WO2011155542A1 - 水蒸気発生温熱具 - Google Patents
水蒸気発生温熱具 Download PDFInfo
- Publication number
- WO2011155542A1 WO2011155542A1 PCT/JP2011/063175 JP2011063175W WO2011155542A1 WO 2011155542 A1 WO2011155542 A1 WO 2011155542A1 JP 2011063175 W JP2011063175 W JP 2011063175W WO 2011155542 A1 WO2011155542 A1 WO 2011155542A1
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- Prior art keywords
- steam
- sheet
- generating
- skin
- menthol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/08—Warming pads, pans or mats; Hot-water bottles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
- A61F7/032—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
- A61F7/034—Flameless
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
- A61F2007/006—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit of gas
- A61F2007/0062—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit of gas the gas being steam or water vapour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
- A61F2007/0226—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof adhesive, self-sticking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0261—Compresses or poultices for effecting heating or cooling medicated
Definitions
- the present invention relates to a steam generating / heating device capable of imparting steam and heat to a user's body.
- Patent Document 1 discloses a thermal device in which a salve layer containing an active ingredient of a salve is provided on a contact surface with a skin of a breathable bag body in which a heat generating material that generates heat in contact with air is enclosed. It describes that chili extract or l-menthol is used as an active ingredient.
- Patent Document 2 discloses a thermal sheet having an adhesive layer and a heat generating layer containing a heat generating substance, the adhesive layer containing a thermal gel containing a polyhydric alcohol and a polymer that dissolves or swells in the polyhydric alcohol. Describes that capsaicin and l-menthol may be contained in the thermal gel.
- a warming ingredient containing a 4-hydroxy-3-methoxyphenyl group and a temperature containing a vanillylamide group such as capsaicin is known to contain a sensitive component (see Patent Document 3).
- JP 2007-136053 A JP 2003-210509 A Japanese Patent Laid-Open No. 2003-250829
- capsaicin was used by combining an excess amount of menthols and steam heat at a specific ratio with respect to the capsaicin analog, which is a warming stimulating component. Not only is the irritation peculiar to analogs alleviated and moderate warmth can be obtained, but also surprisingly, the sustainability of moderate warmth is improved, and the warmth is felt after the steam-generating warmer begins to generate heat. It has been found that the time until onset can be shortened.
- the present invention has been made on the basis of this finding, and is a steam generating warming tool having a steam generating section that discharges steam with heat generated by oxidation of an oxidizable metal, Contains capsaicin analogs and menthols,
- the present invention provides a steam generating / heating device in which the mass ratio of capsaicin analog to menthol (capsaicin analog / menthol) is 1/300 to 1/20000.
- steam generation heating tool which can be maintained for a long time of moderate warm sensation, and can shorten the time from applying a water vapor
- FIG. 1 (a) is a plan view of an embodiment of the steam generating / heating device of the present invention as seen from the body side sheet side
- FIG. 1 (b) is a sectional view taken along the line bb in FIG. 1 (a).
- FIG. 2 is a diagram showing one usage pattern of the steam generating / heating device shown in FIGS. 1 (a) and 1 (b).
- FIG. 3 is a graph showing changes in shoulder pain on the side to which the steam-generating heat tool obtained in Example 1 and Comparative Example 2 is not applied.
- FIG. 4 is a graph showing changes in skin temperature before and after application on the shoulder to which the water vapor generating warmer obtained in Example 1 and Comparative Example 2 is not applied.
- the present invention relates to a steam-generating warmer that has been further improved with respect to the warmth of the above-described prior art warmer.
- the water vapor generating / heating device of the present invention is attached to a user's body and used to give water vapor generating / heating heat accompanied with the generation of water vapor to the user's body.
- the steam generating / heating device of the present invention has a steam generating section.
- the water vapor generating part contains an oxidizable metal and water, and is configured to release water vapor as heat is generated by oxidation of the oxidizable metal.
- the steam generating / heating device of the present invention is characterized in that capsaicin analogues, menthols, steam and heat are used in combination.
- the capsaicin analog refers to capsaicin and analogs thereof, and specifically refers to those represented by the general formula (1). Specifically, in addition to capsaicin, dihydrocapsaicin, nordihydrocapsaicin, homodihydrocapsaicin, homocapsaicin, bishomocapsaicin, trishomocapsaicin, nornorcapsaicin, norcapsaicin, capsaicinol, nonylic acid vanillylamide, decylic acid vanillylamide, etc.
- capsaicin analogs are capsaici and dihydrocapsaicin.
- the present inventors can not only obtain an appropriate warm feeling by using an excessive amount of menthols in combination with capsaicin analog, which is a warming stimulating component, but surprisingly, it is applied to the body. It has been found that the time from onset to onset of warmth can be shortened and the sustainability of moderate warmth is improved. In addition, the present inventors have found that not only the site to which the steam generating / heating tool is applied but also the site to which the steam generating / heating tool is not applied has an effect of increasing the skin temperature or improving pain.
- menthol refers to l-menthol and dl-menthol. A particularly preferred menthol is l-menthol.
- Capsaicin analogs can be used singly or in combination of two or more. Menthols can also be used singly or in combination of two or more.
- the mass ratio of capsaicin analogs to menthols is set to 1/300 to 1/20000 in the steam generating warmer of the present invention. is doing.
- the capsaicin analog / menthol ratio is within this range, the heat of the capsaicin analog is affected by stimulation of highly volatile menthols and steam heat, resulting in rapid onset of warmth.
- the mass ratio is preferably 1/500 to 1/15000, and more preferably 1/1000 to 1/7000.
- the capsaicin analog and menthol may be present in a mixed state, but the capsaicin analog and menthol are present separately in separate parts of the steam generating heater. From the viewpoint of making the above-mentioned effects remarkable and the viewpoint of storage stability, it is very preferable.
- the capsaicin analog it is preferable that the capsaicin analog is present in a part that can be transferred to the user's skin by direct contact, for example, a member that is in direct contact with the user's skin among the members of the steam-generating / heating device of the present invention.
- menthols it is better to make them exist in the member which does not touch a user's skin among the members of the steam generation heating tool of the present invention. Since the steam generating / heating device of the present invention is accompanied by the generation of water vapor, even if menthols are present in a member away from the user's skin, the menthols are accompanied by the flow of water vapor due to their volatilization and are successfully. Reach even the user's skin.
- menthol is preferably present in a water vapor generating part (hereinafter also referred to as a heat generating part). The reason will be described later.
- FIG. 1 shows an embodiment of the steam generating / heating device of the present invention.
- the steam generating / heating device 10 is flat and includes a packaging material 20 and a heat generating portion 30 hermetically housed in the packaging material 20.
- the packaging material 20 forms the outer shape of the water vapor generating warming tool 10 and has a flat shape.
- the packaging material 20 has a skin-facing surface that faces the user's skin when using the water vapor generating warming tool 10, and an outer surface that faces the outside when used.
- the skin facing surface is composed of a body side sheet 21.
- the outer surface is composed of the outer sheet 22.
- the body side sheet 21 and the outer sheet 22 have substantially the same shape, and the peripheral area 23 of both the sheets 21 and 22 is hermetically joined by a predetermined means.
- the heat generating part 30 is covered at least partially with a sheet having air permeability. Specifically, the heat generating unit 30 is covered with a first sheet 31 that faces the user's skin when using the steam generation warming tool 10 and a second sheet 32 that faces the outside when used. The first sheet 31 and / or the second sheet 32 has air permeability at least in part.
- seat 32 are substantially the same shape, and the peripheral part (not shown) of both the sheets 31 and 32 is sealingly joined by the predetermined
- the oxidizable metal contained in the heat generating part 30 generates oxidative heat when it comes into contact with oxygen that has permeated through the gas-permeable portion of the sheet 31 and / or the sheet 32.
- the water vapor is preferentially released through the first sheet 31 by appropriately adjusting the air permeability of the first sheet 31 and the second sheet 32.
- the air permeability of the second sheet 32 is larger than the air permeability of the first sheet 31.
- the air permeability is a value measured by JIS P8117, and is defined as the time required for 100 ml of air to pass through an area of 6.42 cm 2 under a constant pressure. Therefore, a large air permeability means that it takes time to pass air, that is, the air permeability is low. Conversely, a low air permeability means that the air permeability is high.
- the magnitude of the air permeability and the level of air permeability are opposite to each other.
- the first sheet 31 is the same as or higher than the second sheet 32.
- the air permeability of the first sheet 31 is preferably 100 to 30000 seconds / 100 ml, more preferably 500 to 20000 seconds / 100 ml, and still more preferably 1000 to 10,000 seconds / 100 ml.
- the second sheet 32 is permeable or non-permeable, and if it is permeable, the value is equal to or higher than the air permeability of the first sheet 31 and is 8000. Those having a molecular weight of ⁇ 100,000 seconds / 100 ml are preferred, those having 10,000 to 90,000 seconds / 100 ml are more preferred, and those having 15,000 to 80,000 seconds / 100 ml are more preferred.
- An adhesive 24 is applied to the surface of the body side sheet 21 in the packaging material 20 of the steam generating / heating device 10.
- the adhesive 24 is used as a means for fixing the water vapor generating warming tool 10 to the user's body.
- the adhesive 24 is formed at a position where it does not overlap the heat generating part 30 in a plan view of the water vapor generating warming tool 10.
- the adhesive 24 is applied continuously or discontinuously at the position of the peripheral region of the body side sheet 21 so as to surround the heat generating portion 30.
- region where the adhesive 24 is given may be contained in the joining area
- the sheet can be held without being peeled off during use, and is generated from the heat generating part 30 particularly when continuously applied so as to surround the heat generating part 30 over the entire periphery.
- steam outside is preferable, For example, it selects from hot melt adhesives, such as conventionally well-known natural or synthetic rubber type
- a tackifier, a softener, an inorganic filler, an anti-aging agent, an ultraviolet absorber, a pigment, and the like that are added to a general pressure-sensitive adhesive may be added within a range not impairing the effects of the present invention.
- the body side sheet 21 has air permeability and can release water vapor.
- examples of such materials include fiber sheets, porous films, perforated films, and the like.
- the sheet 21 is preferably one having a good texture.
- the sheet 21 is polyester, polyolefin, polyamide, poly Using synthetic fibers made of acrylic, natural fibers made of cellulose, cotton, wool, silk, etc., or composite fibers of these, etc., air-through method, spunbond method, needle punch method, melt blown method, card method, thermal fusion It is preferable that it consists of the nonwoven fabric manufactured by the attachment method, the hydroentanglement method, the solvent adhesion method, etc.
- the steam generated from 30 is used, it is preferable for the steam generated from 30 to be effectively applied to the skin and to suitably exhibit the effect of shortening the expression of warmth and the effect of improving the sustainability of an appropriate warmth of the present invention.
- the outer sheet 22 may or may not have air permeability depending on a specific application of the steam generating / heating device 10.
- an appropriate material may be selected depending on whether it is air permeable or not.
- the capsaicin analog is held on at least the surface that is the contact surface of the body-side sheet 21 that is a member that directly contacts the user's skin when used.
- the capsaicin analog is the absence of the adhesive 24 in the body side sheet 21, that is, the body side sheet 21. It is preferable to be held in the central region. In particular, it is preferable that the capsaicin analog is held at a position overlapping the heat generating portion 30 in a plan view of the water vapor generating warming tool 10 from the viewpoint of appropriate warmth.
- the capsaicin analog on the body side sheet 21 As a means for holding the capsaicin analog on the body side sheet 21, an appropriate means may be adopted according to the material of the body side sheet 21.
- the body-side sheet 21 is made of, for example, a non-woven fabric, a capsaicin analog is dispersed and supported between the fibers when the non-woven fabric is manufactured, or a liquid agent in which the capsaicin analog is dispersed and mixed is applied to the surface of the non-woven fabric.
- Capsaicin analogs can be successfully held by working or impregnating with a nonwoven fabric.
- the capsaicin analog is dispersed and supported between the fibers when the nonwoven fabric is manufactured, or the capsaicin analog is dispersed and mixed on the surface of the nonwoven fabric. It is possible to successfully hold the capsaicin analog by coating the prepared liquid agent or impregnating the nonwoven fabric.
- the amount of capsaicin analog to be held on the body-side sheet 21 is 0.05 based on the area of the site to which the capsaicin analog is applied from the viewpoint that the strength of warm feeling due to the capsaicin analog is a preferable level. preferably in the ⁇ 5.0 ⁇ g / cm 2, more preferably be 0.08 ⁇ 3.0 ⁇ g / cm 2.
- the position of the menthol may be held on the body side sheet 21 as with the capsaicin analog, or other members such as the heat generating portion 30, the sheet 31, the sheet 32, or the outer sheet 22 may be used. You may make it hold. Considering the stability of menthols during storage of the steam-generating warmer 10 and the ease of retaining menthols, it is preferable to retain them in the heat generating part 30.
- the amount of menthols to be held in the steam generating / heating device 10 is preferably such that the mass ratio between the capsaicin analog and the menthols satisfies the above range, and is 0.05 to 10 mg / cm 2 . More preferably, it is 0.1 to 5.0 mg / cm 2 .
- the ratio of menthols to the heat generating part 30 is preferably 0.02 to 5.0% by mass, particularly 0.04 to 2.5% by mass. .
- the menthols When the menthols are held in the heat generating part 30, it is preferable to add the menthols to the heat generating part 30 together with a dissolving agent for dissolving the menthols.
- a dissolving agent for dissolving the menthols.
- the solubilizer is preferably an organic solvent that can dissolve oily substances and is harmless to the body.
- the dissolving agent is an organic solvent having good compatibility with water.
- the solubilizer can be uniformly distributed in the heat generating portion 30.
- an organic solvent include alcohols which are liquid substances at 25 ° C., for example, polyethylene glycol such as ethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, polyethylene glycol 200 and polyethylene glycol 400.
- examples thereof include polyhydric alcohols such as glycol, polypropylene glycol and 1,3-propanediol, and lower alcohols such as ethanol.
- a liquid polyhydric alcohol is particularly preferable at 25 ° C. in that a large amount of menthol is released.
- this invention accompanies the heat_generation
- polyethylene glycol and propylene glycol are preferred because they can effectively enhance the release of menthols.
- the dissolving agent may be used alone or in combination of two or more.
- the menthol is sufficiently dissolved and added so as to spread uniformly over the entire heat generating portion 30, and from the viewpoint of further reducing the influence on the heat generating characteristics, the dissolving agent is used with respect to the total weight of the heat generating portion 30.
- the concentration is preferably 0.01 to 20% by mass, more preferably 0.1 to 10% by mass, and still more preferably 0.5 to 5% by mass.
- the solubilizer when the total mass of the solubilizer and menthol is 100, the solubilizer is preferably 5 to 99% by mass, more preferably 10 to 93% by mass, and still more preferably. 30 to 90% by mass, most preferably 50 to 80% by mass is used.
- a solution in which menthols are dissolved in a dissolving agent in advance is prepared, and after the heat generating part 30 is prepared, the solution may be added.
- the addition method include spraying, coating, and dipping methods.
- menthols As another method for holding menthols in the heat generating part 30, it is also preferable to add the menthols to the heat generating part 30 together with a solubilizing agent and a surfactant that dissolve them.
- a solubilizing agent As another method for holding menthols in the heat generating part 30, it is also preferable to add the menthols to the heat generating part 30 together with a solubilizing agent and a surfactant that dissolve them.
- A) 1st solubilizer consisting of one or two or more liquid oils at 25 ° C. selected from the group consisting of hydrocarbon oils, ester oils, monohydric alcohols, fatty acids, silicone oils, glycerides and vegetable oils
- Second solubilizer comprising a polyhydric alcohol
- the first solubilizer examples include hydrocarbon oils such as liquid paraffin and squalane, ester oils such as isopropyl myristate, isopropyl palmitate, cetyl 2-ethylhexanoate, octyldodecyl myristate, and neopentyl glycol dicaprate.
- hydrocarbon oils such as liquid paraffin and squalane
- ester oils such as isopropyl myristate, isopropyl palmitate, cetyl 2-ethylhexanoate, octyldodecyl myristate, and neopentyl glycol dicaprate.
- Monovalent alcohols such as 2-hexyldecanol, 2-octyldodecanol, 2-decyltetradecanol and isostearyl alcohol, fatty acids such as isostearic acid and oleic acid, cyclics such as dimethylpolysiloxane, methylphenylpolysiloxane and cyclomethicone Or linear silicone oil, monoglyceride such as dioleic acid diglyceride, diglyceride such as diethylhexyl monoglyceride, glyceryl tricaprylate, tri (caprylic acid / capric acid Triglycerides such as glycerol, jojoba oil, macadamia nut oil, olive oil, vegetable oil such as castor oil and the like.
- monohydric higher alcohols having 16 to 22 carbon atoms have high compatibility with menthols, so that menthols can be uniformly mixed in the heat generating portion 30 with a smaller amount. For this reason, the influence on the heat generation is reduced, and generation of a strange odor or the like is not observed during the heat generation, which is particularly preferable.
- the first solubilizer is preferably contained in the heat generating portion 30 in a proportion of 0.01 to 5% by mass, more preferably 0.05 to 3% by mass, and particularly preferably 0.1 to 1% by mass. A sufficient calorific value is ensured.
- the mass ratio of the first solubilizer to the menthols is preferably 0.01 to 2.0, more preferably 0.05 to 1.0, and still more preferably 0.00. 1 to 0.5.
- polyhydric alcohol used as the second solubilizer examples include ethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, polyethylene glycol such as polyethylene glycol 200 and polyethylene glycol 400, polypropylene glycol, 1 , 3-propanediol and the like.
- polyethylene glycol is preferably used because it can effectively enhance the release of menthols while maintaining the emulsifying dispersibility of the menthols by the surfactant.
- the second solubilizer is preferably contained in the heat generating portion 30 in a proportion of 0.01 to 5% by mass, more preferably 0.05 to 3% by mass, and particularly preferably 0.1 to 2% by mass. This is preferable because a sufficient calorific value is ensured and the menthol release from the heat generating portion 30 is improved.
- the combination of solubilizers is selected in consideration of the compatibility between menthols and water and the degree of influence on the affinity between the surfactant and water. That is, a preferred combination of the first solubilizer and the second solubilizer is a combination using a monovalent higher alcohol as the first solubilizer and using a polyhydric alcohol as the second solubilizer. By using this combination, menthols and water in the heat generating part 30 are more emulsified, inhibition of heat generation is minimized, and good release of menthols during heat generation is achieved. Specifically, 2-octyldodecanol, 2-hexyldecanol and the like are particularly preferably used as the first solubilizer. On the other hand, polyethylene glycol, particularly polyethylene glycol having a molecular weight of 200 to 600, is particularly preferably used as the second solubilizer.
- cationic surfactants As surfactants used together with menthols and the above-mentioned solubilizers, cationic surfactants, anionic surfactants, nonionic surfactants and amphoteric surfactants can be used as long as they can be used in cosmetics, pharmaceuticals and the like. Any of the agents can be used. Among them, the aqueous electrolyte solution and menthol contained in the heat generating part 30 can be successfully emulsified, the emulsification stability is high, and the menthols can be favorably released by the heat generation of the heat generating part 30; and From the viewpoint that it is difficult to inhibit the heat generation of the heat generating portion 30, it is advantageous to use a nonionic surfactant.
- Nonionic surfactants include polyoxyethylene alkyl ether, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl allyl ether, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid ester, fatty acid monoglyceride, poly Oxyethylene fatty acid ester, polyoxyethylene alkylamine, alkyl alkanolamide, sucrose fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene fatty acid glycerin, polyoxyethylene polyoxypropylene copolymer and the like can be used.
- polyoxyethylene surfactants such as polyoxyethylene alkyl ether, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl allyl ether, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid Esters, polyoxyethylene fatty acid esters, polyoxyethylene alkylamines, polyoxyethylene fatty acid glycerin, polyoxyethylene polyoxypropylene copolymers, etc., especially polyoxyethylene hydrogenated castor oil and polyoxyethylene alkyl ether It is preferable because it interacts with the solubilizer and acts on the affinity of the surfactant with water.
- polyoxyethylene hydrogenated castor oil or polyoxyethylene alkyl ether having HLB of preferably 10 to 20, more preferably 12 to 18, and more preferably 13 to 17, particularly polyoxyethylene hydrogenated castor oil may be used.
- the HLB value is obtained from the Griffin equation (J. Soc. Cosmet. Chem., 1, 311 (1949)).
- the content of the surfactant in the heat generating part 30 is preferably 0.01 to 5% by mass, more preferably 0.05 to 3% by mass, and particularly preferably 0.1 to 2% by mass.
- the menthols and the solubilizer are more preferably dispersed in the heat generating part 30, so that the menthols can be blended more uniformly in the heat generating part 30. It is preferable that menthols can be released satisfactorily due to the heat generation and the influence on the heat generation is reduced.
- the mass ratio of the second solubilizer / surfactant is preferably 0.1 to 5, more preferably 0.5 to 2, in relation to the content of the second solubilizer.
- the amount of the surfactant used is within this range, the heat generation of the heat generating part 30 is more difficult to be inhibited, and the emulsification stability between menthols and water contained in the heat generating part 30 is further increased, and Good release of menthols is achieved.
- the adhesive 24 is applied to the peripheral area located outside the central area of the body side sheet 21 to form an adhesive layer.
- this pressure-sensitive adhesive layer is continuously formed so as to surround the central area
- the central area of the body side sheet 21 is It is sealed by the adhesive layer existing in the peripheral area. That is, the sealed portion is defined by the user's skin, the central region of the body-side sheet 21, and the adhesive layer present in the peripheral region.
- the sealed portion is filled with water vapor generated from the heat generating portion 30 and is also filled with volatilized menthol.
- the capsaicin analog is also transferred from the central region of the body side sheet 21 to the user's skin by direct contact.
- the steam generation warming tool 10 has a sufficient amount of steam generation. From this point of view, the steam generating / heating device 10 generates 5 to 50 mg / (cm 2 ⁇ 60 min) of water vapor generated for 60 minutes per unit area and applied to the skin for 5 hours after application to the body. In particular, it is preferably 6 to 40 mg / (cm 2 ⁇ 60 min), more preferably 8 to 35 mg / (cm 2 ⁇ 60 min).
- the amount of water vapor generated is measured as follows. A tester with a volume of 4.2 liters and a humidity of 1 RH% or less and capable of supplying 2.1 liters / min of dry air in a sealed system is prepared. The warming tool 10 is left to generate heat. And the humidity of the air discharged
- e is a water vapor pressure (Pa)
- es is a saturated water vapor pressure (Pa: quoted from JIS Z8806)
- T is a temperature (° C .: dry bulb temperature)
- s is a sampling period (seconds).
- the air permeability (JIS P8117) of the first sheet 31 and the second sheet 32 covering the heat generating portion 30 may be appropriately balanced.
- the air permeability of the first sheet 31 and the second sheet 32 is compared, the air permeability of the first sheet 31 that is a sheet disposed on the side facing the wearer's body is 2nd.
- the steam-generating warming tool 10 has an exothermic temperature in addition to the sufficient amount of steam generated. Is also sufficient.
- the steam generating / heating device 10 has a heat generation characteristic such that the skin surface temperature is maintained at 38 to 43 ° C. for 1 to 5 hours in a state where the steam heating and heating device 10 is in direct contact with the user's skin. Preferably it is.
- the skin surface temperature is measured at a position directly below the heat generating part in the water vapor generating warming tool 10 attached to the subject's body (for example, the back part of the neck or the shoulder part).
- a body temperature monitor (Core Temp CM-210: manufactured by Terumo Corp., body surface temperature probe: PDK161) is used to measure the skin surface temperature immediately below the heat generating part.
- the steam generating / heating device 10 having the above-described characteristics of the amount of water vapor and the heat generation temperature, the content of the oxidizable metal and water mainly contained in the heat generating portion 30 and the permeability of the sheet 31 covering the heat generating portion 30 are obtained. What is necessary is just to control values, such as a temperament.
- the oxidizable metal contained in the heat generating part 30 the same ones that are usually used in the technical field including iron powder can be used.
- the components constituting the heat generating unit 30 appropriate components are used according to the structure of the heat generating unit 30.
- a heat generating sheet configured by injecting an electrolytic solution containing an electrolyte and water into a molded body containing, for example, an oxidizable metal and a reaction accelerator can be used.
- a heat-generating powder comprising an oxidizable metal, a reaction accelerator, an electrolyte, and water can be used.
- the content of the electrolyte and water is 0.3 to 10% by weight, more preferably 0.5 to 7% by weight with respect to 100 parts by weight of the molded body containing the oxidizable metal, the reaction accelerator or the like. It is preferable that 20 to 80 parts by weight of an aqueous electrolyte solution containing% electrolyte is contained.
- the steam generating / heating device 10 of the present embodiment can be used by directly sticking to the user's skin. Since the steam generation warming tool 10 has a quick rise in warm feeling and good sustainability of an appropriate warm feeling as compared with a conventional heating tool, it can be locally heated with a small size. . Since the small-sized heating tool 10 has a smaller content of oxidizable metal, the total calorific value tends to be smaller than that of a large-sized one, and as a result, a warm feeling is obtained for a sufficient time. There is concern that it will not be possible. However, even such a small-sized heating tool 10 is very preferable because an appropriate warmth can be maintained by the combined use of capsaicin analogs and menthols.
- the heating tool 10 of the present embodiment has a small area of, for example, preferably 1.0 to 30 cm 2 , more preferably 2.0 to 20 cm 2 when the area of the heating unit 30 in plan view is small. When it has, the characteristic is exhibited notably.
- the shape of the steam generating / heating device 10 is not limited to that shown in FIG. 1, and various shapes such as a circle, an ellipse, a polygon other than a rectangle, and combinations thereof can be employed.
- steam generation heating tool 10 is not restricted to the site
- a steam generating / heating device 10 according to the embodiment shown in FIG. 2 was produced by the following procedure.
- Polyamide epichlorohydrin resin manufactured by Seiko PMC Co., Ltd., trade name “WS4020” based on 100 parts of the solid content (total of oxidizable metal, fibrous material and activated carbon) of the raw material composition. And 0.78 parts of sodium carboxymethylcellulose (Daiichi Kogyo Seiyaku Co., Ltd., trade name “HE1500F”) as an anionic flocculant was added. The slurry was added until the concentration reached 12%.
- ⁇ Drying conditions> The molded sheet was sandwiched with felt and dehydrated under pressure, passed through a heating roll at 140 ° C. as it was, and dried until the water content became 5% or less.
- the basis weight after drying was 450 g / m 2 and the thickness was 0.45 mm.
- the composition of the molded sheet thus obtained was measured using a thermogravimetric measuring apparatus (TG / DTA6200, manufactured by Seiko Instruments Inc.), and as a result, it was 83% iron, 9% activated carbon, and 8% pulp.
- ⁇ Preparation of the sheet-like heating part 30> The obtained molded sheet was cut into 25 mm ⁇ 25 mm, four sheets were stacked, and 40 parts of a menthol-containing electrolyte prepared with the composition shown in Table 1 was injected into 100 parts of the molded sheet.
- the ratio of menthol to the total mass of the heat generating part 30 is 0.9%
- the ratio of 2-octyldodecanol is 0.2%
- the ratio of polyethylene glycol 400 is 1.4%
- polyoxyethylene hydrogenated castor oil (60 EO .) (HLB14.0) was 0.9%.
- the air permeability (JIS P8117) of the air permeable film 31 on the skin facing surface side was 2500 seconds / 100 ml, and the air permeability (JIS P8117) of the outer air permeable film 32 was 30000 seconds / 100 ml.
- capsicin analog (capsaicin, dihydrocapsaicin, etc.) 0.032 g / 100 ml of chili pepper tincture is mixed with ethanol as a volatile solvent, uniformly dispersed, and the solution is applied to the nonwoven fabric. Thereafter, it was held by a drying method.
- the holding amount was 0.54 ⁇ g / cm 2 and the holding area was 7.5 cm 2 .
- the hot melt adhesive which consists of a SIS copolymer was continuously applied to the peripheral area of the body side sheet 21. The coating area was 15 cm 2 .
- the target water vapor generation heating tool 10 was obtained.
- Example 2 A steam generating and heating tool 10 was obtained in the same manner as in Example 1 except that the amount of menthol retained in Example 1 was 0.24 mg / cm 2 .
- Example 3 A steam generating and heating tool 10 was obtained in the same manner as in Example 1 except that the amount of menthol retained in Example 1 was 0.53 mg / cm 2 .
- Example 4 A water vapor generating warming tool 10 was obtained in the same manner as in Example 1 except that the amount of menthol retained in Example 1 was 3.90 mg / cm 2 .
- Example 5 In Example 1, similarly to the capsaicin analog, the water vapor generating warming tool 10 was obtained in the same manner as in Example 1 except that the menthol was also held on the outer sheet 22.
- Example 6 the steam generation heating tool 10 was obtained in the same manner as in Example 1 except that the amount of capsaicin analog retained was 1.3 ⁇ g / cm 2 .
- Example 7 In Example 1, the water vapor generation heating tool 10 was obtained in the same manner as in Example 1 except that the amount of capsaicin analog retained was 0.13 ⁇ g / cm 2 .
- Example 8 In Example 1, the air permeability of the first sheet 31 was changed to 10000 seconds / ml, the air permeability of the second sheet 32 was changed to 10,000 seconds / ml, and the water vapor generation amount was 7.3 mg / ( Except for setting it as cm ⁇ 2 > * 60min), it carried out similarly to Example 1, and obtained the water vapor
- Example 1 This comparative example is an example of a dry heat heater.
- the electrolytic solution when manufacturing the heat generating part 30, the electrolytic solution was injected so that the amount of electrolytic solution (5.0% saline) was 40 parts with respect to 100 parts of the molded sheet. Except this, it carried out similarly to Example 1, and obtained the heating tool of dry heat.
- Comparative Example 2 This comparative example is an example in which menthols are not used.
- a water vapor generating warming tool was obtained in the same manner as in Example 1 except that menthol was not used.
- the skin irritation intensity was evaluated by three professional panelists.
- Non-applied shoulder pain level (before application) [(Non-applicable shoulder pain current value (before application) ⁇ current perception threshold) / current perception threshold] ⁇ 100 (1) 3)
- the right forearm was pressed with a constant pressure (4.5 kg / 15 mm ⁇ ) with a push-pull gauge (manufactured by Aiko Engineering Co., Ltd.) to generate pain.
- the two electrode pads were separated by 2 cm and an electric current was applied to gradually increase the current value.
- the current value at that time was defined as “right forearm pain corresponding current value (before application)”.
- the pain level was calculated according to the following formula (2), and this value was defined as “right forearm pain level (before application)”.
- Non-applied shoulder relative pain level (before application) (Non-applied shoulder pain level (before application) / right forearm pain level (before application)) ⁇ 100 (3) 5) Non-applied shoulder relative pain (after application) calculation After applying the heating tool to one shoulder for 3 hours, perform the same operation as 2) to 4), and apply the other heating tool that has not been applied.
- the “non-applied shoulder pain level (after application)” and “right forearm pain level (after application)” of the shoulder (non-applied shoulder) were measured, and the non-applied shoulder relative pain level (after application) was calculated.
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Abstract
Description
カプサイシン類縁体及びメントール類を含有し、
カプサイシン類縁体とメントール類との質量比(カプサイシン類縁体/メントール類)を1/300~1/20000とした水蒸気発生温熱具を提供するものである。
・A)炭化水素油、エステル油、一価のアルコール、脂肪酸、シリコーン油、グリセライド及び植物油よりなる群から選ばれる1種又は2種以上の25℃で液状の油剤からなる第1の溶解剤
・B)多価アルコールからなる第2の溶解剤
相対湿度U(%RH)=(e/es)×100
絶対湿度D(g/m3)=(0.794×10-2×e)/(1+0.00366T)
=(0.794×10-2×U×es)/〔100×(1+0.00366T)〕
単位空気容積P(リットル)=(2.1×s)/60
単位時間当たりの水蒸気の発生量A(g)=(P×D)/1000・・・(1)
なお、ここで言う水蒸気発生量とは、第1のシート31及びその外側に位置する身体側シート21を透過して肌に付与される水蒸気量のことを言う。第1のシート31と第2のシート32の透気性とが異なる場合には、両者の透気度の比による重みづけをして、肌に付与される水蒸気の発生量を算出する。
図2に示す実施形態の水蒸気発生温熱具10を、以下の手順で作製した。
(1)シート状発熱部30の作製
<原料組成物配合>
・被酸化性金属:鉄粉、同和鉱業株式会社製、商品名「RKH」:83%
・繊維状物:パルプ繊維(フレッチャー チャレンジ カナダ社製、商品名 NBKP「Mackenzi(CSF200mlに調整)」):8%
・反応促進剤:活性炭(日本エンバイロケミカル株式会社製、商品名「カルボラフィン」、平均粒径45μm)9%
前記スラリーを用い、これを抄紙ヘッドの直前で0.3%に水希釈し、傾斜型短網抄紙機によって、ライン速度15m/分にて抄紙して湿潤状態の成形シートを作製した。
成形シートをフェルトで挟持して加圧脱水し、そのまま140℃の加熱ロール間に通し、含水率が5%以下になるまで乾燥した。乾燥後の坪量は450g/m2、厚さは0.45mmであった。このようにして得られた成形シートの組成を熱重量測定装置(セイコーインスツルメンツ社製、TG/DTA6200)を用いて測定した結果、鉄83%、活性炭9%、パルプ8%であった。
得られた成形シートを25mm×25mmに切り取り、4枚を重ね合わせ、該成形シート100部に対し表1に示す組成で調製したメントール類含有電解液を40部注入した。発熱部30の全質量に対するメントールの割合は0.9%、2-オクチルドデカノールの割合は0.2%、ポリエチレングリコール400の割合は1.4%及びポリオキシエチレン硬化ヒマシ油(60E.O.)(HLB14.0)の割合は0.9%であった。毛管現象を利用してこれらを成形シート全体に浸透させて、矩形のシート状発熱部30(寸法25mm×25mm)を得た。このときのシート状発熱部30中のメントール量は2.18mg/cm2であった。このシート状発熱部30の全体を、ポリエチレン製透気フィルムで包んだ。この透気フィルムは、肌対向面側と外側とで通気度が異なるものを用いた。肌対向面側の透気フィルム31の透気度(JIS P8117)は2500秒/100mlであり、外側の透気フィルム32の透気度(JIS P8117)は30000秒/100mlであった。
包材20における身体側シート21として、ポリエチレンテレフタレート繊維からなるニードルパンチ不織布(坪量40g/m2)を用いた。外側シート22として、坪量50g/m2のポリプロピレン不織布を用いた。これらのシートからなる包材20内に、上述のポリエチレン製透気フィルム31,32で包まれた発熱部30を収容した。身体側シート21の中央域には、カプサイシン類縁体(カプサイシン及びジヒドロカプサイシン等)を0.032g/100ml含むトウガラシチンキを、揮発溶媒であるエタノールに混合し均一分散させ、該溶液を不織布に塗布し、その後、乾燥させる方法によって保持させた。保持量は0.54μg/cm2、保持面積は7.5cm2とした。また、身体側シート21の周縁域には、SIS共重合体からなるホットメルト粘着剤を連続して塗工した。塗工面積は15cm2とした。このようにして、目的とする水蒸気発生温熱具10を得た。
実施例1においてメントールの保持量を0.24mg/cm2とする以外は実施例1と同様にして水蒸気発生温熱具10を得た。
実施例1においてメントールの保持量を0.53mg/cm2とする以外は実施例1と同様にして水蒸気発生温熱具10を得た。
実施例1においてメントールの保持量を3.90mg/cm2とする以外は実施例1と同様にして水蒸気発生温熱具10を得た。
実施例1において、カプサイシン類縁体と同様に、メントールも外側シート22に保持させた以外は実施例1と同様にして水蒸気発生温熱具10を得た。
実施例1において、カプサイシン類縁体の保持量を1.3μg/cm2とする以外は実施例1と同様にして水蒸気発生温熱具10を得た。
実施例1において、カプサイシン類縁体の保持量を0.13μg/cm2とする以外は実施例1と同様にして水蒸気発生温熱具10を得た。
実施例1において、第1のシート31の透気度を10000秒/ml、第2のシート32の透気度を10000秒/mlのように変更して、水蒸気発生量を7.3mg/(cm2・60min)とする以外は、実施例1と同様にして水蒸気発生温熱具10を得た。
本比較例は、乾熱の温熱具の例である。実施例1において、発熱部30を製造するときに、成形シート100部に対し電解液量(5.0%食塩水)が40部となるように、電解液を注入した。これ以外は実施例1と同様にして乾熱の温熱具を得た。
本比較例は、メントール類を使用しない例である。実施例1においてメントールを使用しない以外は実施例1と同様にして水蒸気発生温熱具を得た。
本比較例は、メントール類を超大過剰に使用した例である。メントールを超大過剰に使用した以外は実施例6と同様にして水蒸気発生温熱具を得た。
実施例及び比較例で得られた温熱具について、以下の方法で温感の発現の早さ、適度な温感の持続性、皮膚刺激感強度を評価した。また、上述の方法で水蒸気の発生量及び肌表面温度を測定した。それらの結果を以下の表2に示す。
専門パネラー3名による温感の発現の早さの評価を行った。実施例及び比較例の水蒸気発生温熱具及び乾熱の温熱具を肩部に3時間適用した際の温感強度を「0:感じない」「1:弱く感じる」「2:やや弱く感じる」「3:ちょうどよく感じる」「4:やや強く感じる」「5:強く感じる」の6段階で評価し、温感の経時変化を検討した。温感発現の早さは、温熱具を肩部に適用してから温感を「1:弱く感くじる」までの時間を測定し、平均値を求めた。
専門パネラー3名による適度な温感の持続性の評価を行った。実施例及び比較例の水蒸気発生温熱具及び乾熱の温熱具を肩部に3時間適用した際の温感の強度を「0:感じない」「1:弱く感じる」「2:やや弱く感じる」「3:ちょうどよく感じる」「4:やや強く感じる」「5:強く感じる」の6段階で評価し、温感の経時変化を検討した。適度な温感の持続性は、温感の強度が「2:やや弱く感じ」から「4:やや強く感じる」の間に維持される時間を測定し、平均値を求めた。
専門パネラー3名による皮膚刺激感強度の評価を行った。実施例及び比較例の水蒸気発生温熱具及び乾熱の温熱具を肩部に3時間適用した際の皮膚刺激感強度を、「0:感じない」「1:弱く感じる、弱すぎる」「2:やや弱く感じる」「3:ちょうどよく感じる」「4:やや強く感じる」「5:強く感じる、強すぎる」の6段階で評価し、平均値を求めた。
両肩部に痛みを訴える対象者10名に対し、片方の肩に当該温熱具を3時間適用し、当該温熱具を適用していないもう一方の肩(非適用肩)の痛みレベルの適用前後での変化を、知覚・痛覚定量分析装置(Pain Vision PS-2100、(株)オサチ社製)を用いて下記1)~5)の手順にて評価し、結果を図3に示した。
1)知覚閾値測定
まず、あらかじめ対象者の知覚閾値を測定した。左前腕内側に、2つの電極パッドを2cm離して取り付け電流を流した。電流値を徐々に高めていき、対象者が左前腕内側に何らかの皮膚感覚を感じた時点で申告させ、そのときの電流値を「電流知覚閾値」とした。
2)非適用肩痛み度(適用前)算出
次に、蒸気発生温熱具適用前の対象者の肩の痛みのレベルを測定した。肩の痛みは、「肩を押す」「肩を回す」などの外部刺激により生じるため、プッシュプルゲージ(アイコーエンジニアリング(株)社製)にて肩部において対象者が痛みを訴えるポイントを一定圧力(4.5kg/15mmφ)で加圧し痛みを発生させた上で、左前腕内側に、1)と同様に2つの電極パットを2cm離して取り付け電流を流し、電流値を徐々に高めていき、電流による刺激が肩の痛みと同程度になった時点で申告させ、そのときの電流値を「非適用肩痛み対応電流値(適用前)」とした。そして下記式(1)に従って痛み度を算出し、この値を「非適用肩痛み度(適用前)」とした。
非適用肩痛み度(適用前)=〔(非適用肩痛み対応電流値(適用前)-電流知覚閾値)/電流知覚閾値〕×100 ・・・(1)
3)右前腕部痛み度(適用前)算出
更に、右前腕部をプッシュプルゲージ(アイコーエンジニアリング(株)社製)にて一定圧力(4.5kg/15mmφ)で加圧し痛みを発生させた上で、左前腕内側に、1)と同様に2つの電極パットを2cm離して取り付け電流を流し、電流値を徐々に高めていき、電流による刺激が右前腕部の痛みと同程度になった時点で申告させ、そのときの電流値を「右前腕部痛み対応電流値(適用前)」とした。そして下記式(2)に従って痛み度を算出し、この値を「右前腕部痛み度(適用前)」とした。
右前腕部痛み度(適用前)=〔(右前腕部痛み対応電流値(適用前)-電流知覚閾値)/電流知覚閾値〕×100 ・・・(2)
4)非適用肩相対痛み度(適用前)算出
これら2)及び3)より得られた「非適用肩痛み度(適用前)」及び「右前腕部痛み度(適用前)」より、下記式(3)に従って非適用肩相対痛み度(適用前)を算出した。
非適用肩相対痛み度(適用前)=(非適用肩痛み度(適用前)/右前腕部痛み度(適用前))×100・・・(3)
5)非適用肩相対痛み度(適用後)算出
片方の肩に当該温熱具を3時間適用した後、2)~4)と同様の操作を行って当該温熱具を適用していないもう一方の肩(非適用肩)の「非適用肩痛み度(適用後)」及び「右前腕部痛み度(適用後)」を測定し、非適用肩相対痛み度(適用後)を算出した。
両肩部に痛みを訴える対象者10名に対し、片方の肩に当該温熱具を3時間適用し、蒸気発生温熱具を適用していないもう片方の肩(非適用肩)の皮膚温度(3分間の平均値)の適用前後での変化を、温度ロガー(LT-8、グラム(株)社製)を用いて評価し、結果を図4に示した。
Claims (11)
- 被酸化性金属の酸化による発熱に伴って水蒸気を放出する水蒸気発生部を有する水蒸気発生温熱具であって、
カプサイシン類縁体及びメントール類を含有し、
カプサイシン類縁体とメントール類との質量比(カプサイシン類縁体/メントール類)を1/300~1/20000とした水蒸気発生温熱具。 - カプサイシン類縁体を水蒸気発生温熱具の部材のうち、使用者の肌に直接接する部材に存在させ、かつメントール類を水蒸気発生温熱具の部材のうち、使用者の肌に触れない部材に存在させる請求項1記載の水蒸気発生温熱具。
- 包材と該包材内に密封収容された水蒸気発生部とを備えており、
前記包材が使用時に使用者の肌側を向く肌対向面と、外側を向く外面とを有し、
肌対向面が身体側シートから構成されており、該身体側シートにカプサイシン類縁体が保持されており、
身体側シートに保持させるカプサイシン類縁体の量が、カプサイシン類縁体を施した部位の面積に基づき0.05~5.0μg/cm2である請求項1又は2記載の水蒸気発生温熱具。 - 水蒸気発生部中にメントール類が存在している請求項1ないし3のいずれか一項に記載の水蒸気発生温熱具。
- 単位面積あたり60分間に発生する水蒸気量が、5~50mg/(cm2・60min)である請求項1ないし4のいずれか一項に記載の水蒸気発生温熱具。
- 身体側シートの少なくとも一部が不織布からなる請求項3ないし5のいずれか一項に記載の水蒸気発生温熱具。
- カプサイシン類縁体が、一般式(1)で表されるものである請求項1ないし6のいずれか一項に記載の水蒸気発生温熱具。
- メントール類が、l-メントール及び/又はdl-メントールである請求項1ないし7のいずれか一項に記載の水蒸気発生温熱具。
- 水蒸気発生部の面積が、平面視で1.0~30cm2である請求項1ないし8のいずれか一項に記載の水蒸気発生温熱具。
- 水蒸気発生部が、少なくとも一部に透気性を有するシートによって被覆されており、該シートは水蒸気発生温熱具の使用時に使用者の肌側を向く第1のシートと、使用時に外側を向く第2のシートとを有しており、第1のシートの透気度よりも第2のシートの透気度が大きい請求項1ないし9のいずれか一項に記載の水蒸気発生温熱具。
- 使用者の肌に直接当接された状態において肌表面温度を1~5時間にわたり38~43℃に維持させるような発熱特性を有している請求項1ないし10のいずれか一項に記載の水蒸気発生温熱具。
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US13/702,207 US9931241B2 (en) | 2010-06-09 | 2011-06-08 | Steam-generative warming device |
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US9931241B2 (en) | 2018-04-03 |
KR20130080429A (ko) | 2013-07-12 |
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EP2581065A1 (en) | 2013-04-17 |
CN102869326B (zh) | 2017-04-05 |
CN102869326A (zh) | 2013-01-09 |
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US20130079851A1 (en) | 2013-03-28 |
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