UA68383C2 - Phthalazine derivatives and pharmaceutical compositions - Google Patents

Phthalazine derivatives and pharmaceutical compositions Download PDF

Info

Publication number
UA68383C2
UA68383C2 UA2001010439A UA2001010439A UA68383C2 UA 68383 C2 UA68383 C2 UA 68383C2 UA 2001010439 A UA2001010439 A UA 2001010439A UA 2001010439 A UA2001010439 A UA 2001010439A UA 68383 C2 UA68383 C2 UA 68383C2
Authority
UA
Ukraine
Prior art keywords
methoxy
mmol
compound
methyl
dichloropyridin
Prior art date
Application number
UA2001010439A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of UA68383C2 publication Critical patent/UA68383C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
UA2001010439A 1998-07-21 1999-07-13 Phthalazine derivatives and pharmaceutical compositions UA68383C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT98MI001670A ITMI981670A1 (it) 1998-07-21 1998-07-21 Derivati ftalazinici inibitori della fosfodiesterasi 4
PCT/EP1999/004904 WO2000005218A1 (en) 1998-07-21 1999-07-13 Phthalazine derivatives phosphodiesterase 4 inhibitors

Publications (1)

Publication Number Publication Date
UA68383C2 true UA68383C2 (en) 2004-08-16

Family

ID=11380474

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2001010439A UA68383C2 (en) 1998-07-21 1999-07-13 Phthalazine derivatives and pharmaceutical compositions

Country Status (35)

Country Link
US (2) US6329370B1 (xx)
EP (2) EP1097142B1 (xx)
JP (1) JP2002521370A (xx)
KR (1) KR20010087161A (xx)
CN (1) CN1127486C (xx)
AP (1) AP2000001993A0 (xx)
AR (1) AR019409A1 (xx)
AT (1) ATE279397T1 (xx)
AU (1) AU765457B2 (xx)
BG (1) BG105063A (xx)
BR (1) BR9911175A (xx)
CA (1) CA2338044A1 (xx)
CO (1) CO5090842A1 (xx)
DE (1) DE69921139T2 (xx)
EA (1) EA200100062A1 (xx)
EE (1) EE200100039A (xx)
HK (1) HK1039124B (xx)
HR (1) HRP20010057A2 (xx)
HU (1) HUP0102646A3 (xx)
ID (1) ID28874A (xx)
IL (1) IL139490A0 (xx)
IS (1) IS5772A (xx)
IT (1) ITMI981670A1 (xx)
MX (1) MXPA01000670A (xx)
NO (1) NO318988B1 (xx)
NZ (1) NZ507926A (xx)
OA (1) OA11582A (xx)
PA (1) PA8478301A1 (xx)
PE (1) PE20000755A1 (xx)
PL (1) PL345187A1 (xx)
SK (1) SK1002001A3 (xx)
TW (1) TW509682B (xx)
UA (1) UA68383C2 (xx)
WO (1) WO2000005218A1 (xx)
YU (1) YU77500A (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4
ITMI981671A1 (it) 1998-07-21 2000-01-21 Zambon Spa Derivati ftalazinici inibitori della fosfodisterasi 4
DE19921567A1 (de) 1999-05-11 2000-11-16 Basf Ag Verwendung von Phthalazine-Derivaten
DE19963607B4 (de) * 1999-12-23 2005-12-15 Schering Ag Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
ITMI20000261A1 (it) 2000-02-16 2001-08-16 Zambon Group Processo per la preparazione di piridiniliden-ftalidi
US6703390B2 (en) * 2000-04-13 2004-03-09 Transgenomic, Inc. Sulfur containing dihydrophthalazine antagonists of excitatory amino acid receptors
US6525049B2 (en) * 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
AU2002220241A1 (en) * 2000-12-01 2002-06-11 Iconix Pharmaceuticals, Inc. Parb inhibitors
ITMI20022738A1 (it) * 2002-12-23 2004-06-24 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4.
ITMI20022739A1 (it) * 2002-12-23 2004-06-24 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4.
WO2004076386A2 (en) 2003-02-25 2004-09-10 Topotarget Uk Limited Carbamic acid compounds comprising a bicyclic heteroaryl group as hdac inhibitors
ITMI20031451A1 (it) * 2003-07-16 2005-01-17 Zambon Spa Derivati diidro-ftalazinici inibitori della fosfodiesterasi 4
WO2006004589A2 (en) * 2004-05-08 2006-01-12 Neurogen Corporation 3-aryl-5,6-disubstituted pyridazines
EP1833803A4 (en) * 2005-01-03 2009-08-05 Myriad Genetics Inc PHARMACEUTICAL COMPOUNDS COMPRISING CASPASE ACTIVATORS AND INDUCERS OF APOPTOSIS AND THE USE THEREOF
AU2006305619A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
CA2669687C (en) 2006-11-15 2013-09-10 Forest Laboratories Holdings Limited Phthalazine derivatives
US8969348B2 (en) * 2008-08-13 2015-03-03 Boehringer Ingelheim International Gmbh Chymase inhibitors
CN102108078B (zh) * 2009-12-24 2013-10-30 沈阳药科大学 1,4-取代酞嗪类化合物及其制备方法和用途
RU2014123352A (ru) * 2011-11-09 2015-12-20 Эббви Дойчланд Гмбх Унд Ко. Кг Гетероциклические карбоксамиды, полезные в качестве ингибиторов фосфодиэстеразы типа 10а

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2063249A (en) * 1979-10-09 1981-06-03 Mitsubishi Yuka Pharma 4-Phenylphthalazine derivatives
JPH03106873A (ja) * 1989-09-20 1991-05-07 Morishita Pharmaceut Co Ltd １―ピリジルフタラジン誘導体及びそれらを含有する血小板凝集抑制剤
ES2068413T3 (es) * 1990-03-30 1995-04-16 Mitsubishi Chem Ind Derivados de 4-fenilftalazina.
EP0634404A1 (en) * 1993-07-13 1995-01-18 Rhone Poulenc Agriculture Ltd. Phtalazin derivatives and their use as pesticides
EP0722936B1 (en) * 1994-08-09 2004-05-19 Eisai Co., Ltd. Fused pyridazine compound
IT1296984B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati ftalazinici inibitori della fosfodiesterasi 4

Also Published As

Publication number Publication date
JP2002521370A (ja) 2002-07-16
IL139490A0 (en) 2001-11-25
ATE279397T1 (de) 2004-10-15
BR9911175A (pt) 2001-03-20
AP2000001993A0 (en) 2000-12-31
DE69921139D1 (de) 2004-11-18
WO2000005218A1 (en) 2000-02-03
NO20010331L (no) 2001-03-20
AU765457B2 (en) 2003-09-18
SK1002001A3 (en) 2001-12-03
CN1127486C (zh) 2003-11-12
EP1097142B1 (en) 2004-10-13
EE200100039A (et) 2002-06-17
NZ507926A (en) 2002-10-25
TW509682B (en) 2002-11-11
KR20010087161A (ko) 2001-09-15
AU5281099A (en) 2000-02-14
HRP20010057A2 (en) 2002-04-30
PL345187A1 (en) 2001-12-03
EP1371648A1 (en) 2003-12-17
DE69921139T2 (de) 2005-10-13
HK1039124B (zh) 2005-04-01
US6329370B1 (en) 2001-12-11
ID28874A (id) 2001-07-12
AR019409A1 (es) 2002-02-20
BG105063A (en) 2001-07-31
MXPA01000670A (es) 2002-05-14
HK1039124A1 (en) 2002-04-12
EA200100062A1 (ru) 2001-08-27
CN1305467A (zh) 2001-07-25
EP1097142A1 (en) 2001-05-09
IS5772A (is) 2000-12-15
CO5090842A1 (es) 2001-10-30
YU77500A (sh) 2002-11-15
CA2338044A1 (en) 2000-02-03
NO318988B1 (no) 2005-05-30
US6492360B1 (en) 2002-12-10
HUP0102646A3 (en) 2003-01-28
PE20000755A1 (es) 2000-09-01
HUP0102646A2 (hu) 2001-12-28
OA11582A (en) 2004-07-26
ITMI981670A1 (it) 2000-01-21
PA8478301A1 (es) 2000-09-29
NO20010331D0 (no) 2001-01-19
ITMI981670A0 (it) 1998-07-21

Similar Documents

Publication Publication Date Title
UA68383C2 (en) Phthalazine derivatives and pharmaceutical compositions
US5231101A (en) Benzo[5,6]cyclohepta[1,2-B]pyridine derivatives and antiallergic agents comprising same
WO2006038734A1 (en) Pyridazinone derivatives cytokines inhibitors
AU2006218125A1 (en) Pyrrolidine and piperidine acetylene derivatives for use as mGluR5 antagonists
HRP20050199A2 (hr) Novi derivati piridazinona
CN101490040A (zh) 用于治疗对嗜中性白细胞弹性蛋白酶活性的抑制是有益的疾病或病症的2-吡嗪酮衍生物
EP2124565A2 (en) N-substituted glycine derivatives: hydroxylase inhibitors
EA018385B1 (ru) АМИДОФЕНОКСИИНДАЗОЛЫ В КАЧЕСТВЕ ИНГИБИТОРОВ c-Met
JP2007519692A (ja) ｐ３８キナーゼ阻害剤として使用するための縮合ヘテロアリール誘導体
CN101490033A (zh) 用于治疗对嗜中性白细胞弹性蛋白酶活性的抑制是有益的疾病或病症的2-吡啶酮衍生物
JP2013506649A (ja) 好中球エラスターゼの阻害剤として使用する２−ピリドン化合物
RU2649002C2 (ru) Производные бензимидазол-2-пиперазина, полезные в качестве ингибитора поли(АДФ-рибоза)-полимеразы (PARP)
TW200829247A (en) 2-phenyl-6-aminocarbonyl-pyrimidine derivatives
WO2007114763A1 (en) Sulphonamide derivates as modulators of the glucocorticoid receptor
WO2018228475A1 (zh) Syk抑制剂及其使用方法
JPH06211839A (ja) 抗ウイルス剤としてのフェノキシ及びフェノキシアルキルピペリジン類
KR20090031605A (ko) 신규한 피리딘 유사체
AU2014253810A1 (en) Substituted condensed pyrimidine compounds
US6358973B1 (en) Benzazine derivatives as phosphodiesterase 4 inhibitors
KR101586714B1 (ko) 피라졸 화합물
WO2002092593A1 (en) 4-(4-pyridazinyl)pyrazole derivatives
TW200404063A (en) Novel alkansulfonamides
TW202342458A (zh) Ｐａｒｇ抑制劑
CN102245593A (zh) 异喹啉酮衍生物
CZ2001241A3 (cs) Ftalazinové deriváty