UA66339C2 - Зрізаний нейротрофічний фактор, що походить з лінії гліальних клітин (gdnf), молекула днк, яка кодує gdnf, вектор, що містить зазначену молекулу днк, клітина-хазяїн, спосіб виготовлення зрізаного gdnf, фармацевтична композиція та спосіб лікування - Google Patents

Зрізаний нейротрофічний фактор, що походить з лінії гліальних клітин (gdnf), молекула днк, яка кодує gdnf, вектор, що містить зазначену молекулу днк, клітина-хазяїн, спосіб виготовлення зрізаного gdnf, фармацевтична композиція та спосіб лікування Download PDF

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Publication number
UA66339C2
UA66339C2 UA98031545A UA98031545A UA66339C2 UA 66339 C2 UA66339 C2 UA 66339C2 UA 98031545 A UA98031545 A UA 98031545A UA 98031545 A UA98031545 A UA 98031545A UA 66339 C2 UA66339 C2 UA 66339C2
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UA
Ukraine
Prior art keywords
truncated
protein
sequence
zeo
zome
Prior art date
Application number
UA98031545A
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English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Шоу-Фен Ху
Original Assignee
Амген Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Амген Інк. filed Critical Амген Інк.
Publication of UA66339C2 publication Critical patent/UA66339C2/uk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
UA98031545A 1995-09-28 1996-09-16 Зрізаний нейротрофічний фактор, що походить з лінії гліальних клітин (gdnf), молекула днк, яка кодує gdnf, вектор, що містить зазначену молекулу днк, клітина-хазяїн, спосіб виготовлення зрізаного gdnf, фармацевтична композиція та спосіб лікування UA66339C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/535,681 US6184200B1 (en) 1995-09-28 1995-09-28 Truncated glial cell line-derived neurotrophic factor
PCT/US1996/014915 WO1997011964A1 (en) 1995-09-28 1996-09-16 Truncated glial cell line-derived neurotrophic factor

Publications (1)

Publication Number Publication Date
UA66339C2 true UA66339C2 (uk) 2004-05-17

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
UA98031545A UA66339C2 (uk) 1995-09-28 1996-09-16 Зрізаний нейротрофічний фактор, що походить з лінії гліальних клітин (gdnf), молекула днк, яка кодує gdnf, вектор, що містить зазначену молекулу днк, клітина-хазяїн, спосіб виготовлення зрізаного gdnf, фармацевтична композиція та спосіб лікування

Country Status (25)

Country Link
US (5) US6184200B1 (cs)
EP (1) EP0920448B1 (cs)
JP (3) JP4153036B2 (cs)
KR (1) KR100334739B1 (cs)
CN (1) CN1283659C (cs)
AT (1) ATE314389T1 (cs)
AU (1) AU707528B2 (cs)
CA (1) CA2232749C (cs)
CZ (1) CZ297326B6 (cs)
DE (1) DE69635675T2 (cs)
DK (1) DK0920448T3 (cs)
EA (1) EA001204B1 (cs)
ES (1) ES2255713T3 (cs)
HK (1) HK1021823A1 (cs)
HU (1) HU226220B1 (cs)
IL (6) IL144488A0 (cs)
MX (1) MX9802278A (cs)
NO (1) NO322521B1 (cs)
NZ (1) NZ318697A (cs)
SI (1) SI0920448T1 (cs)
SK (1) SK288094B6 (cs)
TW (1) TW570926B (cs)
UA (1) UA66339C2 (cs)
WO (1) WO1997011964A1 (cs)
ZA (1) ZA968087B (cs)

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US20020055467A1 (en) * 1998-07-06 2002-05-09 Johansen Teit E. Novel neurotrophic factors
US6507788B1 (en) * 1999-02-25 2003-01-14 Société de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.) Rational selection of putative peptides from identified nucleotide, or peptide sequences, of unknown function
US6897061B1 (en) * 2000-06-16 2005-05-24 Spinal Cord Society Transdifferentiation of glial cells
US7442370B2 (en) 2001-02-01 2008-10-28 Biogen Idec Ma Inc. Polymer conjugates of mutated neublastin
US7276580B2 (en) 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
US8946151B2 (en) 2003-02-24 2015-02-03 Northern Bristol N.H.S. Trust Frenchay Hospital Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
US7245117B1 (en) 2004-11-01 2007-07-17 Cardiomems, Inc. Communicating with implanted wireless sensor
US20060239966A1 (en) * 2003-10-20 2006-10-26 Tornoee Jens In vivo gene therapy of parkinson's disease
JP2007509109A (ja) 2003-10-20 2007-04-12 エヌエスジーン・アクティーゼルスカブ パーキンソン病のインビボ遺伝子治療
AU2005277227B2 (en) 2004-08-19 2011-10-06 Biogen Ma Inc. Refolding transforming growth factor beta family proteins
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
EP2054074B8 (en) * 2006-08-04 2014-11-12 Prolong Pharmaceuticals, LLC Modified erythropoietin
WO2008100966A1 (en) * 2007-02-12 2008-08-21 The Research Foundation Of State University Of New York Gdnf-derived peptides
JP5583005B2 (ja) 2007-05-01 2014-09-03 バイオジェン・アイデック・エムエイ・インコーポレイテッド 血管新生を増大させるための組成物および方法
US8446454B2 (en) * 2007-05-21 2013-05-21 Polycom, Inc. Dynamic adaption of a continuous presence videoconferencing layout based on video content
FI20070808A0 (fi) 2007-10-25 2007-10-25 Mart Saarma GDNF:n silmukointivariantit ja niiden käytöt
UA112981C2 (uk) 2011-04-11 2016-11-25 Елі Ліллі Енд Компані Варіант людського gdnf
US10376562B2 (en) 2013-03-15 2019-08-13 The Jackson Laboratory Methods for promoting wound healing and hair growth comprising GDNF administration
RU2561050C2 (ru) 2013-08-28 2015-08-20 Федеральное государственное бюджетное учреждение науки Институт биофизики клетки Российской академии наук (ИБК РАН) Применение белка yb-1 и его фрагментов для изготовления лекарственных средств при лечении болезни альцгеймера
AU2017357931A1 (en) 2016-11-10 2019-06-20 Keros Therapeutics, Inc. GDNF fusion polypeptides and methods of use thereof
JP2023515915A (ja) * 2019-12-19 2023-04-17 トランスフェルト・プラス・ソシエテ・アン・コマンディテ 腸のニューロパチーを治療するためのグリア細胞株由来神経栄養因子(gdnf)の使用
TW202325850A (zh) 2021-11-29 2023-07-01 大陸商上海瑞宏迪醫藥有限公司 Aadc、gdnf多核苷酸及其用於治療帕金森病

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Also Published As

Publication number Publication date
EP0920448B1 (en) 2005-12-28
KR100334739B1 (ko) 2002-09-17
IL144018A0 (en) 2002-04-21
HUP9802262A2 (hu) 1999-01-28
JP2010279360A (ja) 2010-12-16
KR19990063825A (ko) 1999-07-26
NZ318697A (en) 1999-09-29
CA2232749C (en) 2003-03-25
ZA968087B (en) 1997-06-12
IL123761A0 (en) 1998-10-30
SI0920448T1 (sl) 2006-04-30
JP2008067699A (ja) 2008-03-27
SK288094B6 (sk) 2013-07-02
TW570926B (en) 2004-01-11
US7611865B2 (en) 2009-11-03
CZ88298A3 (cs) 1999-02-17
NO322521B1 (no) 2006-10-16
IL144018A (en) 2012-04-30
IL144488A (en) 2006-12-31
AU7074696A (en) 1997-04-17
EA001204B1 (ru) 2000-12-25
MX9802278A (es) 1998-08-30
US7390781B2 (en) 2008-06-24
HU226220B1 (hu) 2008-06-30
CA2232749A1 (en) 1997-04-03
ES2255713T3 (es) 2006-07-01
IL144488A0 (en) 2002-05-23
NO981430L (no) 1998-03-30
US20040127419A1 (en) 2004-07-01
US20040214776A1 (en) 2004-10-28
ATE314389T1 (de) 2006-01-15
JPH11512709A (ja) 1999-11-02
EA199800301A1 (ru) 1998-10-29
CN1283659C (zh) 2006-11-08
EP0920448A1 (en) 1999-06-09
JP5241037B2 (ja) 2013-07-17
DE69635675T2 (de) 2006-07-06
JP4909843B2 (ja) 2012-04-04
SK38998A3 (en) 1999-07-12
US6184200B1 (en) 2001-02-06
DE69635675D1 (de) 2006-02-02
DK0920448T3 (da) 2006-04-10
HK1021823A1 (en) 2000-07-07
CN1197461A (zh) 1998-10-28
WO1997011964A1 (en) 1997-04-03
CZ297326B6 (cs) 2006-11-15
HUP9802262A3 (en) 2001-01-29
IL123761A (en) 2005-12-18
AU707528B2 (en) 1999-07-15
US20040254114A1 (en) 2004-12-16
JP4153036B2 (ja) 2008-09-17
IL218336A0 (en) 2012-04-30
NO981430D0 (no) 1998-03-30
US20110251267A1 (en) 2011-10-13

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