UA75425C2 - Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds - Google Patents
Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds Download PDFInfo
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- UA75425C2 UA75425C2 UA2004020930A UA2004020930A UA75425C2 UA 75425 C2 UA75425 C2 UA 75425C2 UA 2004020930 A UA2004020930 A UA 2004020930A UA 2004020930 A UA2004020930 A UA 2004020930A UA 75425 C2 UA75425 C2 UA 75425C2
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- ylmethyl
- disorders
- indol
- compounds
- bis
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202631 | 2001-07-09 | ||
| PCT/EP2002/007472 WO2003006459A1 (en) | 2001-07-09 | 2002-07-03 | Piperazine oxime derivatives having nk-1 receptor antagonistic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA75425C2 true UA75425C2 (en) | 2006-04-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| UA2004020930A UA75425C2 (en) | 2001-07-09 | 2002-03-07 | Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds |
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| Country | Link |
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| US (1) | US7094779B2 (pt) |
| EP (1) | EP1406894B1 (pt) |
| JP (1) | JP3765543B2 (pt) |
| KR (1) | KR100900889B1 (pt) |
| CN (1) | CN1223591C (pt) |
| AR (1) | AR034722A1 (pt) |
| AT (1) | ATE285407T1 (pt) |
| AU (1) | AU2002333229B2 (pt) |
| BR (1) | BR0210080A (pt) |
| CA (1) | CA2446726A1 (pt) |
| DE (1) | DE60202371T2 (pt) |
| DK (1) | DK1406894T3 (pt) |
| ES (1) | ES2230521T3 (pt) |
| HK (1) | HK1067364A1 (pt) |
| HR (1) | HRP20030912A2 (pt) |
| HU (1) | HUP0401093A3 (pt) |
| IL (2) | IL158728A0 (pt) |
| MX (1) | MXPA04000230A (pt) |
| NO (1) | NO20040065L (pt) |
| PL (1) | PL366841A1 (pt) |
| PT (1) | PT1406894E (pt) |
| RU (1) | RU2273639C2 (pt) |
| SI (1) | SI1406894T1 (pt) |
| UA (1) | UA75425C2 (pt) |
| WO (1) | WO2003006459A1 (pt) |
| ZA (1) | ZA200308782B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DK1696920T3 (en) | 2003-12-19 | 2015-01-19 | Plexxikon Inc | RELATIONS AND PROCEDURES FOR THE DEVELOPMENT OF LAW MODULATORS |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| KR100616099B1 (ko) * | 2004-09-20 | 2006-08-28 | 한국과학기술연구원 | Ｔ-타입 칼슘채널 길항제로 유효한 신규 피페라지닐알킬이소옥사졸 유도체 |
| WO2007013896A2 (en) | 2005-05-17 | 2007-02-01 | Plexxikon, Inc. | Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors |
| DK1893612T3 (da) | 2005-06-22 | 2011-11-21 | Plexxikon Inc | Pyrrol [2,3-B]pyridin-derivater som proteinkinasehæmmere |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| WO2008104942A2 (en) * | 2007-02-28 | 2008-09-04 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| WO2009012283A1 (en) | 2007-07-17 | 2009-01-22 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| ES2552386T3 (es) | 2009-04-03 | 2015-11-27 | F. Hoffmann-La Roche Ag | Composiciones de {3-[5-(4-cloro-fenil)-1H-pirrol[2,3-b]piridin-3-carbonil]-2,4-difluoro-fenil}-amida del ácido propano-1-sulfónico y usos de las mismas |
| JP2013510166A (ja) | 2009-11-06 | 2013-03-21 | プレキシコン インコーポレーテッド | キナーゼ調節のための化合物、方法およびその適用 |
| AU2012214762B2 (en) | 2011-02-07 | 2015-08-13 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
| TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| CN104958297A (zh) * | 2015-06-03 | 2015-10-07 | 周玉梅 | 一种用于麻醉镇静催眠的药物组合物及其应用 |
| CN110615774B (zh) * | 2019-09-19 | 2022-11-11 | 安徽中医药大学 | 具有抗炎活性的苄基哌嗪类化合物、制法及医药用途 |
| JP2022090346A (ja) | 2020-12-07 | 2022-06-17 | 三星電子株式会社 | 共重合体、ならびに当該共重合体を用いるエレクトロルミネッセンス素子材料およびエレクトロルミネッセンス素子 |
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| IL111730A (en) | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
| KR19990008230A (ko) | 1995-05-02 | 1999-01-25 | 덜락 노만씨 | 뉴로키닌 길항제로서의 피페라지노 유도체 |
| US5696267A (en) * | 1995-05-02 | 1997-12-09 | Schering Corporation | Substituted oximes, hydrazones and olefins as neurokinin antagonists |
| KR19990021857A (ko) * | 1995-05-25 | 1999-03-25 | 후지야마 아키라 | 뉴로키닌 수용체 길항물질로서 1-벤조일-2-(인돌일-3-알킬)-피페라진 유도체 |
| CA2240835A1 (en) * | 1995-12-18 | 1997-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives as tachykinin antagonists |
| JP4189043B2 (ja) | 1996-09-30 | 2008-12-03 | 株式会社資生堂 | Ｎ−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
| AUPO735997A0 (en) * | 1997-06-17 | 1997-07-10 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
| DE19824865A1 (de) * | 1997-08-27 | 1999-03-04 | Solvay Pharm Gmbh | Neue Harnstoffderivate |
| ATE396187T1 (de) | 1997-08-27 | 2008-06-15 | Solvay Pharm Gmbh | Indolmethyl-n,n'-bisacylpiperazine als neurokininrezeptorantagonisten |
| DE69920516T2 (de) | 1998-12-23 | 2005-12-01 | Schering Corp. | Substituierte oxime und hydrazone als neurokinin antagonisten |
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- 2002-07-03 HU HU0401093A patent/HUP0401093A3/hu unknown
- 2002-07-03 US US10/480,542 patent/US7094779B2/en not_active Expired - Fee Related
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- 2002-07-03 ES ES02784838T patent/ES2230521T3/es not_active Expired - Lifetime
- 2002-07-03 CA CA002446726A patent/CA2446726A1/en not_active Abandoned
- 2002-07-03 JP JP2003512231A patent/JP3765543B2/ja not_active Expired - Fee Related
- 2002-07-03 WO PCT/EP2002/007472 patent/WO2003006459A1/en active IP Right Grant
- 2002-07-03 AT AT02784838T patent/ATE285407T1/de not_active IP Right Cessation
- 2002-07-03 PT PT02784838T patent/PT1406894E/pt unknown
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2003
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2004
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- 2004-12-14 HK HK04109874A patent/HK1067364A1/xx not_active IP Right Cessation
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