UA32546C2 - 1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом - Google Patents

1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом

Info

Publication number
UA32546C2
UA32546C2 UA94020490A UA94020490A UA32546C2 UA 32546 C2 UA32546 C2 UA 32546C2 UA 94020490 A UA94020490 A UA 94020490A UA 94020490 A UA94020490 A UA 94020490A UA 32546 C2 UA32546 C2 UA 32546C2
Authority
UA
Ukraine
Prior art keywords
mammals
imidazo
quinoline
amines
substituted
Prior art date
Application number
UA94020490A
Other languages
English (en)
Russian (ru)
Inventor
Джон Ф. Герстер
Штефен Л. Крукс
Кайл Дж. Ліндстром
Кайл Дж. ЛИНДСТРОМ
Original Assignee
Міннесота Майнінг Енд Мен'Юфекчурінг Компані
Миннесота Майнинг энд Меньюфекчуринг Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Міннесота Майнінг Енд Мен'Юфекчурінг Компані, Миннесота Майнинг энд Меньюфекчуринг Компани filed Critical Міннесота Майнінг Енд Мен'Юфекчурінг Компані
Publication of UA32546C2 publication Critical patent/UA32546C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

Винахід відноситься до якісного складу біологічно активних 1,2-заміщених 1Н-імідазо[4,5-с]-хінолін-4-амінів, які можуть бути використані як противірусні препарати, стимулятори продукції інтерферону і антибластомних препаратів.
UA94020490A 1991-03-01 1992-02-20 1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом UA32546C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66292691A 1991-03-01 1991-03-01
US68732691A 1991-04-18 1991-04-18
PCT/US1992/001305 WO1992015582A1 (en) 1991-03-01 1992-02-20 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES

Publications (1)

Publication Number Publication Date
UA32546C2 true UA32546C2 (uk) 2001-02-15

Family

ID=27098631

Family Applications (1)

Application Number Title Priority Date Filing Date
UA94020490A UA32546C2 (uk) 1991-03-01 1992-02-20 1,2-заміщені 1н-імідазо[4,5-с]хінолін-4-аміни, проміжні сполуки для їх синтезу, антивірусна фармацевтична композиція, спосіб лікування інфікованих ссавців, спосіб індукування біосинтезу інтерферону у ссавців, спосіб уповільнення росту бластом

Country Status (18)

Country Link
EP (2) EP0582581B1 (uk)
JP (1) JP2955019B2 (uk)
AT (2) ATE179711T1 (uk)
AU (2) AU658621B2 (uk)
CA (2) CA2289219C (uk)
CZ (1) CZ285050B6 (uk)
DE (2) DE69229114T2 (uk)
DK (2) DK0872478T3 (uk)
ES (2) ES2131070T3 (uk)
HU (5) HU222250B1 (uk)
IE (1) IE920605A1 (uk)
IL (2) IL114570A (uk)
NO (1) NO303729B1 (uk)
NZ (1) NZ241784A (uk)
PH (1) PH31614A (uk)
SG (2) SG70625A1 (uk)
UA (1) UA32546C2 (uk)
WO (1) WO1992015582A1 (uk)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2475487C2 (ru) * 2007-05-08 2013-02-20 Астразенека Аб Имидазохинолины с иммуномодулирующими свойствами
EA029926B1 (ru) * 2008-03-24 2018-05-31 4ЭсЦэ АГ 1,2-дизамещенные 4-амино-имидазохинолины, содержащая их фармацевтическая композиция и их применение в качестве активаторов toll-подобных рецепторов 7 (варианты)

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Cited By (2)

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Publication number Priority date Publication date Assignee Title
RU2475487C2 (ru) * 2007-05-08 2013-02-20 Астразенека Аб Имидазохинолины с иммуномодулирующими свойствами
EA029926B1 (ru) * 2008-03-24 2018-05-31 4ЭсЦэ АГ 1,2-дизамещенные 4-амино-имидазохинолины, содержащая их фармацевтическая композиция и их применение в качестве активаторов toll-подобных рецепторов 7 (варианты)

Also Published As

Publication number Publication date
HU222111B1 (hu) 2003-04-28
IL114570A (en) 1996-10-31
IL101110A0 (en) 1992-11-15
NO933069D0 (no) 1993-08-27
ATE179711T1 (de) 1999-05-15
HU211242A9 (en) 1995-11-28
AU658621B2 (en) 1995-04-27
CZ285050B6 (cs) 1999-05-12
AU673309B2 (en) 1996-10-31
HU9701084D0 (en) 1997-08-28
CA2104782C (en) 2001-08-07
AU1566992A (en) 1992-10-06
AU2715795A (en) 1995-09-21
ES2186034T3 (es) 2003-05-01
ES2131070T3 (es) 1999-07-16
DE69229114T2 (de) 1999-11-04
DK0872478T3 (da) 2003-03-31
HU9701089D0 (en) 1997-08-28
DE69229114D1 (de) 1999-06-10
WO1992015582A1 (en) 1992-09-17
CA2289219C (en) 2003-05-20
SG70625A1 (en) 2000-02-22
PH31614A (en) 1999-01-12
JP2955019B2 (ja) 1999-10-04
CZ178893A3 (en) 1995-10-18
DK0582581T3 (da) 1999-11-08
HU222247B1 (hu) 2003-05-28
IL114570A0 (en) 1995-11-27
IE990988A1 (en) 2000-12-13
EP0582581B1 (en) 1999-05-06
EP0872478A3 (en) 1998-11-04
ATE229943T1 (de) 2003-01-15
IL101110A (en) 1995-12-08
IE920605A1 (en) 1992-09-09
CA2104782A1 (en) 1992-09-02
EP0872478A2 (en) 1998-10-21
HU222251B1 (hu) 2003-05-28
HU222250B1 (hu) 2003-05-28
NO933069L (no) 1993-11-01
JPH06504789A (ja) 1994-06-02
HU9302457D0 (en) 1993-11-29
HU9701083D0 (en) 1997-08-28
SG46492A1 (en) 1998-02-20
DE69232878T2 (de) 2003-11-20
EP0582581A1 (en) 1994-02-16
NO303729B1 (no) 1998-08-24
EP0872478B1 (en) 2002-12-18
DE69232878D1 (de) 2003-01-30
CA2289219A1 (en) 1992-09-02
HUT67026A (en) 1995-01-30
NZ241784A (en) 1995-06-27

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