UA110961C2 - КОМБІНАЦІЯ ІНГІБІТОРУ ФОСФАТИДИЛІНОЗИТ-3-КІНАЗИ (PI3K) І ІНГІБІТОРУ mTOR - Google Patents

КОМБІНАЦІЯ ІНГІБІТОРУ ФОСФАТИДИЛІНОЗИТ-3-КІНАЗИ (PI3K) І ІНГІБІТОРУ mTOR Download PDF

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Publication number
UA110961C2
UA110961C2 UAA201311138A UAA201311138A UA110961C2 UA 110961 C2 UA110961 C2 UA 110961C2 UA A201311138 A UAA201311138 A UA A201311138A UA A201311138 A UAA201311138 A UA A201311138A UA 110961 C2 UA110961 C2 UA 110961C2
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UA
Ukraine
Prior art keywords
compound
everolimus
combination
shi
pharmaceutically acceptable
Prior art date
Application number
UAA201311138A
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English (en)
Ukrainian (uk)
Inventor
Крістіна Фрітш
Карлос Гарсія-Ечеверрія
Ксіжонг Хуанг
Совер-Мішель Мера
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Новартіс Аг
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46018130&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA110961(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Новартіс Аг filed Critical Новартіс Аг
Publication of UA110961C2 publication Critical patent/UA110961C2/uk

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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UAA201311138A 2011-04-25 2012-04-23 КОМБІНАЦІЯ ІНГІБІТОРУ ФОСФАТИДИЛІНОЗИТ-3-КІНАЗИ (PI3K) І ІНГІБІТОРУ mTOR UA110961C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161478572P 2011-04-25 2011-04-25
PCT/US2012/034647 WO2012148846A1 (en) 2011-04-25 2012-04-23 Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor

Publications (1)

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UA110961C2 true UA110961C2 (uk) 2016-03-10

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Family Applications (1)

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UAA201311138A UA110961C2 (uk) 2011-04-25 2012-04-23 КОМБІНАЦІЯ ІНГІБІТОРУ ФОСФАТИДИЛІНОЗИТ-3-КІНАЗИ (PI3K) І ІНГІБІТОРУ mTOR

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US (3) US20140066474A1 (enExample)
EP (1) EP2701703A1 (enExample)
JP (2) JP6086902B2 (enExample)
KR (1) KR101925656B1 (enExample)
CN (1) CN103491955B (enExample)
AR (1) AR086481A1 (enExample)
AU (2) AU2012250010A1 (enExample)
BR (1) BR112013027486A2 (enExample)
CA (1) CA2833962A1 (enExample)
CL (1) CL2013003078A1 (enExample)
CO (1) CO6801759A2 (enExample)
EA (1) EA025948B1 (enExample)
EC (1) ECSP13012994A (enExample)
GT (1) GT201300263A (enExample)
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PE (1) PE20140601A1 (enExample)
PH (1) PH12013502077A1 (enExample)
SG (1) SG193919A1 (enExample)
TN (1) TN2013000392A1 (enExample)
TW (1) TWI602567B (enExample)
UA (1) UA110961C2 (enExample)
WO (1) WO2012148846A1 (enExample)
ZA (1) ZA201306973B (enExample)

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CN105246482A (zh) * 2013-03-15 2016-01-13 因特利凯有限责任公司 激酶抑制剂的组合及其用途
US20150140036A1 (en) * 2013-11-13 2015-05-21 Novartis Institutes For Biomedical Research, Inc. Low, immune enhancing, dose mtor inhibitors and uses thereof
US20170165246A1 (en) * 2014-02-11 2017-06-15 Novartis Ag Pharmaceutical combinations comprising a pi3k inhibitor for the treatment of cancer
WO2015148626A1 (en) * 2014-03-26 2015-10-01 Millennium Pharmaceuticals, Inc. Treatment of fibrotic disorders
RU2690685C2 (ru) * 2014-10-03 2019-06-05 Новартис Аг Фармацевтические композиции, содержащие алпелисиб
US20160339030A1 (en) * 2015-05-19 2016-11-24 University Of Maryland, Baltimore Treatment agents for inhibiting hiv and cancer in hiv infected patients
JP6691337B2 (ja) * 2016-02-29 2020-04-28 学校法人北里研究所 膀胱癌患者の予後を予測するための方法
GB202010627D0 (en) * 2020-07-10 2020-08-26 Qbd (Qs-Ip) Ltd Blocking method

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RU2538683C2 (ru) * 2008-10-31 2015-01-10 Новартис Аг КОМБИНАЦИЯ ИНГИБИТОРА ФОСФАТИДИЛИНОЗИТОЛ-3-КИНАЗЫ (Р13К) И ИНГИБИТОРА mTOR

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AU2016202372B2 (en) 2017-07-20
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EA025948B1 (ru) 2017-02-28
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