US20100303873A1 - Biodegradable single-phase cohesive hydrogels - Google Patents

Biodegradable single-phase cohesive hydrogels Download PDF

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Publication number
US20100303873A1
US20100303873A1 US12/746,639 US74663908A US2010303873A1 US 20100303873 A1 US20100303873 A1 US 20100303873A1 US 74663908 A US74663908 A US 74663908A US 2010303873 A1 US2010303873 A1 US 2010303873A1
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US
United States
Prior art keywords
crosslinking
gel
polymers
biodegradable single
phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/746,639
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English (en)
Inventor
Estelle Marie Piron
Guy Vitally
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Laboratoires Vivacy SAS
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Laboratoires Vivacy SAS
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Publication date
Application filed by Laboratoires Vivacy SAS filed Critical Laboratoires Vivacy SAS
Assigned to LABORATOIRES VIVACY reassignment LABORATOIRES VIVACY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PIRON, ESTELLE MARIE, VITALLY, GUY
Publication of US20100303873A1 publication Critical patent/US20100303873A1/en
Assigned to LABORATOIRES VIVACY reassignment LABORATOIRES VIVACY CHANGE OF ADDRESS Assignors: LABORATOIRES VIVACY
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/733—Alginic acid; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/594—Mixtures of polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
US12/746,639 2007-12-07 2008-12-08 Biodegradable single-phase cohesive hydrogels Abandoned US20100303873A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0759641A FR2924615B1 (fr) 2007-12-07 2007-12-07 Hydrogel cohesif biodegradable.
FR0759641 2007-12-07
PCT/EP2008/067029 WO2009071697A1 (fr) 2007-12-07 2008-12-08 Hydrogel cohésif monophasique biodégradable

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/067029 A-371-Of-International WO2009071697A1 (fr) 2007-12-07 2008-12-08 Hydrogel cohésif monophasique biodégradable

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US14/164,592 Continuation US9919076B2 (en) 2007-12-07 2014-01-27 Biodegradable single-phase cohesive hydrogels

Publications (1)

Publication Number Publication Date
US20100303873A1 true US20100303873A1 (en) 2010-12-02

Family

ID=39473297

Family Applications (5)

Application Number Title Priority Date Filing Date
US12/746,639 Abandoned US20100303873A1 (en) 2007-12-07 2008-12-08 Biodegradable single-phase cohesive hydrogels
US14/164,592 Active US9919076B2 (en) 2007-12-07 2014-01-27 Biodegradable single-phase cohesive hydrogels
US15/812,588 Active US10207024B2 (en) 2007-12-07 2017-11-14 Biodegradable single-phase cohesive hydrogels
US16/249,606 Abandoned US20190167844A1 (en) 2007-12-07 2019-01-16 Biodegradable single-phase cohesive hydrogels
US17/364,081 Pending US20210322636A1 (en) 2007-12-07 2021-06-30 Biodegradable single-phase cohesive hydrogels

Family Applications After (4)

Application Number Title Priority Date Filing Date
US14/164,592 Active US9919076B2 (en) 2007-12-07 2014-01-27 Biodegradable single-phase cohesive hydrogels
US15/812,588 Active US10207024B2 (en) 2007-12-07 2017-11-14 Biodegradable single-phase cohesive hydrogels
US16/249,606 Abandoned US20190167844A1 (en) 2007-12-07 2019-01-16 Biodegradable single-phase cohesive hydrogels
US17/364,081 Pending US20210322636A1 (en) 2007-12-07 2021-06-30 Biodegradable single-phase cohesive hydrogels

Country Status (18)

Country Link
US (5) US20100303873A1 (ja)
EP (2) EP2572702B1 (ja)
JP (2) JP5571562B2 (ja)
KR (1) KR101597333B1 (ja)
CN (1) CN101925348B (ja)
AU (1) AU2008333132B2 (ja)
BR (1) BRPI0821046B1 (ja)
CA (1) CA2708023C (ja)
EA (1) EA022478B1 (ja)
ES (2) ES2526081T3 (ja)
FR (1) FR2924615B1 (ja)
HK (1) HK1150772A1 (ja)
IL (1) IL206166A (ja)
MX (1) MX2010006248A (ja)
PL (2) PL2231108T3 (ja)
PT (2) PT2572702E (ja)
UA (1) UA99161C2 (ja)
WO (1) WO2009071697A1 (ja)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130196944A1 (en) * 2010-08-19 2013-08-01 Merz Pharma Gmbh & Co. Kgaa Filler composition comprising beta-glucans
US20130237615A1 (en) * 2010-12-06 2013-09-12 Teoxane Process of preparing a crosslinked gel
WO2013185934A1 (en) 2012-06-15 2013-12-19 Merz Pharma Gmbh & Co. Kgaa Method of preparing a composition based on hyaluronic acid
US9155757B2 (en) 2013-10-07 2015-10-13 Laboratoires Vivacy Methods and kits for treating vaginal and vulvar vestibule mucosa disorders
US9228027B2 (en) 2008-09-02 2016-01-05 Allergan Holdings France S.A.S. Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
USD750768S1 (en) 2014-06-06 2016-03-01 Anutra Medical, Inc. Fluid administration syringe
KR20160031465A (ko) * 2013-06-11 2016-03-22 앙테이스 에스.아. 하이알루론산의 가교 방법, 주사용 하이드로젤의 제조방법, 수득한 하이드로젤 및 수득한 하이드로젤의 용도
US9314530B2 (en) 2012-06-13 2016-04-19 Laboratoires Vivacy Composition, in aqueous medium, that comprises at least a hyaluronic acid and at least an hydrosoluble salt of sucrose octasulfate
US9387151B2 (en) 2013-08-20 2016-07-12 Anutra Medical, Inc. Syringe fill system and method
US9402799B2 (en) 2012-08-29 2016-08-02 Laboratories Vivacy Sterilized composition comprising at least one hyaluronic acid and magnesium ascorbyl phosphate
USD763433S1 (en) 2014-06-06 2016-08-09 Anutra Medical, Inc. Delivery system cassette
USD774182S1 (en) 2014-06-06 2016-12-13 Anutra Medical, Inc. Anesthetic delivery device
DE102017121831A1 (de) 2016-09-22 2018-03-22 Ford Global Technologies, Llc System und Verfahren zum Verlängern der Betriebszeit von Ventilaktoren eines Verbrennungsmotors
US10004824B2 (en) 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
US10500225B2 (en) 2015-12-07 2019-12-10 Kh Medtech Sárl Injectable composition; method for preparing said composition; use of said composition
US10588922B2 (en) 2015-06-24 2020-03-17 Kylane Laboratoires Sa Method for preparing an injectable cross-linked hydrogel, hydrogel obtained; and use of the obtained hydrogel
CN114129470A (zh) * 2016-02-12 2022-03-04 罗丹菲尔茨有限责任公司 保湿组合物及其用途
US11492433B2 (en) * 2018-04-23 2022-11-08 Ngk Spark Plug Co., Ltd. Hydrogel and method for producing hydrogel

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
JP2010528046A (ja) 2007-05-23 2010-08-19 アラーガン、インコーポレイテッド 架橋コラーゲンおよびその使用
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
KR101577471B1 (ko) 2007-11-16 2015-12-14 알러간, 인코포레이티드 자색반병의 치료를 위한 조성물 및 방법
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
FR2938187B1 (fr) * 2008-11-07 2012-08-17 Anteis Sa Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur
IT1395392B1 (it) * 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
WO2011110894A2 (en) 2010-03-12 2011-09-15 Allergan Industrie Sas Fluid composition for improving skin conditions
US8691279B2 (en) 2010-03-22 2014-04-08 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
KR102154944B1 (ko) 2011-06-03 2020-09-11 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
KR101421933B1 (ko) * 2012-06-19 2014-07-28 서울과학기술대학교 산학협력단 생분해성 하이브리드 하이드로젤 및 그 제조방법
WO2014198406A1 (en) 2013-06-11 2014-12-18 Anteis S.A. Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel
FR3015290B1 (fr) 2013-12-23 2017-01-13 Lab Vivacy Compositions d'acide hyaluronique compreant de la mepivacaine
AR099900A1 (es) 2014-04-01 2016-08-24 Merz Pharma Gmbh & Co Kgaa Rellenos para tejidos blandos con polisacáridos con persistencia mejorada, kit, procedimiento, uso
CN104086788B (zh) * 2014-07-17 2016-08-17 华熙福瑞达生物医药有限公司 一种注射用修饰透明质酸钠凝胶
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
TWI716365B (zh) * 2014-11-13 2021-01-21 德商梅茲製藥有限兩合公司 注射型真皮填充劑組合物及其套組、製備方法、與使用
EP3040118A1 (en) * 2014-12-29 2016-07-06 Galderma S.A. Ether cross-linked chondroitin hydrogels and their use for soft tissue applications
EP3040117A1 (en) * 2014-12-29 2016-07-06 Galderma S.A. Ether cross-linked chondroitin sulfate hydrogels and their use for soft tissue applications
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
CN104771331B (zh) * 2015-03-12 2017-12-12 华熙福瑞达生物医药有限公司 一种透明质酸弹性体及其应用
FR3036035B1 (fr) 2015-05-11 2018-10-05 Laboratoires Vivacy Compositions comprenant au moins un polyol et au moins un anesthesique
WO2017102001A1 (fr) 2015-12-16 2017-06-22 Vplus International Sa Composition d'acide hyaluronique pour injections peniennes
US10722443B2 (en) 2016-09-14 2020-07-28 Rodan & Fields, Llc Moisturizing compositions and uses thereof
FR3047666A1 (fr) 2016-02-15 2017-08-18 Benedicte Vincente Gavard Molliard Tauzin Composition injectable; procede de preparation de ladite composition; utilisation de ladite composition
KR101710639B1 (ko) * 2016-06-07 2017-03-08 주식회사 파마리서치프로덕트 핵산, 키토산 및 히알루론산을 포함하는 조직 증강용 충전 조성물 및 이의 제조방법
FR3058064B1 (fr) 2016-10-28 2020-08-07 Lab Vivacy Composition a base d'acide hyaluronique comprenant de la mepivacaine
JP6939607B2 (ja) * 2017-03-27 2021-09-22 Jsr株式会社 組成物およびその用途
CN108250462A (zh) * 2017-05-08 2018-07-06 上海利康瑞生物工程有限公司 一种抗酶解交联透明质酸钠凝胶及其制备方法和制剂
WO2018220283A1 (fr) 2017-05-29 2018-12-06 Kh Medtech Sarl Composition injectable sterile contenant de l'acide hyaluronique reticule et de l'articaine
KR101944008B1 (ko) * 2017-09-18 2019-01-30 (주) 제이씨바이오 히알루론산을 포함하는 투명 하이드로겔 막 및 이를 이용한 콘택트렌즈
FR3072026B1 (fr) * 2017-10-10 2019-10-25 Capsum Ensembles de particules, procedes de preparation et kits les comprenant
US11884765B2 (en) 2018-04-04 2024-01-30 Board Of Regents, The University Of Texas System Biodegradable elastic hydrogels for bioprinting
WO2020095079A1 (fr) * 2018-11-06 2020-05-14 Kylane Laboratoires Sa Composition injectable contenant de l'acide hyaluronique pour des applications au niveau du corps
LU101045B1 (en) 2018-12-11 2020-06-11 Qventis GmbH Method for the manufacture and use of a bionic hydrogel composition for medical applications
FR3095206B1 (fr) 2019-04-17 2021-11-05 Lab Vivacy Procede de reticulation d’un polymere
CN111249172A (zh) * 2020-01-15 2020-06-09 陈勇 一种美容注射凝胶及其制备方法
EP3854377A1 (fr) * 2020-01-22 2021-07-28 Laboratoires Genevrier Sas Composition comprenant de l'acide hyaluronique et un polyol ou de carboxyméthylcellulose
FR3111903B1 (fr) 2020-06-24 2022-12-02 Lab Vivacy Procede d’incorporation de composes organiques en solution au sein d’un hydrogel
EP4199980A1 (en) * 2020-08-18 2023-06-28 Innate S.r.l. Injectable composition and use of said composition
FR3113522A1 (fr) 2020-08-20 2022-02-25 Laboratoires Vivacy procédé d’évaluation des caractéristiques rhéologiques d’un gel
WO2023064618A1 (en) * 2021-10-15 2023-04-20 Prohibix Llc Crosslinked hyaluronic acid precipitates
FR3130132B1 (fr) 2021-12-09 2023-11-17 Oreal Dispersion comprenant une particule polymerique, un agent stabilisant a groupe cycloalkyle, une huile, et de l’eau, procede de traitement des matieres keratiniques mettant en œuvre la dispersion
FR3132220B1 (fr) 2022-01-31 2024-02-02 Oreal compositions cosmétiques perfectrices de peau et procédés d’utilisation
US20230190613A1 (en) 2021-12-09 2023-06-22 L'oreal Skin perfecting cosmetic compositions and methods of use
FR3130131B1 (fr) 2021-12-09 2023-11-17 Oreal Dispersion comprenant une particule polymerique, un agent stabilisant a groupe cycloalkyle, une huile, et un polyol, procede de traitement des matieres keratiniques mettant en œuvre la dispersion
FR3135399A1 (fr) 2022-03-30 2023-11-17 Laboratoires Vivacy émulsion comprenant un hydrogel et de la graisse ou un dérivé de graisse

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4716154A (en) * 1984-06-08 1987-12-29 Pharmacia Ab Gel of crosslinked hyaluronic acid for use as a vitreous humor substitute
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6921819B2 (en) * 2000-07-19 2005-07-26 Laboratoires D'esthetique Appliquee Polysaccharide crosslinking, hydrogel preparation, resulting polysaccharide(s) and hydrogel(s), uses thereof
WO2005085329A1 (fr) * 2004-02-03 2005-09-15 Anteis S.A. Gel reticule biocompatible
US20060194758A1 (en) * 2003-04-10 2006-08-31 Pierre Lebreton Cross-linking of low and high molecular weight polysaccharides preparation of injectable monophase hydrogels and polysaccharides and dydrogels thus obtained
US20070077292A1 (en) * 2005-10-03 2007-04-05 Pinsky Mark A Compositions and methods for improved skin care
US20070192426A1 (en) * 2002-09-17 2007-08-16 Bellsouth Intellectual Property Corporation Extending Functionality of Workflow applications using Instant Messaging (IM)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1238043A (en) 1983-12-15 1988-06-14 Endre A. Balazs Water insoluble preparations of hyaluronic acid and processes therefor
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
IT1260154B (it) * 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
FR2733427B1 (fr) * 1995-04-25 2001-05-25 W K Et Associes Compositions biphasiques injectables renfermant de l'acide hyaluronique, notamment utiles en chirurgies reparatrice et esthetique
FR2733426B1 (fr) 1995-04-25 1997-07-18 Debacker Yves Dispositif medical pour le comblement des deformations du volume de la peau telles que rides et cicatrices par injection de 2 formes physico-chimiques differentes d'un polymere biologique
JP3538741B2 (ja) * 1995-05-23 2004-06-14 独立行政法人 科学技術振興機構 複合刺激応答型生体内分解性高分子ヒドロゲル
WO1999001143A1 (en) 1997-07-03 1999-01-14 Orquest, Inc. Cross-linked polysaccharide drug carrier
FR2780730B1 (fr) * 1998-07-01 2000-10-13 Corneal Ind Compositions biphasiques injectables, notamment utiles en chirurgies reparatrice et esthetique
GB9902412D0 (en) 1999-02-03 1999-03-24 Fermentech Med Ltd Process
AU2002309026A1 (en) * 2002-05-01 2003-11-17 Hokkaido Technology Licensing Office Co., Ltd. Gel having multiple network structure and method for preparation thereof
GB0329907D0 (en) * 2003-12-23 2004-01-28 Innomed Ltd Compositions
US8293890B2 (en) * 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
WO2005112888A2 (en) * 2004-05-20 2005-12-01 Mentor Corporation Methods for making injectable polymer hydrogels
EP1779875A4 (en) 2004-06-18 2011-08-24 Univ Hokkaido Nat Univ Corp ARTIFICIAL SEMILUNAR CARTLE
JP2006013612A (ja) * 2004-06-22 2006-01-12 Traffic Shimu:Kk データ監視システム、プログラム、記録媒体、表示操作方法
US20060105022A1 (en) * 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
CN1302050C (zh) * 2005-07-07 2007-02-28 复旦大学 一种互穿网络聚合物超多孔水凝胶及其制备方法和应用
US20080317818A1 (en) * 2005-09-09 2008-12-25 May Griffith Interpenetrating Networks, and Related Methods and Compositions

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716154A (en) * 1984-06-08 1987-12-29 Pharmacia Ab Gel of crosslinked hyaluronic acid for use as a vitreous humor substitute
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6921819B2 (en) * 2000-07-19 2005-07-26 Laboratoires D'esthetique Appliquee Polysaccharide crosslinking, hydrogel preparation, resulting polysaccharide(s) and hydrogel(s), uses thereof
US20070192426A1 (en) * 2002-09-17 2007-08-16 Bellsouth Intellectual Property Corporation Extending Functionality of Workflow applications using Instant Messaging (IM)
US20060194758A1 (en) * 2003-04-10 2006-08-31 Pierre Lebreton Cross-linking of low and high molecular weight polysaccharides preparation of injectable monophase hydrogels and polysaccharides and dydrogels thus obtained
WO2005085329A1 (fr) * 2004-02-03 2005-09-15 Anteis S.A. Gel reticule biocompatible
US8052990B2 (en) * 2004-02-03 2011-11-08 Anteis S.A. Biocompatible crosslinked gel
US20070077292A1 (en) * 2005-10-03 2007-04-05 Pinsky Mark A Compositions and methods for improved skin care

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
American Academy of Orthopaedic Surgeons (AAOS) "Viscosupplementation Treatment for Arthritis" 2009 http://orthoinfo.aaos.org/topic.cfm?topic=a00217 *
Espacenet English language machine translation of FR 2733427, published October 31, 1996, IDS reference filed June 7, 2010, 2013 *

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11154484B2 (en) 2008-09-02 2021-10-26 Allergan Holdings France S.A.S. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US9228027B2 (en) 2008-09-02 2016-01-05 Allergan Holdings France S.A.S. Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US9861570B2 (en) 2008-09-02 2018-01-09 Allergan Holdings France S.A.S. Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US20150335784A1 (en) * 2010-08-19 2015-11-26 Merz Pharma Gmbh & Co. Kgaa Filler composition comprising beta-glucans
US20130196944A1 (en) * 2010-08-19 2013-08-01 Merz Pharma Gmbh & Co. Kgaa Filler composition comprising beta-glucans
US9393189B2 (en) * 2010-12-06 2016-07-19 Teoxane Process of preparing a crosslinked gel
US20130237615A1 (en) * 2010-12-06 2013-09-12 Teoxane Process of preparing a crosslinked gel
KR20130132510A (ko) * 2010-12-06 2013-12-04 테옥산 가교된 겔의 제조 공정
KR101868183B1 (ko) * 2010-12-06 2018-06-15 테옥산 가교된 겔의 제조 공정
EP2649101B1 (en) 2010-12-06 2021-06-02 Teoxane Process of preparing a cross linked gel
AU2011340106B2 (en) * 2010-12-06 2016-03-03 Teoxane Process of preparing a cross linked gel
US9314530B2 (en) 2012-06-13 2016-04-19 Laboratoires Vivacy Composition, in aqueous medium, that comprises at least a hyaluronic acid and at least an hydrosoluble salt of sucrose octasulfate
EP2861626B1 (en) * 2012-06-15 2018-12-19 Merz Pharma GmbH & Co. KGaA Method of preparing a composition based on hyaluronic acid
WO2013185934A1 (en) 2012-06-15 2013-12-19 Merz Pharma Gmbh & Co. Kgaa Method of preparing a composition based on hyaluronic acid
US9402799B2 (en) 2012-08-29 2016-08-02 Laboratories Vivacy Sterilized composition comprising at least one hyaluronic acid and magnesium ascorbyl phosphate
US10058499B2 (en) 2012-08-29 2018-08-28 Laboratoires Vivacy Sterilized composition comprising at least one hyaluronic acid and magnesium ascorbyl phosphate
KR102256061B1 (ko) 2013-06-11 2021-05-25 앙테이스 에스.아. 하이알루론산의 가교 방법, 주사용 하이드로젤의 제조방법, 수득한 하이드로젤 및 수득한 하이드로젤의 용도
US20160144043A1 (en) * 2013-06-11 2016-05-26 Anteis S.A. Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel
KR20160031465A (ko) * 2013-06-11 2016-03-22 앙테이스 에스.아. 하이알루론산의 가교 방법, 주사용 하이드로젤의 제조방법, 수득한 하이드로젤 및 수득한 하이드로젤의 용도
US9782490B2 (en) * 2013-06-11 2017-10-10 Anteis S.A. Method for crosslinking hyaluronic acid; method for preparing an injectable hydrogel; hydrogel obtained; use of the obtained hydrogel
US10010482B2 (en) 2013-08-20 2018-07-03 Anutra Medical, Inc. Syringe fill system and method
US9387151B2 (en) 2013-08-20 2016-07-12 Anutra Medical, Inc. Syringe fill system and method
US9579257B2 (en) 2013-08-20 2017-02-28 Anutra Medical, Inc. Haptic feedback and audible output syringe
US9393177B2 (en) 2013-08-20 2016-07-19 Anutra Medical, Inc. Cassette assembly for syringe fill system
US10010483B2 (en) 2013-08-20 2018-07-03 Anutra Medical, Inc. Cassette assembly for syringe fill system
US9155757B2 (en) 2013-10-07 2015-10-13 Laboratoires Vivacy Methods and kits for treating vaginal and vulvar vestibule mucosa disorders
USD774182S1 (en) 2014-06-06 2016-12-13 Anutra Medical, Inc. Anesthetic delivery device
USD763433S1 (en) 2014-06-06 2016-08-09 Anutra Medical, Inc. Delivery system cassette
USD750768S1 (en) 2014-06-06 2016-03-01 Anutra Medical, Inc. Fluid administration syringe
US10004824B2 (en) 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
US10588922B2 (en) 2015-06-24 2020-03-17 Kylane Laboratoires Sa Method for preparing an injectable cross-linked hydrogel, hydrogel obtained; and use of the obtained hydrogel
US10500225B2 (en) 2015-12-07 2019-12-10 Kh Medtech Sárl Injectable composition; method for preparing said composition; use of said composition
CN114129470A (zh) * 2016-02-12 2022-03-04 罗丹菲尔茨有限责任公司 保湿组合物及其用途
DE102017121831A1 (de) 2016-09-22 2018-03-22 Ford Global Technologies, Llc System und Verfahren zum Verlängern der Betriebszeit von Ventilaktoren eines Verbrennungsmotors
US11492433B2 (en) * 2018-04-23 2022-11-08 Ngk Spark Plug Co., Ltd. Hydrogel and method for producing hydrogel

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US20180064846A1 (en) 2018-03-08
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US20210322636A1 (en) 2021-10-21
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US20140142190A1 (en) 2014-05-22

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