WO2003018496A1 - Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung - Google Patents

Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung Download PDF

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Publication number
WO2003018496A1
WO2003018496A1 PCT/EP2002/009220 EP0209220W WO03018496A1 WO 2003018496 A1 WO2003018496 A1 WO 2003018496A1 EP 0209220 W EP0209220 W EP 0209220W WO 03018496 A1 WO03018496 A1 WO 03018496A1
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WO
WIPO (PCT)
Prior art keywords
glass powder
inflammatory
weight
wound healing
glass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/009220
Other languages
German (de)
English (en)
French (fr)
Inventor
Jörg Hinrich FECHNER
José ZIMMER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schott AG
Carl Zeiss AG
Original Assignee
Carl Zeiss AG
Schott Glaswerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10156577A external-priority patent/DE10156577A1/de
Priority claimed from DE10213630A external-priority patent/DE10213630A1/de
Application filed by Carl Zeiss AG, Schott Glaswerke AG filed Critical Carl Zeiss AG
Priority to JP2003523165A priority Critical patent/JP2005501113A/ja
Priority to US10/487,187 priority patent/US7709027B2/en
Priority to EP02772168A priority patent/EP1419118B1/de
Priority to DE50207515T priority patent/DE50207515D1/de
Publication of WO2003018496A1 publication Critical patent/WO2003018496A1/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/062—Glass compositions containing silica with less than 40% silica by weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C12/00—Powdered glass; Bead compositions
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/095—Glass compositions containing silica with 40% to 90% silica, by weight containing rare earths
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/11—Glass compositions containing silica with 40% to 90% silica, by weight containing halogen or nitrogen
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/60—Additives non-macromolecular
    • C09D7/61—Additives non-macromolecular inorganic
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/66—Additives characterised by particle size
    • C09D7/67—Particle size smaller than 100 nm
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/66—Additives characterised by particle size
    • C09D7/68—Particle size between 100-1000 nm
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/66—Additives characterised by particle size
    • C09D7/69—Particle size larger than 1000 nm
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C2204/00—Glasses, glazes or enamels with special properties
    • C03C2204/02—Antibacterial glass, glaze or enamel
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/40—Glass

Definitions

  • the invention relates to an antimicrobial, anti-inflammatory, wound healing glass powder.
  • Anti-inflammatory wound healing glasses are known from the following documents:
  • the anti-inflammatory and wound-healing glasses or glass powder from such glasses all comprise bioactive glasses.
  • the bioactive glass has a significant phosphorus content> 1% by weight.
  • bioactive glass differs from conventional lime-sodium-silicate glasses in that it binds living tissue.
  • Bioactive glass refers to a glass that forms a firm bond with body tissue, forming a layer of hydroxyl apatite.
  • bioactive glasses are the high phosphorus content, which leads to manufacturing problems when the glasses melt. Furthermore, due to their low hydrolytic resistance, the bioactive glasses are only suitable for grinding in aqueous media to a very limited extent
  • the object of the invention is therefore to provide an anti-inflammatory and wound-healing glass powder which is easier to produce than the bioactive glasses or glass powders from such glasses, is toxicologically safe and environmentally friendly.
  • a glass powder is a powder comprising a large number of glass particles of any shape, including glass fibers, for example a glass ball with a particle size of ⁇ 1 mm, preferably ⁇ 500 ⁇ m or a glass fiber with a diameter of ⁇ 1 mm, preferably ⁇ 500 ⁇ m.
  • the glass powder should comprise a glass composition which has a skin-soothing, anti-inflammatory and wound-healing effect against skin irritation, skin irritation, acute and chronic wounds or inflammation, but is toxicologically harmless in contact with humans and in particular is also suitable for consumption.
  • an anti-inflammatory and wound-healing glass powder according to one of claims 1, 4 or 7.
  • the glass of the glass powder can preferably be 20-80% by weight of SiO 2 , 0-40% by weight of Na 2 O, 0-40% by weight of K 2 0.0, 40-40% by weight of Li 2 0.0-40 %
  • B 2 O 3 includes.
  • the sum of Na 2 O + K 2 O + Li 2 O + CaO + MgO is preferably 15 to 80% by weight.
  • the sum Na 2 O + K 2 0 + Li 2 O is particularly preferably 5 to 50% by weight.
  • the sum + CaO + MgO can be 5 to 50% by weight.
  • the glass powder according to the invention can be produced on an industrial scale using standard processes, since the glass composition can be melted on an industrial scale.
  • the glass powders according to the invention can be added to products. Because of their hydrolytic stability, the glass compositions can also be ground into glass powders in aqueous grinding media.
  • the glass powders also have antimicrobial properties.
  • the glasses that are ground to glass powder can be made very pure.
  • the glass powders are then toxicologically safe and suitable for consumption.
  • the exposure to heavy metals is low.
  • the maximum concentration in the range of cosmetic products is preferably for Pb ⁇ 20 ppm, Cd ⁇ 5 ppm, As ⁇ 5 ppm, Sb ⁇ 10 ppm, Hg ⁇ 1 ppm, Ni ⁇ 10 ppm.
  • the anti-inflammatory and wound healing glass powder is particularly skin-friendly.
  • a particular advantage of the glass powder according to the invention is that it comprises a glass which, owing to the melting and hot-shaping behavior, is suitable for being produced in corresponding large-scale plants.
  • the glass powders according to the invention comprising the specified glass composition have an anti-inflammatory and wound-healing effect which can be extremely strong.
  • the smaller the average particle size of the glass powder the higher the anti-inflammatory and wound healing effect due to the increase in the reactive surface of the glass.
  • this anti-inflammatory and wound-healing property is also found in glass powders comprising glasses which, as semi-finished products, have a relatively high hydrolytic resistance. With a small particle size and with a large surface area, however, there is a drastic increase in reactivity, which results in the anti-inflammatory and wound-healing effect due to the ion exchange described below.
  • Glass powder with ion-exchangeable glasses according to the invention have an anti-inflammatory and wound-healing effect in ionic media by ion exchange between a metal ion, such as an alkali or alkaline earth metal ion and the H + ions of the aqueous solution, and by ion-induced impairment of cell growth (osmotic pressure, influencing metabolic processes of the cells).
  • the ground glass powder with particles of small particle size and large surface area show a drastic increase in reactivity, which results in a strong anti-inflammatory and wound-healing effect due to the ion exchange already described.
  • the reason for this is the exchange of ions, which can have an anti-inflammatory effect, for example potassium.
  • the anti-inflammatory effect of the glass powder is surprising to the person skilled in the art, since the glass compositions are largely inert when unmilled. By grinding such a largely inert composition it can be achieved that ions such as K are released in the ground glass powder, which have an anti-inflammatory effect on the epidermis.
  • the glass compositions can be ground to glass powder with particle sizes ⁇ 100 ⁇ m.
  • Particle sizes of ⁇ 50 ⁇ m or 20 ⁇ m have proven to be expedient.
  • Particle sizes ⁇ 10 ⁇ m and smaller than 5 ⁇ m are particularly suitable.
  • Particle sizes ⁇ 2 ⁇ m have proven to be particularly suitable.
  • the grinding process can be carried out dry as well as with aqueous and non-aqueous grinding media. Mixtures of different glass powders from the composition range with different compositions and grain sizes are possible to combine certain effects.
  • pH values of up to 13 are achieved.
  • Mixtures of glass powders with different compositions and grain sizes can be combined synergistically to adjust the special properties of the individual glass powders. For example, it is possible to control the anti-inflammatory and wound healing effect of the glass powder by means of the particle size.
  • the glass of the glass powder contains SiO 2 as a network former, preferably between
  • Na2 ⁇ is used as a flux in. Melting the glass used. at
  • Alkali and alkaline earth oxides can in particular be added in order to increase the ion exchange and. thus reinforcing the anti-inflammatory and wound healing effects.
  • the amount of AI2O3 can increase the chemical resistance of the
  • Crystallization stability and the control of the antimicrobial effect can be added up to a maximum of 8% by weight.
  • B2O3 acts as a network builder and can also be used to control the anti-inflammatory and wound healing effects.
  • ZnO is an essential component for the hot forming properties of the glass. It improves crystallization stability and increases surface tension. It can also support the anti-inflammatory and wound healing effects. With low SiO 2 contents, it increases the
  • Crystallization stability To achieve an anti-inflammatory and wound healing effect, up to 8% by weight of ZnO can be contained.
  • a preferred embodiment contains ⁇ 4% by weight of ZnO or ⁇ 2% by weight. Designs with ⁇ 1% by weight or 0.5% by weight or ⁇ 0.1% by weight are particularly preferred.
  • AgO, CuO can be added as active additives.
  • the glass according to the invention has no skin-irritating effects.
  • a combination of the pH effect and the Ag, Cu or Zn release can achieve a significant increase in the anti-inflammatory and wound-healing effect as well as the additional antimicrobial effect, which goes well beyond the sum of the individual effects.
  • the concentration of Ag, Cu, Zn ions released into the product can be well below 1 ppm.
  • the Ag, Cu, Zn can either be introduced during the melt by appropriate salts or else by ion exchange of the glass after the melt.
  • the glasses can be single or multiple coloring components such as F ⁇ 2 ⁇ 3, CoO, CuO, V2O5. 0 ⁇ 05 in a total concentration of less than 4% by weight, preferably less than 1% by weight.
  • Glass powder with glasses lying within the claimed composition range meet all requirements with regard to use in the areas of paper hygiene, cosmetics, paints, varnishes, cleaning, medical products, cosmetic applications, food additives and use in deodorant products, anti-perspirants and in products for the treatment of skin irritations, acute and chronic wounds.
  • a property of the glass powder is the surprisingly proven skin tolerance, which is also given at high concentrations with high pH values.
  • the glass powder can be used in any suitable form. Mixtures of different glass powders from the composition range with different compositions are also possible. Mixing with other glass powders is also possible to combine certain effects.
  • components such as fluorine can be added to the glass up to a total concentration of 5% by weight.
  • the glass described in this invention from which the glass powder according to the invention is obtained by grinding, is not or hardly water-soluble.
  • the glass powder acts primarily through ion exchange or ion release, which is associated with a surface reaction, pH increase and metal ion release.
  • the glass powders according to the invention have a higher anti-inflammatory and wound healing effect than the group of bioactive glasses described in the prior art or glass powders made from such glasses.
  • FIG 1 shows the regeneration of the barrier function of the epidermis
  • the glass was melted from the raw materials in a silica glass crucible, which was then processed into ribbons.
  • Table 2 shows the compositions and properties of glasses which can be ground to the glass powders according to the invention.
  • the compositions relate to synthesis values in% by weight on an oxide basis.
  • Such glasses show an anti-inflammatory and wound-healing effect after grinding. This is surprising for the person skilled in the art, since glasses with a phosphorus content of less than 1% by weight based on oxide, for example soda-lime glasses as glass, are largely unreactive. An anti-inflammatory effect was only attributed to phosphorus-containing glasses with a phosphorus content> 1% by weight, since these glasses are considered to be very reactive.
  • All glasses in particular the suitable glasses in the composition specified above, can contain trace elements and / or customary refining agents in customary amounts.
  • Trace elements are, for example, impurities contained in the glass such as Fe 2 ⁇ 3 or K 2 0; usual refining agents AS 2 O 3 ,
  • mice have shown that the anti-inflammatory and wound healing properties are superior to bioactive glasses.
  • the active substances A.1, V.1, V.2 and V.3 investigated as glass powder were applied in a quantity of 10% by weight in a DAC base cream.
  • a DAC base cream without active substance was also applied.
  • FIG. 1 shows the course of the repair of a superficial wound, ie the regeneration of the barrier function of the epidermis, measured via the transepidermal water loss.
  • the superficial wound was preserved by pre-damage with tape stripping.
  • Tape stripping refers to the damage to the uppermost layers of the skin caused by the application and removal of adhesive strips. It can be seen in FIG. 1 that the regeneration of the skin's barrier function after 24 hours is about 10% better with a glass powder with a glass composition according to the invention than with the bioactive glass powder V.1.
  • the bioactive glass powders V.2 and V.3 as well as the DAC cream without active ingredient as comparison samples show an even lower regeneration of the barrier function.
  • the anti-inflammatory and wound healing glass memevers can be used as a food additive, in cosmetic products and deoproducts, in particular to reduce skin irritation, but not limited to it, in medical products, in particular products for wound care and treatment, plastics and polymers, paper hygiene, in paints, varnishes and in Detergents are used.

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Glass Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paints Or Removers (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Materials For Medical Uses (AREA)
PCT/EP2002/009220 2001-08-22 2002-08-17 Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung Ceased WO2003018496A1 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003523165A JP2005501113A (ja) 2001-08-22 2002-08-17 炎症を抑えて傷を癒す抗菌性のガラス粉末ならびにその使用方法
US10/487,187 US7709027B2 (en) 2001-08-22 2002-08-17 Antimicrobial, anti-inflammatory, wound-healing glass powder and use thereof
EP02772168A EP1419118B1 (de) 2001-08-22 2002-08-17 Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung
DE50207515T DE50207515D1 (de) 2001-08-22 2002-08-17 Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE10141116 2001-08-22
DE10141116.2 2001-08-22
DE10156577.1 2001-11-20
DE10156577A DE10156577A1 (de) 2001-11-20 2001-11-20 Antimikrobielles, entzündungshemmendes, wundheilendes und desinfizierendes Glas und dessen Verwendung
DE10213630A DE10213630A1 (de) 2001-08-22 2002-03-27 Antimikrobielles Glas und dessen Verwendung
DE10213630.0 2002-03-27
DE10213632A DE10213632A1 (de) 2001-08-22 2002-03-27 Antimikrobielles, entzündungshemmendes, wundheilendes Glas und dessen Verwendung
DE10213632.7 2002-03-27

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Publication Number Publication Date
WO2003018496A1 true WO2003018496A1 (de) 2003-03-06

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PCT/EP2002/009220 Ceased WO2003018496A1 (de) 2001-08-22 2002-08-17 Antimikrobielles, entzündungshemmendes, wundheilendes glaspulver und dessen verwendung

Country Status (6)

Country Link
US (1) US7709027B2 (enExample)
EP (1) EP1419118B1 (enExample)
JP (1) JP2005501113A (enExample)
AT (1) ATE332879T1 (enExample)
DE (1) DE50207515D1 (enExample)
WO (1) WO2003018496A1 (enExample)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082358A1 (de) * 2002-03-28 2003-10-09 Schott Glas Verwendung von glas- und/oder glaskeramikpulver oder -fasern zur kontrollierten ionenabgabe
WO2004076369A3 (de) * 2003-02-25 2005-03-31 Schott Ag Antimikrobiell wirkendes brosilicatglas
GB2407812A (en) * 2003-10-14 2005-05-11 Pentax Corp CaO-MgO-SiO2 based bioactive glass and sintered calcium phosphate glass using same
DE102004023732A1 (de) * 2004-05-11 2005-12-08 Schott Ag Verwendungen von siliciumhaltigen und phosphorfreien Gläsern zur Behandlung entzündlicher Erkrankungen
JP2007507426A (ja) * 2003-09-29 2007-03-29 ショット アクチエンゲゼルシャフト 組織研磨剤
US7332452B2 (en) 2002-07-15 2008-02-19 Pentax Corporation CaO-SiO2-based bioactive glass and sintered calcium phosphate using same
EP2189426A1 (de) 2004-05-29 2010-05-26 Schott AG Verfahren zur Herstellung eines Glas- oder Glaskeramikpulvers in Form von Nanopartikeln
EP2243500A1 (en) 2009-04-23 2010-10-27 Vivoxid Oy Biocompatible composite and its use
EP2243749A1 (en) 2009-04-23 2010-10-27 Vivoxid Oy Resorbable and biocompatible fibre glass compositions and their uses

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112004000094A5 (de) * 2003-02-25 2008-04-03 Schott Ag Antimikrobiell wirkendes Borosilicatglas
US8080490B2 (en) 2003-02-25 2011-12-20 Schott Ag Antimicrobial phosphate glass
DE10316156B3 (de) * 2003-04-09 2004-10-14 Beiersdorf Ag Antimikrobiell ausgerüstete Polymermaterialien und deren Verwendung als Wundauflage
DE102004026432A1 (de) * 2004-05-29 2005-12-22 Schott Ag Glaszusammensetzungen als antimikrobieller Zusatz für Dentalmaterialien und deren Verwendung
DE102005001078A1 (de) * 2005-01-08 2006-07-20 Schott Ag Glaspulver, insbesondere biologisch aktives Glaspulver und Verfahren zur Herstellung von Glaspulver, insbesondere biologisch aktivem Glaspulver
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
ES2507070T3 (es) 2006-02-03 2014-10-14 Omp, Inc. Tratamiento antienvejecimiento utilizando composiciones de cobre y zinc
GB0612028D0 (en) * 2006-06-16 2006-07-26 Imp Innovations Ltd Bioactive glass
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
CA2667715C (en) * 2006-11-28 2015-03-31 The Morgan Crucible Company Plc Inorganic fibre compositions
JP5014762B2 (ja) * 2006-12-13 2012-08-29 日本化学工業株式会社 防錆顔料及びこれを含有する防錆塗料組成物
CN101426938B (zh) * 2007-01-31 2010-06-02 中国科学院过程工程研究所 一种钢材防氧化涂料及钢材的防氧化方法
GB0724896D0 (en) * 2007-12-20 2008-01-30 Imp Innovations Ltd Bioactive Glass coatings
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
EP2293738A2 (en) * 2008-05-27 2011-03-16 Imperial Innovations Limited Process for producing porous scaffolds from sinterable glass
GB0809592D0 (en) * 2008-05-27 2008-07-02 Imp Innovations Ltd Biomaterials
JP2010059039A (ja) * 2008-08-05 2010-03-18 Central Glass Co Ltd 薄片状物質及び塗料組成物
RU2395548C1 (ru) * 2008-12-24 2010-07-27 Сергей Константинович Евстропьев Бактерицидное оксидное покрытие и способ его получения
WO2010085753A1 (en) 2009-01-23 2010-07-29 Jr Chem, Llc Rosacea treatments and kits for performing them
GB0911365D0 (en) 2009-06-30 2009-08-12 Bioceramic Therapeutics Ltd Multicomponent glasses for use as coatings and in personal care products
US8481066B2 (en) 2009-07-16 2013-07-09 The Curators Of The University Of Missouri Scaffold for tissue regeneration in mammals
US8287896B2 (en) * 2010-01-06 2012-10-16 The Curators Of The University Of Missouri Scaffolds with trace element for tissue regeneration in mammals
US9556059B2 (en) * 2009-08-03 2017-01-31 Hong Li Glass compositions and fibers made therefrom
US9593038B2 (en) 2009-08-03 2017-03-14 Ppg Industries Ohio, Inc. Glass compositions and fibers made therefrom
US9446983B2 (en) 2009-08-03 2016-09-20 Ppg Industries Ohio, Inc. Glass compositions and fibers made therefrom
US8173154B2 (en) * 2010-01-06 2012-05-08 The Curators Of The University Of Missouri Boron trioxide glass-based fibers and particles in dressings, sutures, surgical glue, and other wound care compositions
RU2432327C1 (ru) * 2010-05-20 2011-10-27 Юлия Алексеевна Щепочкина Стекло для изготовления бисера
WO2012068269A2 (en) 2010-11-16 2012-05-24 Unifrax I Llc Inorganic fiber
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
JP6038117B2 (ja) 2011-03-28 2016-12-07 コーニング インコーポレイテッド ガラス表面上のＣｕ、ＣｕＯおよびＣｕ２Ｏナノ粒子の抗微生物作用および耐久性被覆
US8821919B2 (en) 2012-05-18 2014-09-02 Mo/Sci Corporation Wound debridement
WO2014152727A1 (en) 2013-03-15 2014-09-25 Unifrax I Llc Inorganic fiber
US9622483B2 (en) 2014-02-19 2017-04-18 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039620B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039621B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
BR122022004023B1 (pt) 2014-07-16 2022-12-27 Unifrax I Llc Fibra inorgânica com retratibilidade e resistência aumentadas
US10023491B2 (en) 2014-07-16 2018-07-17 Unifrax I Llc Inorganic fiber
ES2779924T3 (es) 2014-07-17 2020-08-20 Unifrax I Llc Fibra inorgánica con contracción y resistencia mejoradas
WO2016089731A1 (en) * 2014-12-04 2016-06-09 3M Innovative Properties Company Antimicrobial compositions comprising bioglass
CN107001122A (zh) * 2014-12-11 2017-08-01 日本电气硝子株式会社 创伤治疗用玻璃组合物、创伤覆盖材料及其制造方法
US10064273B2 (en) 2015-10-20 2018-08-28 MR Label Company Antimicrobial copper sheet overlays and related methods for making and using
JP2017114722A (ja) * 2015-12-24 2017-06-29 日本電気硝子株式会社 創傷被覆材
US9919957B2 (en) 2016-01-19 2018-03-20 Unifrax I Llc Inorganic fiber
US20170342383A1 (en) 2016-05-27 2017-11-30 Corning Incorporated Lithium disilicate glass-ceramic compositions and methods thereof
US10647962B2 (en) 2016-05-27 2020-05-12 Corning Incorporated Bioactive aluminoborate glasses
US10751367B2 (en) 2016-05-27 2020-08-25 Corning Incorporated Bioactive glass microspheres
US10676713B2 (en) 2016-05-27 2020-06-09 Corning Incorporated Bioactive borophosphate glasses
EP3717030A1 (en) 2017-11-28 2020-10-07 Corning Incorporated Bioactive glass compositions and dentin hypersensitivity remediation
EP3717428A1 (en) 2017-11-28 2020-10-07 Corning Incorporated Bioactive borate glass and methods thereof
EP3717427A1 (en) * 2017-11-28 2020-10-07 Corning Incorporated High liquidus viscosity bioactive glass
CN111417601A (zh) 2017-11-28 2020-07-14 康宁股份有限公司 化学强化的生物活性玻璃陶瓷
US10882779B2 (en) 2018-05-25 2021-01-05 Unifrax I Llc Inorganic fiber
NZ774059A (en) 2018-09-05 2025-11-28 Ir Scient Inc Glass composition
WO2020112404A1 (en) * 2018-11-26 2020-06-04 Corning Incorporated Bioactive silicate glasses
KR102498534B1 (ko) * 2019-09-02 2023-02-10 엘지전자 주식회사 항균 유리 조성물 및 항균 유리의 제조방법
KR102536734B1 (ko) * 2020-01-17 2023-05-24 엘지전자 주식회사 항균 글라스 조성물 및 이의 제조방법
KR102545212B1 (ko) * 2020-02-17 2023-06-19 엘지전자 주식회사 비용출성 항균 유리 조성물 및 이를 이용한 항균 유리 분말 제조 방법
KR102456475B1 (ko) * 2020-02-26 2022-10-18 엘지전자 주식회사 세탁 및 세척용 복합 유리 조성물 및 이를 이용한 복합 유리 분말 제조 방법
KR102812177B1 (ko) * 2022-03-03 2025-05-22 엘지전자 주식회사 세제용 유리 조성물 및 이를 이용한 세제용 유리 분말 제조 방법

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0425927A1 (de) * 1989-11-01 1991-05-08 Bayer Ag Emailfritten mit verbesserter Haftung für Stahlblech
JPH03146436A (ja) * 1989-11-01 1991-06-21 U H I Syst Kk 抗菌・殺菌用ガラス
US5074916A (en) 1990-05-18 1991-12-24 Geltech, Inc. Alkali-free bioactive sol-gel compositions
JPH0725635A (ja) * 1993-07-09 1995-01-27 Nippon Glass Fiber Co Ltd 抗菌性を有するフレーク状ガラス
WO1996021628A1 (en) * 1995-01-13 1996-07-18 Maria Brink Novel bioactive glasses and their use
US5834008A (en) 1996-09-19 1998-11-10 U.S. Biomaterials Corp. Composition and method for acceleration of wound and burn healing
EP0921105A1 (en) * 1997-12-02 1999-06-09 Esmaltes, S.A. Bactericidal ceramic enamel and uses thereof
JPH11209143A (ja) * 1998-01-23 1999-08-03 Ishizuka Glass Co Ltd 抗菌性ガラス繊維
JPH11228173A (ja) * 1998-02-18 1999-08-24 Nippon Electric Glass Co Ltd 抗菌性ガラス及び樹脂組成物
WO2000015167A1 (en) 1998-09-10 2000-03-23 Usbiomaterials Corporation Anti-inflammatory and antimicrobial uses for bioactive glass compositions
WO2000066086A1 (en) 1999-04-29 2000-11-09 Usbiomaterials Corporation Anti-inflammatory bioactive glass particulates
WO2000076486A1 (en) * 1999-06-14 2000-12-21 Imperial College Innnovations Silver-containing, sol-gel derived bioglass compositions

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1294337A (en) 1969-11-05 1972-10-25 Arthur Terence Ranson Process for treating glass
GB1316160A (en) 1970-10-15 1973-05-09 Hollandsche Betongroep Nv Concrete reinforcement
JPS5116446B1 (enExample) * 1971-05-21 1976-05-24
JPS5138727B1 (enExample) * 1971-07-23 1976-10-23
US3926246A (en) * 1972-09-18 1975-12-16 Scm Corp Flux for continuous casting of steel
US4092139A (en) * 1977-03-16 1978-05-30 Corning Glass Works Process for making colored photosensitive glass
GB8327949D0 (en) 1983-10-19 1983-11-23 Holmes A Glass ceramic materials
JPS61133813A (ja) 1984-12-03 1986-06-21 Matsushita Electric Ind Co Ltd 面形状測定装置
JPS61186248A (ja) * 1985-02-13 1986-08-19 Nippon Electric Glass Co Ltd ガラスセラミツク
GB2178422B (en) 1985-08-02 1990-02-14 Stc Plc Prosthesis formed from water-soluble phosphate glass.
EP0220333B1 (de) * 1985-10-26 1990-03-21 Schott Glaswerke Durchsichtige farbige Glaskeramik mit guter Temperaturbelastbarkeit und variabel einstellbarer Transmission im IR-Bereich
JPH02149447A (ja) 1988-12-01 1990-06-08 Nippon Electric Glass Co Ltd 歯科用結晶化ガラス
US5196381A (en) * 1990-01-16 1993-03-23 E. I. Du Pont De Nemours And Company Metaphosphate glass composition
US5022921A (en) * 1990-10-19 1991-06-11 Corning Incorporated Phosphate glasses for glass molds
JP3146436B2 (ja) 1990-10-30 2001-03-19 日立マクセル株式会社 Ｉｃモジユール
US6123743A (en) * 1991-01-07 2000-09-26 Norton Company Glass-ceramic bonded abrasive tools
JP3057773B2 (ja) * 1991-02-05 2000-07-04 不二製油株式会社 パイの製造方法
JPH0788236B2 (ja) 1991-05-10 1995-09-27 石塚硝子株式会社 合成樹脂添加用硝子組成物
US5234871A (en) * 1991-11-27 1993-08-10 Schott Glass Technologies, Inc. Vanadium- and copper-containing glasses for use as filters for light sources intended for use with night vision devices
JPH06340445A (ja) * 1993-05-28 1994-12-13 Kirin Brewery Co Ltd 黄色着色ガラス
US5807641A (en) * 1993-05-31 1998-09-15 Sumitomo Osaka Cement Co., Ltd. Anti-bacterial and anti-fungal glaze composition for ceramic products
JPH0726635A (ja) 1993-07-09 1995-01-27 Hirobumi Furukawa アングル枠構造物の組立法
JP3428080B2 (ja) 1993-08-05 2003-07-22 日本板硝子株式会社 銀イオン含有ガラスの製造方法
US5328874A (en) * 1993-10-18 1994-07-12 Corning Incorporated Zinc sulfophosphate glasses
JPH07291654A (ja) 1994-04-22 1995-11-07 Nippon Sheet Glass Co Ltd 抗菌性ガラス粉末
DE19503167A1 (de) 1995-02-01 1996-08-08 Gruenzweig & Hartmann Glasfaserzusammensetzungen
JPH0848539A (ja) 1994-06-02 1996-02-20 Nippon Sheet Glass Co Ltd 抗菌性ガラス組成物
JP3110963B2 (ja) 1994-12-20 2000-11-20 石塚硝子株式会社 耐久性を有する抗菌剤
GB9502253D0 (en) * 1995-02-06 1995-03-29 Giltech Ltd The effects of antibacterial agents on the behaviour of mouse fibroblasts in vitro
JP3026732B2 (ja) 1995-02-08 2000-03-27 神鋼パンテツク株式会社 抗菌性を有するガラス被覆の施工方法
JPH08245240A (ja) 1995-03-06 1996-09-24 Koa Glass Kk 抗菌性複合ガラス粒子
DE69613941T2 (de) 1995-11-06 2001-11-22 Corning Inc., Corning Dreikomponenten-Glas-/Polymer-Mischungen
HUP9901760A3 (en) 1996-01-29 1999-11-29 Usbiomaterials Corp Alachua Bioactive glass compositions and methods of treatment using bioactive glass
CN1130451C (zh) * 1996-03-22 2003-12-10 普罗格特-甘布尔公司 含有载负释放抑制剂的沸石的输送体系和制备该输送体系的方法
JPH1059788A (ja) 1996-08-21 1998-03-03 Tokyo Yogyo Co Ltd 抗菌器具
JP3772414B2 (ja) 1996-09-26 2006-05-10 旭硝子株式会社 有機樹脂に燃焼時の発煙抑止機能を付与する低融点ガラス
US6074984A (en) * 1996-11-18 2000-06-13 Bulldog Technologies U.S.A., Inc. SOx Additive systems based upon use of multiple particle species
JPH10158037A (ja) 1996-11-27 1998-06-16 Asahi Glass Co Ltd 抗菌性ガラス及びその製造方法
JPH10218637A (ja) 1997-01-31 1998-08-18 Nippon Glass Fiber Co Ltd 抗菌・抗かび性ガラス及びそのガラスを含有する樹脂組成物
JPH10231187A (ja) 1997-02-21 1998-09-02 Toto Ltd 抗菌性釉薬、この釉薬を用いた陶磁器製品及び抗菌性釉薬の調製方法
ATE307620T1 (de) 1997-04-05 2005-11-15 Tyco Healthcare Implantatmaterial mit glaspartikeln
JP3845959B2 (ja) 1997-07-07 2006-11-15 日本電気硝子株式会社 抗菌性ガラス粉末及び樹脂成形体
JPH1160277A (ja) 1997-08-18 1999-03-02 Nippon Electric Glass Co Ltd 抗菌性結晶化ガラス物品及びその製造方法
US6360562B1 (en) * 1998-02-24 2002-03-26 Superior Micropowders Llc Methods for producing glass powders
JPH11278866A (ja) 1998-03-31 1999-10-12 Nihon Yamamura Glass Co Ltd ガラス容器の抗菌処理方法
US6509057B2 (en) * 1998-04-01 2003-01-21 Sumitomo Osaka Cement, Co., Ltd. Antibacterial, antifungal or antialgal article and process for producing same
JP3453515B2 (ja) 1998-05-12 2003-10-06 東洋佐々木ガラス株式会社 抗菌性強化ガラス物品
JP2000053451A (ja) 1998-08-05 2000-02-22 Sumitomo Osaka Cement Co Ltd 抗菌性ガラス製品およびその製造方法
JP2000191339A (ja) 1998-12-28 2000-07-11 Koa Glass Kk 溶解性ガラス、抗菌性樹脂組成物、および抗菌性成形品
JP2000203876A (ja) 1998-12-28 2000-07-25 Nippon Sheet Glass Co Ltd 抗菌性ガラス及びそのガラスを含有する樹脂組成物
WO2000038552A1 (en) 1998-12-31 2000-07-06 Healthshield Technologies Llc Antimicrobial contact lens case
GB9904557D0 (en) 1999-02-26 1999-04-21 Gillette Co Deodorant compositions
JP2000264674A (ja) 1999-03-12 2000-09-26 Nippon Sheet Glass Co Ltd 抗菌性ガラス及び樹脂組成物
JP2001048595A (ja) 1999-03-19 2001-02-20 Inax Corp ガラス層をもつ基体の表面処理方法及びその製品
JP2000327369A (ja) 1999-05-21 2000-11-28 Asahi Glass Co Ltd リン酸スズ系ガラス含有結晶性組成物
IL147305A0 (en) 1999-07-09 2002-08-14 Zeiss Stiftung Preservatives containing bioactive glass
JP2001026466A (ja) 1999-07-13 2001-01-30 Nippon Sheet Glass Co Ltd 抗菌ガラスの製造方法
DE19960548A1 (de) * 1999-12-15 2001-06-21 Siemens Ag Glas/Kunststoff-Compounds
JP2001247333A (ja) 1999-12-28 2001-09-11 Ishizuka Glass Co Ltd 抗菌性付与用ガラス組成物、抗菌性繊維、抗菌性撚糸及び抗菌性布状物
JP4689019B2 (ja) 1999-12-28 2011-05-25 石塚硝子株式会社 抗菌性付与用ガラス組成物、及びそれを用いた抗菌性高分子複合材料、抗菌性高分子複合材料成形体
JP2001247335A (ja) 1999-12-28 2001-09-11 Ishizuka Glass Co Ltd 抗菌性付与用ガラス組成物、抗菌性高分子複合材料及び抗菌性繊維
JP2001247334A (ja) 1999-12-28 2001-09-11 Ishizuka Glass Co Ltd 抗菌性付与用ガラス組成物及び抗菌性繊維
JP2001247336A (ja) * 1999-12-28 2001-09-11 Ishizuka Glass Co Ltd 抗菌性付与用ガラス組成物、及びそれを用いた抗菌性高分子複合材料、抗菌性高分子複合材料成形体
WO2001051426A1 (en) 2000-01-14 2001-07-19 Inax Corporation Product having glass layer and method for assessing the same
KR20030019333A (ko) * 2000-03-27 2003-03-06 쇼트 그라스 신규 화장품, 퍼스널 케어, 클리닝제, 및 생체활성 유리를포함하는 영양 보충 조성물 및 이의 제조방법과 용법
DE10017701C2 (de) * 2000-04-08 2002-03-07 Schott Glas Gefloatetes Flachglas
CN1323527A (zh) 2000-05-16 2001-11-28 顾浩 银、铜无机抗菌剂
JP2002012442A (ja) 2000-06-23 2002-01-15 Asahi Glass Co Ltd 低融点ガラス
CN1202034C (zh) * 2000-09-29 2005-05-18 兴亚硝子株式会社 抗菌性玻璃及其制造方法
US20040166172A1 (en) * 2001-03-27 2004-08-26 Coni Rosati Bioctive tissue abrasives
DE10122262A1 (de) * 2001-05-08 2002-11-21 Schott Glas Polymere mit bioaktivem Glas mit antimikrobieller Wirkung
DE10141117A1 (de) * 2001-08-22 2003-03-13 Schott Glas Antimikrobielles Silicatglas und dessen Verwendung
WO2003018498A1 (de) * 2001-08-22 2003-03-06 Schott Glas Antimikrobielles, entzündungshemmendes, wundheilendes und desinfizierendes glas und dessen verwendung
JP4052836B2 (ja) 2002-01-15 2008-02-27 日本電気硝子株式会社 抗菌性ガラス微小球及びその製造方法
US20050119105A1 (en) * 2002-01-18 2005-06-02 Schott Ag Glass-ceramic composite containing nanoparticles
CN1379146A (zh) 2002-05-20 2002-11-13 朱红军 复合型(Ag+Ag2O)防集聚纳米银抗菌非织造布及工业化生产工艺
US6921546B2 (en) 2003-02-20 2005-07-26 Gemtron Corporation Antimicrobial glass and glass-like products and method of preparing same
DE10308227A1 (de) * 2003-02-25 2004-09-09 Schott Glas Antimikrobiell wirkendes Sulfophosphatglas
JP2006520311A (ja) 2003-02-25 2006-09-07 ショット アクチエンゲゼルシャフト 抗微生物作用ホウケイ酸ガラス
DE112004000094A5 (de) * 2003-02-25 2008-04-03 Schott Ag Antimikrobiell wirkendes Borosilicatglas
US8080490B2 (en) 2003-02-25 2011-12-20 Schott Ag Antimicrobial phosphate glass
DE10309826B4 (de) * 2003-03-05 2009-11-12 Schott Ag Verfahren zum Strukturieren von Phosphatgläsern durch zerstörungsfreien Ionenaustausch, strukturierte Phosphatgläser und deren Verwendung
JP4338129B2 (ja) 2003-09-12 2009-10-07 フジノン株式会社 超音波内視鏡
DE102004011520A1 (de) * 2004-03-08 2005-10-06 Schott Ag Antimikrobiell brechzahlangepasstes Phosphatglas
DE102004026432A1 (de) * 2004-05-29 2005-12-22 Schott Ag Glaszusammensetzungen als antimikrobieller Zusatz für Dentalmaterialien und deren Verwendung

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0425927A1 (de) * 1989-11-01 1991-05-08 Bayer Ag Emailfritten mit verbesserter Haftung für Stahlblech
JPH03146436A (ja) * 1989-11-01 1991-06-21 U H I Syst Kk 抗菌・殺菌用ガラス
US5074916A (en) 1990-05-18 1991-12-24 Geltech, Inc. Alkali-free bioactive sol-gel compositions
JPH0725635A (ja) * 1993-07-09 1995-01-27 Nippon Glass Fiber Co Ltd 抗菌性を有するフレーク状ガラス
WO1996021628A1 (en) * 1995-01-13 1996-07-18 Maria Brink Novel bioactive glasses and their use
US5834008A (en) 1996-09-19 1998-11-10 U.S. Biomaterials Corp. Composition and method for acceleration of wound and burn healing
EP0921105A1 (en) * 1997-12-02 1999-06-09 Esmaltes, S.A. Bactericidal ceramic enamel and uses thereof
JPH11209143A (ja) * 1998-01-23 1999-08-03 Ishizuka Glass Co Ltd 抗菌性ガラス繊維
JPH11228173A (ja) * 1998-02-18 1999-08-24 Nippon Electric Glass Co Ltd 抗菌性ガラス及び樹脂組成物
WO2000015167A1 (en) 1998-09-10 2000-03-23 Usbiomaterials Corporation Anti-inflammatory and antimicrobial uses for bioactive glass compositions
WO2000066086A1 (en) 1999-04-29 2000-11-09 Usbiomaterials Corporation Anti-inflammatory bioactive glass particulates
WO2000076486A1 (en) * 1999-06-14 2000-12-21 Imperial College Innnovations Silver-containing, sol-gel derived bioglass compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 015, no. 369 (C - 0868) 18 September 1991 (1991-09-18) *
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 13 30 November 1999 (1999-11-30) *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082358A1 (de) * 2002-03-28 2003-10-09 Schott Glas Verwendung von glas- und/oder glaskeramikpulver oder -fasern zur kontrollierten ionenabgabe
US7332452B2 (en) 2002-07-15 2008-02-19 Pentax Corporation CaO-SiO2-based bioactive glass and sintered calcium phosphate using same
WO2004076369A3 (de) * 2003-02-25 2005-03-31 Schott Ag Antimikrobiell wirkendes brosilicatglas
JP2007507426A (ja) * 2003-09-29 2007-03-29 ショット アクチエンゲゼルシャフト 組織研磨剤
GB2407812A (en) * 2003-10-14 2005-05-11 Pentax Corp CaO-MgO-SiO2 based bioactive glass and sintered calcium phosphate glass using same
US7214635B2 (en) 2003-10-14 2007-05-08 Pentax Corporation CaO-MgO-SiO2-based bioactive glass and sintered calcium phosphate glass using same
DE102004023732A1 (de) * 2004-05-11 2005-12-08 Schott Ag Verwendungen von siliciumhaltigen und phosphorfreien Gläsern zur Behandlung entzündlicher Erkrankungen
EP2189426A1 (de) 2004-05-29 2010-05-26 Schott AG Verfahren zur Herstellung eines Glas- oder Glaskeramikpulvers in Form von Nanopartikeln
US7816292B2 (en) 2004-05-29 2010-10-19 Schott Ag Nano glass powder and use thereof, in particular multicomponent glass powder with a mean particle size of less than 1 μm
EP2243500A1 (en) 2009-04-23 2010-10-27 Vivoxid Oy Biocompatible composite and its use
EP2243749A1 (en) 2009-04-23 2010-10-27 Vivoxid Oy Resorbable and biocompatible fibre glass compositions and their uses
WO2010122098A2 (en) 2009-04-23 2010-10-28 Vivoxid Oy Biocompatible composite and its use
WO2010122019A1 (en) 2009-04-23 2010-10-28 Vivoxid Oy Resorbable and biocompatible fibre glass compositions and their uses

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US7709027B2 (en) 2010-05-04
EP1419118B1 (de) 2006-07-12
JP2005501113A (ja) 2005-01-13
DE50207515D1 (de) 2006-08-24
US20040253321A1 (en) 2004-12-16
ATE332879T1 (de) 2006-08-15
EP1419118A1 (de) 2004-05-19

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