SG11201913826QA - A synthetic polypeptide epitope based vaccine composition - Google Patents

A synthetic polypeptide epitope based vaccine composition

Info

Publication number
SG11201913826QA
SG11201913826QA SG11201913826QA SG11201913826QA SG11201913826QA SG 11201913826Q A SG11201913826Q A SG 11201913826QA SG 11201913826Q A SG11201913826Q A SG 11201913826QA SG 11201913826Q A SG11201913826Q A SG 11201913826QA SG 11201913826Q A SG11201913826Q A SG 11201913826QA
Authority
SG
Singapore
Prior art keywords
vaccine composition
synthetic polypeptide
based vaccine
polypeptide epitope
epitope based
Prior art date
Application number
SG11201913826QA
Inventor
Amit Raychoudhuri
Original Assignee
Bharat Biotech Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bharat Biotech Int Ltd filed Critical Bharat Biotech Int Ltd
Publication of SG11201913826QA publication Critical patent/SG11201913826QA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/135—Foot- and mouth-disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
    • C07K14/09—Foot-and-mouth disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
SG11201913826QA 2017-07-03 2018-07-03 A synthetic polypeptide epitope based vaccine composition SG11201913826QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201741023411 2017-07-03
PCT/IN2018/050433 WO2019008599A1 (en) 2017-07-03 2018-07-03 A synthetic polypeptide epitope based vaccine composition

Publications (1)

Publication Number Publication Date
SG11201913826QA true SG11201913826QA (en) 2020-01-30

Family

ID=64950826

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201913826QA SG11201913826QA (en) 2017-07-03 2018-07-03 A synthetic polypeptide epitope based vaccine composition

Country Status (6)

Country Link
US (1) US11273215B2 (en)
KR (1) KR20200024895A (en)
CN (1) CN111050795B (en)
AU (1) AU2018298499A1 (en)
SG (1) SG11201913826QA (en)
WO (1) WO2019008599A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109966482A (en) * 2019-01-28 2019-07-05 新乡医学院 A kind of hand-foot-and-mouth disease polypeptide vaccine, vaccine injecta and its preparation method and application
CN111171117B (en) * 2019-12-27 2022-04-15 深圳康泰生物制品股份有限公司 Purification process of recombinant CA16 virus-like particles, recombinant CA16 virus vaccine and preparation method thereof
KR20210117832A (en) * 2020-03-20 2021-09-29 강원대학교산학협력단 Vaccine composition comprising gla-se for hand-foot-and-mouth disease
CN112156183B (en) * 2020-08-21 2021-07-30 浙江皇冠科技有限公司 CpG composite adjuvant and application thereof as novel coronavirus vaccine adjuvant
WO2022070210A1 (en) * 2020-09-29 2022-04-07 Bharat Biotech International Limited Stable formulations of low abundance enteroviruses vaccines and process of manufacture thereof
CN112089831B (en) * 2020-11-04 2021-04-02 浙江普康生物技术股份有限公司 Preparation method of recombinant novel coronavirus subunit vaccine
CN113773371A (en) * 2021-09-16 2021-12-10 北京凯悦宁医药科技有限公司 VP1 protein, and preparation method and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU781238B2 (en) * 1999-04-13 2005-05-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Production of attenuated negative stranded RNA virus vaccines from cloned nucleotide sequences
EP2073839B1 (en) * 2006-09-01 2016-10-19 Bharat Biotech International Limited A vaccine for chikungunya virus infection
WO2011054011A2 (en) 2009-11-02 2011-05-05 The Trustees Of The University Of Pennsylvania Foot and mouth disease virus (fmdv) consensus proteins, coding sequences therefor and vaccines made therefrom
US9051361B2 (en) * 2010-08-17 2015-06-09 National Health Research Institutes Immunogenic compositions and uses thereof
CN102533860B (en) * 2012-01-10 2013-07-24 特菲(天津)生物医药科技有限公司 Foot and mouth disease vaccine and preparation method thereof
AR102547A1 (en) 2014-11-07 2017-03-08 Takeda Vaccines Inc VACCINES AGAINST DISEASE OF HANDS, FEET AND MOUTH AND MANUFACTURING METHODS AND THEIR USE

Also Published As

Publication number Publication date
KR20200024895A (en) 2020-03-09
CN111050795B (en) 2023-09-22
US20210220466A1 (en) 2021-07-22
WO2019008599A1 (en) 2019-01-10
CN111050795A (en) 2020-04-21
US11273215B2 (en) 2022-03-15
AU2018298499A1 (en) 2020-02-20

Similar Documents

Publication Publication Date Title
SG11201913826QA (en) A synthetic polypeptide epitope based vaccine composition
IL268920A (en) Peptide vaccines
IL268140A (en) Procoagulant antibodies
PL3207053T3 (en) Novel immunogenic peptides
IL275298B1 (en) Mitochondria-targeting peptides
IL256097A (en) Antibody epitope
SG11202010821TA (en) Vaccine composition
SG11202100579UA (en) Epitopes
SG11202005653RA (en) Novel peptide
IL281224A (en) Peptide vaccines
GB201719557D0 (en) Polypeptide
IL278830A (en) Reverse peptide vaccine
SG11202001557PA (en) Immunogenic peptide against group a streptococcus
GB201703529D0 (en) Vaccine composition
GB201700557D0 (en) Novel peptides
GB201811382D0 (en) Vaccine
GB201810052D0 (en) Polypeptide
GB201621907D0 (en) Antibody epitope
GB201814366D0 (en) Peptide vaccines
GB201814364D0 (en) Peptide vaccines
GB201814365D0 (en) Peptide vaccines
GB201814367D0 (en) Peptide Vaccines
IL267680A (en) Immunogenic composition comprising cyaa-derived polypeptide promoting a th1/th17-oriented immune response
ZA202005699B (en) A sunscreen composition
GB201807376D0 (en) HMCV Vaccine Composition