UY34145A - Compuestos inhibidores de metaloenzimas - Google Patents

Compuestos inhibidores de metaloenzimas

Info

Publication number
UY34145A
UY34145A UY0001034145A UY34145A UY34145A UY 34145 A UY34145 A UY 34145A UY 0001034145 A UY0001034145 A UY 0001034145A UY 34145 A UY34145 A UY 34145A UY 34145 A UY34145 A UY 34145A
Authority
UY
Uruguay
Prior art keywords
metaloenzym
inhibiting compounds
inhibiting
compounds
pag
Prior art date
Application number
UY0001034145A
Other languages
English (en)
Spanish (es)
Inventor
Hoekstra William
Yates Christopher
Robert J Schotzinger
Michael R Loso
Zachary A Buchan
Michael T Sullenberger
Original Assignee
Viamet Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viamet Pharmaceuticals Inc filed Critical Viamet Pharmaceuticals Inc
Priority to UY0001039413A priority Critical patent/UY39413A/es
Publication of UY34145A publication Critical patent/UY34145A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
UY0001034145A 2011-06-19 2012-06-20 Compuestos inhibidores de metaloenzimas UY34145A (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY0001039413A UY39413A (es) 2011-06-19 2012-06-20 Compuestos inhibidores de metaloenzimas

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161498570P 2011-06-19 2011-06-19
US201261611897P 2012-03-16 2012-03-16

Publications (1)

Publication Number Publication Date
UY34145A true UY34145A (es) 2013-01-31

Family

ID=47362418

Family Applications (2)

Application Number Title Priority Date Filing Date
UY0001034145A UY34145A (es) 2011-06-19 2012-06-20 Compuestos inhibidores de metaloenzimas
UY0001039413A UY39413A (es) 2011-06-19 2012-06-20 Compuestos inhibidores de metaloenzimas

Family Applications After (1)

Application Number Title Priority Date Filing Date
UY0001039413A UY39413A (es) 2011-06-19 2012-06-20 Compuestos inhibidores de metaloenzimas

Country Status (23)

Country Link
US (3) US8748461B2 (enExample)
EP (4) EP2721022B1 (enExample)
JP (3) JP6247632B2 (enExample)
KR (4) KR20180095108A (enExample)
CN (3) CN103781775B (enExample)
AR (1) AR088130A1 (enExample)
AU (2) AU2012273103B2 (enExample)
BR (2) BR102012015179B1 (enExample)
CA (2) CA2838912C (enExample)
CL (1) CL2013003638A1 (enExample)
CO (1) CO6930356A2 (enExample)
CR (1) CR20140020A (enExample)
EA (2) EA024789B1 (enExample)
EC (2) ECSP14013152A (enExample)
ES (1) ES2700250T3 (enExample)
IL (1) IL229965A (enExample)
IN (1) IN2014DN00288A (enExample)
MX (1) MX351943B (enExample)
PH (1) PH12013502623A1 (enExample)
UA (1) UA114090C2 (enExample)
UY (2) UY34145A (enExample)
WO (2) WO2012177635A1 (enExample)
ZA (1) ZA201400232B (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012177603A2 (en) * 2011-06-19 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
CN103781775B (zh) * 2011-06-19 2016-11-16 威尔金制药有限公司 金属酶抑制剂化合物
AU2012273004B2 (en) 2011-06-23 2017-04-13 Mycovia Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
IN2014DN06792A (enExample) 2012-01-20 2015-05-22 Viamet Pharmaceuticals Inc
AU2014209107B2 (en) * 2013-01-28 2018-04-12 Viamet Pharmaceuticals (NC), Inc. Metalloenzyme inhibitor compounds
BR112015025679A8 (pt) 2013-04-12 2020-02-11 Bayer Cropscience Ag novos derivados de triazol
WO2014167008A1 (en) 2013-04-12 2014-10-16 Bayer Cropscience Ag Novel triazolinthione derivatives
CN105308032B (zh) 2013-04-12 2017-05-24 拜耳作物科学股份公司 新的三唑衍生物
EP3004067A4 (en) * 2013-05-28 2016-10-12 Viamet Pharmaceuticals Inc FUNGICIDE COMPOSITIONS
AU2014278172B2 (en) 2013-06-12 2018-08-09 Mycovia Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
WO2015027863A1 (zh) * 2013-08-27 2015-03-05 中国中化股份有限公司 含取代苄氧基的醚类化合物作为制备抗肿瘤药物的应用
CA2942927A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
WO2015143166A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
WO2015143162A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
MX2016012060A (es) * 2014-03-19 2017-01-19 Viamet Pharmaceuticals Inc 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procesos para su preparacion.
EP3119754A4 (en) * 2014-03-19 2017-12-13 Viamet Pharmaceuticals, Inc. Antifungal compound process
BR112016021257B1 (pt) * 2014-03-19 2021-03-02 Viamet Pharmaceuticals (NC), Inc. 2-(2,4- difluorofenil-1,1-diflúor-1-(5-substituído-piridin-2-il)-3- (1h-tetrazol-1-il)propan-2-óis e processos para preparação e uso dos mesmos
EP3119745B1 (en) 2014-03-19 2020-08-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
WO2015143154A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
JP2017509646A (ja) 2014-03-19 2017-04-06 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 抗真菌化合物の調製方法
US10017494B2 (en) 2014-03-19 2018-07-10 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP6623015B2 (ja) * 2014-09-29 2019-12-18 国立研究開発法人理化学研究所 植物の耐塩性向上剤
CN107001338A (zh) 2014-10-02 2017-08-01 拜耳作物科学股份公司 新的用作杀真菌剂的三唑衍生物
WO2016156294A1 (en) 2015-04-02 2016-10-06 Bayer Cropscience Aktiengesellschaft Triazol derivatives as fungicides
WO2016187201A2 (en) * 2015-05-18 2016-11-24 Viamet Pharmaceuticals, Inc. Antifungal compounds
WO2017049096A1 (en) * 2015-09-18 2017-03-23 Viamet Pharmaceuticals, Inc. Antifungal compound process
ES2909122T3 (es) 2015-11-09 2022-05-05 Forge Therapeutics Inc Compuestos a base de hidroxipiridinona e hidroxipirimidinona para el tratamiento de infecciones bacterianas
WO2017083434A1 (en) 2015-11-09 2017-05-18 Forge Therapeutics, Inc. Pyrone based compounds for treating bacterial infections
EP3377475A4 (en) * 2015-11-17 2019-04-10 Dow Agrosciences Llc 4 - ((6-2- (2,4-difluorophenyl) -1,1-difluoro-2-hydroxy-3- (1H-1,2,4-triazol-1-YL) PROPYL) PYRIDINE-3-YL ) OXY) BENZONITRIL AND METHOD OF PREPARING THEREOF
KR20180100313A (ko) * 2015-11-17 2018-09-10 다우 아그로사이언시즈 엘엘씨 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-히드록시-3-(1h-1,2,4-트리아졸-1-일)프로필)피리딘-3-일)옥시)벤조니트릴 및 제조방법
BR112018009920A2 (pt) * 2015-11-17 2018-11-13 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorfenil)-1,1-diflúor-2-hidróxi-3-(1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação
KR20180101343A (ko) * 2015-11-17 2018-09-12 다우 아그로사이언시즈 엘엘씨 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-옥소에틸)피리딘-3-일)옥시)벤조니트릴 및 제조방법
CN113912586B (zh) 2016-08-31 2023-04-07 江苏恒瑞医药股份有限公司 氧代吡啶酰胺类衍生物、其制备方法及其在医药上的应用
JP2018048090A (ja) * 2016-09-21 2018-03-29 大阪ガスケミカル株式会社 工業用保存剤
CN109983005A (zh) * 2016-11-18 2019-07-05 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
US20190330184A1 (en) * 2016-11-18 2019-10-31 Dow Agrosciences Llc 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
BR112019009801A2 (pt) * 2016-11-18 2019-08-06 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação
BR112019009759A2 (pt) * 2016-11-18 2019-08-13 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação
US20190284159A1 (en) * 2016-11-18 2019-09-19 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
US20190284161A1 (en) * 2016-11-18 2019-09-19 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
BR112019009812A2 (pt) * 2016-11-18 2019-08-13 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação
BR112019009787A2 (pt) * 2016-11-18 2019-08-06 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro -2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil) piridina-3-il)óxi)benzonitrila e processos de preparação
EP3544434A4 (en) * 2016-11-22 2020-04-15 Dow AgroSciences LLC USE OF A DIFLUORO- (2-HYDROXYPROPYL) PYRIDINE COMPOUND AS A FUNGICIDE FOR THE CONTROL OF PHYTOPATHOGENIC BARLEY FUNGI
CA3044340A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Fungicidal compounds and mixtures for fungal control in cereals
WO2018098256A1 (en) * 2016-11-22 2018-05-31 Vps-3, Inc. Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of rice
RU2749224C2 (ru) * 2016-11-22 2021-06-07 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Фунгицидные соединения и смеси для борьбы с грибковыми заболеваниями зерновых культур
AR110214A1 (es) * 2016-11-22 2019-03-06 Viamet Pharmaceuticals Inc Compuestos y mezclas fungicidas para el control de hongos en cereales
EP3544429A4 (en) * 2016-11-22 2020-04-29 Dow Agrosciences Llc USE OF A DIFLUORO- (2-HYDROXYPROPYL) PYRIDINE COMPOUND AS A FUNGICIDE FOR THE CONTROL OF WHEAT PHYTOPATHOGENIC FUNGI
AR110209A1 (es) * 2016-11-22 2019-03-06 Viamet Pharmaceuticals Inc Uso de un compuesto de difluoro-(2-hidroxipropil)piridina como fungicida para el control de hongos fitopatógenos en maíz
BR112019010142A2 (pt) * 2016-11-22 2019-09-17 Dow Agrosciences Llc compostos de fungicida e misturas para controle fúngico em cereais
MA46135B2 (fr) 2016-11-22 2021-01-29 Dow Agrosciences Llc Composés et mélanges fongicides pour la lutte contre les maladies fongiques dans des céréales
JP2019535752A (ja) * 2016-11-22 2019-12-12 ダウ アグロサイエンシィズ エルエルシー テンサイの斑点病の防除のための殺真菌剤としてのジフルオロ−（２−ヒドロキシプロピル）ピリジン化合物の使用
MX378460B (es) 2016-12-22 2025-03-10 Calithera Biosciences Inc Composiciones y métodos para inhibir la actividad de la arginasa.
EP3621962A4 (en) 2017-05-10 2020-12-09 Forge Therapeutics, Inc. ANTIBACTERIAL COMPOUNDS
EP3710432A1 (en) 2017-11-13 2020-09-23 Bayer Aktiengesellschaft Tetrazolylpropyl derivatives and their use as fungicides
KR20210070308A (ko) 2018-09-20 2021-06-14 포지 테라퓨틱스, 인크. 항균 화합물
WO2021195260A1 (en) 2020-03-25 2021-09-30 Forge Therapeutics, Inc. Lpxc inhibitor and methods of making
TW202144340A (zh) 2020-04-03 2021-12-01 大陸商江蘇恆瑞醫藥股份有限公司 稠合咪唑類衍生物、其製備方法及其在醫藥上的應用
CN113278409B (zh) * 2021-06-22 2022-04-29 西南石油大学 一种高温酸化缓蚀剂
WO2023055686A1 (en) 2021-09-28 2023-04-06 Blacksmith Medicines, Inc. Lpxc inhibitors and uses thereof
CN117069693A (zh) * 2022-05-16 2023-11-17 上海济煜医药科技有限公司 一类含胺基结构化合物的制备方法及作为抗菌剂的应用
WO2024068655A1 (en) 2022-09-28 2024-04-04 Syngenta Crop Protection Ag Fungicidal compositions
WO2024068656A1 (en) 2022-09-28 2024-04-04 Syngenta Crop Protection Ag Fungicidal compositions

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8304282D0 (en) * 1983-02-16 1983-03-23 Pfizer Ltd Antifungal agents
US5087240A (en) 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US4921475A (en) 1983-08-18 1990-05-01 Drug Delivery Systems Inc. Transdermal drug patch with microtubes
DE3470881D1 (de) * 1983-12-20 1988-06-09 Ciba Geigy Ag Microbizides
US4738851A (en) 1985-09-27 1988-04-19 University Of Iowa Research Foundation, Inc. Controlled release ophthalmic gel formulation
US5163899A (en) 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
GB8804164D0 (en) 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US4882150A (en) 1988-06-03 1989-11-21 Kaufman Herbert E Drug delivery system
GB8819308D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
US5008110A (en) 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5088977A (en) 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
US5521222A (en) 1989-09-28 1996-05-28 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
CA2031376A1 (en) 1989-12-04 1991-06-05 Bahram Farhadieh Single layer transdermal drug administration system
US5077033A (en) 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
JP2594486B2 (ja) 1991-01-15 1997-03-26 アルコン ラボラトリーズ インコーポレイテッド 局所的眼薬組成物
GB9121456D0 (en) * 1991-10-10 1991-11-27 Pfizer Ltd Triazole antifungal agents
US5352456A (en) 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
JPH07502219A (ja) 1991-12-18 1995-03-09 ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー 多重層型バリアー構造体
EP0553769B1 (de) 1992-01-29 1996-01-03 FRANZ VÖLKL GmbH & CO. SKI UND TENNIS SPORTARTIKELFABRIK KG Ballspielschläger, insbesondere Tennisschläger
IL114193A (en) 1994-06-20 2000-02-29 Teva Pharma Ophthalmic pharmaceutical compositions based on sodium alginate
ES2094688B1 (es) 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
IT1283911B1 (it) 1996-02-05 1998-05-07 Farmigea Spa Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo
US5800807A (en) 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
US6197934B1 (en) 1998-05-22 2001-03-06 Collagenesis, Inc. Compound delivery using rapidly dissolving collagen film
AU2007323614B2 (en) * 2006-11-21 2012-09-20 Viamet Pharmaceuticals, Inc. Metallo-oxidoreductase inhibitors using metal binding moieties in combination with targeting moieties
WO2008124131A1 (en) * 2007-04-05 2008-10-16 The John Hopkins University Antifungal agents as neuroprotectants
HRP20160172T1 (hr) * 2010-04-24 2016-05-06 Viamet Pharmaceuticals, Inc. Spojevi koji su inhibitori metaloenzima
WO2012177603A2 (en) * 2011-06-19 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
CN103781775B (zh) * 2011-06-19 2016-11-16 威尔金制药有限公司 金属酶抑制剂化合物

Also Published As

Publication number Publication date
EA201490030A1 (ru) 2014-05-30
UY39413A (es) 2021-10-29
US8748461B2 (en) 2014-06-10
CA2838912A1 (en) 2012-12-27
US20120329788A1 (en) 2012-12-27
EP2721023A4 (en) 2014-11-26
MX351943B (es) 2017-11-03
UA114090C2 (uk) 2017-04-25
KR101912848B1 (ko) 2018-10-30
CN103781775B (zh) 2016-11-16
CN105884743A (zh) 2016-08-24
CA2838912C (en) 2019-11-26
CN103764647A (zh) 2014-04-30
EP3067350A1 (en) 2016-09-14
ZA201400232B (en) 2015-06-24
CO6930356A2 (es) 2014-04-28
JP2014518220A (ja) 2014-07-28
KR20140040237A (ko) 2014-04-02
IL229965A (en) 2016-06-30
JP2014517068A (ja) 2014-07-17
EP2721022A4 (en) 2014-11-26
US20130005752A1 (en) 2013-01-03
AR088130A1 (es) 2014-05-14
AU2012273100A1 (en) 2014-01-16
EP2721023A1 (en) 2014-04-23
ECSP22051489A (es) 2022-07-29
ES2700250T3 (es) 2019-02-14
CA2839691A1 (en) 2012-12-27
MX2013015158A (es) 2014-12-05
KR20180095108A (ko) 2018-08-24
US8796001B2 (en) 2014-08-05
JP2017132766A (ja) 2017-08-03
AU2012273103B2 (en) 2017-04-20
EA025406B1 (ru) 2016-12-30
KR20140040236A (ko) 2014-04-02
EA024789B1 (ru) 2016-10-31
CR20140020A (es) 2014-07-02
JP6247632B2 (ja) 2017-12-13
JP6158797B2 (ja) 2017-07-05
CL2013003638A1 (es) 2014-10-10
AU2012273103A1 (en) 2014-01-23
EP2721023B1 (en) 2018-08-08
AU2012273100B2 (en) 2017-05-25
CN103781775A (zh) 2014-05-07
WO2012177635A1 (en) 2012-12-27
KR101912844B1 (ko) 2018-10-30
WO2012177638A1 (en) 2012-12-27
US9220265B2 (en) 2015-12-29
HK1198163A1 (en) 2015-03-13
CN103764647B (zh) 2016-05-18
IN2014DN00288A (enExample) 2015-06-05
BR102012015179B1 (pt) 2021-09-14
BR122020013521B1 (pt) 2021-05-25
PH12013502623A1 (en) 2014-02-10
EP2721022B1 (en) 2019-03-06
KR20180095109A (ko) 2018-08-24
EP2721022A1 (en) 2014-04-23
BR102012015179A2 (pt) 2014-04-22
EA201490029A1 (ru) 2014-11-28
US20140288107A1 (en) 2014-09-25
EP3398944A1 (en) 2018-11-07
CN105884743B (zh) 2019-08-06
ECSP14013152A (es) 2014-04-30
EP3067350B1 (en) 2018-06-13

Similar Documents

Publication Publication Date Title
UY34145A (es) Compuestos inhibidores de metaloenzimas
UY34146A (es) Compuestos inhibidores de metaloenzimas
UY34591A (es) Compuestos de imidazopirrolidinona
UY34550A (es) Bencilpirazoles sustituidos
UY34156A (es) Compuestos inhibidores de metaloenzimas
UY34523A (es) Derivados de betulina
UY34472A (es) Derivados modificados de 4-fenil-piridina
UY33925A (es) Inhibidores tricíclicos de quinasas
UY34445A (es) Nuevos compuestos inhibidores de la fosfodiesterasa del tipo 10a
UY34051A (es) Derivados de pirrolotriazinona como inhibidores de pi3k
UY34045A (es) Derivados de imidazopiridina como inhibidores de pi3k
UY34374A (es) Benzilindazoles sustituidos
UY34654A (es) Inhibidores de la beta-secretasa
UY34820A (es) Compuestos tipo pirrolo-pirrolidinona
UY34138A (es) Antagonistas de trpv4
UY33958A (es) Inhibidores de la glucosilceramida sintasa
UY34763A (es) Inhibidores de la agregación plaquetaria
CR20140468A (es) Inhibidores de diacilglicerol aciltransferasa 2
UY34817A (es) Tienopirimidinas
UY34027A (es) Inhibidores sustituidos de acetil-coa carboxilasa.
UY34503A (es) ?sal de bromhidrato de pridopidina?
UY34092A (es) Nuevos compuestos como inhibidores de jak
UY34365A (es) Compuestos heterociclicos
UY34765A (es) Compuestos novedosos.
UY4175Q (es) Reloj pulsera