724952A patent/FR2380285A1/fr active Granted
- 1977-08-13 JP JP9742077A patent/JPS5398991A/ja active Granted
- 1977-08-22 SU SU772516753A patent/SU845788A3/ru active
- 1977-09-06 BE BE180695A patent/BE858433A/xx not_active IP Right Cessation
- 1977-09-06 YU YU2109/77A patent/YU40307B/xx unknown
-
1978
- 1978-01-09 NO NO780074A patent/NO780074L/no unknown
- 1978-01-10 DK DK11578A patent/DK11578A/da not_active Application Discontinuation
- 1978-01-11 US US05/868,665 patent/US4172892A/en not_active Expired - Lifetime
- 1978-01-11 SE SE7800292A patent/SE7800292L/xx unknown
- 1978-01-11 GB GB1121/78A patent/GB1597261A/en not_active Expired
- 1978-01-11 ZA ZA00780181A patent/ZA78181B/xx unknown
- 1978-01-11 GB GB4691/80A patent/GB1597262A/en not_active Expired
- 1978-01-12 HU HU78EA182A patent/HU178918B/hu unknown
- 1978-01-13 NL NL7800443A patent/NL7800443A/xx not_active Application Discontinuation
- 1978-01-16 AU AU32476/78A patent/AU513444B2/en not_active Expired
- 1978-01-16 DE DE19782801644 patent/DE2801644A1/de not_active Withdrawn
- 1978-01-17 CS CS788042A patent/CS199714B2/cs unknown
- 1978-01-17 IL IL53830A patent/IL53830A/xx unknown
- 1978-01-17 CS CS78331A patent/CS199713B2/cs unknown
- 1978-01-17 NZ NZ186236A patent/NZ186236A/xx unknown
- 1978-01-17 AT AT32778A patent/AT356270B/de not_active IP Right Cessation
- 1978-01-19 GR GR55208A patent/GR72589B/el unknown
- 1978-01-20 PH PH20693A patent/PH16946A/en unknown
- 1978-01-24 FR FR7801928A patent/FR2384783A1/fr active Granted
- 1978-01-26 JP JP676978A patent/JPS53121788A/ja active Pending
- 1978-02-03 BE BE184877A patent/BE863625A/xx not_active IP Right Cessation
- 1978-02-10 FI FI780437A patent/FI780437A/fi not_active Application Discontinuation
- 1978-02-10 SU SU782578100A patent/SU856388A3/ru active
- 1978-02-10 CA CA296,689A patent/CA1108603A/en not_active Expired
- 1978-02-10 CH CH153278A patent/CH636359A5/de not_active IP Right Cessation
- 1978-07-28 SU SU782640405A patent/SU753361A3/ru active
-
1979
- 1979-04-26 SU SU792759905A patent/SU904524A3/ru active
- 1979-12-14 NO NO794101A patent/NO794101L/no unknown
-
1980
- 1980-01-08 SE SE8000110A patent/SE446536B/sv not_active IP Right Cessation
- 1980-01-24 CH CH58280A patent/CH634330A5/de not_active IP Right Cessation
- 1980-01-31 NO NO800239A patent/NO800239L/no unknown
- 1980-03-05 IL IL59527A patent/IL59527A0/xx unknown
- 1980-03-07 FR FR8005220A patent/FR2445834A1/fr active Granted
- 1980-04-18 SE SE8002904A patent/SE8002904L/sv not_active Application Discontinuation
-
1981
- 1981-08-21 US US06/295,074 patent/US4388314A/en not_active Expired - Fee Related
-
1984
- 1984-02-06 SG SG94/84A patent/SG9484G/en unknown
- 1984-07-19 HK HK552/84A patent/HK55284A/xx unknown
-
1985
- 1985-12-30 MY MY446/85A patent/MY8500446A/xx unknown
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