WO2002030495A3 - Dispositif du type stylo pour l'administration d'hormone parathyroide - Google Patents

Dispositif du type stylo pour l'administration d'hormone parathyroide Download PDF

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Publication number
WO2002030495A3
WO2002030495A3 PCT/US2001/027732 US0127732W WO0230495A3 WO 2002030495 A3 WO2002030495 A3 WO 2002030495A3 US 0127732 W US0127732 W US 0127732W WO 0230495 A3 WO0230495 A3 WO 0230495A3
Authority
WO
WIPO (PCT)
Prior art keywords
dose
parathyroid hormone
priming
administration
pen device
Prior art date
Application number
PCT/US2001/027732
Other languages
English (en)
Other versions
WO2002030495A2 (fr
Inventor
Michael Joseph Roe
Original Assignee
Lilly Co Eli
Michael Joseph Roe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE60122186T priority Critical patent/DE60122186T2/de
Priority to AU2001292581A priority patent/AU2001292581B2/en
Priority to IL15468301A priority patent/IL154683A0/xx
Priority to US10/381,097 priority patent/US20040097883A1/en
Priority to BR0114498-7A priority patent/BR0114498A/pt
Priority to EP01972950A priority patent/EP1326664B1/fr
Priority to CA002424015A priority patent/CA2424015A1/fr
Priority to EA200300446A priority patent/EA004406B1/ru
Application filed by Lilly Co Eli, Michael Joseph Roe filed Critical Lilly Co Eli
Priority to MXPA03002993A priority patent/MXPA03002993A/es
Priority to AU9258101A priority patent/AU9258101A/xx
Priority to JP2002533933A priority patent/JP4897185B2/ja
Priority to PL360881A priority patent/PL197463B1/pl
Priority to KR1020037004947A priority patent/KR100782606B1/ko
Publication of WO2002030495A2 publication Critical patent/WO2002030495A2/fr
Publication of WO2002030495A3 publication Critical patent/WO2002030495A3/fr
Priority to NO20031044A priority patent/NO330570B1/no
Priority to CY20061101506T priority patent/CY1106210T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/585—Means for facilitating use, e.g. by people with impaired vision by visual feedback having magnification means, e.g. magnifying glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M5/31538—Permanent blocking, e.g. by medical personnel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member

Abstract

Cette invention a trait à un dispositif distributeur, du type stylo, ainsi qu'au procédé correspondant, d'administration d'hormone parathyroïde, permettant l'amorçage et l'injection d'une dose unique prédéterminée. Ce procédé, qui comporte trois étapes, utilise des indicateurs visuels permettant d'adapter l'administration des doses d'amorce et d'injection. Le dispositif selon l'invention, qui comporte un minimum de pièces, est constitué d'un logement, d'un bouton doseur, d'un ensemble de désolidarisation généralement cylindrique placé dans l'extrémité proximale du bouton doseur et d'une tige de commande filetée extérieurement. Ce dispositif distributeur, du type stylo, est doté d'un mécanisme évitant que son utilisateur ne sélectionne un dosage supérieur à celui qui reste dans la cartouche.
PCT/US2001/027732 2000-10-09 2001-09-26 Dispositif du type stylo pour l'administration d'hormone parathyroide WO2002030495A2 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
MXPA03002993A MXPA03002993A (es) 2000-10-09 2001-09-26 Dispositivo en forma de pluma para administracion de hormona paratiroides.
AU2001292581A AU2001292581B2 (en) 2000-10-09 2001-09-26 Pen device for administration of parathyroid hormone
AU9258101A AU9258101A (en) 2000-10-09 2001-09-26 Pen device for administration of parathyroid hormone
BR0114498-7A BR0114498A (pt) 2000-10-09 2001-09-26 Dispositivo de administração tipo caneta, e, método de usar um dispositivo de administração tipo caneta.
EP01972950A EP1326664B1 (fr) 2000-10-09 2001-09-26 Dispositif du type stylo pour l'administration d'hormone parathyroide
CA002424015A CA2424015A1 (fr) 2000-10-09 2001-09-26 Dispositif du type stylo pour l'administration d'hormone parathyroide
EA200300446A EA004406B1 (ru) 2000-10-09 2001-09-26 Устройство типа ручки для введения паратиреоидного гормона
DE60122186T DE60122186T2 (de) 2000-10-09 2001-09-26 Stiftvorrichtung zur verabreichung des parathyroid-hormons
IL15468301A IL154683A0 (en) 2000-10-09 2001-09-26 Pen device for administration of parathyroid hormone
US10/381,097 US20040097883A1 (en) 2000-10-09 2001-09-26 Pen device for administration of parathyroid hormone
JP2002533933A JP4897185B2 (ja) 2000-10-09 2001-09-26 副甲状線ホルモン投与のためのペン装置
PL360881A PL197463B1 (pl) 2000-10-09 2001-09-26 Pen dozujący
KR1020037004947A KR100782606B1 (ko) 2000-10-09 2001-09-26 부갑상선 호르몬 투약을 위한 펜 장치
NO20031044A NO330570B1 (no) 2000-10-09 2003-03-06 Penninnretning for administrering av paratyroidhormon
CY20061101506T CY1106210T1 (el) 2000-10-09 2006-10-20 Συσκευη τυπου πεννας για την χορηγηση παραθυρεοειδικης ορμονης

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23917200P 2000-10-09 2000-10-09
US60/239,172 2000-10-09

Publications (2)

Publication Number Publication Date
WO2002030495A2 WO2002030495A2 (fr) 2002-04-18
WO2002030495A3 true WO2002030495A3 (fr) 2002-07-04

Family

ID=22900927

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/027732 WO2002030495A2 (fr) 2000-10-09 2001-09-26 Dispositif du type stylo pour l'administration d'hormone parathyroide

Country Status (22)

Country Link
US (1) US20040097883A1 (fr)
EP (1) EP1326664B1 (fr)
JP (1) JP4897185B2 (fr)
KR (1) KR100782606B1 (fr)
CN (1) CN1268405C (fr)
AT (1) ATE335519T1 (fr)
AU (2) AU2001292581B2 (fr)
BR (1) BR0114498A (fr)
CA (1) CA2424015A1 (fr)
CY (1) CY1106210T1 (fr)
DE (1) DE60122186T2 (fr)
DK (1) DK1326664T3 (fr)
EA (1) EA004406B1 (fr)
ES (1) ES2267820T3 (fr)
IL (1) IL154683A0 (fr)
MX (1) MXPA03002993A (fr)
NO (1) NO330570B1 (fr)
NZ (1) NZ539404A (fr)
PL (1) PL197463B1 (fr)
PT (1) PT1326664E (fr)
WO (1) WO2002030495A2 (fr)
ZA (1) ZA200301758B (fr)

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US8905971B2 (en) 2005-12-02 2014-12-09 Owen Mumford, Ltd. Injection method and apparatus
US8998855B2 (en) 2008-11-17 2015-04-07 Owen Mumford, Ltd. Syringe and needle cover remover

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BR0114498A (pt) 2004-01-13
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ATE335519T1 (de) 2006-09-15
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