TWI778018B - 抗類胰蛋白酶抗體、其組合物及其用途 - Google Patents
抗類胰蛋白酶抗體、其組合物及其用途 Download PDFInfo
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- TWI778018B TWI778018B TW107104821A TW107104821A TWI778018B TW I778018 B TWI778018 B TW I778018B TW 107104821 A TW107104821 A TW 107104821A TW 107104821 A TW107104821 A TW 107104821A TW I778018 B TWI778018 B TW I778018B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12Y—ENZYMES
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- C07—ORGANIC CHEMISTRY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/00—Immunoglobulins specific features
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762457722P | 2017-02-10 | 2017-02-10 | |
| US62/457,722 | 2017-02-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201835105A TW201835105A (zh) | 2018-10-01 |
| TWI778018B true TWI778018B (zh) | 2022-09-21 |
Family
ID=61274365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW107104821A TWI778018B (zh) | 2017-02-10 | 2018-02-09 | 抗類胰蛋白酶抗體、其組合物及其用途 |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US10738131B2 (https=) |
| EP (1) | EP3580240A1 (https=) |
| JP (3) | JP6995127B2 (https=) |
| KR (1) | KR102362006B1 (https=) |
| CN (2) | CN110494453B (https=) |
| AR (1) | AR110873A1 (https=) |
| AU (1) | AU2018217816A1 (https=) |
| BR (1) | BR112019016595A2 (https=) |
| CA (1) | CA3051700A1 (https=) |
| CL (2) | CL2019002251A1 (https=) |
| CO (1) | CO2019009787A2 (https=) |
| CR (1) | CR20190387A (https=) |
| IL (1) | IL268249A (https=) |
| MA (1) | MA47459A (https=) |
| MX (1) | MX2019009485A (https=) |
| MY (1) | MY197534A (https=) |
| PE (1) | PE20191548A1 (https=) |
| PH (1) | PH12019501872A1 (https=) |
| RU (1) | RU2771485C2 (https=) |
| SG (1) | SG11201907364WA (https=) |
| TW (1) | TWI778018B (https=) |
| UA (1) | UA126574C2 (https=) |
| WO (1) | WO2018148585A1 (https=) |
| ZA (1) | ZA201905023B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6871948B2 (ja) | 2016-04-27 | 2021-05-19 | アッヴィ・インコーポレイテッド | 抗il−13抗体を使用する、il−13活性が有害である疾患の治療方法 |
| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| KR20220098056A (ko) | 2018-02-09 | 2022-07-08 | 제넨테크, 인크. | 비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법 |
| CN110006871A (zh) * | 2019-02-20 | 2019-07-12 | 常州大学 | 一个基于外源性组胺检测的细胞模型以及应用 |
| EP4009953A4 (en) * | 2019-08-07 | 2023-08-23 | Icahn School of Medicine at Mount Sinai | METHOD OF TREATMENT OF KELOIDS |
| CN114423454A (zh) * | 2019-09-20 | 2022-04-29 | 豪夫迈·罗氏有限公司 | 抗类胰蛋白酶抗体的给药 |
| KR102801198B1 (ko) * | 2021-06-28 | 2025-04-30 | (주) 넥셀 | 특발성 폐섬유증 예방 또는 치료용 폴리펩타이드 및 이를 포함하는 약학 조성물 |
| CN117897409A (zh) | 2021-08-13 | 2024-04-16 | 基因泰克公司 | 抗类胰蛋白酶抗体的给药 |
| CN117858898A (zh) * | 2021-08-27 | 2024-04-09 | 免疫医疗有限公司 | 用抗白介素-33抗体治疗慢性阻塞性肺病 |
| CN114515296B (zh) * | 2022-02-25 | 2024-01-12 | 和携科技有限公司 | 一种脂肪间充质干细胞分泌因子的制备方法 |
| EP4540284A2 (en) | 2022-06-17 | 2025-04-23 | Apogee Therapeutics, Inc. | Antibodies that bind interleukin 13 and methods of use |
| CA3251445A1 (en) * | 2022-06-29 | 2024-01-04 | Kashiv Biosciences, Llc | IMPROVED ANTIBODY ASSAY METHOD |
| CN118962135A (zh) * | 2024-08-13 | 2024-11-15 | 武汉大白小白科技有限公司 | 类胰蛋白酶快速定量试剂盒及其在鼻炎诊断产品中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744319A (en) * | 1995-11-08 | 1998-04-28 | Promega Corporation | Avian tryptase polyclonal antibody and purification method for use in human tryptase immunoassay |
Family Cites Families (124)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・2・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5770701A (en) | 1987-10-30 | 1998-06-23 | American Cyanamid Company | Process for preparing targeted forms of methyltrithio antitumor agents |
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