UA93356C2 - Белки слияния ha ochobe rage и способы их использования - Google Patents

Белки слияния ha ochobe rage и способы их использования

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Publication number
UA93356C2
UA93356C2 UAA200702273A UAA200702273A UA93356C2 UA 93356 C2 UA93356 C2 UA 93356C2 UA A200702273 A UAA200702273 A UA A200702273A UA A200702273 A UAA200702273 A UA A200702273A UA 93356 C2 UA93356 C2 UA 93356C2
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Ukraine
Prior art keywords
rage
fusion proteins
methods
rage fusion
disclosed
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UAA200702273A
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English (en)
Ukrainian (uk)
Inventor
Аднан M.M. Мджалли
Йе E. Тянь
Джеффри K. Вебстер
Роберт Ротлейн
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Tpahctek Фарма, Инк.
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Application filed by Tpahctek Фарма, Инк. filed Critical Tpahctek Фарма, Инк.
Publication of UA93356C2 publication Critical patent/UA93356C2/ru

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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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  • Health & Medical Sciences (AREA)
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  • Ophthalmology & Optometry (AREA)

Abstract

Изобретение относится к белкам слияния на основе RAGE, которые включают полипептидные последовательности RAGE, присоединенные ко второму полипептиду, который отличается от RAGE. В белке слияния на основе RAGE может использоваться полипептидный домен RAGE, который включает сайт связывания лиганда RAGE, и междоменный линкер, непосредственно присоединенный к С2 домена иммуноглобулина. Такие белки слияния могут обеспечивать специфическое, высоко афинное связывание с лигандами RAGE. Описывается также использование белков слияния на основе RAGE как терапевтических средств при Rage-опосредованной патологии.
UAA200702273A 2004-08-03 2005-08-03 Белки слияния ha ochobe rage и способы их использования UA93356C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59855504P 2004-08-03 2004-08-03

Publications (1)

Publication Number Publication Date
UA93356C2 true UA93356C2 (ru) 2011-02-10

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ID=35149359

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200702273A UA93356C2 (ru) 2004-08-03 2005-08-03 Белки слияния ha ochobe rage и способы их использования

Country Status (23)

Country Link
US (5) US7901688B2 (ru)
EP (1) EP1781700B1 (ru)
JP (1) JP5188804B2 (ru)
KR (1) KR101323411B1 (ru)
CN (1) CN1993378A (ru)
AP (1) AP2007003869A0 (ru)
AU (1) AU2005271452B2 (ru)
BR (1) BRPI0514052A (ru)
CA (1) CA2570324C (ru)
CR (1) CR20110556A (ru)
EA (1) EA012082B1 (ru)
EC (1) ECSP077221A (ru)
ES (1) ES2473587T3 (ru)
GE (1) GEP20105110B (ru)
IL (1) IL180554A (ru)
MA (1) MA29067B1 (ru)
MX (1) MX2007001559A (ru)
NO (1) NO20065949L (ru)
NZ (1) NZ552128A (ru)
TN (1) TNSN07037A1 (ru)
UA (1) UA93356C2 (ru)
WO (1) WO2006017647A1 (ru)
ZA (2) ZA200700643B (ru)

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