TWI668019B - 膜囊封奈米粒子及使用方法 - Google Patents
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- TWI668019B TWI668019B TW106100872A TW106100872A TWI668019B TW I668019 B TWI668019 B TW I668019B TW 106100872 A TW106100872 A TW 106100872A TW 106100872 A TW106100872 A TW 106100872A TW I668019 B TWI668019 B TW I668019B
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| EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| CN103429606A (zh) | 2010-10-01 | 2013-12-04 | 现代治疗公司 | 设计核酸及其使用方法 |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| EP3412282B1 (en) | 2011-06-02 | 2024-10-09 | The Regents of the University of California | Membrane encapsulated nanoparticles and method of use |
| WO2012174173A2 (en) * | 2011-06-13 | 2012-12-20 | President And Fellows Of Harvard College | Multi-color nanoscale imaging based on nanoparticle cathodoluminescence |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| KR20190099538A (ko) | 2011-10-03 | 2019-08-27 | 모더나 세라퓨틱스, 인코포레이티드 | 변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도 |
| EP4144378A1 (en) | 2011-12-16 | 2023-03-08 | ModernaTX, Inc. | Modified nucleoside, nucleotide, and nucleic acid compositions |
| US9702795B2 (en) * | 2012-01-17 | 2017-07-11 | The Scripps Research Institute | Apparatus and method for producing specimens for electron microscopy |
| WO2013109405A1 (en) * | 2012-01-17 | 2013-07-25 | The Scripps Research Institute | Preparation of specimen arrays on an em grid |
| AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| JP6450673B2 (ja) * | 2012-04-03 | 2019-01-09 | リニューロン・リミテッドＲｅＮｅｕｒｏｎ Ｌｉｍｉｔｅｄ | 幹細胞微粒子 |
| DK2922554T3 (en) | 2012-11-26 | 2022-05-23 | Modernatx Inc | Terminalt modificeret rna |
| EP2971010B1 (en) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10954489B2 (en) | 2013-06-04 | 2021-03-23 | The Regents Of The University Of California | Liver-mimetic device and method for simulation of hepatic function using such device |
| WO2015021390A2 (en) * | 2013-08-08 | 2015-02-12 | The Regents Of The University Of California | Nanoparticles leverage biological membranes to target pathogens for disease treatment and diagnosis |
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| BR112016007255A2 (pt) | 2013-10-03 | 2017-09-12 | Moderna Therapeutics Inc | polinucleotídeos que codificam receptor de lipoproteína de baixa densidade |
| WO2015084677A1 (en) | 2013-12-02 | 2015-06-11 | Arytha Biosciences, Llc | Toxoid preparation and uses thereof |
| US10098839B2 (en) | 2014-03-20 | 2018-10-16 | The Regents Of The University Of California | Hydrogel toxin-absorbing or binding nanoparticles |
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| TW201311297A (zh) | 2013-03-16 |
| CN103857387B (zh) | 2017-03-15 |
| EP3412282C0 (en) | 2024-10-09 |
| EP2714017A4 (en) | 2015-06-03 |
| JP6100762B2 (ja) | 2017-03-22 |
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| WO2013052167A2 (en) | 2013-04-11 |
| US20250049716A1 (en) | 2025-02-13 |
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| DK2714017T3 (en) | 2018-09-03 |
| EP3412282A1 (en) | 2018-12-12 |
| ES2685333T3 (es) | 2018-10-08 |
| EP2714017A2 (en) | 2014-04-09 |
| US20250017860A1 (en) | 2025-01-16 |
| CN107115314A (zh) | 2017-09-01 |
| US20250049715A1 (en) | 2025-02-13 |
| US20240252438A1 (en) | 2024-08-01 |
| EP3412282B1 (en) | 2024-10-09 |
| TWI638667B (zh) | 2018-10-21 |
| TW201729799A (zh) | 2017-09-01 |
| US12097290B2 (en) | 2024-09-24 |
| CN107115314B (zh) | 2022-04-29 |
| CA2873404A1 (en) | 2013-04-11 |
| HK1197016A1 (en) | 2015-01-02 |
| EP2714017B1 (en) | 2018-08-01 |
| CA2873404C (en) | 2022-08-30 |
| US20130337066A1 (en) | 2013-12-19 |
| HK1243002A1 (zh) | 2018-07-06 |
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