MX364069B - Moduladores de la proteína activadora de 5-lipoxigenasa. - Google Patents
Moduladores de la proteína activadora de 5-lipoxigenasa.Info
- Publication number
- MX364069B MX364069B MX2015010106A MX2015010106A MX364069B MX 364069 B MX364069 B MX 364069B MX 2015010106 A MX2015010106 A MX 2015010106A MX 2015010106 A MX2015010106 A MX 2015010106A MX 364069 B MX364069 B MX 364069B
- Authority
- MX
- Mexico
- Prior art keywords
- flap modulators
- compounds
- formula
- modulators
- flap
- Prior art date
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- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
Abstract
La presente invención se refiere a los compuestos de la Fórmula (I), (ver Fórmula) o una forma de este, en donde el anillo A, R1, L y R2 son como se definen en la presente descripción, útiles como moduladores de la FLAP; la invención se refiere, además, a composiciones farmacéuticas que comprenden los compuestos de la Fórmula (I); los métodos para preparar y usar los compuestos de la Fórmula (I) están también dentro del alcance de la invención.
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US201361760615P | 2013-02-04 | 2013-02-04 | |
US201361798951P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/014088 WO2014121040A1 (en) | 2013-02-04 | 2014-01-31 | Flap modulators |
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MX364069B true MX364069B (es) | 2019-04-10 |
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US (4) | US9073876B2 (es) |
EP (1) | EP2951169B1 (es) |
JP (1) | JP6328145B2 (es) |
KR (1) | KR20160004258A (es) |
CN (1) | CN105073742B (es) |
AU (2) | AU2014212193B2 (es) |
BR (1) | BR112015018504A2 (es) |
CA (1) | CA2899904A1 (es) |
EA (1) | EA030404B1 (es) |
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MX (1) | MX364069B (es) |
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UY (1) | UY35305A (es) |
WO (1) | WO2014121040A1 (es) |
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CN108026079B (zh) * | 2015-09-24 | 2020-09-22 | 株式会社Lg化学 | 化合物和包含其的有机发光器件 |
CN108329330B (zh) * | 2017-01-20 | 2021-05-04 | 复旦大学 | 2-苄氧苯基噁唑并吡啶类化合物及其药物用途 |
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-
2014
- 2014-01-29 TW TW103103363A patent/TWI644899B/zh not_active IP Right Cessation
- 2014-01-31 JP JP2015556159A patent/JP6328145B2/ja not_active Expired - Fee Related
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- 2014-01-31 KR KR1020157024124A patent/KR20160004258A/ko not_active Application Discontinuation
- 2014-01-31 CN CN201480019599.1A patent/CN105073742B/zh not_active Expired - Fee Related
- 2014-01-31 BR BR112015018504A patent/BR112015018504A2/pt not_active Application Discontinuation
- 2014-01-31 US US14/169,642 patent/US9073876B2/en not_active Expired - Fee Related
- 2014-01-31 CA CA2899904A patent/CA2899904A1/en not_active Abandoned
- 2014-01-31 EP EP14704506.6A patent/EP2951169B1/en active Active
- 2014-01-31 US US14/765,552 patent/US9732093B2/en not_active Expired - Fee Related
- 2014-01-31 MX MX2015010106A patent/MX364069B/es active IP Right Grant
- 2014-01-31 AU AU2014212193A patent/AU2014212193B2/en not_active Ceased
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2015
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2016
- 2016-05-13 HK HK16105491.5A patent/HK1217489A1/zh unknown
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- 2017-08-02 US US15/667,420 patent/US10047101B2/en not_active Expired - Fee Related
- 2017-08-10 AU AU2017213500A patent/AU2017213500B2/en not_active Ceased
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US10047101B2 (en) | 2018-08-14 |
HK1217489A1 (zh) | 2017-01-13 |
US20140221310A1 (en) | 2014-08-07 |
BR112015018504A2 (pt) | 2017-07-18 |
CN105073742B (zh) | 2017-08-08 |
US9732093B2 (en) | 2017-08-15 |
US20150252008A1 (en) | 2015-09-10 |
AU2017213500B2 (en) | 2019-02-28 |
EP2951169A1 (en) | 2015-12-09 |
JP6328145B2 (ja) | 2018-05-23 |
WO2014121040A8 (en) | 2015-02-12 |
KR20160004258A (ko) | 2016-01-12 |
US20170327514A1 (en) | 2017-11-16 |
EA030404B1 (ru) | 2018-07-31 |
AU2014212193A1 (en) | 2015-07-30 |
CN105073742A (zh) | 2015-11-18 |
US9926333B2 (en) | 2018-03-27 |
US9073876B2 (en) | 2015-07-07 |
TWI644899B (zh) | 2018-12-21 |
UY35305A (es) | 2014-08-29 |
JP2016514089A (ja) | 2016-05-19 |
CA2899904A1 (en) | 2014-08-07 |
AU2017213500A1 (en) | 2017-08-31 |
EA201591451A1 (ru) | 2015-12-30 |
US20150368270A1 (en) | 2015-12-24 |
WO2014121040A1 (en) | 2014-08-07 |
TW201444799A (zh) | 2014-12-01 |
EP2951169B1 (en) | 2019-08-28 |
AU2014212193B2 (en) | 2017-06-15 |
MX2015010106A (es) | 2016-01-14 |
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