WO1999010385A1 - Gel d'acide hyaluronique, son procede de production et substance therapeutique le contenant - Google Patents
Gel d'acide hyaluronique, son procede de production et substance therapeutique le contenant Download PDFInfo
- Publication number
- WO1999010385A1 WO1999010385A1 PCT/JP1998/003536 JP9803536W WO9910385A1 WO 1999010385 A1 WO1999010385 A1 WO 1999010385A1 JP 9803536 W JP9803536 W JP 9803536W WO 9910385 A1 WO9910385 A1 WO 9910385A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hyaluronic acid
- gel
- aqueous solution
- acid gel
- molecular weight
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ502815A NZ502815A (en) | 1997-08-22 | 1998-08-07 | Hyaluronic acid gel formed from a freeze/thawing process of an acidified hyaluronic acid aqueous solution |
CA002301018A CA2301018C (en) | 1997-08-22 | 1998-08-07 | Hyaluronic acid gel, method of its production and medical material containing it |
US09/463,993 US6387413B1 (en) | 1997-08-22 | 1998-08-07 | Hyaluronic acid gel, a method of its production and medical material containing it |
DK98936706T DK1005874T3 (da) | 1997-08-22 | 1998-08-07 | Hyaluronsyregel, fremgangsmåde til fremstilling af samme og medicinsk materiale indeholdende samme |
DE69830240T DE69830240T2 (de) | 1997-08-22 | 1998-08-07 | Hyaluronsäure-gel, verfahren zur dessen herstellung und hyaluronsäure-gel enthaltendes medizinisches material |
EP98936706A EP1005874B1 (en) | 1997-08-22 | 1998-08-07 | Hyaluronic acid gel, process for producing the same and medical material containing the same |
AU85616/98A AU742675B2 (en) | 1997-08-22 | 1998-08-07 | Hyaluronic acid gel, method of its production and medical material containing it |
JP2000507710A JP3359909B2 (ja) | 1997-08-22 | 1998-08-07 | ヒアルロン酸ゲルとその製造方法及びそれを含有する医用材料 |
AT98936706T ATE295745T1 (de) | 1997-08-22 | 1998-08-07 | Hyaluronsäure-gel, verfahren zur dessen herstellung und hyaluronsäure-gel enthaltendes medizinisches material |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22673497 | 1997-08-22 | ||
JP9/226734 | 1997-08-22 | ||
JP10/117564 | 1998-04-27 | ||
JP11756498 | 1998-04-27 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/463,993 A-371-Of-International US6387413B1 (en) | 1997-08-22 | 1998-08-07 | Hyaluronic acid gel, a method of its production and medical material containing it |
US10/047,091 Continuation US6790461B2 (en) | 1997-08-22 | 2002-01-17 | Hyaluronic acid gel, method of its production and medical material containing it |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999010385A1 true WO1999010385A1 (fr) | 1999-03-04 |
Family
ID=26455658
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1998/003536 WO1999010385A1 (fr) | 1997-08-22 | 1998-08-07 | Gel d'acide hyaluronique, son procede de production et substance therapeutique le contenant |
Country Status (11)
Country | Link |
---|---|
US (2) | US6387413B1 (ja) |
EP (1) | EP1005874B1 (ja) |
JP (1) | JP3359909B2 (ja) |
KR (1) | KR100374666B1 (ja) |
CN (1) | CN1101405C (ja) |
AT (1) | ATE295745T1 (ja) |
AU (1) | AU742675B2 (ja) |
CA (1) | CA2301018C (ja) |
DE (1) | DE69830240T2 (ja) |
NZ (1) | NZ502815A (ja) |
WO (1) | WO1999010385A1 (ja) |
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JP2002348243A (ja) * | 2001-05-28 | 2002-12-04 | Denki Kagaku Kogyo Kk | 関節症治療用注入剤 |
EP1281722A1 (en) * | 2000-02-03 | 2003-02-05 | Denki Kagaku Kogyo Kabushiki Kaisha | Hyaluronic acid gel, process for producing the same, and medical material containing the same |
WO2005000374A1 (ja) * | 2003-06-30 | 2005-01-06 | Denki Kagaku Kogyo Kabushiki Kaisha | 脊椎・脊髄手術用癒着防止材 |
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WO2015002091A1 (ja) * | 2013-07-03 | 2015-01-08 | 株式会社リタファーマ | 水溶性ヒアルロン酸ゲル及びその製造方法 |
WO2015115609A1 (ja) | 2014-01-31 | 2015-08-06 | 生化学工業株式会社 | ジアミン架橋剤、酸性多糖架橋体、及び医用材料 |
US9101697B2 (en) | 2004-04-30 | 2015-08-11 | Abbott Cardiovascular Systems Inc. | Hyaluronic acid based copolymers |
JP2016515821A (ja) * | 2013-03-20 | 2016-06-02 | イルドン ファーム カンパニー リミテッド | ヒアルロン酸の製造方法及び前記製造方法で製造されたヒアルロン酸を含む癒着防止用組成物 |
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CN1101405C (zh) | 1997-08-22 | 2003-02-12 | 电气化学工业株式会社 | 透明质酸凝胶的制备方法、用此方法制得的透明质酸及包含这种凝胶的医用材料 |
-
1998
- 1998-08-07 CN CN98808365A patent/CN1101405C/zh not_active Expired - Lifetime
- 1998-08-07 JP JP2000507710A patent/JP3359909B2/ja not_active Expired - Fee Related
- 1998-08-07 EP EP98936706A patent/EP1005874B1/en not_active Expired - Lifetime
- 1998-08-07 NZ NZ502815A patent/NZ502815A/en not_active IP Right Cessation
- 1998-08-07 AU AU85616/98A patent/AU742675B2/en not_active Ceased
- 1998-08-07 AT AT98936706T patent/ATE295745T1/de active
- 1998-08-07 KR KR10-2000-7001812A patent/KR100374666B1/ko not_active IP Right Cessation
- 1998-08-07 WO PCT/JP1998/003536 patent/WO1999010385A1/ja active IP Right Grant
- 1998-08-07 CA CA002301018A patent/CA2301018C/en not_active Expired - Fee Related
- 1998-08-07 US US09/463,993 patent/US6387413B1/en not_active Expired - Lifetime
- 1998-08-07 DE DE69830240T patent/DE69830240T2/de not_active Expired - Lifetime
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2002
- 2002-01-17 US US10/047,091 patent/US6790461B2/en not_active Expired - Lifetime
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JP4755795B2 (ja) * | 2000-02-03 | 2011-08-24 | 電気化学工業株式会社 | ヒアルロン酸ゲルの製造方法及びそれを含有する医用材料 |
EP1281722A4 (en) * | 2000-02-03 | 2005-06-08 | Denki Kagaku Kogyo Kk | HYALURONIC ACID GEL, METHOD FOR THE PRODUCTION THEREOF, AND THE MEDICAL MATERIAL CONTAINING GEL |
US7014860B1 (en) | 2000-02-03 | 2006-03-21 | Denki Kagaku Kogyo Kabushiki Kaisha | Hyaluronic acid gel, process for producing the same, and medical material containing the same |
JP2001329002A (ja) * | 2000-05-25 | 2001-11-27 | Denki Kagaku Kogyo Kk | 修飾ヒアルロン酸ゲルとその製造方法及びそれを含有する医用材料 |
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US10639266B2 (en) | 2013-07-03 | 2020-05-05 | Ritapharma, Co., Ltd | Water-soluble hyaluronic acid gel and method for producing same |
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US10294195B2 (en) | 2014-01-31 | 2019-05-21 | Seikagaku Corporation | Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials |
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Also Published As
Publication number | Publication date |
---|---|
CN1101405C (zh) | 2003-02-12 |
EP1005874A4 (en) | 2001-02-07 |
EP1005874A1 (en) | 2000-06-07 |
KR100374666B1 (ko) | 2003-03-04 |
DE69830240T2 (de) | 2005-10-13 |
CA2301018C (en) | 2006-06-20 |
CA2301018A1 (en) | 1999-03-04 |
JP3359909B2 (ja) | 2002-12-24 |
US6387413B1 (en) | 2002-05-14 |
US6790461B2 (en) | 2004-09-14 |
ATE295745T1 (de) | 2005-06-15 |
CN1267308A (zh) | 2000-09-20 |
EP1005874B1 (en) | 2005-05-18 |
DE69830240D1 (de) | 2005-06-23 |
AU742675B2 (en) | 2002-01-10 |
US20020098244A1 (en) | 2002-07-25 |
NZ502815A (en) | 2002-03-01 |
KR20010023185A (ko) | 2001-03-26 |
AU8561698A (en) | 1999-03-16 |
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