TWI784288B - Ｆｃ區之多肽及包含其之Ｆｃ融合蛋白 - Google Patents

Ｆｃ區之多肽及包含其之Ｆｃ融合蛋白 Download PDF

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TWI784288B
TWI784288B TW109121895A TW109121895A TWI784288B TW I784288 B TWI784288 B TW I784288B TW 109121895 A TW109121895 A TW 109121895A TW 109121895 A TW109121895 A TW 109121895A TW I784288 B TWI784288 B TW I784288B
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mutein
cells
seq
cell
amino acid
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TW202115106A (zh
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馬克 A 葛文
古南斯卡瑞恩 柯南
李麗
喬許亞 T 皮爾森
馬格瑞特 卡羅
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美商安美基公司
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/00—Immunoglobulins specific features
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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TW109121895A 2013-03-14 2014-03-14 Ｆｃ區之多肽及包含其之Ｆｃ融合蛋白 TWI784288B (zh)

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TW109121895A TWI784288B (zh) 2013-03-14 2014-03-14 Ｆｃ區之多肽及包含其之Ｆｃ融合蛋白
TW108117705A TWI709572B (zh) 2013-03-14 2014-03-14 用於t調節細胞之擴展的介白素-2突變蛋白
TW103109295A TWI687435B (zh) 2013-03-14 2014-03-14 用於ｔ調節細胞之擴展的介白素-２突變蛋白

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TW103109295A TWI687435B (zh) 2013-03-14 2014-03-14 用於ｔ調節細胞之擴展的介白素-２突變蛋白

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