UY26485A1 - "pirroles sustituidos" - Google Patents

"pirroles sustituidos"

Info

Publication number
UY26485A1
UY26485A1 UY26485A UY26485A UY26485A1 UY 26485 A1 UY26485 A1 UY 26485A1 UY 26485 A UY26485 A UY 26485A UY 26485 A UY26485 A UY 26485A UY 26485 A1 UY26485 A1 UY 26485A1
Authority
UY
Uruguay
Prior art keywords
substituted pyrroles
treatment
disclosed
control
cancer
Prior art date
Application number
UY26485A
Other languages
English (en)
Inventor
Allen John Lovey
Emily Aijun Liu
Giussepe Federico Weber
John Guilfoyle Mullin Jr
Nader Fotouhi
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of UY26485A1 publication Critical patent/UY26485A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se revelan nuevos pirroles sustituidos de fórmula. Tales compuestos y sus sales farmacéuticamente aceptables son adecuados para la administración a pacientes como solución de infusión continua y son útiles para el tratamiento y/o control de trastornos de proliferación celular, en particular el cáncer. Se revelan asimismo composiciones farmacéuticas que contienen los compuestos mencionados, y métodos para el tratamiento y/o control del cáncer.
UY26485A 1999-12-16 2000-12-15 "pirroles sustituidos" UY26485A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17105199P 1999-12-16 1999-12-16

Publications (1)

Publication Number Publication Date
UY26485A1 true UY26485A1 (es) 2001-06-29

Family

ID=22622296

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26485A UY26485A1 (es) 1999-12-16 2000-12-15 "pirroles sustituidos"

Country Status (33)

Country Link
US (1) US6313143B1 (es)
EP (1) EP1242408B1 (es)
JP (2) JP2003516986A (es)
KR (1) KR100507422B1 (es)
CN (1) CN1229374C (es)
AR (1) AR029415A1 (es)
AT (1) ATE306484T1 (es)
AU (1) AU783616B2 (es)
BR (1) BRPI0016329B8 (es)
CA (1) CA2392902C (es)
CO (1) CO5050293A1 (es)
CZ (1) CZ304130B6 (es)
DE (1) DE60023182T2 (es)
ES (1) ES2249314T3 (es)
GC (1) GC0000265A (es)
HK (1) HK1054385B (es)
HR (1) HRP20020513B1 (es)
HU (1) HU230003B1 (es)
IL (2) IL150128A0 (es)
JO (1) JO2296B1 (es)
MA (1) MA26856A1 (es)
MX (1) MXPA02005560A (es)
MY (1) MY126998A (es)
NO (1) NO322240B1 (es)
NZ (1) NZ519173A (es)
PE (1) PE20011034A1 (es)
PL (1) PL200243B1 (es)
RS (1) RS50449B (es)
RU (1) RU2264398C2 (es)
TW (1) TWI274752B (es)
UY (1) UY26485A1 (es)
WO (1) WO2001044234A1 (es)
ZA (1) ZA200204258B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102373A1 (en) * 2001-06-15 2002-12-27 F. Hoffmann-La Roche Ag Method for administration of cancer therapeutic
WO2003037384A2 (en) * 2001-10-29 2003-05-08 Nektar Therapeutics Al, Corporation Polymer conjugates of protein kinase c inhibitors
WO2011084848A2 (en) * 2010-01-07 2011-07-14 Alkermes, Inc. Prodrugs of heteraromatic compounds
EP2474541A1 (en) * 2010-12-23 2012-07-11 Johannes- Gutenberg-Universität Mainz Conjugated 3-(indolyl)- and 3-(azaindolyl)-4-arylmaleimide compounds and their use in tumor treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK278989B6 (sk) 1988-02-10 1998-05-06 F. Hoffmann-La Roche Ag Substituované pyroly, ich použitie na výrobu lieči
GB9416467D0 (en) * 1994-08-13 1994-10-05 Wellcome Found Compounds for use in medicine
SI0932399T1 (sl) * 1996-03-12 2006-10-31 Pg Txl Co Lp Vodotopna paklitakselna predzdravila
TW517067B (en) * 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
PE91698A1 (es) * 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
PE91498A1 (es) * 1996-07-29 1998-12-22 Hoffmann La Roche Pirroles sustituidos
PE91598A1 (es) 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
US6943194B1 (en) * 1998-01-09 2005-09-13 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Synthesis of phenstatin and prodrugs thereof
EP1064279B1 (en) 1998-03-17 2003-06-25 F.Hoffmann-La Roche Ag Substituted bisindolylmaleimides for the inhibition of cell proliferation
US6350786B1 (en) * 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
WO2001027106A1 (en) * 1999-10-12 2001-04-19 F. Hoffmann-La Roche Ag Substituted pyrroles as antiproliferative agents for the treatment of cancer

Also Published As

Publication number Publication date
PL355856A1 (en) 2004-05-31
CZ20022447A3 (cs) 2003-06-18
JP2007153905A (ja) 2007-06-21
RU2002119209A (ru) 2004-01-10
CA2392902C (en) 2009-01-13
CN1229374C (zh) 2005-11-30
KR20020063215A (ko) 2002-08-01
AU2008201A (en) 2001-06-25
RU2264398C2 (ru) 2005-11-20
ATE306484T1 (de) 2005-10-15
KR100507422B1 (ko) 2005-08-10
NO20022776L (no) 2002-06-11
CN1409709A (zh) 2003-04-09
BRPI0016329B8 (pt) 2021-05-25
BR0016329B1 (pt) 2013-03-19
CZ304130B6 (cs) 2013-11-13
HUP0203696A3 (en) 2004-01-28
IL150128A0 (en) 2002-12-01
MY126998A (en) 2006-11-30
JP2003516986A (ja) 2003-05-20
PL200243B1 (pl) 2008-12-31
HRP20020513B1 (en) 2006-10-31
TWI274752B (en) 2007-03-01
RS50449B (sr) 2010-03-02
NO322240B1 (no) 2006-09-04
PE20011034A1 (es) 2001-10-12
GC0000265A (en) 2006-11-01
AU783616B2 (en) 2005-11-17
ZA200204258B (en) 2003-08-28
HK1054385A1 (en) 2003-11-28
NZ519173A (en) 2004-06-25
US6313143B1 (en) 2001-11-06
AR029415A1 (es) 2003-06-25
DE60023182D1 (de) 2006-02-23
NO20022776D0 (no) 2002-06-11
CO5050293A1 (es) 2001-06-27
BR0016329A (pt) 2002-08-27
WO2001044234A1 (en) 2001-06-21
HK1054385B (zh) 2006-02-17
JP4763623B2 (ja) 2011-08-31
CA2392902A1 (en) 2001-06-21
YU43302A (sh) 2005-03-15
MA26856A1 (fr) 2004-12-20
MXPA02005560A (es) 2002-09-02
ES2249314T3 (es) 2006-04-01
HUP0203696A2 (hu) 2003-03-28
HRP20020513A2 (en) 2004-08-31
DE60023182T2 (de) 2006-07-06
EP1242408B1 (en) 2005-10-12
HU230003B1 (en) 2015-04-28
JO2296B1 (en) 2005-09-12
IL150128A (en) 2006-06-11
EP1242408A1 (en) 2002-09-25

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Legal Events

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RDES Application refused

Effective date: 20180528