UA116467C2 - Модулятори p2x7 - Google Patents

Модулятори p2x7

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Publication number
UA116467C2
UA116467C2 UAA201510002A UAA201510002A UA116467C2 UA 116467 C2 UA116467 C2 UA 116467C2 UA A201510002 A UAA201510002 A UA A201510002A UA A201510002 A UAA201510002 A UA A201510002A UA 116467 C2 UA116467 C2 UA 116467C2
Authority
UA
Ukraine
Prior art keywords
iib
iia
formulas
compounds
modulators
Prior art date
Application number
UAA201510002A
Other languages
English (en)
Inventor
Вака Мануель Хесус Алькасар
Бретт Д. Еллісон
Хіл Хосе Ігнасіо Андрес
Кріста К. Кровіан
Хітер Р. Коут
Анхеліс Мері де
Сяоху Ден
Курт А. Дворак
Крістін Ф. Желен
Майкл А. Летавіч
Джиммі Т. Ліан
Нєєлакандха С. Мані
Джейсон К. Рех
Бред М. Савалль
Акінола Сойод-Джонсон
Бріс М. Стенн
Девін М. Свенсон
Джессіка Л. Уолл
Original Assignee
Янссен Фармацевтика Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Нв filed Critical Янссен Фармацевтика Нв
Publication of UA116467C2 publication Critical patent/UA116467C2/uk

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

Даний винахід стосується сполук формул І, Іа, IIа і IIb: EMBED MDLDrawOLE.MDLDrawObject.1 \s , Формула (І) та Формула (Іa) EMBED MDLDrawOLE.MDLDrawObject.1 \s , EMBED MDLDrawOLE.MDLDrawObject.1 \s . Формула (ІІа) Формула (ІІb) Винахід також стосується фармацевтичних композицій, що містять сполуки формул І, Іа, IIа і IIb. Способи отримання та використання сполук формул І, Іа, IIа і IIb також входять в обсяг цього винаходу.
UAA201510002A 2013-03-14 2014-03-14 Модулятори p2x7 UA116467C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361786260P 2013-03-14 2013-03-14
PCT/US2014/027522 WO2014152604A1 (en) 2013-03-14 2014-03-14 P2x7 modulators

Publications (1)

Publication Number Publication Date
UA116467C2 true UA116467C2 (uk) 2018-03-26

Family

ID=50543353

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UAA201510002A UA116467C2 (uk) 2013-03-14 2014-03-14 Модулятори p2x7

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US (8) US9066946B2 (uk)
EP (3) EP3239151B1 (uk)
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KR (4) KR102516711B1 (uk)
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