WO2005037779A3 - Neue dipeptidylpeptidase iv-inhibitoren zur funktionellen beeinflussung unterschiedlicher zellen und zur behandlung immunologischer, entzündlicher, neuronaler und anderer erkrankungen - Google Patents

Neue dipeptidylpeptidase iv-inhibitoren zur funktionellen beeinflussung unterschiedlicher zellen und zur behandlung immunologischer, entzündlicher, neuronaler und anderer erkrankungen Download PDF

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Publication number
WO2005037779A3
WO2005037779A3 PCT/EP2004/011645 EP2004011645W WO2005037779A3 WO 2005037779 A3 WO2005037779 A3 WO 2005037779A3 EP 2004011645 W EP2004011645 W EP 2004011645W WO 2005037779 A3 WO2005037779 A3 WO 2005037779A3
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Prior art keywords
diseases
neuronal
inflammatory
different cells
dipeptidyl peptidase
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PCT/EP2004/011645
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English (en)
French (fr)
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WO2005037779A2 (de
Inventor
Siegfried Ansorge
Ute Bank
Karsten Nordhoff
Michael Taeger
Frank Striggow
Original Assignee
Inst Medizintechnologie Magdeb
Keyneurotek Ag
Siegfried Ansorge
Ute Bank
Karsten Nordhoff
Michael Taeger
Frank Striggow
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Application filed by Inst Medizintechnologie Magdeb, Keyneurotek Ag, Siegfried Ansorge, Ute Bank, Karsten Nordhoff, Michael Taeger, Frank Striggow filed Critical Inst Medizintechnologie Magdeb
Priority to CA002542807A priority Critical patent/CA2542807A1/en
Priority to JP2006534708A priority patent/JP2008500270A/ja
Priority to EP04790487A priority patent/EP1675594A2/de
Priority to AU2004281959A priority patent/AU2004281959B9/en
Priority to US10/575,883 priority patent/US20070037785A1/en
Publication of WO2005037779A2 publication Critical patent/WO2005037779A2/de
Publication of WO2005037779A3 publication Critical patent/WO2005037779A3/de

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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Abstract

Die vorliegende Erfindung betrifft Substanzen, die Gly-Pro-p-Nitroanilid spaltende Peptidasen spezifisch inhibieren, für die Verwendung in der Medizin. Weiter betrifft die Erfindung die Verwendung mindestens einer derartigen Substanz oder mindestens einer mindestens eine derartige Substanz enthaltenden pharmazeutischen oder kosmetischen Zusammensetzung zur Prophylaxe und Therapie von Erkrankungen, insbesondere zur Prophylaxe und Therapie von Erkrankungen mit überschiessender Immunantwort (Autoimmunerkrankungen, Allergien und Transplantatrejektionen), von anderen chronisch-entzündlichen Erkrankungen, neuronalen Erkrankungen und zerebralen Schädigungen, Hauterkrankungen (u. a. Akne und Schuppenflechte), Tumorerkrankungen und speziellen Virusinfektionen (u. a. SARS).
PCT/EP2004/011645 2003-10-15 2004-10-15 Neue dipeptidylpeptidase iv-inhibitoren zur funktionellen beeinflussung unterschiedlicher zellen und zur behandlung immunologischer, entzündlicher, neuronaler und anderer erkrankungen WO2005037779A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002542807A CA2542807A1 (en) 2003-10-15 2004-10-15 Novel dipeptidyl peptidase iv inhibitors used for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases
JP2006534708A JP2008500270A (ja) 2003-10-15 2004-10-15 異なるタイプの細胞に機能的に影響を及ぼし、免疫性疾患、炎症性疾患、神経疾患、およびその他の疾患を治療するための新規なジペプチジルペプチダーゼｉｖ阻害剤
EP04790487A EP1675594A2 (de) 2003-10-15 2004-10-15 Neue dipeptidylpeptidase iv-inhibitoren zur funktionellen beeinflussung unterschiedlicher zellen und zur behandlung immunologischer, entzündlicher, neuronaler und anderer erkrankungen
AU2004281959A AU2004281959B9 (en) 2003-10-15 2004-10-15 Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, inflammatory, neuronal, and other diseases
US10/575,883 US20070037785A1 (en) 2003-10-15 2004-10-15 Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10348022.6 2003-10-15
DE10348022A DE10348022A1 (de) 2003-10-15 2003-10-15 Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen

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WO2005037779A2 WO2005037779A2 (de) 2005-04-28
WO2005037779A3 true WO2005037779A3 (de) 2005-07-07

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US20070037785A1 (en) 2007-02-15
JP2008500270A (ja) 2008-01-10

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