UA78275C2 - Oxa- and thiadiasols and their use as inhibitors of matrix metalloproteinases - Google Patents
Oxa- and thiadiasols and their use as inhibitors of matrix metalloproteinases Download PDFInfo
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- UA78275C2 UA78275C2 UA20040806941A UA20040806941A UA78275C2 UA 78275 C2 UA78275 C2 UA 78275C2 UA 20040806941 A UA20040806941 A UA 20040806941A UA 20040806941 A UA20040806941 A UA 20040806941A UA 78275 C2 UA78275 C2 UA 78275C2
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- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- C07—ORGANIC CHEMISTRY
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
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- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
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- Vascular Medicine (AREA)
- Hematology (AREA)
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- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0204159.8A GB0204159D0 (en) | 2002-02-22 | 2002-02-22 | Metalloproteinase inhibitors |
| PCT/GB2003/000741 WO2003070711A1 (en) | 2002-02-22 | 2003-02-20 | Oxa- and thiadiazoles and their use as metalloproteinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA78275C2 true UA78275C2 (en) | 2007-03-15 |
Family
ID=9931543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20040806941A UA78275C2 (en) | 2002-02-22 | 2003-02-20 | Oxa- and thiadiasols and their use as inhibitors of matrix metalloproteinases |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US7358265B2 (de) |
| EP (1) | EP1476438B1 (de) |
| JP (1) | JP4615864B2 (de) |
| KR (1) | KR101098614B1 (de) |
| CN (1) | CN100351245C (de) |
| AT (1) | ATE360007T1 (de) |
| AU (1) | AU2003205910B2 (de) |
| BR (1) | BR0307899A (de) |
| CA (1) | CA2475867C (de) |
| CY (1) | CY1106730T1 (de) |
| DE (1) | DE60313292T2 (de) |
| DK (1) | DK1476438T3 (de) |
| EA (1) | EA007609B1 (de) |
| ES (1) | ES2286404T3 (de) |
| GB (1) | GB0204159D0 (de) |
| HK (1) | HK1078583A1 (de) |
| HR (1) | HRP20040725A2 (de) |
| IL (1) | IL163413A (de) |
| MX (1) | MXPA04008132A (de) |
| NO (1) | NO330772B1 (de) |
| PL (1) | PL210773B1 (de) |
| PT (1) | PT1476438E (de) |
| RS (1) | RS51354B (de) |
| SI (1) | SI1476438T1 (de) |
| UA (1) | UA78275C2 (de) |
| WO (1) | WO2003070711A1 (de) |
| ZA (1) | ZA200406755B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2003227952A1 (en) * | 2003-05-17 | 2004-12-03 | British Biotech Pharmaceuticals Ltd | Metalloproteinase inhibitors |
| US7786121B2 (en) * | 2003-08-23 | 2010-08-31 | Vernalis (Oxford) Limited | Derivatives of hydroxamic acid as metalloproteinase inhibitors |
| US7838522B2 (en) | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
| BRPI0516383A (pt) | 2004-12-21 | 2008-09-02 | Serono Lab | derivados cìclicos de sulfonil amino e o uso dos mesmos |
| WO2006079653A1 (en) | 2005-01-31 | 2006-08-03 | Laboratoires Serono S.A. | N-hydroxyamide derivatives and use thereof |
| BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 ｊｎｋ 억제제 |
| EA013816B1 (ru) | 2005-09-01 | 2010-08-30 | Арес Трейдинг С.А. | Лечение неврита зрительного нерва |
| US8153166B2 (en) * | 2006-06-08 | 2012-04-10 | Chih-Hsiung Lin | Composition for prophylaxis or treatment of urinary system infection and method thereof |
| CA2922607C (en) | 2013-09-06 | 2022-08-30 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole derivatives as immunomodulators |
| WO2016142833A1 (en) | 2015-03-10 | 2016-09-15 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| CA2979161A1 (en) * | 2015-03-10 | 2016-09-15 | Aurigene Discovery Technologies Limited | 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| CN105384736B (zh) * | 2015-10-28 | 2018-11-02 | 南昌大学 | 一种ⅳ型胶原酶抑制剂及合成方法 |
| WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
| EP3694841A1 (de) | 2017-10-11 | 2020-08-19 | Aurigene Discovery Technologies Limited | Kristalline formen von 3-substituiertem 1,2,4-oxadiazol |
| JP7378394B2 (ja) | 2017-11-03 | 2023-11-13 | オーリジーン オンコロジー リミテッド | Ｔｉｍ－３およびｐｄ－１経路の二重阻害剤 |
| EA202090749A1 (ru) | 2017-11-06 | 2020-08-19 | Ориджен Дискавери Текнолоджис Лимитед | Способы совместной терапии для иммуномодуляции |
| CN108530378B (zh) * | 2018-05-29 | 2021-09-14 | 济南大学 | 一类含有噁二唑结构的氮原子双取代异羟肟酸类化合物、用途及其制备方法 |
Family Cites Families (8)
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| US5665753A (en) * | 1994-03-03 | 1997-09-09 | Smithkline Beecham Corporation | Cytokine inhibiting imidazole substituted hydroxamic acid derivatives |
| GB9404046D0 (en) * | 1994-03-03 | 1994-04-20 | Smithkline Beecham Corp | Novel compounds |
| US5703092A (en) * | 1995-04-18 | 1997-12-30 | The Dupont Merck Pharmaceutical Company | Hydroxamic acid compounds as metalloprotease and TNF inhibitors |
| JP2001507342A (ja) * | 1996-12-17 | 2001-06-05 | ワーナー−ランバート・コンパニー | 神経疾患の治療および創傷治癒を促進するためのマトリックスメタロプロテイナーゼ阻害剤の使用 |
| EP1064289A1 (de) * | 1998-03-18 | 2001-01-03 | Ariad Pharmaceuticals, Inc. | Heterozyclische inhibitoren von signal-transduction, sie enthaltende zusammensetzungen |
| JP2001031637A (ja) * | 1999-05-17 | 2001-02-06 | Fuji Chemical Industries Ltd | 新規なヒドロキサム酸誘導体 |
| US6448278B2 (en) * | 1999-12-23 | 2002-09-10 | Pfizer Inc. | Procollagen C-proteinase inhibitors |
| GB9930570D0 (en) * | 1999-12-23 | 2000-02-16 | Pfizer Ltd | Therapy |
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2002
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2004
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2006
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2007
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2010
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