TWI831776B - 腫瘤浸潤性淋巴細胞之基因編輯和彼於免疫治療之用途 - Google Patents
腫瘤浸潤性淋巴細胞之基因編輯和彼於免疫治療之用途 Download PDFInfo
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- TWI831776B TWI831776B TW108114792A TW108114792A TWI831776B TW I831776 B TWI831776 B TW I831776B TW 108114792 A TW108114792 A TW 108114792A TW 108114792 A TW108114792 A TW 108114792A TW I831776 B TWI831776 B TW I831776B
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862663885P | 2018-04-27 | 2018-04-27 | |
| US62/663,885 | 2018-04-27 | ||
| US201862680821P | 2018-06-05 | 2018-06-05 | |
| US62/680,821 | 2018-06-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW202014195A TW202014195A (zh) | 2020-04-16 |
| TWI831776B true TWI831776B (zh) | 2024-02-11 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW108114792A TWI831776B (zh) | 2018-04-27 | 2019-04-26 | 腫瘤浸潤性淋巴細胞之基因編輯和彼於免疫治療之用途 |
| TW113104638A TWI911643B (zh) | 2018-04-27 | 2019-04-26 | 腫瘤浸潤性淋巴細胞之基因編輯和彼於免疫治療之用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW113104638A TWI911643B (zh) | 2018-04-27 | 2019-04-26 | 腫瘤浸潤性淋巴細胞之基因編輯和彼於免疫治療之用途 |
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| Country | Link |
|---|---|
| US (6) | US12642268B2 (enExample) |
| EP (1) | EP3784254A1 (enExample) |
| JP (1) | JP2021521846A (enExample) |
| KR (2) | KR20210005138A (enExample) |
| CN (1) | CN112368003A (enExample) |
| AU (2) | AU2019257749B2 (enExample) |
| BR (1) | BR112020021660A2 (enExample) |
| CA (1) | CA3098303A1 (enExample) |
| IL (1) | IL278231A (enExample) |
| MA (1) | MA52533A (enExample) |
| MX (1) | MX2020011134A (enExample) |
| SG (1) | SG11202010319RA (enExample) |
| TW (2) | TWI831776B (enExample) |
| WO (1) | WO2019210131A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201522097D0 (en) | 2015-12-15 | 2016-01-27 | Cellular Therapeutics Ltd | Cells |
| GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| EP3765094A4 (en) | 2018-03-15 | 2021-12-22 | KSQ Therapeutics, Inc. | GENE REGULATORY COMPOSITIONS AND PROCEDURES FOR IMPROVED IMMUNOTHERAPY |
| IL282775B1 (en) * | 2018-11-05 | 2026-05-01 | Iovance Biotherapeutics Inc | Selection of enhanced carrier-reactive T cells |
| EP4048295A1 (en) * | 2019-10-25 | 2022-08-31 | Iovance Biotherapeutics, Inc. | Gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| IL293350A (en) * | 2019-11-27 | 2022-07-01 | Myst Therapeutics Llc | Method of producing tumor-reactive t cell composition using modulatory agents |
| JP2023507432A (ja) * | 2019-12-20 | 2023-02-22 | インスティル バイオ (ユーケイ) リミテッド | 腫瘍浸潤リンパ球を単離するためのデバイスおよび方法ならびにそれらの使用 |
| WO2021167908A1 (en) * | 2020-02-17 | 2021-08-26 | Board Of Regents, The University Of Texas System | Methods for expansion of tumor infiltrating lymphocytes and use thereof |
| JP7840569B2 (ja) | 2020-02-17 | 2026-04-06 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | ヒト4-1bbアゴニスト抗体およびその使用方法 |
| EP4110799B1 (en) * | 2020-02-27 | 2024-11-06 | Turnstone Biologics Corp. | Methods for ex vivo enrichment and expansion of tumor reactive t cells and related compositions thereof |
| WO2021222479A1 (en) | 2020-04-28 | 2021-11-04 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| WO2021226061A1 (en) | 2020-05-04 | 2021-11-11 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| EP4146793A1 (en) * | 2020-05-04 | 2023-03-15 | Iovance Biotherapeutics, Inc. | Selection of improved tumor reactive t-cells |
| WO2022087324A1 (en) * | 2020-10-22 | 2022-04-28 | Iovance Biotherapeutics, Inc. | Cell culture system and methods of using the same |
| US20240123067A1 (en) * | 2020-12-17 | 2024-04-18 | Iovance Biotherapeutics, Inc. | Treatment of cancers with tumor infiltrating lymphocyte therapies |
| CA3205464A1 (en) * | 2020-12-18 | 2022-06-23 | Instil Bio (Uk) Limited | Processing of tumor infiltrating lymphocytes |
| CN114686430A (zh) * | 2020-12-31 | 2022-07-01 | 上海赛比曼生物科技有限公司 | 一种制备til的方法 |
| CA3206549A1 (en) * | 2021-01-29 | 2022-08-04 | Frederick G. Vogt | Methods of making modified tumor infiltrating lymphocytes and their use in adoptive cell therapy |
| US20240299540A1 (en) * | 2021-02-05 | 2024-09-12 | Iovance Biotherapeutics, Inc. | Adjuvant therapy for cancer |
| TW202304480A (zh) * | 2021-03-19 | 2023-02-01 | 美商艾歐凡斯生物治療公司 | 腫瘤浸潤淋巴球(til)中之與cd39/cd69選擇及基因剔除相關之til擴增之方法 |
| CN118019546A (zh) * | 2021-03-23 | 2024-05-10 | 艾欧凡斯生物治疗公司 | 肿瘤浸润淋巴细胞的cish基因编辑及其在免疫疗法中的用途 |
| EP4314253A2 (en) | 2021-03-25 | 2024-02-07 | Iovance Biotherapeutics, Inc. | Methods and compositions for t-cell coculture potency assays and use with cell therapy products |
| KR102666931B1 (ko) * | 2021-03-30 | 2024-05-20 | 주식회사 네오젠티씨 | 면역세포 조성물을 생산하는 방법 |
| AU2022263418A1 (en) | 2021-04-19 | 2023-10-26 | Iovance Biotherapeutics, Inc. | Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies |
| US20240269180A1 (en) * | 2021-05-17 | 2024-08-15 | Iovance Biotherapeutics, Inc. | Pd-1 gene-edited tumor infiltrating lymphocytes and uses of same in immunotherapy |
| CN113244389B (zh) * | 2021-07-06 | 2021-09-17 | 诺赛联合(北京)生物医学科技有限公司 | 一种TILs细胞制备方法及在肿瘤治疗的用途 |
| EP4469065A1 (en) * | 2022-01-28 | 2024-12-04 | Iovance Biotherapeutics, Inc. | Cytokine associated tumor infiltrating lymphocytes compositions and methods |
| JP2025503987A (ja) * | 2022-01-28 | 2025-02-06 | アイオバンス バイオセラピューティクス,インコーポレイテッド | ペイロードを発現するように操作された腫瘍浸潤リンパ球 |
| CN118401651A (zh) * | 2022-01-29 | 2024-07-26 | 苏州沙砾生物科技有限公司 | 一种修饰的肿瘤浸润淋巴细胞及其用途 |
| EP4289939A1 (en) * | 2022-06-10 | 2023-12-13 | Apeiron Biologics AG | Population of transfected immune cells and method for their production |
| JP2024012879A (ja) * | 2022-07-19 | 2024-01-31 | 国立大学法人三重大学 | 腫瘍反応性t細胞の製造方法 |
| EP4565683A1 (en) | 2022-08-01 | 2025-06-11 | Iovance Biotherapeutics, Inc. | Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies |
| JP2025531877A (ja) * | 2022-09-09 | 2025-09-25 | アイオバンス バイオセラピューティクス,インコーポレイテッド | Pd-1/tigit talenダブルノックダウンを使用したtil製品を生成するためのプロセス |
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| MA52533A (fr) | 2021-03-03 |
| CN112368003A (zh) | 2021-02-12 |
| US12031157B2 (en) | 2024-07-09 |
| US20220403333A1 (en) | 2022-12-22 |
| US11866688B2 (en) | 2024-01-09 |
| AU2019257749B2 (en) | 2026-02-12 |
| US20220396768A1 (en) | 2022-12-15 |
| US12024718B2 (en) | 2024-07-02 |
| EP3784254A1 (en) | 2021-03-03 |
| SG11202010319RA (en) | 2020-11-27 |
| BR112020021660A2 (pt) | 2021-02-02 |
| AU2019257749A1 (en) | 2020-10-22 |
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