WO1997025302A1 - 5-benzylhexanol-2 et composition parfumee contenant ce compose - Google Patents
5-benzylhexanol-2 et composition parfumee contenant ce compose Download PDFInfo
- Publication number
- WO1997025302A1 WO1997025302A1 PCT/JP1996/003057 JP9603057W WO9725302A1 WO 1997025302 A1 WO1997025302 A1 WO 1997025302A1 JP 9603057 W JP9603057 W JP 9603057W WO 9725302 A1 WO9725302 A1 WO 9725302A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- benzylhexanol
- fragrance
- acid
- composition containing
- reaction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/0061—Essential oils; Perfumes compounds containing a six-membered aromatic ring not condensed with another ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
- C07C33/20—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2003—Alcohols; Phenols
- C11D3/2006—Monohydric alcohols
- C11D3/2034—Monohydric alcohols aromatic
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/50—Perfumes
Definitions
- the present invention relates to a novel aromatic compound and a fragrance composition containing the same. More specifically, the present invention relates to a novel fragrance compound having a flowery fragrance and applicable to all kinds of fragrance products such as toiletry products, house hold products, personal care products and the like. The present invention relates to 5-benzylhexanol-2 having excellent residual odor in a compounding system and a fragrance composition containing the same. Background art
- aldehyde-based fragrances represented by lilial are the most numerous and one of the important materials.
- aldehyde-based fragrance materials are not always stable in fragrance products with various pH and product forms, it is difficult to provide freshness, natural sensation, softness, volume, and stable residual fragrance. In many cases, there were restrictions on the perfume.
- an object of the present invention is to provide a novel compound having a flowery fragrance, high stability, and excellent residual scent in a compounding system, and a fragrance composition containing the compound. Disclosure of the invention
- the present invention provides the following formula (1) And a fragrance composition containing the same.
- FIG. 1 is a view showing the results of comparing the residual odor of 5-benzylhexanol-2 with lilial and phenethyl alcohol.
- 5-Benzylhexanol-2 has two asymmetric carbon atoms and thus has optical isomers, and any isomers are included in the present invention.
- 5-benzylhexanol-2 of the present invention is a novel compound, it can be synthesized according to a conventionally known method.
- 5-benzylhexanol-2 is obtained by introducing a methylene group by a Mannich reaction using 3-phenylpropionaldehyde as a raw material according to the following reaction formula, hydrogenating it, and then subjecting it to an aldol reaction with acetone and hydrogenating It is manufactured by doing.
- the introduction of a methylene group into 3-phenylpropionaldehyde can be accomplished by adding 3-phenylpropionaldehyde to a 0.8 to 1 mass in the presence of a catalytic amount of a primary or secondary amine and a carboxylic acid having 2 to 20 carbon atoms. It is carried out by reacting with 2 moles of formaldehyde or formalin.
- the primary or secondary amine include butylamine, dimethylamine, getylamine, dibutylamine and the like, and the use amount thereof is preferably 1 to 20% by mole based on 3-phenylpropionaldehyde.
- the carboxylic acids having 2 to 20 carbon atoms include acetic acid, propionic acid, butyric acid, valeric acid, hexanoic acid, heptanoic acid, octanoic acid, decanoic acid, dodecanoic acid, stearic acid, isostearic acid, and cyclohexanecarboxylic acid. Acids, benzoic acid, etc. are preferred, but fatty acids having 6 to 18 carbon atoms are preferred, and the amount of use is preferably 0.1 to 20 mol% with respect to 3-phenylpropionaldehyde.
- a reaction solvent is not always necessary, a polar solvent such as methanol, ethanol, propanol, tetrahydrofuran, dioxane or the like can be used.
- the reaction temperature is preferably 50 to 100 ° C.
- the obtained 2-benzylacrylaldehyde is subjected to catalytic hydrogenation in the presence of a catalyst such as palladium, in a solvent inert to the reaction such as methanol, ethanol, propanol, etc., under a hydrogen atmosphere or under hydrogen pressure. It can lead to 1-methyldihydrocinnamic aldehyde.
- the catalyst to be used is preferably one supported on a carrier such as activated carbon, zeolite, silica or alumina.
- the amount of the catalyst is 0.1 to 50% by weight based on the total amount of the carrier and 2-benzyl acrylaldehyde. Especially 0.5 to 20% by weight preferable.
- the reaction temperature is preferably from 10 to 100 ° C.
- the aldol reaction between trimethyldihydrocinnamic aldehyde and acetone is carried out in the presence of a base.
- a base include sodium hydroxide, potassium hydroxide, potassium carbonate, sodium alkoxide, potassium alkoxide, alkyllithium and the like, in an amount of 0.1 to 0.7 mol based on 1-methylhydrocinnamic aldehyde. It is preferable to use twice.
- a reaction solvent is not always necessary, but methanol, ethanol, tetrahydrofuran, getyl ether, and the like can also be used.
- the reaction temperature is preferably -80 to 60 ° C.
- the obtained 5-benzyl-3-hexen-2-one can be obtained in a solvent inert to a reaction such as methanol, ethanol, or propanol, in the presence of a catalyst such as Raney nickel or rhodium, in a hydrogen atmosphere or under hydrogen pressure.
- a catalyst such as Raney nickel or rhodium
- the amount of the catalyst used is preferably 0.1 to 50% by weight, and particularly preferably 0.5 to 20% by weight, based on 5-benzyl-3-hexen-2-one.
- the reaction temperature is preferably from 10 to 100 ° C.
- the desired 5-benzylhexanol-2 can be obtained by appropriately purifying by means such as decantation and column chromatography.
- the thus obtained 5-benzylhexanol-2 has a flowery fragrance itself and can be used as a fragrance component alone or in combination with other components.
- the amount of 5-benzylhexanol-2 to be added to the fragrance composition depends on the type of the compounded fragrance to be used together, the type and intensity of the desired fragrance, etc. Although it is not particularly limited, it is generally preferable to add 0.1 to 90% by weight, particularly preferably 0.5 to 70% by weight.
- the perfume composition of the present invention is widely used for perfumes, soaps, shampoos, rinses, detergents, cosmetics, sprays, fragrances, and other toilet products, household products, personal care products, and other products that require incense. be able to.
- a 1-liter 4-neck flask equipped with a thermometer and a condenser was charged with 7.8 g (0.2 mol) of sodium hydroxide, 25 m of water and 360 ⁇ ⁇ of acetone, and stirred at 30 ° C under a nitrogen atmosphere with stirring.
- a solution of 97 g (0.65mo ⁇ ) of methyldihydrocinnamic aldehyde in 100 ⁇ ⁇ of acetone was added dropwise over 20 minutes. After completion of the dropwise addition, the mixture was stirred at room temperature for 1 hour, and the reaction was stopped with 12 m (0.2 mol) of drunk acid, and excess acetone was distilled off.
- the obtained aroma of 5-benzylhexanol-2 had a floral feeling with lactone-like sweetness, and also had excellent residual odor.
- the test was performed by sensory evaluation of three specialized panelists. Each sample was attached to the tip of odor paper of 5 countries in width of 50 si £ each, left in a room, and the residual odor was evaluated with time. In the evaluation, the intensity of the fragrance immediately after the application of Lilyal to the odor paper was set to 5, and the average was shown by three persons. The aroma intensity immediately after the other samples was 4.5 for phenethyl alcohol and 4.3 for 5-benzylhexanol-2. The result is shown in FIG.
- 5-Benzylhexanol-2 has a flowery aroma, and has a fresh, natural, soft, voluminous and stable lingering scent in the formulation of the product.
- Perfume, soap, shampoo It can be widely used for products requiring fragrance, such as, rinsing, detergent, cosmetics, spray, and fragrance.
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
- Fats And Perfumes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/091,819 US6262014B1 (en) | 1996-01-10 | 1996-10-22 | 5-Benzylhexanol-2 and perfume composition containing it |
EP96935394A EP0882694B1 (en) | 1996-01-10 | 1996-10-22 | 5-benzylhexanol-2 and perfume composition containing it |
DE69614572T DE69614572T2 (de) | 1996-01-10 | 1996-10-22 | 5-benzylhexanol-2 und parfümzusammensetzung die dieses enthält |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP00214896A JP3642860B2 (ja) | 1996-01-10 | 1996-01-10 | 5−ベンジルヘキサノール−2及びこれを含有する香料組成物 |
JP8/2148 | 1996-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997025302A1 true WO1997025302A1 (fr) | 1997-07-17 |
Family
ID=11521279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1996/003057 WO1997025302A1 (fr) | 1996-01-10 | 1996-10-22 | 5-benzylhexanol-2 et composition parfumee contenant ce compose |
Country Status (5)
Country | Link |
---|---|
US (1) | US6262014B1 (ja) |
EP (1) | EP0882694B1 (ja) |
JP (1) | JP3642860B2 (ja) |
DE (1) | DE69614572T2 (ja) |
WO (1) | WO1997025302A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112016010349B1 (pt) * | 2013-11-08 | 2022-03-08 | Firmenich Sa | Uso como ingrediente de perfumadura, composição de perfumadura e produto de perfumadura |
US10232165B2 (en) | 2015-01-29 | 2019-03-19 | Elwha Llc | Garment system including at least one sensor and at least one actuator responsive to the sensor and related methods |
US11638676B2 (en) | 2014-08-26 | 2023-05-02 | Ventrk, Llc | Garment system including at least one sensor and at least one actuator responsive to the sensor and related methods |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5551014A (en) * | 1978-10-06 | 1980-04-14 | Int Flavors & Fragrances Inc | Novel aromatic composition containing 33methyll11phenyllpentanoll5 or its specific optical isomer and more than one butanoylcyclohexane derivatives |
JPS63258824A (ja) * | 1987-04-15 | 1988-10-26 | コンソルテイウム・フュア・エレクトロケミッシェ・インドゥストリー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 2―メチル基または2―メトキシフエニル基含有アルコールおよび該アルコールを含む香料 |
JPS6456635A (en) * | 1987-08-25 | 1989-03-03 | Kao Corp | 2,2,4-trimethyl-1-phenyl-3-pentanol and perfume composition containing said compound |
JPH01503536A (ja) * | 1987-02-06 | 1989-11-30 | コンゾルテイウム フユール エレクトロケミツシエ インヅストリー ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 3―メチル―又は3,5―ジメチルフェニル基を有するアルコール、その製法及びこれよりなる香料 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3439203A1 (de) * | 1984-10-26 | 1986-04-30 | Basf Ag, 6700 Ludwigshafen | 1-phenyl-2-methyl-3-hydroxy-(3-alkoxy)-alkylverbindungen, deren herstellung und verwendung als riechstoffe |
US4610812A (en) * | 1984-12-14 | 1986-09-09 | International Flavors & Fragrances Inc. | Uses of methyl phenyl pentanol derivatives in augmenting or enhancing the aroma or taste of consumable materials |
US5552380A (en) * | 1994-12-15 | 1996-09-03 | International Flavors & Fragrances Inc. | Perfume uses of phenyl alkanol derivatives |
-
1996
- 1996-01-10 JP JP00214896A patent/JP3642860B2/ja not_active Expired - Fee Related
- 1996-10-22 DE DE69614572T patent/DE69614572T2/de not_active Expired - Lifetime
- 1996-10-22 US US09/091,819 patent/US6262014B1/en not_active Expired - Lifetime
- 1996-10-22 WO PCT/JP1996/003057 patent/WO1997025302A1/ja active IP Right Grant
- 1996-10-22 EP EP96935394A patent/EP0882694B1/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5551014A (en) * | 1978-10-06 | 1980-04-14 | Int Flavors & Fragrances Inc | Novel aromatic composition containing 33methyll11phenyllpentanoll5 or its specific optical isomer and more than one butanoylcyclohexane derivatives |
JPH01503536A (ja) * | 1987-02-06 | 1989-11-30 | コンゾルテイウム フユール エレクトロケミツシエ インヅストリー ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 3―メチル―又は3,5―ジメチルフェニル基を有するアルコール、その製法及びこれよりなる香料 |
JPS63258824A (ja) * | 1987-04-15 | 1988-10-26 | コンソルテイウム・フュア・エレクトロケミッシェ・インドゥストリー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 2―メチル基または2―メトキシフエニル基含有アルコールおよび該アルコールを含む香料 |
JPS6456635A (en) * | 1987-08-25 | 1989-03-03 | Kao Corp | 2,2,4-trimethyl-1-phenyl-3-pentanol and perfume composition containing said compound |
Non-Patent Citations (1)
Title |
---|
See also references of EP0882694A4 * |
Also Published As
Publication number | Publication date |
---|---|
DE69614572T2 (de) | 2001-11-22 |
EP0882694A4 (en) | 1999-03-31 |
US6262014B1 (en) | 2001-07-17 |
EP0882694B1 (en) | 2001-08-16 |
EP0882694A1 (en) | 1998-12-09 |
JPH09188641A (ja) | 1997-07-22 |
JP3642860B2 (ja) | 2005-04-27 |
DE69614572D1 (de) | 2001-09-20 |
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