TWI796746B - 用於治療輕鏈型類澱粉變性症及其他cd38-陽性血液惡性疾病之抗-cd38抗體 - Google Patents

用於治療輕鏈型類澱粉變性症及其他cd38-陽性血液惡性疾病之抗-cd38抗體 Download PDF

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TWI796746B
TWI796746B TW110128156A TW110128156A TWI796746B TW I796746 B TWI796746 B TW I796746B TW 110128156 A TW110128156 A TW 110128156A TW 110128156 A TW110128156 A TW 110128156A TW I796746 B TWI796746 B TW I796746B
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antibody
seq
cells
light chain
patient
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TW202211931A (zh
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查克拉 考萊根
雷蒙 康曼卓
帕盧 多西
迅 馬
艾咪 賽瑟
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美商健生生物科技公司
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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TW110128156A 2015-05-20 2016-10-28 用於治療輕鏈型類澱粉變性症及其他cd38-陽性血液惡性疾病之抗-cd38抗體 TWI796746B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562164206P 2015-05-20 2015-05-20
US201562214586P 2015-09-04 2015-09-04
US15/160,476 US10766965B2 (en) 2015-05-20 2016-05-20 Anti-CD38 antibodies for treatment of light chain amyloidosis and other CD38-positive hematological malignancies
PCT/US2016/033544 WO2016187546A1 (en) 2015-05-20 2016-05-20 Anti-cd38 antibodies for treatment of light chain amyloidosis and other cd38-positive hematological malignancies
US15/160,476 2016-05-20
WOPCT/US16/33544 2016-05-20

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Publication Number Publication Date
TW202211931A TW202211931A (zh) 2022-04-01
TWI796746B true TWI796746B (zh) 2023-03-21

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TW110128156A TWI796746B (zh) 2015-05-20 2016-10-28 用於治療輕鏈型類澱粉變性症及其他cd38-陽性血液惡性疾病之抗-cd38抗體
TW105134916A TWI737642B (zh) 2015-05-20 2016-10-28 用於治療輕鏈型類澱粉變性症及其他ｃｄ３８-陽性血液惡性疾病之抗-ｃｄ３８抗體
TW112110649A TW202402324A (zh) 2015-05-20 2016-10-28 用於治療輕鏈型類澱粉變性症及其他cd38-陽性血液惡性疾病之抗-cd38抗體

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TW105134916A TWI737642B (zh) 2015-05-20 2016-10-28 用於治療輕鏈型類澱粉變性症及其他ｃｄ３８-陽性血液惡性疾病之抗-ｃｄ３８抗體
TW112110649A TW202402324A (zh) 2015-05-20 2016-10-28 用於治療輕鏈型類澱粉變性症及其他cd38-陽性血液惡性疾病之抗-cd38抗體

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