ME02802B - P2x7 modulatori - Google Patents

P2x7 modulatori

Info

Publication number
ME02802B
ME02802B MEP-2017-160A MEP2017160A ME02802B ME 02802 B ME02802 B ME 02802B ME P2017160 A MEP2017160 A ME P2017160A ME 02802 B ME02802 B ME 02802B
Authority
ME
Montenegro
Prior art keywords
modulators
Prior art date
Application number
MEP-2017-160A
Other languages
German (de)
English (en)
French (fr)
Inventor
Vaca Manuel Jesus Alcazar
Brett D Allison
Gil Jose Ignacio Andres
Christa C Chrovian
Heather R Coate
Angelis Meri De
Xiaohu Deng
Curt A Dvorak
Christine F Gelin
Michael A Letavic
Jimmy T Liang
Neelakandha S Mani
Jason C Rech
Brad M Savall
Akinola Soyode-Johnson
Brice M Stenne
Devin M Swanson
Jessica L Wall
Original Assignee
Lutovac Vuk
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lutovac Vuk, Janssen Pharmaceutica Nv filed Critical Lutovac Vuk
Publication of ME02802B publication Critical patent/ME02802B/me

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    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
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    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • AHUMAN NECESSITIES
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    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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  • Diabetes (AREA)
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  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
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  • Obesity (AREA)
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MEP-2017-160A 2013-03-14 2014-03-14 P2x7 modulatori ME02802B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361786260P 2013-03-14 2013-03-14
EP14718857.7A EP2970267B3 (en) 2013-03-14 2014-03-14 P2x7 modulators
PCT/US2014/027522 WO2014152604A1 (en) 2013-03-14 2014-03-14 P2x7 modulators

Publications (1)

Publication Number Publication Date
ME02802B true ME02802B (me) 2018-01-20

Family

ID=50543353

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2017-160A ME02802B (me) 2013-03-14 2014-03-14 P2x7 modulatori

Country Status (33)

Country Link
US (8) US10112937B2 (me)
EP (3) EP3495365A1 (me)
JP (1) JP6293861B2 (me)
KR (4) KR102516711B1 (me)
CN (2) CN105209464B (me)
AR (2) AR095530A1 (me)
AU (5) AU2014239291B2 (me)
BR (1) BR112015023142B1 (me)
CA (1) CA2906085C (me)
CL (3) CL2015002655A1 (me)
CY (1) CY1119110T1 (me)
DK (2) DK2970267T6 (me)
EA (1) EA028816B1 (me)
ES (2) ES2704024T3 (me)
HK (1) HK1218541A1 (me)
HR (1) HRP20171168T4 (me)
HU (1) HUE032877T2 (me)
IL (1) IL240880B (me)
JO (1) JO3773B1 (me)
LT (1) LT2970267T (me)
ME (1) ME02802B (me)
MX (2) MX364796B (me)
PH (1) PH12015501930A1 (me)
PL (1) PL2970267T6 (me)
PT (2) PT3239151T (me)
RS (1) RS56315B2 (me)
SG (2) SG11201507259UA (me)
SI (1) SI2970267T1 (me)
TW (2) TWI644671B (me)
UA (1) UA116467C2 (me)
UY (3) UY39887A (me)
WO (1) WO2014152604A1 (me)
ZA (1) ZA201507627B (me)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI644671B (zh) 2013-03-14 2018-12-21 比利時商健生藥品公司 P2x7調節劑
WO2014152537A1 (en) 2013-03-14 2014-09-25 Janssen Pharmaceutica Nv P2x7 modulators
EA029052B1 (ru) 2013-03-14 2018-02-28 Бёрингер Ингельхайм Интернациональ Гмбх Замещенные (бензилцианометил)амиды 2-азабицикло[2.2.1]гептан-3-карбоновых кислот в качестве ингибиторов катепсина с
TWI627174B (zh) 2013-03-14 2018-06-21 比利時商健生藥品公司 P2x7調控劑
EP3112366B1 (en) 2013-03-14 2018-02-28 Janssen Pharmaceutica NV P2x7 modulators
GB201321748D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
WO2015172196A1 (en) * 2014-05-13 2015-11-19 Monash University Heterocyclic compounds and use of same
EA034015B1 (ru) 2014-09-12 2019-12-19 Янссен Фармацевтика Нв Модуляторы р2х7
WO2016038007A1 (en) 2014-09-12 2016-03-17 Boehringer Ingelheim International Gmbh Spirocyclic inhibitors of cathepsin c
PL3287443T3 (pl) 2015-04-24 2022-02-21 Shionogi & Co., Ltd 6-członowa pochodna heterocykliczna i kompozycja farmaceutyczna ją zawierająca
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