UY35002A - Nanopartícula polimérica de finasterida y minoxidil, proceso de preparación, suspensión acuosa conteniendo la misma, composición farmacéutica, y su uso - Google Patents

Nanopartícula polimérica de finasterida y minoxidil, proceso de preparación, suspensión acuosa conteniendo la misma, composición farmacéutica, y su uso

Info

Publication number
UY35002A
UY35002A UY0001035002A UY35002A UY35002A UY 35002 A UY35002 A UY 35002A UY 0001035002 A UY0001035002 A UY 0001035002A UY 35002 A UY35002 A UY 35002A UY 35002 A UY35002 A UY 35002A
Authority
UY
Uruguay
Prior art keywords
minoxidil
pharmaceutical composition
financial
preparation process
same
Prior art date
Application number
UY0001035002A
Other languages
English (en)
Inventor
Adriana Raffin Pohlmann
Denise Soledade Jornada;
Ludmila Pinheiro Do Nascimento
Silvia Stanisçuaski Guterres
Original Assignee
Biolab Sanus Farmac Utica Ltda
Univ Fed Do Rio Grande Do Sul
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50182296&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY35002(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biolab Sanus Farmac Utica Ltda, Univ Fed Do Rio Grande Do Sul filed Critical Biolab Sanus Farmac Utica Ltda
Publication of UY35002A publication Critical patent/UY35002A/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica, de vehiculación tópica, para el tratamiento de la alopecia, dicha composición comprende nanopartículas poliméricas, preferentemente nanocapsoides, conteniendo dos principios activos, finasterida y minoxidil, aditivos y vehículo farmacéuticamente aceptables. La invención además incluye un proceso de preparación de las nanopartículas polimércias, preferentemente nanocapsoides de finasterida y minoxidil, apropiadas para una composición de vehiculación tópica para el tratamiento de la alopecia, así como el uso de dichos nanocapsoides para la preparación de una composición farmacéut ica.
UY0001035002A 2012-08-31 2013-08-30 Nanopartícula polimérica de finasterida y minoxidil, proceso de preparación, suspensión acuosa conteniendo la misma, composición farmacéutica, y su uso UY35002A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR102012022036-9A BR102012022036B1 (pt) 2012-08-31 2012-08-31 Nanopartícula polimérica de finasterida e minoxidil, processo de sua preparação, suspensão aquosa contendo a mesma, composição farmacêutica, e seu uso

Publications (1)

Publication Number Publication Date
UY35002A true UY35002A (es) 2014-03-31

Family

ID=50182296

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035002A UY35002A (es) 2012-08-31 2013-08-30 Nanopartícula polimérica de finasterida y minoxidil, proceso de preparación, suspensión acuosa conteniendo la misma, composición farmacéutica, y su uso

Country Status (23)

Country Link
US (1) US9687554B2 (es)
EP (1) EP2891486B1 (es)
JP (1) JP6352265B2 (es)
KR (1) KR102118582B1 (es)
CN (1) CN104755075B (es)
AR (1) AR092403A1 (es)
AU (1) AU2013308356B2 (es)
BR (1) BR102012022036B1 (es)
CA (1) CA2883998C (es)
CL (1) CL2015000501A1 (es)
CO (1) CO7310520A2 (es)
DK (1) DK2891486T3 (es)
ES (1) ES2683418T3 (es)
IN (1) IN2015DN01728A (es)
MX (1) MX363961B (es)
MY (1) MY174692A (es)
PE (2) PE20150732A1 (es)
SA (1) SA515360084B1 (es)
TR (1) TR201810389T4 (es)
UA (1) UA113774C2 (es)
UY (1) UY35002A (es)
WO (1) WO2014032152A1 (es)
ZA (1) ZA201501255B (es)

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ES2613888B1 (es) * 2016-08-19 2017-11-16 Enrique Blanxart Sena Composición farmacéutica para el tratamiento de la alopecia
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WO2020097284A1 (en) * 2018-11-08 2020-05-14 Jindal Vinay K TOPICAL FORMULATIONS OF 5-α-REDUCTASE INHIBITORS AND USES THEREOF
WO2020121329A1 (en) * 2018-12-11 2020-06-18 Dr Rathod Sudha Suresh Minoxidil and castor oil nanoemulgel for alopecia
CN112773776B (zh) * 2019-11-11 2023-06-20 上海胜联医药科技有限公司 一种载药纳米粒体系
CN111329832B (zh) * 2020-02-08 2021-07-16 中山大学 一种治疗脱发的纳米脂质载体微针及其应用
EP4114362A4 (en) * 2020-03-05 2024-03-20 Univ Miami NANODRUG FORMULATIONS OF CANNABIDIOL AND THEIR METHODS OF USE
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CN113797208B (zh) * 2021-11-17 2022-02-25 山东谷雨春生物科技有限公司 一种含米诺地尔的制剂及其制备方法和应用
KR20230113871A (ko) 2022-01-24 2023-08-01 (주) 해피론이엔지 발포폴리에틸렌메시를 이용한 건축물 층간소음방지 시공방법 및 구조.
KR102623083B1 (ko) 2022-05-02 2024-01-10 (주) 해피론이엔지 공명공간을 제거한 1차 몰탈 타설식 소음방지 시공공법 및 시공구조
CN115006712B (zh) * 2022-06-28 2024-01-09 广州汇元医药科技有限公司 一种米诺地尔的脂质纳米粒微针及其制备方法和应用
CN115252549B (zh) * 2022-07-12 2023-09-08 科辉智药生物科技（无锡）有限公司 提高生发活性物质药效的组合物及其制备方法
CN115400085A (zh) * 2022-09-02 2022-11-29 南昌大学 一种非那雄胺类脂囊泡及其制备方法和应用

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Also Published As

Publication number Publication date
MX363961B (es) 2019-04-09
CA2883998C (en) 2020-08-25
CN104755075A (zh) 2015-07-01
MY174692A (en) 2020-05-07
KR20150044029A (ko) 2015-04-23
EP2891486A1 (en) 2015-07-08
BR102012022036A2 (pt) 2014-11-25
ES2683418T3 (es) 2018-09-26
AR092403A1 (es) 2015-04-22
CN104755075B (zh) 2019-07-26
IN2015DN01728A (es) 2015-05-29
PE20150732A1 (es) 2015-05-17
US9687554B2 (en) 2017-06-27
JP2015526484A (ja) 2015-09-10
CO7310520A2 (es) 2015-06-30
US20150216986A1 (en) 2015-08-06
KR102118582B1 (ko) 2020-06-04
AU2013308356A1 (en) 2015-04-16
JP6352265B2 (ja) 2018-07-04
MX2015002300A (es) 2016-02-10
EP2891486B1 (en) 2018-05-16
EP2891486A4 (en) 2016-03-23
UA113774C2 (xx) 2017-03-10
CL2015000501A1 (es) 2015-07-03
WO2014032152A1 (pt) 2014-03-06
PE20191714A1 (es) 2019-12-05
CA2883998A1 (en) 2014-03-06
DK2891486T3 (en) 2018-07-23
BR102012022036B1 (pt) 2019-10-01
ZA201501255B (en) 2016-01-27
TR201810389T4 (tr) 2018-08-27
AU2013308356B2 (en) 2017-09-28
SA515360084B1 (ar) 2016-10-03

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