UA81665C2 - Терапевтический пластырь с полисилоксановой матрицей, которая содержит капсаицин - Google Patents

Терапевтический пластырь с полисилоксановой матрицей, которая содержит капсаицин

Info

Publication number
UA81665C2
UA81665C2 UAA200510752A UAA200510752A UA81665C2 UA 81665 C2 UA81665 C2 UA 81665C2 UA A200510752 A UAA200510752 A UA A200510752A UA A200510752 A UAA200510752 A UA A200510752A UA 81665 C2 UA81665 C2 UA 81665C2
Authority
UA
Ukraine
Prior art keywords
capsaicin
therapeutic compound
topical patch
therapeutic patch
polysiloxane matrix
Prior art date
Application number
UAA200510752A
Other languages
English (en)
Ukrainian (uk)
Inventor
Вальтер Мюллер
Original Assignee
Лтс Ломанн Терапи-Системе Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лтс Ломанн Терапи-Системе Аг filed Critical Лтс Ломанн Терапи-Системе Аг
Publication of UA81665C2 publication Critical patent/UA81665C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение касается фармацевтики, в частности пластыря для местного использования, который содержит слой подкладки, непроницаемый для терапевтического соединения, самоклейкую матрицу на основе полисилоксанов, которые содержат капсаицин или терапевтическое соединение, которое является аналогом капсаицина, и защитную пленку, которую удаляют перед использованием. Матрица содержит микрорезервуары жидкости на основе амфифильного растворителя, в котором терапевтическое соединение присутствует в полностью растворенной форме, и концентрация терапевтического соединения во вкраплениях микрорезервуаров ниже, чем концентрация ее насыщенного раствора. Изобретение также касается способа изготовления пластыря и его применения при лечении невропатических болей.
UAA200510752A 2003-04-14 2003-11-19 Терапевтический пластырь с полисилоксановой матрицей, которая содержит капсаицин UA81665C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46263003P 2003-04-14 2003-04-14
PCT/EP2003/012929 WO2004089361A1 (en) 2003-04-14 2003-11-19 Therapeutic patch with polysiloxane matrix comprising capsaicin

Publications (1)

Publication Number Publication Date
UA81665C2 true UA81665C2 (ru) 2008-01-25

Family

ID=33159857

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200510752A UA81665C2 (ru) 2003-04-14 2003-11-19 Терапевтический пластырь с полисилоксановой матрицей, которая содержит капсаицин

Country Status (24)

Country Link
US (2) US8821920B2 (ru)
EP (1) EP1613297B1 (ru)
JP (1) JP4943657B2 (ru)
KR (1) KR101050672B1 (ru)
CN (2) CN101601664B (ru)
AT (1) ATE363900T1 (ru)
AU (1) AU2003289710B2 (ru)
BR (1) BRPI0318250B8 (ru)
CA (1) CA2517493C (ru)
CY (1) CY1106744T1 (ru)
DE (1) DE60314298T2 (ru)
DK (1) DK1613297T3 (ru)
ES (1) ES2288222T3 (ru)
HK (2) HK1090844A1 (ru)
IL (1) IL171249A (ru)
MX (1) MXPA05011012A (ru)
NO (1) NO337896B1 (ru)
NZ (1) NZ541956A (ru)
PL (1) PL219512B1 (ru)
PT (1) PT1613297E (ru)
RU (1) RU2349315C9 (ru)
UA (1) UA81665C2 (ru)
WO (1) WO2004089361A1 (ru)
ZA (1) ZA200506462B (ru)

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CN104546805A (zh) * 2014-12-15 2015-04-29 刘闯 一种治疗皮肤色斑的药膏贴
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KR101880442B1 (ko) * 2017-02-02 2018-07-23 대구한의대학교산학협력단 혈압 강하용 패치 조성물
WO2019043172A1 (en) * 2017-09-04 2019-03-07 Lts Lohmann Therapie-Systeme Ag TRANSDERMAL DELIVERY SYSTEM COMPRISING AN EMULSIFIER
JP2023517745A (ja) 2020-03-17 2023-04-26 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 初期非応答者を治療するためのカプサイシンパッチの繰り返しの局所適用
KR20220164022A (ko) 2020-04-03 2022-12-12 그뤼넨탈 게엠베하 캡사이신 패치의 반복된 국소 적용 요법
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Also Published As

Publication number Publication date
AU2003289710B2 (en) 2009-07-30
JP2006514977A (ja) 2006-05-18
BRPI0318250B1 (pt) 2015-08-11
WO2004089361A1 (en) 2004-10-21
CN101601664B (zh) 2012-05-23
EP1613297A1 (en) 2006-01-11
DK1613297T3 (da) 2007-09-24
US20040202707A1 (en) 2004-10-14
ATE363900T1 (de) 2007-06-15
HK1136957A1 (en) 2010-07-16
RU2349315C9 (ru) 2010-02-27
CA2517493A1 (en) 2004-10-21
EP1613297B1 (en) 2007-06-06
KR20060002997A (ko) 2006-01-09
ES2288222T3 (es) 2008-01-01
PT1613297E (pt) 2007-08-23
HK1090844A1 (en) 2007-01-05
AU2003289710A1 (en) 2004-11-01
PL378806A1 (pl) 2006-05-15
NZ541956A (en) 2008-09-26
NO337896B1 (no) 2016-07-04
PL219512B1 (pl) 2015-05-29
JP4943657B2 (ja) 2012-05-30
DE60314298D1 (de) 2007-07-19
BRPI0318250B8 (pt) 2021-05-25
IL171249A (en) 2010-06-16
ZA200506462B (en) 2006-05-31
CN100512806C (zh) 2009-07-15
KR101050672B1 (ko) 2011-07-19
RU2349315C2 (ru) 2009-03-20
CY1106744T1 (el) 2012-05-23
MXPA05011012A (es) 2005-12-12
CN1784222A (zh) 2006-06-07
DE60314298T2 (de) 2008-01-31
CA2517493C (en) 2011-05-31
RU2005134984A (ru) 2007-05-27
CN101601664A (zh) 2009-12-16
US20140335150A1 (en) 2014-11-13
BR0318250A (pt) 2006-05-23
NO20055310L (no) 2005-11-10
US8821920B2 (en) 2014-09-02

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