TWI571512B - 抗原類及針對人腸病毒之疫苗類 - Google Patents
抗原類及針對人腸病毒之疫苗類 Download PDFInfo
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- TWI571512B TWI571512B TW101140538A TW101140538A TWI571512B TW I571512 B TWI571512 B TW I571512B TW 101140538 A TW101140538 A TW 101140538A TW 101140538 A TW101140538 A TW 101140538A TW I571512 B TWI571512 B TW I571512B
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- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| TWI700295B (zh) | 2013-12-16 | 2020-08-01 | 馬來西亞商Ｍａｂ探索私人有限公司 | 對會感染人類之腸病毒具有專一性之抗體 |
| DK4023249T3 (da) | 2014-04-23 | 2025-01-13 | Modernatx Inc | Nukleinsyrevacciner |
| TWI686475B (zh) * | 2014-04-29 | 2020-03-01 | 財團法人國家衛生研究院 | 對抗腸病毒感染之基於腺病毒載體之疫苗 |
| CN111925423B (zh) * | 2014-11-07 | 2022-08-19 | 普莱柯生物工程股份有限公司 | 一种抗o型口蹄疫的疫苗组合物及其制备方法和应用 |
| CN106554965B (zh) * | 2015-09-28 | 2019-08-27 | 斯澳生物科技（苏州）有限公司 | 用于制备ev71病毒样颗粒的核酸构建体和方法 |
| CN105348391B (zh) * | 2015-11-03 | 2019-06-28 | 李越希 | 埃可病毒6型vp1蛋白特异性抗原表位及其融合蛋白的制备、应用 |
| CN105802923B (zh) * | 2016-04-14 | 2019-07-16 | 中国科学院生物物理研究所 | 一种重组脊髓灰质炎病毒样颗粒及其制备方法与应用 |
| SG10202010435XA (en) * | 2016-04-22 | 2020-11-27 | Integrated Research Associates Llc | Improved method for producing virus like particles |
| US20190224304A1 (en) * | 2016-10-07 | 2019-07-25 | Sentinext Therapeutics Sdn Bhd | Chimeric enterovirus virus-like particles |
| US20190247488A1 (en) | 2016-10-07 | 2019-08-15 | Sentinext Therapeutics Sdn Bhd | Expression cassettes and methods for obtaining enterovirus virus-like particles |
| KR102091372B1 (ko) | 2017-02-28 | 2020-05-27 | 대한민국 | 엔테로바이러스 71형 불활화 백신 및 이의 용도 |
| CN108624601B (zh) * | 2017-03-17 | 2023-08-11 | 中国科学院上海巴斯德研究所 | 酵母表达的柯萨奇病毒a10病毒样颗粒及其应用 |
| SG11201913826QA (en) * | 2017-07-03 | 2020-01-30 | Bharat Biotech Int Ltd | A synthetic polypeptide epitope based vaccine composition |
| CN108152511B (zh) * | 2017-12-20 | 2019-01-04 | 广州瑞辉生物科技股份有限公司 | 柯萨奇A16病毒抗原多肽及其IgM抗体检测试剂盒 |
| CN108424881B (zh) * | 2018-03-23 | 2021-07-27 | 中国食品药品检定研究院 | 一株肠道病毒68型及其在制备ev-d68型感染动物中的应用 |
| WO2020067027A1 (ja) * | 2018-09-28 | 2020-04-02 | 一般財団法人阪大微生物病研究会 | Ｖｌｐ発現ｃｈｏ細胞株の構築 |
| CN110045105B (zh) * | 2018-11-09 | 2022-04-26 | 广州市妇女儿童医疗中心 | 柯萨奇A16病毒IgA抗体量子点免疫荧光层析试纸条及试剂盒 |
| EP4582440A3 (en) * | 2018-12-21 | 2025-10-08 | The Regents of the University of California | Il-10-containing vaccines and uses thereof |
| CN110684781B (zh) * | 2019-06-24 | 2021-05-28 | 四川农业大学 | 一种3型鸭甲肝病毒突变基因isa-a117c-t1142a及构建方法 |
| CN112048004B (zh) * | 2020-07-14 | 2021-10-22 | 桂林医学院 | 一种柯萨奇病毒b5型病毒样颗粒、其制备方法及应用 |
| WO2022070210A1 (en) * | 2020-09-29 | 2022-04-07 | Bharat Biotech International Limited | Stable formulations of low abundance enteroviruses vaccines and process of manufacture thereof |
| CN114107392A (zh) * | 2021-11-22 | 2022-03-01 | 昆明理工大学 | 一种cvb5病毒类病毒样颗粒的制备方法 |
| CN115010813B (zh) * | 2022-05-19 | 2024-04-05 | 桂林医学院 | 一种肠道病毒71型病毒样颗粒、其制备方法及应用 |
| CN116200348A (zh) * | 2022-09-21 | 2023-06-02 | 武汉生物制品研究所有限责任公司 | 一种适应Vero细胞的柯萨奇病毒A10型毒株的构建方法及其应用 |
| US11826418B1 (en) | 2023-01-06 | 2023-11-28 | King Faisal University | Virus-like particle (VLP)-based vaccine against CVB4 |
| WO2025029700A1 (en) * | 2023-07-28 | 2025-02-06 | Modernatx, Inc. | Vlp enteroviral vaccines |
| CN117456519B (zh) * | 2023-12-22 | 2024-03-12 | 江西科益高新技术有限公司 | 一种用于工控安全的仿真光电靶标装置及其仿真方法 |
| CN120665160A (zh) * | 2025-08-21 | 2025-09-19 | 国药中生生物技术研究院有限公司 | 肠道病毒71型的突变体及其病毒样颗粒 |
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| NL8102740A (nl) | 1981-06-05 | 1983-01-03 | Nederlanden Staat | Virusvaccins en werkwijze ter bereiding daarvan. |
| WO2003046138A2 (en) * | 2001-11-26 | 2003-06-05 | Duke University | Genetically stable expression vector |
| US20050112095A1 (en) * | 2002-07-09 | 2005-05-26 | Tsu-An Hsu | Internal ribosome entry sites for recombinant protein expression |
| EP1479761A1 (en) * | 2003-05-21 | 2004-11-24 | PrimaGen Holding B.V. | New enterovirus, vaccines, medicaments and diagnostic kits |
| ES2310062B1 (es) * | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| CN101365480B (zh) * | 2005-11-01 | 2014-11-05 | 诺华疫苗和诊断有限两合公司 | 经由β-丙内酯处理的残留细胞DNA水平降低的细胞衍生病毒疫苗 |
| WO2008005777A2 (en) * | 2006-06-30 | 2008-01-10 | Novavax, Inc. | Methods of enhancing protein incorporation into virus like particles |
| RU2528858C2 (ru) * | 2008-08-28 | 2014-09-20 | Новартис Аг | Дисплей на поверхности клеток полипептидных изоформ на основе прочитывания терминирующего кодона |
| US8663951B2 (en) * | 2009-01-09 | 2014-03-04 | Academia Sinica | Method of producing virus-like particles of picornavirus using a small-ubiquitin-related fusion protein expression system |
| CN101831410B (zh) | 2009-03-09 | 2013-04-17 | 北京工业大学 | 重组肠病毒71型病毒样颗粒的制备方法 |
| GB0918375D0 (en) * | 2009-10-20 | 2009-12-02 | Animal Health Inst | Construct |
| WO2012108840A1 (en) * | 2011-02-08 | 2012-08-16 | Temasek Life Sciences Laboratory Limited | A novel expression cassette for efficient surface display of antigenic proteins |
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